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| 1 | Toxicity of the brominated flame retardant tris-(2,3-dibromopropyl) isocyanurate in zebrafish (Danio rerio)显示文摘Tris-(2,3-dibromopropyl) isocyanurate (TBC) is a heterocyclic brominated flame retardant that was recently detected in the environment in China.TBC is semi-volatile and can accumulate in the lipid of some species,but little is known about its effect on aquatic organisms.We exposed adult zebrafish to 0,0.25,1 and 4mg/L TBC for 28 d and measured the effect on survival,growth,histopathology,hormone levels,enzyme activity,and gene expression.TBC exposure had no effect on survival or growth.We observed significant damage to the liver and gill,including hepatocellular swelling and fatty degeneration in the liver as well as proliferation and edema of epithelial cells in the gills.In addition,exposure to 4mg/L TBC induced proliferation of goblet cells in the intestine of both sexes,acellular areas in the testis,and thinly scattered vitellogenic granules in vitellogenic oocytes.TBC exposure had no effect on the levels of thyroid hormones,testosterone,estradiol,liver superoxide dismutase activity,malondialdehyde content,and brain cholinesterase activity.By contrast,hepatic vitellogenin and cytochrome P4501A gene expression was significantly down-regulated in both male and female zebrafish in response to TBC exposure.Our results suggest that exposure to TBC causes a variety of potential reproductive and endocrine toxic effects. | ZHANG Xu LI Juan CHEN MinJie WU Le ZHANG Chi ZHANG Jie ZHOU QunFang LIANG Yong | 2011 | Chinese Science Bulletin2011，56，15： | 13 |
| 2 | nterferon alpha (IFNα)-induced TRIM22 interrupts HCV 'eplication by ubiquitinating NS5A显示文摘 | Chen Yang Xinhao Zhao Dakang Sun Leilei Yang Chang Chong Yu Pan Xiumei Chi Yanhang Gao Moli Wang Xiaodong Shi Haibo Sun Juan Lv Yuanda Gao Jin Zhong Junqi Niu Bing Sun | 2016 | Cellular & Molecular Immunology2016，13，1： | 13 |
| 3 | Preparation of magnetically separable mesoporous activated carbons from brown coal with Fe3O4显示文摘Magnetically separable mesoporous activated carbon was prepared from brown coal in the presence of Fe3O4 as a bi-functional additive.Magnetic activated carbon(MAC)was characterized by lowtemperature nitrogen adsorption,scanning electron microscopy(SEM),transmission electron microscopy(TEM),X-ray diffraction(XRD),X-ray photoelectron spectroscopy(XPS)and vibrating sample magnetometry(VSM).The evolution behaviors and transition mechanism of Fe3O4 during the preparation of MAC were investigated.The results show that prepared MAC with 6 wt%Fe3O4 addition having a specific surface area and mesopore ratio of 370 m^2·g^-1 and 55.7%,which meet the requirements of adsorption application and magnetic recovery.Highly dispersed iron-containing aggregates with the size of 0.1 lm in the MAC were observed.During the preparation of MAC,Fe3O4 could enhance the escape of volatiles during the carbonization.Fe3O4 could also accelerate burning off the carbon wall during activation,which leads to enlarging micropore size,then resulting in the generation of mesopore and macropore.As a result,a part of Fe3O4 converted into FeO,FeOOH,a-Fe,c-Fe,Fe2SiO4 and compound of Aluminum-iron-silicon.The prepared activated carbon,which was magnetized by both of residual Fe3O4,reduced a-Fe and c-Fe,can be easily separated from the original solution by external magnetic field. | Yong Jiang Qiang Xie Yanhai Zhang Cuiyu Geng Bin Yu Juan Chi | 2019 | International Journal of Mining Science and Technology2019，29，3： | 8 |
| 4 | Ultrathin Co(Ni)-doped MoS2 nanosheets as catalytic promoters enabling efficient solar hydrogen production显示文摘收获太阳能经由水减小驾驶氢进化反应的有效人工的光合的系统的设计从两个是很重要的理论、实际的观点。与吸收材料的大光集成适当合作催化剂倡导者代表理想的策略在氢生产提高太阳能的变换效率。此处,第一次,我们报导由 ultrathin 公司(Ni ) 组成的唯一的混合结构的一个班的合成做了瞬间 2 nanosheets (合作催化剂倡导者) 在半导体 CdS nanorods (轻吸收器) 上亲密地成年。同样综合的一个维的 CdS@doped 瞬间 2 heterostructures 展出了很高的 photocatalytic 活动(与 17.3% 的量收益) 并且向从水的光致还原的 H 2 进化的稳定性。理论计算表明做的 Ni 能在瞬间 2 nanosheets 的边地点增加不协调的原子的数字越过 CdS/MoS 2 接口以及氢减小支持电子转移,导致有效 H 2 进化反应。 | Xiaoyan Ma Jinquan Li Changhua An Juan Feng Yuhua Chi Junxue Liu Jun Zhang Yugang Sun | 2016 | Nano Research2016，9，8： | 7 |
