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| 1 | 松花粉抗氧化性的体外实验研究显示文摘目的:通过体外试验对马尾松花粉的消炎、抗氧化性能进行评价。方法:四个模拟人类疾病过程中的生化反应系统为(1)MPO/H2O2系统主要模拟炎症反应,使中性粒细胞活化产生次氯酸;(2)Xan-XOD系统:模拟缺血再灌注,主要产生过氧化氢,超氧自由基和羟自由基;(3)Fenton系统,模拟体内炎性反应,从转铁蛋白或铁蛋白中释放出铁而产生羟自由基;(4)ABTS系统,用于总抗氧化能力的评估。结果:松花粉对以上反应系统所产生的过氧化氢、超氧自由基、羟自由基和次氯酸等活性氧系具有较好的清除作用,以浓度依赖关系抑制反应的发生并发挥抗氧化作用,对涉及炎症反应的MPO酶活性有一定的抑制作用。 | 鲍善芬 丛涛 J Illig H Schempp E F Elstner | 2005 | 营养学报2005，27，6： | 21 |
| 2 | 松花粉和松针提取物在亲脂性体外模型系统中抗氧化能力和机制的研究显示文摘目的:对松花粉和松针提取物在亲脂性抗氧化模型系统中的抗氧化能力和机制进行研究。方法:采用铜诱导的LDL氧化反应模型和Rose Bengal反应模型分别进行评价。结果:松花粉乙醇提取液具有较好的自由基链式反应阻断剂的作用,有效地推迟人血浆中低密度脂蛋白(LDL)氧化生成共轭二烯。松针乙醇提取液对LDL的保护作用优于松花粉。在Rose Bengal系统中,松花粉以清除自由基和螯合铜的两种机制抑制脂质过氧化反应的发生,而松针主要作为自由基清除剂发挥抗氧化作用。结论:松花粉和松针在两个亲脂性体外模型中均发挥很好的抗氧化能力,而抗氧化机制不尽相同。 | 鲍善芬 丛涛 Illig J Schempp H Elstner EF | 2006 | 军医进修学院学报2006，27，5： | 7 |
| 3 | Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants显示文摘 | Hinney A Nguyen T T Scherag A Friedel S Bronner G Muller T D Grallert H Illig T Wichmann H E Rief W Schafer H and Hebebrand J | | 0，，12： | 1 |
| 4 | Genes and lifestyle factors in obesity:Results from 12462 subjects from MONICA/KORA显示文摘 | Holzapfel C Grallert H Huth C Wahl S Fischer B Doring A Ruckert I M Hinney A Hebebrand J Wichmann H E Hauner H Illig T and Heid I M | | 0，，10： | 1 |
| 5 | IL-2 in combination with IFN-alpha and 5-FU verse tamoxifen in metastatic renal cell carcinoma:long-term results of a radomixed clinical trial显示文摘 | Atzpodien J Kirchner H Illiger H J | 2001 | Br J Cancer2001，85，： | 1 |
| 6 | IL - 2 in combination with IFN - alpha and 5 - FU versus tamoxifen in metastatic renal carcinoma: long - term results of a controlled randomized clinical trial显示文摘 | Atzpedien J Kirchner H Illiger HI | 2001 | Br J Cancer2001，85，8： | 1 |
| 7 | IL-2 in combination with IFN-alpha and 5-FU versus tamoxifen in metastatic renal cell carcinoma: long-term results of a controlled randomized clinical trial显示文摘 | Atzpodien J Kirchner H Illiger H J Metzner B Ukena D Schott H | 2001 | Br J Cancer2001，85，： | 1 |
| 8 | Colorectal cancer and polymor- phisms in DNA repair genes WRN,RMI1 and BUM显示文摘 | FRANK B HOFFMEISTER M KLOPP N ILLIG T CHANG- CLAUDE J BRENNER H | 2010 | Car- cinogenesis2010，31，3： | 1 |
| 9 | IL-2 in combination with IFN- alpha and 5-FU versus tamoxifen in metastatic renal carcinoma : long-term results of a controlled randomized clinical trial 显示文摘 | Atzpodien J Kirchner H Illiger HJ | 2001 | Br J Cancer2001，85，8： | 1 |
| 10 | IL- 2 in combination with INF - α and 5 - FU versus tamoxifen in metastatic renal carcinoma: long - term results of a controlled randomized clinical trial 显示文摘 | Atzpodien J Kirchner H Illiger HJ | 2001 | Br J Cancer2001，85，8： | 1 |
| 11 | IL-2 in combination with IFN-alpha and 5-Fu verse tamoxifen in metastatic renal cell carcinoma:long-term results of a controlled randomized clinical trial显示文摘 | Atzpodien J Kirehner H Illiger HJ | 2001 | Br J Cancer2001，85，： | 1 |
| 12 | Polymorphisms in inflammatory pathway genes and their association with colorectal cancer risk显示文摘 | Frank B Hoffmeister M Klopp N Illig T Chang- Claude J Brenner H | 2010 | Int J Cancer2010，127，： | 1 |
| 13 | A splice site variant in the sodium channel gene SCN1A confers risk of febrile seizures显示文摘 | K Schlachter U Gruber-Sedlmayr E Stogmann M Lausecker C Hotzy J Balzar E Schuh C Baumgartner J C. Mueller T Illig H E. Wichmann P Lichtner T Meitinger T M. Strom A Zimprich F Zimprich | 2009 | Neurology2009，，11： | 1 |
| 14 | A splice site variant in the sodium channel gene SCN1A confers risk of febrile seizures显示文摘 | K Schlachter U Gruber-Sedlmayr E Stogmann M Lausecker C Hotzy J Balzar E Schuh C Baumgartner J C. Mueller T Illig H E. Wichmann P Lichtner T Meitinger T M. Strom A Zimprich F Zimprich | 2009 | Neurology2009，，11： | 1 |
| 15 | IL-2 in combination with IFN-alpha and 5-FU verse tamoxifen in metastatic renal cell carcinoma: long-term result of a controlled randomised clinical trial 显示文摘 | Atzpodien J Kirchner H Illiger H J | 2001 | Br J Cancer2001，85，： | 1 |
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