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| 1 | Optimization Transmission Theory and Technical Pathways that Describe Multiscale Urban Agglomeration Spaces显示文摘Urban agglomerations are spatial entities that promote the development of ‘new urbanization' processes within China. In this context, the concept of ‘multiscale urban agglomeration spaces' encompasses three linked levels: macroscale urban agglomerations, mesoscale cities, and microscale urban centers. Applying a series of multidisciplinary integrated research methods drawn from geography, urban planning, and architecture, this paper reveals two intensive utilization laws that can be generalized to apply to multiscale urban agglomeration spaces, top-to-bottom ‘positive transmission' linkage and inside-to-outside ‘negative transmission' movement. This paper also proposes optimization transmission theory and policy decision technical pathways that can be applied to these three urban agglomeration spatial scales. Specific technical pathways of transmission include intensive expansion and simulated decision-making in macroscale urban agglomerations, ecology, production, and living space intensive layout and dynamic decision-making in mesoscale cities, and four cores(i.e., ‘single, ring, axis, and pole core') progressive linkage and intensive optimization decision-making in microscale urban centers. The theory and technical pathways proposed in this paper solve the technical problem of optimization and provide intensive methods that can be applied not only at the individual level but also at multiple scales in urban agglomeration spaces. This study also advances a series of comprehensive technical solutions that can be applied to both compact and smart growth cities as well as to urban agglomerations. Solid theoretical support is provided for the optimization of Chinese land development, urbanization, agricultural development, and ecological security. | FANG Chuanglin YANG Junyan FANG Jiawen HUANG Xiejun ZHOU Yi | 2018 | Chinese Geographical Science2018，28，4： | 14 |
| 2 | CapOX as neoadjuvant chemotherapy for locally advanced operable colon cancer patients: a prospective single-arm phase Ⅱ trial显示文摘Objective: The aim of this prospective, single-arm phase II trial was to confirm the safety and efficacy of neoadjuvant chemotherapy(NAC) using oxaliplatin plus capecitabine(Cap OX) for patients with operable locally advanced colon cancer(CC).Methods: Patients with computed tomography-defined T4 or lymph node-positive CCs were enrolled. After radiological staging, patients were treated with at least 2 cycles of NAC consisting of 130 mg/m2 oxaliplatin on d 1,plus 1,000 mg/m2 capecitabine twice daily for 14 d every 3 weeks, followed by surgery, and then with the rest cycles of adjuvant chemotherapy. Radiological response was evaluated after 2 cycles of NAC. Tumor response, treatment toxicity, and surgical complications were recorded. The pathological response to therapy was evaluated according to the tumor regression grade(TRG) score. The primary endpoint was pathologic tumor response. This trial is registered in Clinical Trials.gov(No: NCT02415829).Results: Forty-seven patients were enrolled in the study. Forty-two patients completed the planned treatments.The total radiological response rate was 68%(32/47), including complete and partial response rates of 2%(1/47)and 66%(31/47), respectively. Stable disease was observed in 32%(15/47) and progressive disease was observed in none. Complete pathologic response, major regression, and at least moderate regression were achieved in 1(2%), 2(4%), and 29(62%) patients, respectively. Four patients developed grade 3 treatment toxicities. One patient with wound infection occurred after operation(1/47, 2%). There was no treatment-related death.Conclusions: Our results suggest that NAC with Cap OX is an effective and safe treatment option for patients with locally advanced CCs. | Fangqi Liu Li Yang Yuchen Wu Cong Li Jiang Zhao Adili Keranmu Hongtu Zheng Dan Huang Lei Wang Tong Tong Junyan Xu Ji Zhu Sanjun Cai Ye Xu | 2016 | Chinese Journal of Cancer Research2016，28，6： | 14 |
