|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Model combining pre-transplant tumor biomarkers and tumor size shows more utility in predicting hepatocellular carcinoma recurrence and survival than the BALAD models显示文摘AIM To assess the performance of BALAD, BALAD-2 and their component biomarkers in predicting outcome of hepatocellular carcinoma(HCC) patients after liver transplant.METHODS BALAD score and BALAD-2 class are derived from bilirubin, albumin, alpha-fetoprotein(AFP), Lens culinaris agglutinin-reactive AFP(AFP-L3), and des-gammacarboxyprothrombin(DCP). Pre-transplant AFP, AFP-L3 and DCP were measured in 113 patients transplanted for HCC from 2000 to 2008. Hazard ratios(HR) for recurrence and death were calculated. Univariate and multivariate regression analyses were conducted. C-statistics were used to compare biomarker-based to predictive models. RESULTS During a median follow-up of 12.2 years, 38 patients recurred and 87 died. The HRs for recurrence in patients with elevated AFP, AFP-L3, and DCP defined by BALAD cut-off values were 2.42(1.18-5.00), 1.86(0.98-3.52), and 2.83(1.42-5.61), respectively. For BALAD, the HRs for recurrence and death per unit increased score were 1.48(1.15-1.91) and 1.59(1.28-1.97). For BALAD-2, the HRs for recurrence and death per unit increased class were 1.45(1.06-1.98) and 1.38(1.09-1.76). For recurrence prediction, the combination of three biomarkers had the highest c-statistic of 0.66 vs. 0.64, 0.61, 0.53, and 0.53 for BALAD, BALAD-2, Milan, and UCSF, respectively. Similarly, for death prediction, the combination of three biomarkers had the highest c-statistic of 0.66 vs 0.65,0.61, 0.52, and 0.50 for BALAD, BALAD-2, Milan, and UCSF. A new model combining biomarkers with tumor size at the time of transplant(S-LAD) demonstrated the highest predictive capability with c-statistics of 0.71 and 0.69 for recurrence and death. CONCLUSION BALAD and BALAD-2 are valid in transplant HCC patients, but less predictive than the three biomarkers in combination or the three biomarkers in combination with maximal tumor diameter(S-LAD). | Nicha Wongjarupong Gabriela M Negron-Ocasio Roongruedee Chaiteerakij Benyam D Addissie Essa A Mohamed Kristin C Mara William S Harmsen J Paul Theobald Brian E Peters Joseph G Balsanek Melissa M Ward Nasra H Giama Sudhakar K Venkatesh Denise M Harnois Michael R Charlton Hiroyuki Yamada Alicia Algeciras-Schimnich Melissa R Snyder Terry M Therneau Lewis R Roberts | 2018 | World Journal of Gastroenterology2018，24，12： | 5 |
| 2 | 光动力疗法治疗非小细胞肺癌显示文摘光动力疗法被越来越多地应用于治疗胸部恶性肿瘤。对于早期非小细胞肺癌(如支气管腔内肺癌)、X线检查阴性或同时性原发癌,光动疗法可作为主要治疗手段进行腔内根治性治疗。作为单一根治疗法,光动力疗法是治疗支气管镜可见≤1 cm且无软骨外浸润的肺部肿瘤的最有效方法。对于晚期非小细胞癌患者,光动力治疗可以作为综合根治疗法的一部分,用于减轻阻塞性支气管内病变,增加可手术性或缩小所需手术范围。本文对现有发表的应用光动力疗法治疗至少10例以上非小细胞肺癌病例的研究文献进行综述,提出了光动力疗法应用的治疗建议并进行了总结。 | Charles B Simone II Joseph S Friedberg Eli Glatstein James P Stevenson Daniel H Sterman Stephen M Hahn Keith A Cengel 袁光金 李金銮 朱宇熹 凌扬 | 2013 | 国际病理科学与临床杂志2013，33，3： | 3 |
| 3 | Leptospirosis: a zoonotic disease of global importance显示文摘 | Ajay R Bharti Jarlath E Nally Jessica N Ricaldi Michael A Matthias Monica M Diaz Michael A Lovett Paul N Levett Robert H Gilman Michael R Willig Eduardo Gotuzzo Joseph M Vinetz | 2003 | The Lancet Infectious Diseases2003，，12： | 2 |
| 4 | Classification of remote sensing Images having high spectral resolution显示文摘 | P H Joseph A L David | 1996 | Remote Sensing Environment1996，57，3： | 1 |
| 5 | 查看详情显示文摘 | T H Douglas A C Joseph | | 0，，： | 1 |
| 6 | 循证医学 误用漏斗图的案例分析显示文摘本文要点应该使用严格的标准对循证医学中使用的方法进行评价用于检验发表偏倚的漏斗图在系统性文献综述中应用广泛漏斗图的不对称性,无论是直观上看到的或统计学检验发现的。 | Joseph Lau John P A Ioannidis Norma Terrin Christopher H Schmid Ingram Olkin 谢朝晖 | 2007 | 英国医学杂志中文版2007，10，3： | 1 |
