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| 1 | Holocene palynological records and their responses to the controversies of climate system in the Shiyang River drainage basin显示文摘The Shiyang River drainage basin is located in the northwest margin of the Asian monsoon region. Previous studies reached different conclusions about Holocene climatic changes in the basin. Some studies suggested the Holocene climatic changes were mainly controlled by the Asian monsoon and that the climate was relatively humid during the early Holocene (11.6-7.1 cal ka BP). Other studies found the mid-Holocene Climatic Optimum (7.0-5.0 cal ka BP), and this climate condition was similar to the Holocene westerly wind pattern in arid Central Asia. The modern climate is affected by the Asian monsoon and westerly wind in the drainage basin, and the Holocene climatic records showed two different Holocene climatic patterns-a westerly wind pattern and monsoonal pattern. However, it remains unclear what caused the two different Holocene climatic patterns to co-exist in the region. The palynological records are the main evidence for the Holocene climatic changes in the basin. This paper focuses on palynological records for different parts of the drainage basin. Among them, QTH02, QTL-03 and Sanjiaocheng records are located in the terminal lake, and the Hongshuihe record is located in the middle reaches of the basin. In the terminal lake, the palynological records of QTH02 and QTL-03 are similar, but the Sanjiaocheng record differs. The difference is mainly affected by the variable pollen assemblages in the different locations of the lake basin. From comparison and synthesis of the four palynological records, we concluded that the millennial-scale Holocene climatic changes were affected by the combined effects of the Asian monsoon and westerly wind in the drainage basin, which show the complicated Holocene climatic pattern in the northwest margin of the Asian monsoon. | LI Yu WANG NaiAng LI ZhuoLun ZHANG HuaAn | 2011 | Chinese Science Bulletin2011，56，6： | 18 |
| 2 | Purification and characterization of a novel immunomodulatory protein from the medicinal mushroom Trametes versicolor显示文摘Bioactive proteins represent an important group of functional agents in medicinal mushrooms.Trametes versicolor(L.) Lloyd is a mushroom frequently used in traditional Chinese medicine for its anti-tumor and immunomodulatory activities.A new immunomodulatory protein from T.versicolor,named TVC,was purified by ammonium sulfate precipitation,ion-exchange chromatography and gel filtration chromatography.Sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis of the purified protein revealed a single band with a molecular weight of 15.0 kD.Native polyacrylamide gel analysis revealed a band at 30 kD,indicating that TVC exists in solution as a homodimer.Isoelectric focusing showed that TVC was an acidic protein with an isoelectric point of 4.0.TVC was found to lack carbohydrate modifications(based on periodic acid/Schiff staining) and it does not agglutinate mouse red blood cells,suggesting that TVC is not a lectin-like protein.Biological activity assays dem-onstrated that TVC can enhance the proliferation of splenocytes,while it has no stimulatory effects on CD4+and CD8+T cells. TVC markedly increases the proliferation of human peripheral blood lymphocytes in a dose-dependent manner and enhances the production of both nitric oxide and tumor necrosis factor-alpha by lipopolysaccharide-induced murine macrophages.The results indicate that TVC is an immunostimulant that can boost immune response.Comparison of the N-terminal amino acid residues and mass spectrometry results with the protein database revealed no homologous proteins. | LI Feng WEN HuaAn ZHANG YongJie AN Min LIU XingZhong | 2011 | Science China(Life Sciences)2011，54，4： | 11 |
| 3 | Genetic analysis and fine mapping of the pubescence gene GL6 in rice (Oryza sativa L.)显示文摘The pubescence of the leaf blade surface is an important agronomic characteristic for rice morphology and significantly influences rice growth as well as physiological characteristics. This characteristic was analyzed in F1 and F2 plants derived by crossing cultivar 75-1-127 with the indica cultivar Minghui 63, as well as the glabrous cultivar Lemont and indica cultivar 9311. Results indicated that the pubescence of the leaf blade surface was a dominant trait and controlled by a single gene. The GL6 gene was primarily mapped on rice chromosome 6 with recessive F2 population derived from 75-1-127/Minghui 63 by combining bulked segregation analysis and recessive class analysis using the Mapmaker3.0/MapDraw software. The genetic distances between the simple sequence repeat markers RM20491 and RM20547 were 7.2 and 2.2 cM, respectively. The GL6 gene was fine mapped in the interval between InDel-106 and InDel-115 at genetic distances of 0.3 and 0.1 cM, respectively. The large, recessive F2 population was derived from 75-1-127/Minghui 63. A high-resolution genetic and physical map of GL6 was constructed. Derived from the map-based sequences published by the International Rice Genome Sequencing Project, the GL6 gene was localized at an interval of 79 (japonica) and 116.82 kb (9311) bracketed by InDel-106 and InDel-115 within the BAC accession numbers AP008403 and AP005760. Seven annotated genes (japonica) and eight annotated genes (9311) were present. The basis was further set for GL6 cloning and function analysis. | ZENG YueHui ZHU YongSheng LIAN Ling XIE HongGuang ZHANG JianFu XIE HuaAn | 2013 | Chinese Science Bulletin2013，58，24： | 6 |