| 3 | Immunomodulatory effect of human amniotic epithelial cells on restoration of ovarian function in mice with autoimmune ovarian disease显示文摘Autoimmune ovarian disease(AOD)is considered to be a major cause of premature ovarian failure(POF).The immunomodulatory properties of human amniotic epithelial cells(hAECs)have been studied in many disease models.We previously reported that hAECs restored ovarian function in chemotherapy-induced POF mice,but the immunomodulatory mechanism of hAECs is still unclear.To investigate the effect of hAECs on recipient mice,especially on regulatory Treg cells,hAECs and hAEC-conditioned medium(hAEC-CM)were intravenously injected into AOD mice immunized with zona pellucida protein 3 peptides(pZP3).Ovarian function was evaluated through estrous cycle,hormone secretion,follicle development,and cell apoptosis analysis.Immune cells including CD3,CD4,CD8 and Treg cells in the spleens were tested by flow cytometry.To elucidate the effect of hAEC-CM on macrophage function,inflammation model in vitrowas established in RAW264.7 cells induced by lipopolysaccharide(LPS).hAECs and hAEC-CM regulated estrous cycles,promoted follicle development,ameliorated cell apoptosis and fibrosis in ovaries of AOD mice.In addition,hAECs significantly reversed the decrease of pZP3-induced Treg cells in the spleens.In vitro,hAEC-CM significantly inhibited the inflammatory reaction induced by LPS in RAW264.7 cells via up-regulating the expression of M2 macrophage genes.Further study demonstrated that hAECsecreted transforming growth factor-beta and macrophage inhibitory factor played important roles in the macrophage polarization and migration under inflammatory stimulation.Taken together,hAECs restored ovarian function by up-regulating Treg cells in the spleens and reduced the inflammatory reaction via modulating the activated macrophage function in a paracrine manner in the ovaries of AOD mice. | Qiuwan Zhang Yating Huang Junyan Sun Tingting Gu Xiaoyan Shao Dongmei Lai | 2019 | Acta Biochimica et Biophysica Sinica2019，51，8： | 14 |
| 4 | Current state and future perspectives of sewer networks in urban China显示文摘中国当局和公众大部分忽略了下水道网络;然而,各种各样的问题与新下水道的增加构造全国正在出现。在中国的下水道网络建设,管理,和维护的当前的国家包括地在这研究被考察。为大约 4.44 亿个人,服务下水道线的 511,200 km 位于城市的区域。在 2014, 70 亿美元在下水道网络建设被投资。然而,下水道扩散率和人均的下水道长度是比在发达国家的那些显著地低的。在本地政府的下水道行政机构是不协调的。法律,规定,和标准是不完全的,并且一些惯例是非科学的。因为下水道腐蚀控制措施没被发射,下水道维护的未来状况是极其冷酷的。而且,检查和康复主要依靠传统的途径。相反,创新技术的全面市场份额由于高费用,资金缺乏,和技术限制是很低的。象班机倒置 cured-in-place 那样的途径尖叫,开车进入用餐的餐厅紫外轻治好的班机,和螺线创伤衬里主要在经济地发达的区域被使用。根据地位和问题分析,瓷器最高的优先级将是以后在下水道网络进行好攻击的维护工作。新技术线路,腐蚀控制 - 周期的设想的检查 - 无沟的康复,能是为在中国的未来下水道维护的最好的选择。为使用这条技术线路的指令和机会在这研究详细被讨论。最后,在在中国的下水道网络的开发的另外的因素被建议。 | Dong Huang Xiuhong Liu Songzhu Jiang Hongchen Wang Junyan Wang Yuankai Zhang | 2018 | Frontiers of Environmental Science & Engineering2018，12，3： | 5 |
| 5 | Exploration and practice of general practitioner responsibility system in an urban community of Shanghai显示文摘Objective:The Minhang district of Shanghai was selected as the subject and its public health management model was investigated.Methods:Minhang became a pilot location for the implementation of the general practitioner responsibility system(GPRS)in 2011.Since then,the management model of public health services in the district has gradually merged with the GPRS through a series of actions:the adjustment of organizations and the coordination mechanism in community public health services,the integration of basic public health services and clinic practice,the establishment of an informationized Internet service platform,comprehensive budgeting management of public health service programs,and performance assessment management of health workers.Results:By the end of 2014,the number of residents who had a contractual relationship with a general practitioner(GP)in Minhang had reached 1.4367 million and all of them