| 5 | Integrin-interacting protein Kindlin-2 induces mammary tumors in transgenic mice显示文摘Kindlin-2, an integrin-interacting protein, regulates breast cancer progression. However, currently, no animal model to study the role of Kindlin-2 in the carcinogenesis of mammary gland is available. We established a Kindlin-2 transgenic mouse model using a mammary gland-specific promoter, mammary tumor virus(MMTV) long terminal repeat(LTR). Kindlin-2 was overexpressed in the epithelial cells of the transgenic mice. The mammary gland ductal trees were found to grow faster in MMTV-Kindlin-2 transgenic mice than in control mice during puberty. Kindlin-2 promoted mammary gland growth as indicated by more numerous duct branches and larger lumens, and more alveoli were formed in the mammary glands during pregnancy under Kindlin-2 overexpression. Importantly, mammary gland-specific expression of Kindlin-2 induced tumor formation at the age of 55 weeks on average. Additionally, the levels of estrogen receptor and progesterone receptor were decreased, whereas human epidermal growth factor receptor 2 and β-catenin were upregulated in the Kindlin-2-induced mammary tumors. These findings demonstrated that Kindlin-2 induces mammary tumor formation via activation of the Wnt signaling pathway. | Bing Li Xiaochun Chi Jiagui Song Yan Tang Juan Du Xiaokun He Xiaoran Sun Zhenwu Bi Yunling Wang Jun Zhan Hongquan Zhang | 2019 | Science China(Life Sciences)2019，62，2： | 6 |
| 6 | Study on the spectral response of Brassica Campestris L. leaf to the copper pollution显示文摘Brassica Campestis L. was cultivated in the soil at the laboratory. The red edge,the visual spectrum and the near-infrared spectrum of Brassica Campestis L. leaf were used to explore the spectral response of Brassica Campestis L. leaf to the copper stress. As the Cu content in the soil gets increased,the copper level in Brassica Campestris L. leaf would be increased,and the chlorophyll level in Brassica Campestris L. leaf would be decreased. As a result,the visual spectral reflectance (A1) of Brassica Campestris L. leaf is increased,and the blue-shift (moving towards the shorter waveband) degree (S) of the red edge (the ascending region of the re-flectivity at 680―740 nm) gets increased. However,the near-infrared spectral re-flectance (A2) decreases. With the correlation coefficient R2 more than 0.95,these parameters of A1,A2 and S can be perfectly used to simulate and predict the copper level in Brassica Campestris L. leaf. | LIU SuHong LIU XinHui HOU Juan CHI GuangYu CUI BaoShan | 2008 | Science China(Technological Sciences)2008，51，2： | 5 |
| 7 | Control of T H 17/T reg Balance by Hypoxia-Inducible Factor 1显示文摘 | Eric V. Dang Joseph Barbi Huang-Yu Yang Dilini Jinasena Hong Yu Ying Zheng Zachary Bordman Juan Fu Young Kim Hung-Rong Yen Weibo Luo Karen Zeller Larissa Shimoda Suzanne L. Topalian Gregg L. Semenza Chi V. Dang Drew M. Pardoll Fan Pan | 2011 | Cell2011，，5： | 3 |
| 8 | A new springback compensation method for sheet metal bending based on curvature correction显示文摘 | LIAO Juan ZHOU Chi | 2010 | Advanced Materials Research2010，，： | 1 |
| 9 | Trehalose accu-mulation from soluble starch by Saccharomy-copsis fibuligerasdu显示文摘 | CHI Zhenming LIU Juan ZHANG Wei | 2001 | Enzyme and Microbial Technology2001，28，23： | 1 |
| 10 | Characterization of the biologic activities of a recombinant human zona pellucida protein 3 expressed in human ovarian teratocarcinoma (PA-1) cells显示文摘 | DONG K W CHI T F JUAN Y W | 2001 | Am J Obstet Gynecol2001，184，5： | 1 |
| 11 | Polymer Waveguide Coupled Surface Plasmon Refractive Index Sensor:A Theoretical Study显示文摘A waveguide coupled surface plasmon sensor for detection of liquid with high refractive index(RI)is designed based on polymer materials.The effects of variation of the thickness of the Au film,polymethyl methacrylate(PMMA)buffer,and waveguide layer on the sensing performance of the waveguide are comprehensively investigated by using the finite difference method.Numerical simulations show that a thinner gold film gives rise to a more sensitive structure,while the variation of the thickness of the PMMA buffer and waveguide layer has a little effect on the sensitivity.For liquid with high RI,the sensitivity of the sensor increases significantly.When RI of liquid to be measured increases from 1.45 to 1.52,the sensitivity is as high as 4518.14 nm/RIU,and a high figure of merit of 114.07 is obtained.The waveguide coupled surface plasmon RI sensor shows potential applications in the fields of environment,industry,and agriculture sensing with the merits of compact size,low cost,and high integration density. | Lanting JI Shuqing YANG Rongna SHI Yujie FU Juan SU Chi WU | 2020 | Photonic Sensors2020，10，4： | 1 |
