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| 1 | Gamma irradiation of HIV-1显示文摘 | Richard A Smith Jesse Ingels John J Lochemes Joseph P Dutkowsky Linda L Pifer | 2001 | Journal of Orthopaedic Research2001，，5： | 2 |
| 2 | Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile:A pooled analysis显示文摘BACKGROUND The diagnosis of type 2 diabetes(T2D)in younger adults,an increasingly common public health issue,is associated with a higher risk of cardiovascular complications and mortality,which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger age.AIM To investigate the association between age at diagnosis and the cardiovascular risk profile in adults with T2D.METHODS A pooled dataset was used,comprised of data from five previous studies of adults with T2D,including 1409 participants of whom 196 were diagnosed with T2D under the age of 40 years.Anthropometric and blood biomarker measurements included body weight,body mass index(BMI),waist circumference,body fat percentage,glycaemic control(HbA1c),lipid profile and blood pressure.Univariable and multivariable linear regression models,adjusted for diabetes duration,sex,ethnicity and smoking status,were used to investigate the association between age at diagnosis and each cardiovascular risk factor.RESULTS A higher proportion of participants diagnosed with T2D under the age of 40 were female,current smokers and treated with glucose-lowering medications,compared to participants diagnosed later in life.Participants diagnosed with T2D under the age of 40 also had higher body weight,BMI,waist circumference and body fat percentage,in addition to a more adverse lipid profile,compared to participants diagnosed at an older age.Modelling results showed that each one year reduction in age at diagnosis was significantly associated with 0.67 kg higher body weight[95%confidence interval(CI):0.52-0.82 kg],0.18 kg/m^(2) higher BMI(95%CI:0.10-0.25)and 0.32 cm higher waist circumference(95%CI:0.14-0.49),after adjustment for duration of diabetes and other confounders.Younger age at diagnosis was also significantly associated with higher HbA1c,total cholesterol,low-density lipoprotein cholesterol and triglycerides.CONCLUSION The diagnosis of T2D earlier in life is associated with a worse cardiovascular risk factor profile,compared to those diagnosed later in life. | Mary M Barker Francesco Zaccardi Emer M Brady Gaurav S Gulsin Andrew P Hall Joseph Henson Zin ZinHtike Kamlesh Khunti Gerald P McCann Emma L Redman David R Webb Emma G Wilmot Tom Yates Jian Yeo Melanie J Davies Jack A Sargeant | 2022 | World Journal of Diabetes2022，13，3： | 2 |
| 3 | The KiSS-1 receptor GPR54 is essential for the development of the murine reproductive system显示文摘 | Sandrine Funes Joseph A Hedrick Galya Vassileva Lisa Markowitz Susan Abbondanzo Andrei Golovko Shijun Yang Frederick J Monsma Eric L Gustafson | 2003 | Biochemical and Biophysical Research Communications2003，，： | 2 |
| 4 | Mode of action of the COR15a gene on the freezing tolerance of Arabidopsis thaliana 显示文摘 | STEPONKUS P L UEMURA M JOSEPH R A | 1998 | Proc Nail Acad Sci USA1998，95，14： | 1 |
| 5 | Classification of remote sensing Images having high spectral resolution显示文摘 | P H Joseph A L David | 1996 | Remote Sensing Environment1996，57，3： | 1 |
| 6 | Cold Acclimation of Arabidopsis Thalian 显示文摘 | M Uemura R A Joseph and P L Steponkus | 1995 | Plant Physiol1995，，109： | 1 |
| 7 | Status and direction of communication technologies SiGe BiCMOS and RFCMOS 显示文摘 | Joseph A J Harame D L Jagannathan B | 2005 | Proc the IEEE2005，93，9： | 1 |
| 8 | Prevention and Control of Influenza with Vaccines Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2010显示文摘 | Fiore Anthony E Uyeki Timothy M Broder Karen Finelli Lyn Euler Gary L Singleton James A Iskander John K Wortley Pascale M Shay David K Bresee Joseph S Cox Nancy J | 2010 | MMWR. Morbidity and Mortality Weekly Report2010，，： | 1 |
| 9 | The Mismatch Effect: When Testosterone and Status Are at Odds 显示文摘 | JOSEPHS R A SELLERS J G NEWMAN M L | 2006 | Journal of Personality & Social Psychology2006，，90： | 1 |
| 10 | Dialkylimidazo- lium Chloroaluminate Melts: A New Class of Room-Temper- ature Ionic Liquids for Electrochemistry, Spectroscopy, and Synthesis 显示文摘 | John S W Joseph A L Robert A W | 1982 | Inorg Chem1982，21，： | 1 |
| 11 | Even>re- lated fMRI with simultaneous and continuous EEG: de- scription of the method and initial case report显示文摘 | Lemieux L Salek Haddadi A Josephs O | 2001 | Neuro- image2001，14，3： | 1 |
| 12 | Design and Synthesis of Biologically Active Peptides: Acids Can Modulate Activity of Synthetic Peptides 显示文摘 | Bryan A Joseph L Bennett J A | 2011 | Peptides2011，32，12： | 1 |
| 13 | Some properties of paucidisperse gymnosperm lignin sulfonates of different molecular weights显示文摘 | RICHARD F B JOHN A N JOSEPH L M | | 0，，04： | 1 |
| 14 | Soil Nitrogen Leaching Losses in Response to Freeze-Thaw Cycles 显示文摘 | Joseph G Henry A L | 2008 | Soil Biol Biochem2008，40，： | 1 |
| 15 | An Octahedral Template Based on a New Molecular Turn:Synthesis and Structure of a Model Complex and a Reactive,Diphenolic Ligand and Its Metal Complexes显示文摘 | Andrew L V Nathaniel W A Joseph A H | 1998 | Inorg Chem1998，37，： | 1 |
| 16 | Hyperh0m0cysteinemia leads to adverse cardiac remolding in hypertensive rats显示文摘 | Joseph J Washington A Joseph L | 2002 | Am J Physio Heart Circ Physiol2002，283，6： | 1 |
| 17 | Posttraumatic Osteoarthritis: A First Estimate of Incidence, Prevalence, and Burden of Disease显示文摘 | Thomas D Brown Richard C Johnston Charles L Saltzman J Lawrence Marsh Joseph A Buckwalter | 2006 | Journal of Orthopaedic Trauma2006，，10： | 1 |
| 18 | Expression of scatter factor in human bladder carcinoma 显示文摘 | JOSEPH A WEISS G H JIN L | 1995 | J Natl Cancer Inst1995，87，5： | 1 |
| 19 | Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding显示文摘 | Joseph L Kim Kurt A Morgenstern James P Griffith Maureen D Dwyer John A Thomson Mark A Murcko Chao Lin Paul R Caron | 1998 | Structure1998，，1： | 1 |
| 20 | Self-eare and qual- ity of life of heart failure patients at a multidisciplinary heart function clinic显示文摘 | Emily S Kevin J L Joseph A C | 2011 | J Cardiovase Nuts2011，26，5： | 1 |
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