had family health records.Compared with 2010,both the rate of maternal management and the rate of children management stayed at high level(≥96%),the rate of hypertension management increased(40.73%vs.28.70%),the rate of blood pressure control increased(82.13%vs.77.51%),the incidence of diabetes decreased(21.93%vs.37.85%),the rate of effective control of blood glucose for dia-betic patients increased(82.43%vs.62.77%),and the rate of child health management increased(99.79%vs.91.54%).Conclusion:The GPRS has helped to create a better community health environment.How-ever,the development of this system is limited by several factors,including the following:the shortage of GPs,most GPs do not have good public health service skills and a correct public health concept,unclear division of different services,and imperfect department coordination. | Yan Wu Yanping Zhao Xiaoxia Huang Junyan Wang Huilin Xu Hualin Su | 2015 | Family Medicine and Community Health2015，3，4： | 5 |
| 6 | Deeply learned broadband encoding stochastic hyperspectral imaging显示文摘Many applications requiring both spectral and spatial information at high resolution benefit from spectral imaging.Although different technical methods have been developed and commercially available,computational spectral cameras represent a compact,lightweight,and inexpensive solution.However,the tradeoff between spatial and spectral resolutions,dominated by the limited data volume and environmental noise,limits the potential of these cameras.In this study,we developed a deeply learned broadband encoding stochastic hyperspectral camera.In particular,using advanced artificial intelligenee in filter design and spectrum reconstruction,we achieved 7000-11,000 times faster signal processing and〜10 times improvement regarding noise toleranee.These improvements enabled us to precisely and dynamically reconstruct the spectra of the entire field of view,previously unreachable with compact computational spectral cameras. | Wenyi Zhang Hongya Song Xin He Longqian Huang Xiyue Zhang Junyan Zheng Weidong Shen Xiang Hao Xu Liu | 2021 | Light(Science & Applications)2021，10，6： | 4 |
| 7 | Mutation of the PHYTOENE DESATURASE 3 gene causes yellowish-white petals in Brassica napus显示文摘Oilseed rape (Brassica napus) with yellow flowers is an attractive ornamental landscape plant during the flowering period,and the development of different petal colors has become a breeding objective.Although yellowish flower color is a common variant observed in field-grown oilseed rape,the genetics behind this variation remains unclear.We obtained a yellowish-white flower (ywf) mutant from Zhongshuang 9 (ZS9) by ethyl methanesulfonate mutagenesis (EMS) treatment.Compared with ZS9,ywf exhibited a lower carotenoid content with a reduced and defective chromoplast ultrastructure in the petals.Genetic analysis revealed that the yellowish-white trait was controlled by a single recessive gene.Using bulked-segregant analysis sequencing (BSA-seq) and kompetitive allele-specific PCR(KASP),we performed map-based cloning of the ywf locus on chromosome A08 and found that ywf harbored a C-to-T substitution in the coding region,resulting in a premature translation termination.YWF,encoding phytoene desaturase 3 (PDS3),was highly expressed in oilseed rape petals and involved in carotenoid biosynthesis.Pathway enrichment analysis of the transcriptome profiles from ZS9 and ywf indicated the carotenoid biosynthesis pathway to be highly enriched.Further analyses of differentially expressed genes and carotenoid components revealed that the truncated Bna A08.PDS3 resulted in decreased carotenoid biosynthesis in the mutant.These results contribute to an understanding of the carotenoid biosynthesis pathway and manipulation of flower-color variation in B.napus. | Chuanji Zhao Luqman Bin Safdar Meili Xie Meijuan Shi Zhixue Dong Li Yang Xiaohui Cheng Yueying Liu Zetao Bai Yang Xiang Chaobo Tong Junyan Huang Lijiang Liu Shengyi Liu | 2021 | The Crop Journal2021，9，5： | 3 |