| 4 | From Green Super Rice to green agriculture:Reaping the promise of functional genomics research显示文摘Producing sufficient food with finite resources to feed the growing global population while having a smaller impact on the environment has always been a great challenge.Here,we review the concept and practices of Green Super Rice(GSR)that have led to a paradigm shift in goals for crop genetic improvement and models of food production for promoting sustainable agriculture.The momentous achievements and global deliveries of GSR have been fueled by the integration of abundant genetic resources,functional gene discoveries,and innovative breeding techniques with precise gene and whole-genome selection and efficient agronomic management to promote resource-saving,environmentally friendly crop production systems.We also provide perspectives on new horizons in genomic breeding technologies geared toward delivering green and nutritious crop varieties to further enhance the development of green agricul-ture and better nourish the world population. | Sibin Yu Jauhar Ali Shaochuan Zhou Guangjun Ren Huaan Xie Jianlong Xu Xinqiao Yu Fasong Zhou Shaobing Peng Liangyong Ma Dingyang Yuan Zefu Li Dazhou Chen Ruifeng Zheng Zhigang Zhao Chengcai Chu Aiqing You Yu Wei Susong Zhu Qiongyao Gu Guangcun He Shigui Li Guifu Liu Changhua Liu Chaopu Zhang Jinghua Xiao Lijun Luo Zhikang Li Qifa Zhang | 2022 | Molecular Plant2022，15，1： | 6 |
| 5 | Two classes of QC-LDPC cycle codes approaching Gallager lower bound显示文摘Dear editor,Many research results show that, for equivalent bit length, short nonbinary LDPC codes outperform binary LDPC codes by about 1 dB(1–3)Moreover, nonbinary LDPC codes have lower errorfloor, fast iterative decoding convergence, and strong ability of correcting burst errors. But the roadblock to their application is the high decoding complexity. Recently, significant studies on the low-complexity decoding algorithms of nonbinaryLDPC codes have been done [4]. | Hengzhou XU Huaan LI Mengmeng XU Dan FENG Hai ZHU | 2019 | Science China(Information Sciences)2019，62，10： | 2 |
| 6 | Proteomic analysis of blast-resistant near-isogenic lines derived from japonica rice, var. Yunyin, infected with Magnaporthe oryzae显示文摘Rice blast is one of the most devastating diseases in the world and outbreaks occur frequently.The differences in protein expression between blast resistant and susceptible near-isogenic lines(NILs)of japonica rice var.Yunyin infected with Magnaporthe oryzae were analyzed using proteomics,indicated that 67 different proteins were identified from 75 obtained proteins using the matrixassisted laser desorption/ionization time-of-flight mass spectrometry technique.Seven specific expression proteins,43 up-regulated proteins and 17 down-regulated proteins were identified among the 67 proteins.The bioinformatical analysis demonstrated that these 67 different proteins were involved in many biological physiological processes including five proteins related to photosynthesis,25 proteins related to metabolism,six proteins related to antioxidants,10 proteins related to protein synthesis and modification,five proteins related to signal transduction,four proteins related to adversity stress and 12 non-functional proteins.These identified proteins were directly or indirectly related to stress.Five proteins related to different physiological processes were selected.Their cDNA sequences were predicted and their expression patterns were analyzed using real-time PCR,demonstrated that the genes would response to M.oryzae and the response blindingly different between blast resistant and blast susceptible NILs. | Weimin Xue Xiaohui Mao Yidong Wei Lian Ling Yongsheng Zhu Shuilin He Jianfu Zhang Huaan Xie | 2014 | Chinese Science Bulletin2014，59，32： | 2 |
| 7 | Radiofrequency Ablation Versus Antiarrhythmic Medication for Treatment of Ventricular Premature Beats From the Right Ventricular Outflow Tract: Prospective Randomized Study显示文摘 | Zhiyu Ling Zengzhang Liu Li Su Vadim Zipunnikov Jinjin Wu Huaan Du Kamsang Woo Shaojie Chen Bin Zhong Xianbin Lan Jinqi Fan Yanping Xu Weijie Chen Yuehui Yin Saman Nazarian Bernhard Zrenner | 2014 | Circulation: Arrhythmia and Electrophysiology2014，，2： | 1 |
