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| 1 | 常规脂蛋白检测和载脂蛋白在心血管病预测中的比较显示文摘总胆固醇和高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)测量值对于心血管病风险评估至关重要,但对于其他脂质用于风险预测的效用一直存在争议。该研究纳入来自英国生物银行(Biobank)的无基线心血管病、未服用他汀类药物、有相关的脂质指标(n=346 686)的受试者。 | Welsh C Celis-Morales CA Brown R Mackay DF Lewsey J Mark PB Gray SR Ferguson LD Anderson JJ Lyall DM Cleland JG Jhund PS Gill J MR Pell JP Sattar N Welsh P 刘青(译) 叶鹏(摘、审校) | 2019 | 中华高血压杂志2019，27，7： | 10 |
| 2 | 利用抗高血压药相关的遗传变异发现其潜在的功效和副作用显示文摘通过研究药物靶蛋白基因的自然变异可以了解药物的功效。本研究旨在利用这种方法探索抗高血压药的潜在副作用和再利用潜力。研究者首先确定了血管紧张素转换酶抑制剂(angiotensin converting enzyme inhibitor,ACEI)、β受体阻滞剂和钙拮抗剂的合适代表基因。 | 刘青(译) 叶鹏(校) Gill D Georgakis MK Koskeridis F Jiang L Feng Q Wei WQ Theodoratou E Elliott P Denny JC Malik R Evangelou E Dehghan A Dichgans M Tzoulaki I | 2019 | 中华高血压杂志2019，0，9： | 3 |
| 3 | Hepatic Resection for Noncolorectal Nonendocrine Liver Metastases: Analysis of 1452 Patients and Development of a Prognostic Model显示文摘 | René Adam Laurence Chiche Thomas Aloia Dominique Elias Rémy Salmon Michel Rivoire Daniel Jaeck Jean Saric Yves Patrice Le Treut Jacques Belghiti Georges Mantion Gilles Mentha | 2006 | Annals of Surgery2006，，4： | 2 |
| 4 | Changes in efficiency and resource utilization after increasing experience with double balloon enteroscopy显示文摘AIM:To investigate changes in efficiency and resource utilization as a single endoscopist's experience increased with each subsequent 100 double balloon enteroscopy(DBE) procedures.METHODS:We reviewed consecutive DBE procedures performed by a single endoscopist at our center over 4 years.DBE was employed when the clinician deemed the procedure was needed for disease management.The approach(oral,anal or both) was chosen based on suspected location of the target lesion.All DBE was performed in a standard endoscopy room with a portable fluoroscopy unit.Fluoroscopy was used to aid in shortening the small intestine and reducing bowel loops.For oral DBE,measurements were taken from the incisors.For anal DBE,measurements were taken from the anal verge.Enteroscopy continued until the target lesion was reached,until the entire small intestine was examined,or until no further progress was deemed possible.The length of small intestine examined(cm),procedure duration(min),and fluoroscopy time(s) were analyzed for sequential groups of 100 DBE.Sub-groups of diagnostic and therapeutic procedures were analyzed using multivariable linear regression.RESULTS:802 consecutive DBE procedures were analyzed.For oral DBE,median [interquartile range(IQR)] length of small bowel examined was 230.8 cm(range:210-248 cm) and for anal DBE was 143.5 cm(range:100-180 cm).No significant increase in length examined was noted for either the oral or anal approach with advancing position in series.In terms of duration of procedure,the median(IQR) for oral DBE was 86 min(range:71-105 min) and for anal DBE was 81.3 min(range:67-105 min).When comparing by the position in series,there was a significant(P value < 0.001) decrease in procedure duration for both upper and lower procedures with increasing experience.Median(IQR) time of exposure to fluoroscopy for oral DBE was 190 s(114-275) compared to anal DBE which was 196.4 s(312-128).This represented a significant(P value < 0.001) decrease in the amount of fluoroscopy used with increasing position in series.For both oral and anal DBE,fluoroscopy time was reduced by greater than 50% over the course of 802 total procedures performed.Sub-group analysis was conducted on therapeutic and diagnostic groups.Out of 802 procedures,a total of 434 were considered therapeutic.Argon plasma coagulation was by far the most common therapeutic intervention performed.There was no evidence of a difference in length examined or fluoroscopy exposure among oral DBE for diagnostic and therapeutic procedures,P = 0.91 and P = 0.32 