| 7 | The social endocrinology of dominance: Basal testosterone predicts cortisol changes and behavior following victory and defeat显示文摘 | MEHTA P H JONES A C JOSEPHS R A | 2008 | Journal of Personality & Social Psychology2008，，94： | 1 |
| 8 | An Octahedral Template Based on a New Molecular Turn:Synthesis and Structure of a Model Complex and a Reactive,Diphenolic Ligand and Its Metal Complexes显示文摘 | Andrew L V Nathaniel W A Joseph A H | 1998 | Inorg Chem1998，37，： | 1 |
| 9 | An empirical analysis of designchoices in neighborhood-based collaborative filtering algo-rithms显示文摘 | Jon H Joseph A K John R | 2002 | Information Retrieval2002，5，： | 1 |
| 10 | Annual Energy Out- look 2012, DOE/EIA-0383 显示文摘 | John J C Paul D H Joseph A B | 2012 | Energy Information Admin- istration2012，6，： | 1 |
| 11 | Expression of scatter factor in human bladder carcinoma 显示文摘 | JOSEPH A WEISS G H JIN L | 1995 | J Natl Cancer Inst1995，87，5： | 1 |
| 12 | Fate of fructo-oligosaccharides in the human intestine显示文摘 | Martine S A Joseph G A J H Fokko M N | | 0，，02： | 1 |
| 13 | Atrazine and Cancer Incidence Among Pesticide Applicators in the Agricultural Health Study (1994-2007)显示文摘 | Beane Freeman Laura E Rusiecki Jennifer A Hoppin Jane A Lubin Jay H Koutros Stella Andreotti Gabriella Zahm Sheila Hoar Hines Cynthia J Coble Joseph B Barone-Adesi Francesco Sloan Jennifer Sandler Dale P Blair Aaron Alavanja Michael C R | 2011 | Environmental Health Perspectives2011，，9： | 1 |
| 14 | Pre-weaning non-handling of rats disrupts latent inhibition in males, and results in persisting sex- and area-dependent increases in dopamine and serotonin turnover显示文摘 | PETERS S L GRAY J A JOSEPH M H | 1991 | Behav Pharma- col1991，2，3： | 1 |
| 15 | Development of human protein reference database as an initial platform for approaching systems biology in humans 显示文摘 | PERI S NAVARRO J D AMANCHY R KRISTIANSEN T Z JONNALAGADDA C K SURENDRANATH V NIRAN JAN V MUTHUSAMY B GANDHI T K GRONBORG M IBARROLA N DESHPANDE N SHANKER K SHIVASHANKAR H N RASHMI B P RAMYA M A ZHAO Z CHANDRIKA K N PADMA N HARSHA H C YATISH A J KAVITHA M P MENEZES M CHOUDHURY D R SURESH S GHOSH N SARAVANA R CHANDRAN S KRISHNA S JoY M ANAND S K MADAVAN V JOSEPH A WONG G W SCHIEMANN W P CONSTANTINESCU S N HUANG L KHOSRAVI-FAR R STEEN H TEWARI M GHAFFARI S BLOBE G C DANG C V GARCIA J G PEVSNER J JENSEN O N ROEPSTORFF P DESHPANDE K S CHINNAIYAN A M HAMOSH A CHAKRAVARTI A PANDEY A | 2003 | Genome Research2003，13，10： | 1 |
| 16 | Simulation on die filling in gravity die casting using SPH and MAGMASOFT显示文摘 | JOSEPH H PAUL C VLADIMIR A | 1999 | CRC for Alloy and Solidification Technology(CAST)1999，12，68： | 1 |
| 17 | A three-year experiment confirms continuous immobilization of cadmium and lead in contaminatedpaddy field with biochar amendment显示文摘 | Bian R Joseph S Cui L Pan G Li L Liu X Zhang A Rutlidge H Wong S Chia C Marjo C Gong B Munroe P Donne S | 2014 | Journal of Hazardous Materials2014，272，： | 1 |
| 18 | Influence of genotype and environment on isoflavone contents of soybean显示文摘 | Joseph A H Walter R F Patricia A M | 2000 | Crop Sciences2000，40，： | 1 |
| 19 | Virtual facility layout design:the value of an interactive three-dimensional representation显示文摘 | Robert P S Joseph A H | 1999 | International Journal of Production Research1999，37，17： | 1 |
| 20 | The role of technology in sustaining agriculture and the environment显示文摘 | JOSEPH E A JAMES H UTPAL V | 1998 | Ecological Eco- nomics1998，，26： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员