|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Incidence and risk factors for early renal dysfunction after liver transplantation显示文摘AIM: To determine renal dysfunction post liver transplantation, its incidence and risk factors in patients from a Belgian University Hospital.METHODS: Orthotopic liver transplantations performed from January 2006 until September 2012 were retrospectively reviewed(n = 187). Patients with no renal replacement therapy(RRT) before transplantation were classified into four groups according to their highest creatinine plasma level during the first postoperative week. The first group had a peak creatinine level below 12 mg/L, the second group between 12 and 20 mg/L, the third group between 20 and 35 mg/L, and the fourth above 35 mg/L. In addition, patients who needed RRT during the first week after transplantation were also classified into the fourth group. Perioperative parameters were recorded as risk factors, namely age, sex, bodymass index(BMI), length of preoperative hospital stay, prior bacterial infection within one month, preoperative ascites, preoperative treatment with β-blocker, angiotensin-converting enzyme inhibitor or non steroidal anti-inflammatory drugs, preoperative creatinine and bilirubin levels, donor status(cardiac death or brain death), postoperative lactate level, need for intraoperative vasopressive drugs, surgical revision, mechanical ventilation for more than 24 h, postoperative bilirubin and transaminase peak levels, postoperative hemoglobin level, amount of perioperative blood transfusions and type of immunosuppression. Univariate and multivariate analysis were performed using logistic ordinal regression method. Post hoc analysis of the hemostatic agent used was also done.RESULTS: There were 78 patients in group 1(41.7%), 46 in group 2(24.6%), 38 in group 3(20.3%) and 25 in group 4(13.4%). Twenty patients required RRT: 13(7%) during the first week after transplantation. Using univariate analysis, the severity of renal dysfunction was correlated with presence of ascites and prior bacterial infection, preoperative bilirubin, urea and creatinine level, need for surgical revision, use of vasopressor, postoperative mechanical ventilation, postoperative bilirubin and urea, aspartate aminotransferase(ASAT), and hemoglobin levels and the need for transfusion. The multivariate analysis showed that BMI(OR = 1.1, P = 0.004), preoperative creatinine level(OR = 11.1, P < 0.0001), use of vasopressor(OR = 3.31, P = 0.0002), maximal postoperative bilirubin level(OR = 1.44, P = 0.044) and minimal postoperative hemoglobin level(OR = 0.059, P = 0.0005) were independent predictors of early post-liver transplantation renal dysfunction. Neither donor status nor ASAT levels had significant impact on early postoperative renal dysfunction in multivariate analysis. Absence of renal dysfunction(group 1) was also predicted by the intraoperative hemostatic agent used, independently of the extent of bleeding and of the preoperative creatinine level.CONCLUSION: More than half of receivers experienced some degree of early renal dysfunction after liver transplantation. Main predictors were preoperative renal dysfunction, postoperative anemia and vasopressor requirement. | Patricia Wiesen Paul B Massion Jean Joris Olivier Detry Pierre Damas | 2016 | World Journal of Transplantation2016，6，1： | 9 |
| 2 | Early plasmapheresis and rituximab for acute humoral rejection after ABO-compatible liver transplantation显示文摘Acute humoral rejection (AHR) is uncommon after ABO-compatible liver transplantation. Herein, we report two cases of AHR treated with plasmapheresis and rituximab in two ABO-compatible liver-transplant patients with preformed anti-human leukocyte antigen donor-specif ic antibodies. Patient 1 experienced a biopsy-proven AHR at day 10 post-transplant. She was treated by steroid pulses, and OKT3. Because of persisting signs of biopsy-proven AHR at day 26, she was treated by plasmapheresis and rituximab. Liver enzyme levels did not improve, and she died on day 41. Patient 2 experienced a biopsy-proven AHR on day 10 post-transplant. She was treated by steroid pulses, plasmapheresis, and rituximab. Liver enzymes returned to within normal range 18 d after diagnosis. Liver biopsies, at 3 and 9 mo post-transplant, showed complete resolution of AHR. We conclude that plasmapheresis should be started as soon as AHR is diagnosed, and be associated with a B-cell depleting agent. Rituximab may be considered as a first-line therapy. | Nassim Kamar Laurence Lavayssière Fabrice Muscari Janick Selves Céline Guilbeau-Frugier Isabelle Cardeau Laure Esposito Olivier Cointault Marie Béatrice Nogier Jean Marie Peron Philippe Otal Marylise Fort Lionel Rostaing | 2009 | World Journal of Gastroenterology2009，15，27： | 6 |