| 8 | Gradual daylength sensing coupled with optimum cropping modes enhances multi-latitude adaptation of rice and maize显示文摘To expand crop planting areas,reestablishment of crop latitude adaptation based on genetic variation in photoperiodic genes can be performed,but it is quite time consuming.By contrast,a crop variety that already exhibits multi-latitude adaptation has the potential to increase its planting areas to be more widely and quickly available.However,the importance and potential of multi-latitude adaptation of crop varieties have not been systematically described.Here,combining daylength-sensing data with the cropping system of elite rice and maize varieties,we found that varieties with gradual daylength sensing coupled with optimum cropping modes have an enhanced capacity for multi-latitude adaptation in China.Furthermore,this multi-latitude adaptation expanded their planting areas and indirectly improved China’s nationwide rice and maize unit yield.Thus,coupling the daylength-sensing process with optimum cropping modes to enhance latitude adaptability of excellent varieties represents an exciting approach for deploying crop varieties with the potential to expand their planting areas and quickly improve nationwide crop unit yield in developing countries. | Xiaoying Wang Jiupan Han Rui Li Leilei Qiu Cheng Zhang Ming Lu Rongyu Huang Xiangfeng Wang Jianfu Zhang Huaan Xie Shigui Li Xi Huang Xinhao Ouyang | 2023 | Plant Communications2023，4，1： | 1 |
| 9 | Direct and reverse overwrite processes in perpendicular recording显示文摘 | Li Shaoping Zhang Huaan | 2006 | IEEE Transactions on Magnetics2006，42，2： | 1 |
| 10 | Broadband Radio Bursts and Fine Structures during the Great Solar Event on 14 July 2000显示文摘 | Shujuan Wang Yihua Yan Ruizhen Zhao Qijun Fu Chengming Tan Long Xu Shijin Wang Huaan Lin | 2001 | Solar Physics (-)2001，，1： | 1 |
| 11 | Direct and reverse overwrite processes in perpendicular recording显示文摘 | Li Shaoping Zhang Huaan | 2006 | IEEE Transactions on Magnetics2006，42，2： | 1 |
| 12 | Broadband Radio Bursts and Fine Structures during the Great Solar Event on 14 July 2000显示文摘 | Shujuan Wang Yihua Yan Ruizhen Zhao Qijun Fu Chengming Tan Long Xu Shijin Wang Huaan Lin | 2001 | Solar Physics (-)2001，，1： | 1 |
| 13 | In situ chemosynthesized multi-wall carbon nanotube-conductive polyaniline nanocomposites:Characterization and application for a glucose amperometric biosensor显示文摘 | Zhong Huaan Yuan Ruo Chai Yaqin | 2011 | Talanta2011，85，1： | 1 |
| 14 | A fuzzy recommender systembased on the integration of subjective preferences and objec-tive information 显示文摘 | Cheng Lichen Wang Huaan | 2014 | Applied Soft Computing2014，，18： | 1 |
| 15 | An Anisotropic Geomechanical Model for Jointed Rock Masses at Taishan Nuclear Power Station, Southern China显示文摘An anisotropic geomechanical model for jointed rock mass is presented. Simultaneously with deriving the orthotropic anisotropy elastic parameters along the positive axis, the equivalent compliance matrix for the deflection axis orthotropic anisotropy was derived through a three-dimensional coordinate transformation. In addition, Singh's analysis of the stress concentration effects of intermittent joints was adopted, based on two groups of intermittent joints and a set of cross-cutting joints in the jointed rock mass. The stress concentration effects caused by intermittent joints and the coupling effect of cross-cutting joints along the deflection-axis are also considered. The proposed anisotropic mechanics parameters method is applied to determine the deformation parameters of jointed granite at the Taishan Nuclear Power Station. Combined with the deterministic mechanical parameters of rock blocks and joints, the deformation parameters and their variability in jointed rock masses are estimated quantitatively. The computed results show that jointed granite at the Taishan Nuclear Power Station exhibits typical anisotropic mechanical characteristics; the elastic moduli in the two horizontal directions were similar, but the elastic modulus in the vertical direction was much greater. Jointed rock elastic moduli in the two horizontal and vertical directions were respectively about 24% and 37% of the core of rock, showing weakly orthotropic anisotropy; the ratio of elastic moduli in the vertical and horizontal directions was 1.53, clearly indicating the transversely isotropic rock mass mechanical characteristics. The method can be popularized to solve other rock mechanics problems in nuclear power engineering. | ZHENG Wentang CHENG Xiaojiu WANG Huaan | 2013 | Acta Geologica Sinica(English Edition)2013，87，3： | 1 |
| 16 | Diagonal block orthogonal algebraic space-time block codes显示文摘 | Liu Chen Wu Zhenyang Zhao Huaan | 2005 | IEICE Trans Information and Systems2005，88，7： | 1 |