respectively.The median(IQR) for length was 235 cm(range:178-280 cm) for diagnostic vs 230 cm(range:180-275 cm) for therapeutic procedures;additionally,fluoroscopy time median(IQR) was 180 s(range:110-295 s) and 162 s(range:102-263 s) for no intervention and intervention.However,there was a significant difference in procedure duration among oral DBE(P < 0.001).The median(IQR) was 80 min(range:60-97 min) and 94 min(range:77-110 min) for diagnostic and therapeutic interventions respectively.CONCLUSION:For a single endoscopist,increased DBE experience with number of performed procedures is associated with increased efficiency and decreased resource utilization. | Neal C Patel William C Palmer Kanwar R Gill David Cangemi Nancy Diehl Mark E Stark | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，3： | 2 |
| 5 | Postconditioning in focal cerebral ischemia: Role of the mitochondrial ATP-dependent potassium channel显示文摘 | Emmanuel Robin Malika Simerabet Sidi Mohammed Hassoun Sebastien Adamczyk Benoit Tavernier Benoit Vallet Régis Bordet Gilles Lebuffe | 2010 | Brain Research2010，，： | 2 |
| 6 | Angiotensin-converting-enzyme inhibitors in stable vascular disease without left ventricular systolic dysfunction or heart failure: a combined analysis of three trials显示文摘 | Gilles R Dagenais Janice Pogue Kim Fox Marteen L Simoons Salim Yusuf | 2006 | The Lancet2006，，9535： | 2 |
| 7 | Comparison of 1,800 laparoscopic and open partial nephrectomies for single renal tumors显示文摘 | GILL I S KAVOUSSI L R LANE B R | 2007 | J Urol2007，178，1： | 1 |
| 8 | Epidermal growth factor receptor signaling is required for normal ovarian steroidogenesis and oocyte maturation显示文摘 | Jamnongjit M Gill A Hammes S R | 2005 | Proc Natl Acad Sci U S A2005，102，16： | 1 |
| 9 | Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation 显示文摘 | Wang L Gill R Pedersen TL | 2009 | J Lipid Res2009，50，2： | 1 |
| 10 | Advances in Urological Laparoscopy 显示文摘 | Gill I S Clayman R V Medougall E M | 1995 | J Urol1995，154，4： | 1 |
| 11 | The use of the holmium laser in the treatment of benign prostatic hyperplasia显示文摘 | Gilling P J Cass C B Malcolm A R | 1998 | Urology1998，51，： | 1 |
| 12 | Standard Karytype and nomenclature system for description of chromosome bands and structural aberrations in wheat (Triticum aestivum)显示文摘 | Gill B S B Friebe Endo T R | 1991 | Genome1991，34，： | 1 |
| 13 | Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritime显示文摘 | NELSON K E CLAYTON R A GILL S R | 1999 | Nature1999，399，： | 1 |
| 14 | Volumetric assessment of secondary alveolar bone grafting using cone beam computed tomography 显示文摘 | Oberoi S Chigurupati R Gill P | 2009 | Cleft Palate Craniofac J2009，46，5： | 1 |
| 15 | Development of guidelines to designate alleles using an STR multiplex system 显示文摘 | Gill P Sparkes R Kimpton C | 1997 | Forensic Sci Int1997，89，3： | 1 |
| 16 | A placebo- controlled study of liposome - mediated gene transfer to the nasal ep- ithelium of patients with cystic fibrosis显示文摘 | GILL D R SOUTHERN K W MOFORD K A | 1997 | Gene Ther1997，4，3： | 1 |
| 17 | Fetal safety of letrozoleand clomiphene citrate for ovulation induction显示文摘 | Forman R Gill S Moretti M | 2007 | J Obstet Gynaecol Can2007，29，8： | 1 |
| 18 | Standard karyotype and nomenclature system for description of chromosome bands and structural aberrations in wheat,(Triticum aestivum)显示文摘 | Gill B S Friebe B Endo T R | | 0，，04： | 1 |
| 19 | Using simple environmental variables to estimate below-ground productivity in grasslands显示文摘 | Gill R A Kelly R H Parton W J | | 0，，01： | 1 |
| 20 | Identification of a gene,MLL,that spans the breakpoint in 11q23 translocations associated with human leukemias显示文摘 | Ziemin-Van Der Poel S McCabe NR Gill HJ Espinosa R 3rd Patel Y Harden A Rubinelli P Smith SD LeBeau MM Rowley JD | | 0，，： | 1 |
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