| 8 | Syntenic quantitative trait loci and genomic divergence for Sclerotinia resistance and ?owering time in Brassica napus显示文摘Oilseed rape(Brassica napus) is an allotetraploid with two subgenomes descended from a common ancestor. Accordingly, its genome contains syntenic regions with many duplicate genes, some of which may have retained their original functions, whereas others may have diverged. Here, we mapped quantitative trait loci(QTL) for stem rot resistance(SRR), a disease caused by the fungus Sclerotinia sclerotiorum, and flowering time(FT) in a recombinant inbred line population. The population was genotyped using B.napus 60 K single nucleotide polymorphism arrays and phenotyped in six(FT) and nine(SSR) experimental conditions or environments. In total, we detected 30 SRR QTL and 22 FT QTL and show that some of the major QTL associated with these two traits were co-localized,suggesting a genetic linkage between them. Two SRR QTL on chromosome A2 and two on chromosome C2 were shown to be syntenic, suggesting the functional conservation of these regions. We used the syntenic properties of the genomic regions to exclude genes for selection candidates responsible for QTL-associated traits. For example, 152 of the 185 genes could be excluded from a syntenic A2–C2 region. These findings will help to elucidate polyploid genomics in future studies, in addition to providing useful information for B. napus breeding programs. | Fengqi Zhang Junyan Huang Minqiang Tang Xiaohui Cheng Yueying Liu Chaobo Tong Jingyin Yu Tehrim Sadia Caihua Dong Lingyan Liu Baojun Tang Jianguo Chen Shengyi Liu | 2019 | Journal of Integrative Plant Biology2019，61，1： | 3 |
| 9 | ^99Tc^m-HYNIC-TOC SPECT/CT显像在胰腺神经内分泌肿瘤患者诊断和随访中的临床应用显示文摘目的确定^99Tc^m-联肼尼克酰胺(HYNIC)-酪氨酸3-奥曲肽(TOC)SPECT/CT显像在疑似神经内分泌肿瘤的胰腺肿块评价及胰腺神经内分泌肿瘤患者随访中的价值。方法回顾性分析了184例行^99Tc^m-HYNIC-TOCSPECT/CT显像的患者。所有患者分为2组,组1评价该显像对胰腺可疑肿块的诊断效能(n=140),组2术后随访是否有复发及转移(n=44)。比较注射显像剂后2h的显像结果与最终病理诊断结果及临床随访结果,随后分析肿瘤与本底的比值(TBR)和肿瘤分级的关系。结果组1中,67.9%(95/140)的患者诊断为神经内分泌肿瘤,包括85例神经内分泌瘤和10例神经内分泌癌。^99Tc^m-HYNIC-TOCSPECT/CT显像诊断神经内分泌肿瘤的灵敏度、特异性和准确性分别为81.1%、84.4%和82.1%。 | 唐军(译) Junyan Xu Yi Li Xiaoping Xu Jiangang Zhang Yingjian Zhang Xianjun Yu Dan Huang | 2018 | 中华核医学与分子影像杂志2018，38，12： | 3 |
| 10 | Plasmacytoid dendritic cell deficiency in neonates enhances allergic airway inflammation via reduced production of IFN-α显示文摘Allergic asthma,a chronic inflammatory airway disease associated with type 2 cytokines,often originates in early life.Immune responses at an early age exhibit a Th2 cell bias,but the precise mechanisms remain elusive.Plasmacytoid dendritic cells(pDCs),which play a regulatory role in allergic asthma,were shown to be deficient in neonatal mice.We report here that this pDC deficiency renders neonatal mice more susceptible to severe allergic airway inflammation than adult mice in an OVA-induced experimental asthma model.Adoptive transfer of pDCs or administration of IFN-αto neonatal mice prevented the development of allergic inflammation in wild type but not in IFNAR1−/−mice.Similarly,adult mice developed more severe allergic inflammation when pDCs were depleted.The protective effects of pDCs were mediated by the pDC-/IFN-α-mediated negative regulation of the secretion of epithelial cell-derived CCL20,GM-CSF,and IL-33,which in turn impaired the recruitment of cDC2 and ILC2 cells to the airway.In asthmatic patients,the percentage of pDCs and the level of IFN-αwere lower in children than in adults.These results indicate that impairment of pDC-epithelial cell crosstalk in neonates is a susceptibility factor for the development of allergeninduced allergic airway inflammation. | Min Wu Liuchuang Gao Miao He Hangyu Liu Han Jiang Ketai Shi Runshi Shang Bing Liu Shan Gao Hebin Chen Feili Gong Erwin WGelfand Yafei Huang Junyan Han | 2020 | Cellular & Molecular Immunology2020，17，5： | 3 |
