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| 1 | Long-term irritable bowel syndrome symptom control with reintroduction of selected FODMAPs显示文摘AIM To investigate the long-term effect of dietary education on a low fermentable oligosaccharide, disaccharide and polyol(FODMAP) diet on irritable bowel syndrome(IBS) symptoms and quality of life(Qo L).METHODS Participants with IBS(Rome III) were randomized to two groups. Group I commenced a low FODMAP diet at baseline. At three months, group II, so far a comparator group, crossed over to a low FODMAP diet while group I started re-challenging foods. All patients completed the IBS SSS(IBS symptom severity scoring system, 0-500 points increasing with severity), IBS Qo L questionnaire(0-100 increasing with Qo L), a FODMAP specific food frequency questionnaire and provided a stool sample at baseline, three and six months for microbiome analysis.RESULTS Fifty participants were enrolled into group I(n = 23) or group II(n = 27). Participants in both groups were similar in baseline values but with more men in group I. There was a significantly lower IBS SSS(275.6 ± 63.6 to 128.8 ± 82.5 vs 246.8 ± 71.1 to 203.6 ± 70.1)(P < 0.0002) and increased Qo L(68.5 ± 18.0 to 83 ± 13.4 vs 72.9 ± 12.8 to 73.3 ± 14.4)(P < 0.0001) in group I vs group II at 3 mo. The reduced IBS SSS was sustained at 6 mo in group I(160 ± 102) and replicated in group II(124 ± 76). Fiber intake decreased on the low FODMAP diet(33 ± 17 g/d to 21 ± 8 g/d)(P < 0.01) and after re-introducing FODMAP containing foods increased again to 27 ± 9 g/d. There was no change seen in the intestinal microbiome when participants adopted a low FODMAP diet.CONCLUSION This study demonstrated that a reduction in FODMAPs improves symptoms in IBS and this improvement can be maintained while reintroducing FODMAPs. | Ruth M Harvie Alexandra W Chisholm Jordan E Bisanz Jeremy P Burton Peter Herbison Kim Schultz Michael Schultz | 2017 | World Journal of Gastroenterology2017，23，25： | 5 |
| 2 | Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、 | Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg | 2017 | 现代生物医学进展2017，17，27： | 3 |
| 3 | Failure modes in plasma-sprayed thermal barrier coatings显示文摘 | Schlichting K W Padture N P Jordan E H | 2003 | Mater Sci Eng2003，342，： | 2 |
| 4 | Neurologic disease in wapiti naturally infected with meningeal worm显示文摘 | Carpenter J W Jordan H E Ward B C | 1973 | J Wildl Dis1973，9，： | 1 |
| 5 | Obstructive sleep apne- a: Plasma endothelin-1 precursor but not endothelin-1 levels are elevated and decline with nasal continuous positive airway pressure 显示文摘 | Jordan W Reinbacher A Cohrs S | 2005 | Peptides2005，26，： | 1 |
| 6 | Review article: anatomic double-bundle anterior cruciate ligament reconstruction 显示文摘 | Shen W Jordan S Fu F | 2012 | J OrthopSurg2012，，： | 1 |
| 7 | Breeding crop varieties for stress envi- ronments显示文摘 | Blum A Jordan W R | 1985 | Critical Reviews in Plant Sciences1985，，19： | 1 |
| 8 | CPAP therapy effectively lowers serum homocysteine in obstrucive sleep apnea syndrome显示文摘 | Jordan W Berger C Cohrsl S | 2004 | Neural Transm2004，111，6： | 1 |
| 9 | Rapid and specific detection of Listeria monocytogenes in smoked salmon with BAX-PCR显示文摘 | BECKER B JORDAN S HOLZAPF W H | 2005 | Food Control2005，16，8： | 1 |
| 10 | Chained cross-training of assembly line workers显示文摘 | Inman R R Jordan W C Blumenfeld D E | 2004 | International Journal of Production Research2004，42，10： | 1 |
| 11 | The CO2/O2 specificity of fibulose-1, 5-bisphosphate carboxylase/oxygenase显示文摘 | JORDAN D B OGREN W L | 1984 | Planta1984，41，： | 1 |
| 12 | Detection of channel catfish virus DNA in latently infected catfish显示文摘 | GRAY W L WILLIAMS R J JORDAN R L | 1999 | J Gen Virol1999，80，： | 1 |
| 13 | A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations 显示文摘 | Mathews W Jordan CT Wiegand GW | 1991 | Cell1991，65，： | 1 |
| 14 | Failure modes in plasma sprayed thermal barrier coatings显示文摘 | Schlichting K W Padture N P Jordan E H | 2003 | Mater Sci Eng A2003，342，3： | 1 |
| 15 | Failure modes in plasma-sprayed thermal barriercoatings显示文摘 | Schlichting K W Padture N P Jordan E H etal | 2003 | Materials Science and Engineering2003，，342： | 1 |
| 16 | Changes in strawberry fruit quality during ripening on and off the plant显示文摘 | FORNEY C F KALT W JORDAN M A | 1998 | Acta Horticulturae1998，464，： | 1 |
| 17 | Growth, water rela- tions, and accumulation of organic and inorganic solutes in roots of maize seedlings during salt stress显示文摘 | Rodriguez H G Roberts J K M Jordan W R | 1997 | Plant Physiol1997，113，3： | 1 |
| 18 | Effects of Cere-brovascu- lar challenges on plasma endothelin 显示文摘 | Jordan W Decker M Kamrowski H | 2002 | Neurosci Res2002，43，2： | 1 |
| 19 | In limitations to efficient water use in crop production显示文摘 | Taylor H Jordan W Sinclair T | | 0，，： | 1 |
| 20 | Promising cytotoxic activ-ity profile of fermented wheat germ extract (Avemar (R显示文摘 | Mueller T Jordan K Voigt W | | 0，，： | 1 |
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