| 12 | Antiviral Treatment Alters the Frequency of Activating and Inhibitory Receptor-Expressing Natural Killer Cells in Chronic Hepatitis B Virus Infected Patients显示文摘 | Juan Lv Qinglong Jin Haibo Sun Xiumei Chi Xiaoli Hu Hongqing Yan Yu Pan Weihua Xiao Zhigang Tian Jinlin Hou Damo Xu Zhengkun Tu Junqi Niu Alex Kleinjan | 2012 | Mediators of Inflammation2012，，： | 1 |
| 13 | A Study of Micro V-Groove Fabrication in Ultra-Precision Freeform Machining显示文摘 | To Sandy Cheung Chi Fai Wang Su Juan Lee Wing Bun | 2007 | Key Engineering Materials2007，，339： | 1 |
| 14 | Dwarf apple MbDREB 1 enhances plant tolerance to low temperature, drought, and salt stress via both ABA-dependent and ABA-independent pathways 显示文摘 | YANG WEI LIU XIAO DAN CHI XIAO JUAN | 2011 | Planta2011，233，2： | 1 |
| 15 | Realization of Perfect Teleportation with W-States in Cavity QED显示文摘We put forward an experimentally feasible protocol for realizing a perfect teleportation by using a class of W-state in QED.The simple way of generating the entangled channel and distinguishing the measurement bases is the distinct feature of our scheme.In addition,the probability of teleportation is up to 100%.The scheme can be implemented by the present cavity QED techniques. | HE Juan YE Liu MA Chi LIU Qi NI Zhi-Xiang | 2008 | Communications in Theoretical Physics2008，49，3： | 1 |
| 16 | Characterization of the biologic activities of a recombinant human zona pellucida protein 3expressed in human ovarian teratocarcinoma ( PA-1 ) cells 显示文摘 | Dong KW Chi TF Juan YW | 2001 | Am J Obstet Gynecol2001，184，5： | 1 |
| 17 | Identification of Internal Ribosomal Entry Site inside Open Reading Frame of 14-3-3β Gene显示文摘Prion diseases are characterized by neurodegeneration and protein aggregation,which are caused by the accumulation of a misfolded and protease-resistant form of the cellular prion protein.Several studies suggest that the accumulation of a misfolded alternate cellular protein disturbs quality control mechanisms,leading to endoplasmic reticulum(ER)stress involved in prion diseases[1-3].Prion infection activates the splicing of the unfolded protein response transcription factor XBP-1.Misfolded mutant PrP associated with inherited. | SONG Qin Qin LUO Xiao Nuan CHI Miao Miao SONG Juan XIA Dong HAN Jun | 2020 | Biomedical and Environmental Sciences2020，33，4： | 1 |
| 18 | Circulating Dickkof-1 as a potential biomarker associated with the prognosis of patients with rheumatoid arthritis-associated interstitial lung disease显示文摘To the Editor:Interstitial lung disease(ILD)is a common extra-articular manifestation in patients with connective tissue diseases(CTDs),including rheumatoid arthritis(RA),which contributes significantly to the disease burden and excess mortality.[1]It has been well-recognized that RA-associated ILD(RA-ILD)patients have a threefold higher risk of death than RA patients without ILD.[2]However,among approximately 30%of ILD patients,the specific diagnosis cannot be made from clinical findings and high-resolution computed tomography features,resulting in diagnostic and management uncertainty. | Jing Xue Yu-Jiao Wang He-Chun Xia Xue-Yun Liang Jie-Da Cui Min Yu Xiao-Ming Liu Shu-Hong Chi Juan Chen | 2021 | Chinese Medical Journal2021，，9： | 1 |
| 19 | Nuclear penetrtion of surface functionlized gold nanopartieles 显示文摘 | Yan- Juan Gu Jinping Cheng Chun- Chi Lin | 2009 | Toxicology and Applied Pharmeology2009，237，2： | 1 |
| 20 | Theoretical Study of La , Ca modified and Pure PbTiO_3 Nanocrystals显示文摘Quantum chemistry calculations of La , Ca modified and pure PbTiO\-3 nanocrystals were carried out by means of the cluster model in DFT DVM calculating program on which the regularity of the charge distribution was drawn. The analysis of the density of state(DOS) showed that when the cubic phase PbTiO 3 nanocrystal is changed into tetragonal phase, the interaction among Ti 3d , O 2p , and Pb 6p atomic orbitals causes the dipole moment and spontaneous polarization on the axis of the crystal, which resulted in the appearance of ferroelectric phase. At the same time, the dipole moment and the intensity of the spontaneous polarization were calculated as well. | FU Hong gang a,b * , YU Hai tao b , ZHANG Zhi qian a , MIN Xin min c LU GUO ming b and CHI Yu juan b (Department of Applied Chemistry, Harbin institute of technology a, Harbin 150001, P.R. China College of Ch | 1999 | Chemical Research in Chinese Universities1999，15，4： | 1 |
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