| 11 | Effects ofβ-alanine on intestinal development and immune performance of weaned piglets显示文摘Beta-alanine is an important amino acid involved in several metabolic reactions in the body.The study aimed to investigate the effect ofβ-alanine supplementation on intestinal development and the immune performance of weaned piglets.Thirty-two 21-day-old healthy weaned piglets(half female and half male;Duroc×Landrace×Yorkshire)with an initial body weight of 8.11±0.21 kg were randomly divided into 4 groups with 8 replicates of 1 pig each.The control group was fed a basal diet and the three experimental treatment groups were fed diets supplemented with 300,600 and 1,200 mg/kgβ-alanine,respectively.The trial lasted 28 days and the diets fed were divided into 2 phases:the late lactation period(day 1 to 14)and the nursery period(day 15 to 28),during which the weaned piglets had free access to food and water.The regulatory effects ofβ-alanine were further investigated in vitro using organoids obtained from the jejunum of piglets.In vivo,the addition ofβ-alanine to the diet had no significant effect on the growth performance of weaned piglets(P>0.05),but significantly reduced serum levels of immunoglobulin G(IgG)(P<0.01),immunoglobulin M(IgM)(P=0.005),and complement 3(C3)(P=0.017).The serum interleukin-6(IL-6)levels(P<0.01)were significantly reduced in the 1,200 mg/kg treatment group.The addition ofβ-alanine increased ileal villus height,with the most significant effect at a concentration of 300 mg/kg(P=0.041).The addition of 600 mg/kgβ-alanine significantly up-regulated the expression of superoxide dismutase(SOD)activity(P=0.020)and the zonula occludens-1(ZO-1)gene(P=0.049)in the jejunum.Diets supplemented with 300 mg/kgβ-alanine significantly increased the number of Ki67 positive cells in the jejunal crypts(P<0.01).In vitro,β-alanine increased the organoid budding rates(P=0.001)and the budding height of the crypt significantly(P=0.004).In conclusion,β-alanine can improve intestinal morphology and barrier function,reduce inflammatory responses and alleviate the adverse effects of weaning stress on piglet intestinal health. | Linlin Chen Yan Zhong Xiangqin Ouyang Chunfeng Wang Lanmei Yin Jing Huang Yali Li Qiye Wang Junyan Xie Pengfei Huang Huansheng Yang Yulong Yin | 2023 | Animal Nutrition2023，，1： | 2 |
| 12 | Properties and Structure of Microcrystal Muscovite Composite Superabsorbent显示文摘Microcrystal muscovite composite superabsorbents(MMCSA) were prepared by water solution polymerization using acrylic acid, acrylamide and itaconic acid as comonomers and microcrystal muscovite as an inorganic additive. Properties, such as water absorbency, salt absorbency, gel strength, water retention capacity and structure of MMCSA characterized by SEM and XRD, were investigated. Water absorbency, salt absorbency, gel strength, water retention capacity and thermostability were enhanced by incorporation of suitable amount of microcrystal muscovite. Water absorption of MMCSA was rapid, requiring 24.55 min to reach 63% of equilibrium absorbency(1218 g/g). Microcrystal muscovite was physically combined into the polymeric network without destroying its polycrystalline structure and microcrystal muscovite composite superabsorbent had some irregular, undulant, and small microporous holes with sheet-like microcrystal muscovite distributed in the polymeric matrix. | 万涛 XIONG Lei HUANG Runqiu SUN Mengmeng QIN Lili TAN Xuemei HU Junyan | 2014 | Journal of Wuhan University of Technology(Materials Science)2014，29，6： | 2 |