| 3 | Cyclin A2:At the crossroads of cell cycle and cell invasion显示文摘Cyclin A2 is an essential regulator of the cell division cycle through the activation of kinases that participate to the regulation of S phase as well as the mitotic entry. However,whereas its degradation by the proteasome in mid mitosis was thought to be essential for mitosis to proceed,recent observations show that a small fraction of cyclin A2 persists beyond metaphase and is degraded by autophagy. Its implication in the control of cytoskeletal dynamics and cell movement has unveiled its role in the modulation of Rho A activity. Since this GTPase is involved in both cell rounding early in mitosis and later,in the formation of the cleavage furrow,this suggests that cyclin A2 is a novel actor in cytokinesis. Taken together,these data point to this cyclin as a potential mediator of cell-niche interactions whose dysregulation could be taken as a hallmark of metastasis. | Abdelhalim Loukil Caroline T Cheung Nawal Bendris Bénédicte Lemmers Marion Peter Jean Marie Blanchard | 2015 | World Journal of Biological Chemistry2015，6，4： | 6 |
| 4 | Maintenance infliximab for Crohn’s disease: the ACCENT I randomised trial显示文摘 | Stephen B Hanauer Brian G Feagan Gary R Lichtenstein Lloyd F Mayer S Schreiber Jean Frederic Colombel Daniel Rachmilewitz Douglas C Wolf Allan Olson Weihang Bao Paul Rutgeerts | 2002 | The Lancet2002，，9317： | 6 |
| 5 | 焦虑抑郁对慢性阻塞性肺疾病急性加重和住院的影响显示文摘本研究旨在通过为期1年的多中心、前瞻性随访评价焦虑抑郁作为独立危险因素对慢性阻塞性肺疾病急性加重和住院的影响。研究随机选取来自北京10所综合医院的491例稳定期COPD患者,所有患者进入研究前均签署知情同意书。研究持续1年,开始及结束时进行现场问卷调查,记录患者的个人资料、1年前COPD急性加重发作次数和住院次数等。应用认证的中文版焦虑一抑郁量表(HADS)评价焦虑、抑郁状态;应用5级医学研究呼吸困难评分法(MRCQ)评价呼吸困难; | 徐婉宁 Jean PC Stanley S 林英翔 杨汀 Robert P 王辰 Jean B | 2010 | 中华结核和呼吸杂志2010，33，5： | 4 |
| 6 | Role of proton pump inhibitors in the occurrence and the prognosis of spontaneous bacterial peritonitis in cirrhotic patients with ascites显示文摘 | Marie Vos Bénédicte Vroey Béatrice Garcia Garcia Clothilde Roy Fran?ois Kidd Jean Henrion Pierre Deltenre | 2013 | Liver Int2013，，9： | 2 |
| 7 | Endoscopic Retrograde Cholangiopancreatography Gut Perforations: When to Wait! When to Operate!显示文摘 | Morgan Katherine A Fontenot Bennett B Ruddy Jean M Mickey Suzanne Adams David B | 2009 | The American Surgeon2009，，6： | 2 |
| 8 | Triayclglycerol Structure of Human Colostrum and Mature Milk 显示文摘 | Jean CM Philippe B | 1993 | American Oil Chemists'' Society1993，28，7： | 1 |
| 9 | Floral organ growth and carbohydrate content during pollen development in Lilium 显示文摘 | CHRISTOPHE C MONIQUE B JEAN C A | 1996 | American Journal of Botany1996，83，4： | 1 |
| 10 | Risk factor analysis for longterm tunneled dialysis catheter-related bacteremias 显示文摘 | Jean G Charra B Chazot C | 2002 | Nephron2002，91，3： | 1 |
| 11 | In vivo growth inhibitory effect of iterative wild-type p53 gene transfer in human head and neck carcinoma xenografts using glucosylated polyethylenimine nonviral vector显示文摘 | GILLES D JEAN L M MRIEL B H | 2002 | Cancer Gene Ther2002，，9： | 1 |
| 12 | Microleakage of class V composite restorations following Er:YAG and Nd:YAP laser irradiation compared to acid-etch: an in vitro study显示文摘 | Armengol V Jean A Enkel B | 2002 | Lasers Med Sci2002，17，2： | 1 |
| 13 | A Watermarking-Based Method for Informed Source Separation of Audio Signals with a Single Sensor显示文摘 | MATHIEU P LAURENT G JEAN M B | | 0，，06： | 1 |
| 14 | Restorergenes for different forms of brassica cytoplasmic male sterility map to a single nuclear locus that modifies transcripts of several mitochondrial genes显示文摘 | LI X Q JEAN M LANDRY B S | 1998 | Proc Natl Acad Sci USA1998，95，10： | 1 |
| 15 | Interferon alfa and gamma inhibit proliferation and collagen synthesis of human ito cells in culture显示文摘 | Ariane M Sylvie B Jean R | 1995 | Hepatology1995，21，4： | 1 |
| 16 | Efficient combination of recyclable task specific ionic liquid and microwave dielectric heating for the synthesis of lipophilic esters显示文摘 | Atef A Jean P B | 2005 | Organic Process Research & Development2005，9，2： | 1 |
| 17 | Cell - cycle - dependent expression of transforming growth factor β type Ⅰ receptor correlates with differential proliferative effects if TGF - β1 in articular chondrocytes显示文摘 | Nathalie F Jean - Pierre P | 1998 | Experimental cell research1998，243，： | 1 |
| 18 | Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures 显示文摘 | Alvaro GE Jean MS Luis B | 1995 | European Journal of Pharmacology1995，280，： | 1 |
| 19 | Vertebralplasty: clinical experience and follow-up results显示文摘 | Martin JB Jean B Sugiu K | 1999 | Bone1999，25，2： | 1 |
| 20 | Effcient combination of recyclable task specific ionic liquid and microwave dielectric heating for the synthesis of lipophilic esters显示文摘 | Atef A Jean P B | 2005 | Organic Process Research & Development2005，9，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员