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| 1 | Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease显示文摘The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD. | Courtney S Schaffert Michael J Duryee Carlos D Hunter Bartlett C Hamilton 3rd Amy L DeVeney Mary M Huerter Lynell W Klassen Geoffrey M Thiele | 2009 | World Journal of Gastroenterology2009，15，10： | 20 |
| 2 | The apparent, of polyphenol oxidase and phloridzin in the production of apple rooting cofactors显示文摘 | Bassuk N L Hunter L D Howard B H | 1981 | J Hort Sci1981，56，4： | 1 |
| 3 | Partial discharge monitoring for power transformers using UHF sensors, part 1 : sensors and signal interpretation显示文摘 | Judd M D Yang L Hunter B B | 2005 | IEEE Electrical Insulation Magazine2005，21，2： | 1 |
| 4 | Nylon-6 Nano- composites from Alkylammonium-modified Clay: The Role of Alkyl Tails on Exfoliation 显示文摘 | FORNES T D HUNTER D L PAUL D R | 2004 | Macromolecules2004，37，5： | 1 |
| 5 | Lumbar facet joint osteoarthritis: A review显示文摘 | Kaliehman L Hunter D | 2007 | Semin Arthritis Rheum2007，37，1： | 1 |
| 6 | Effect of sodium montmorillonite source on nyton6/clay nanocomposites显示文摘 | Fornes T D Hunter D L Paul D R | 2004 | Polymer2004，45，7： | 1 |
| 7 | Electromechanical actuation technology for the all-electric aircraft显示文摘 | Rubertus D P Hunter L D Cecere G J | 1984 | IEEE Trans on Aerospace and Electronic Systems1984，20，3： | 1 |
| 8 | Nylon-6 Nanocomposites from Alkylammonium-Modified Clay:The Role of Alkyl Tails on Exfoliation显示文摘 | Fornes T D Hunter D L Paul D R | 2004 | Macromolecules2004，37，： | 1 |
| 9 | Host responses in the bursa of Fabricius of chickens infected with virulent Marek's diseas virus显示文摘 | Abdul-Careem M F Hunter B D Lee L F | 2008 | Virology2008，379，2： | 1 |
| 10 | CART peptides显示文摘 | Kuhar M J Adams L D Hunter R G Vechia S D Smith Y | 2000 | Regul Pept2000，89，13： | 1 |
| 11 | Dietary intake of Cruciferous vegetables, Glutathione S-transferase (GST) polymorphisms and lung cancer risk in a Caucasian population显示文摘 | Wang L I Giovannucci E L Hunter D | 2004 | Cancer Causes Control2004，15，10： | 1 |
| 12 | Serologic survey for infectious pathogens in free-ranging American bison 显示文摘 | Taylor S K Lane V M Hunter D L | 1997 | Wildl Dis1997，33，： | 1 |
| 13 | Structural features of oxide coatings on aluminium显示文摘 | Hunter M S Robinson D L | 1953 | Journal of the Eleetrochemi-cal Society1953，100，： | 1 |
| 14 | Variation in concentrations of phloridzin and phloretinin apple foliage显示文摘 | Hunter M D Hull L A | 1993 | Phytochemistry1993，34，5： | 1 |
| 15 | Effect of seed maturation and genotype on seed vigor in maize显示文摘 | TeKrony D M Hunter J L | 1995 | Crop Science1995，35，3： | 1 |
| 16 | Intrauterine growth restriction: identification and management显示文摘 | Peleg D Kennedy C M Hunter S L | 1998 | Am Fam Physician1998，58，2： | 1 |
| 17 | Identification and comparison of marbofloxacin metabolitcs from the plasma of ball pythons (Python regius) and blue and gold macaws (Ara ararauna)显示文摘 | HUNTER R P KOCH D E COKE R L | 2007 | J Vet Pharmacol Ther2007，30，3： | 1 |
| 18 | The apparent of polyphenol oxidase and phlorizin in the production of apple rooting factors显示文摘 | Bassuk N L Hunter L D Howard B H | 1981 | J Hort Sci1981，56，4： | 1 |
| 19 | Structural features of anodic oxide films on aluminum显示文摘 | Keller F Hunter M S Obinson D L | 1953 | J Electrochem Soc1953，，100： | 1 |
| 20 | Observations on pigeon circovirus infection in Ontario 显示文摘 | Pare J A Brash M L Hunter D B | 1999 | Can Vet J1999，40，： | 1 |
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