| 13 | De novo design of future rapeseed crops:Challenges and opportunities显示文摘To address the global demand for rapeseed while considering farmers’profit,we face the challenges of making a quantum leap in seed yield and,at the same time,reducing yield loss due to biotic and abiotic stresses.We also face the challenge of efficiently applying new transformative biotechnology tools such as gene editing and breeding by genome design to increase rapeseed productivity and profitability.In this Perspective,we review advances in research on the physiological and genetic bases of both stress factorsaffected yield stability and seed yield potential,focusing on source–sink relationships and allocation of photosynthetic assimilates to vegetative growth and seed development.We propose research directions and highlight the role of plant architecture in the relative contributions of the root system,leaves,and pods to seed yield.We call for de novo design of new rapeseed crops.We review trait variation in existing germplasm and biotechnologies available for crop design.Finally,we discuss opportunities to apply fundamental knowledge and key germplasm to rapeseed production and propose an ideotype for de novo design of future rapeseed cultivars. | Shengyi Liu Harsh Raman Yang Xiang Chuanji Zhao Junyan Huang Yuanyuan Zhang | 2022 | The Crop Journal2022，10，3： | 2 |
| 14 | Arabidopsis NIMIN1,2 mediate redox homeostasis and JA/ET pathways to modulate Botrytis cinerea resistance显示文摘Arabidopsis NIM1-INTERACTING1 (NIMIN1) and NIMIN2 are required for salicylic acid (SA)-dependent resistance against biotrophic pathogens. In this study, we have demonstrated that NIMIN1, 2 are also essential for plant defense response to necrotrophic pathogen Botrytis cinerea. The nimin1 and nimin2 mutants displayed a higher susceptibility against B. cinerea than the wild type, which correlated with a decrease in B. cinerea-induced PDF).2 expression. Mutation in NIMIN1 or NIMIN2 enhanced accumulation of hydrogen peroxide (H_2O_2) with reductions in the activities of three main antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), and peroxidase (POD) at the early time (24h) of upon B. cinerea infection. These mutations also resulted in a visible decrease in B.cinerea-induced Ethylene Responsive Factor 1 (ERF1), Octadecanoid-Responsive Arabidopsis AP2/ERF 59 (ORA59), Allene Oxide Cyclase (AOC3), Opda Reductase 3 (OPR3),ACC Synthesis 2 (ACS2) and ACS6 expression, but an advance in MYC2 expression,indicating that NIMIN1,2 are essential for B. cinerea-activated jasmonic acid (JA)/ethylene(ET) biosynthesis and signaling. However, mutation in NIMIN1 or NIMIN2 drastically suppressed JA-, but not ET-activated PDF1.2 expression. Together, these results suggest that NIMIN1,2 may positively control the B. cinerea resistance by mediating redox homeostasis and JA/ET pathways in Arabidopsis. | Dian Wang Junyan Huang Yizhou He Gongke Zhou Shengyi Liu Guohua Chai | 2018 | Oil Crop Science2018，3，1： | 2 |
| 15 | Photo1 properties of YAG: Tb nano - powders under vacuum ultraviolet excitation 显示文摘 | Guifang Li Quanxi Cao Zhimin Li Yunxia Huang Yunge Wei Junyan Shi | 2009 | Journal of Alloys and Compounds2009，485，12： | 1 |
| 16 | Mapping loci controlling fatty acid profiles, oil and protein content by genome-wide association study in Brassica napus显示文摘Optimizing the profile and quantity of fatty acids in rapeseed(Brassica napus L.) is critical for maximizing the value of edible oil and biodiesel. However, selection of these complex seed quality traits is difficult before haplotypes controlling their contents are identified. To efficiently identify genetic loci influencing these traits and underlying candidate genes and networks, we performed a genome-wide association study(GWAS) of eight seed quality traits(oil and protein content, palmitic, stearic, oleic, linoleic, eicosenoic and erucic acids content). The GWAS population comprised 370 diverse accessions, which were phenotyped in five environments and genotyped using 60K SNP arrays. The results indicated that oil and protein contents generally showed negative correlations, while fatty acid contents showed positive or negative correlations,with palmitic and erucic acid contents directly affecting oil content. Seven SNPs on five chromosomes were associated with both seed oil and protein content, and five genes orthologous to genes in Arabidopsis thaliana were predicted as candidates. From resequencing data, besides known haplotypes in Bna A.FAE1.a and Bna C.FAE1.a, three accessions harboring a new haplotype