| 17 | Urothelial carcinoma of the urinary bladder with a component of acinar/tubellar type differentiation simulating prostatic adenocarcinoma显示文摘 | CHU PG LAU SK | 2004 | Hum Pathol2004，35，4： | 1 |
| 18 | SH3P2,an SH3 domain-containing protein that interacts with both Pib and AvrPib,suppresses effector-triggered,Pib-mediated immunity in rice显示文摘Plants usually keep resistance(R)proteins in a static state under normal conditions to avoid autoimmunity and save energy for growth,but R proteins can be rapidly activated upon perceiving pathogen invasion.Pib,the first cloned blast disease R gene in rice,encoding a nucleotide-binding leucine-rich repeat(NLR)protein,mediates resistance to the blast fungal(Magnaporthe oryzae)isolates carrying the avirulence gene AvrPib.However,the molecular mechanisms about how Pib recognizes AvrPib and how it is inactivated and activated remain largely unclear.In this study,through map-based cloning and CRISPR-Cas9 gene editing,we proved that Pib contributes to the blast disease resistance of rice cultivar Yunyin(YY).Furthermore,an SH3 domain-containing protein,SH3P2,was found to associate with Pib mainly at clathrin-coated vesicles in rice cells,via direct binding with the coiled-coil(CC)domain of Pib.Interestingly,overexpression of SH3P2 in YY compromised Pib-mediated resistance to M.oryzae isolates carrying AvrPib and Pib-AvrPib recognition-induced cell death.SH3P2 competitively inhibits the self-association of the Pib CC domain in vitro,suggesting that binding of SH3P2 with Pib undermines its homodimerization.Moreover,SH3P2 can also interact with AvrPib and displays higher affinity to AvrPib than to Pib,which leads to dissociation of SH3P2 from Pib in the presence of AvrPib.Taken together,our results suggest that SH3P2 functions as a“protector”to keep Pib in a static state by direct interaction during normal growth but could be triggered off by the invasion of AvrPib-carrying M.oryzae isolates.Our study reveals a new mechanism about how an NLR protein is inactivated under normal conditions but is activated upon pathogen infection. | Yunjie Xie Yupeng Wang Xiangzhen Yu Yuelong Lin Yongsheng Zhu Jinwen Chen Hongguang Xie Qingqing Zhang Lanning Wang Yidong Wei Yanjia Xiao Qiuhua Cai Yanmei Zheng Mo Wang Huaan Xie Jianfu Zhang | 2022 | Molecular Plant2022，15，12： | 1 |
| 19 | Medical micro-and nanomotors in the body显示文摘Attributed to the miniaturized body size and active mobility,micro-and nanomotors(MNMs)have demonstrated tremendous potential for medical applications.However,from bench to bedside,massive efforts are needed to address critical issues,such as cost-effective fabrication,on-demand integration of multiple functions,biocompatibility,biodegradability,controlled propulsion and in vivo navigation.Herein,we summarize the advances of biomedical MNMs reported in the past two decades,with particular emphasis on the design,fabrication,propulsion,navigation,and the abilities of biological barriers penetration,biosensing,diagnosis,minimally invasive surgery and targeted cargo delivery.Future perspectives and challenges are discussed as well.This review can lay the foundation for the future direction of medical MNMs,pushing one step forward on the road to achieving practical theranostics using MNMs. | Huaan Li Fei Peng Xiaohui Yan Chun Mao Xing Ma Daniela A.Wilson Qiang He Yingfeng Tu | 2023 | Acta Pharmaceutica Sinica B2023，13，2： | 0 |
| 20 | Sliding-Mode Control Based on Index control Law for MPPT in Photovoltaic Systems显示文摘A novel maximum power point tracking method based on sliding mode control and average state model of PV generation systems is developed.This method consists of two parts:term of constant control and term of index control.It is different from the conventional sliding mode control which uses a constant speed control law.The developed method uses a controllable sliding mode switching function which can automatically adjust the approaching speed,so as to enable the photovoltaic system to achieve fast dynamic response and stable output power.System simulations using MATLAB are performed.Compared with conventional methods,simulation results show that maximum power point tracking times for the novel method both in start-up phase and in cases of environmental changes can be shorten by more than 50%.A experimental platform of 150W PV system has been established to conduct tests.Experimental results show that the maximum power point tracking times both in start-up phase and in load stepping phase including the illumination change phase,can be significantly decreased.These results indicate that the developed method owns better dynamic response than constant speed control law.It can be used in photovoltaic generation system. | Zhiqiang Meng Wu Shao Jie Tang Huaan Zhou | 2018 | CES Transactions on Electrical Machines and Systems2018，2，3： | 0 |
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