conferring moderate erucic acid content were identified. Interestingly, in a haplotype block, one haplotype was associated with high palmitic acid content and low oil content, while the others showed the reverse effects. This finding was consistent with a negative correlation between palmitic acid and oil contents, suggesting historical selection for high oil content. The identification by this study of genetic variation and complex correlations of eight seed quality traits may be beneficial for crop selection strategies. | Minqiang Tang Yuanyuan Zhang Yueying Liu Chaobo Tong Xiaohui Cheng Wei Zhu Zaiyun Li Junyan Huang Shengyi Liu | 2019 | The Crop Journal2019，7，2： | 1 |
| 17 | Application of a rotation system to oilseed rape and rice fields in Cd-contaminated agri- cultural land to ensure, food safety显示文摘 | Yu Lingling Zhu Junyan Huang Qingqing | 2014 | Ecotoxicology and Environmental Safety2014，108，： | 1 |
| 18 | Fusion bonding and microstructure formation in TiB_(2)-based ceramic/metal composite materials fabricated by combustion synthesis under high gravity显示文摘The novel ceramic/metal composite materials were successfully fabricated by combustion synthesis in high gravity field.In this paper,the Ti-B_(4)C was selected as the main combustion reaction system to obtain TiB_(2)-TiC ceramic substrate,and the 1Cr18Ni9Ti stainless steel was selected as the metal substrate.It was found that the TiB_(2)-TiC/1Cr18Ni9Ti composite materials exhibited continuously graded composition and hybrid microstructure.The TiC1-x carbides and TiB_(2)platelets decreased gradually in size and volume fraction from the ceramic to stainless steel.Due to the rapid action of thermal explosion as well as the dissolution of the molten stainless steel into TiB_(2)-TiC liquid,the diffusion-controlled concentration gradient from the ceramic liquid to the alloy liquid was observed.Finally,as a result of the rapid sequent solidification of the ceramic liquid and the melt alloy surface,the laminated composite materials were achieved in multilevel,scale-span hybrid microstructure. | Xuegang HUANG Jie HUANG Zhongmin ZHAO Long ZHANG Junyan WU | 2015 | Journal of Advanced Ceramics2015，4，2： | 1 |
| 19 | Convenient and efficient access to tri-and tetra-substituted 4-fluoropyridines via a[3+2]/[2+1]cyclization reaction显示文摘A[3+2]/[2+1]cycloaddition reaction of gem–difluorocyclopropenes is presented,offering a mild and efficient approach to accessing tri-and tetra-substituted 4-fluoropyridines in moderate to good yields with excellent regioselectivity.Multiple synthetic applications,including process-scale reactions,modification of bioactive molecules,derivatization reactions and synthesis of the analogue of the PKM2 modulator,are subsequently described. | Xuejiao Tang Kun Liu Zeming Qu Junyan Zhan Rukui Zhu Fan Teng Lili Meng Yanmin Huang Chusheng Huang Yimiao He Qiang Zhu | 2022 | Chinese Chemical Letters2022，33，6： | 1 |
| 20 | Study on the Adhesive for the Production of High Strength Four Layer Composite Corrugated Board显示文摘In order to study of adhesive which is applicable to the production of high strength four layer composite corrugated board,the composite corrugated medium was respectively coated with cassava starch adhesive,environmental-friendly modified water glass binder,CP-88 starch adhesive,polyvinyl alcohol adhesive and polyvinyl acetate adhesive,then the edgewise crush resistance and flat crush resistance contrast experiment on produced corrugated board samples was tested.The experiment results demonstrated that the produced corrugated board with environmental-friendly modified water glass binder had high edgewise crush resistance,general flat crush resistance and more economic,so the environmental-friendly modified water glass binder can be used for the production of high strength four layer composite corrugated board. | Junyan Huang Linlin Yu Huizhong Zhang Jie Ma | 2015 | 材料科学研究(中英文版)2015，4，3： | 0 |
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