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| 1 | Thermochemical Study on Ternary Complexes of Dysprosium with Aromatic Acid and Phenanthroline显示文摘 | Xiao Shengxiong Gu Huiwen LI Xu Zhang Jianjun Ren Ning | 2010 | J Chem Eng Data2010，55，9： | 1 |
| 2 | Analysis of gene mutations in Chinese patients with maple syrup urine disease显示文摘 | Nan Yang Lianshu Han Xuefan Gu Jun Ye Wenjuan Qiu Huiwen Zhang Zhuwen Gong Yafen Zhang | 2012 | Molecular Genetics and Metabolism2012，，4： | 1 |
| 3 | Evaluation of combined detection of nuclear factor erythroid 2-related factor 2 and glutathione peroxidase 4 in primary hepatic carcinoma and preliminary exploration of pathogenesis显示文摘This study aims to analyze the clinical significance and mechanism of nuclear factor erythroid 2-related factor 2(NRF2)and glutathione peroxidase 4(GPX4)in primary hepatic carcinoma(PHC).Methods:The expression of NRF2 and GPX4 in peripheral blood of patients with PHC was determined to analyze the diagnostic value of the two combined for PHC.The prognostic significance of NRF2 and GPX4 was evaluated by 3-year followup.Human liver epithelial cells THLE-2 and human hepatocellular carcinoma cells HepG2 were purchased,and the expression of NRF2 and GPX4 in the cells was determined.NRF2 and GPX4 aberrant expression vectors were constructed and transfected into HepG2,and changes in cell proliferation and invasion capabilities were observed.Results:The expression of NRF2 and GPX4 in patients with PHC was higher than that in patients with LC or VH(p<0.05),and the two indicators combined was excellent in diagnosing PHC.Moreover,patients with high expression of NRF2 and GPX4 had a higher risk of death(p<0.05).In in vitro experiments,both NRF2 and GPX4 expression was elevated in HepG2(p<0.05).HepG2 activity was enhanced by increasing the expression of the two,vice versa(p<0.05).Conclusion:NRF2 and GPX4 combined is excellent in diagnosing PHC,and promotes the malignant development of PHC. | JIE DUAN AIDONG GU WEI CHEN CHANGHAO CHEN FANGNAN SONG FAXI CHEN FANGFANG JIANG HUIWEN XING | 2023 | BIOCELL2023，47，12： | 0 |
| 4 | Fluorescence Spectroscopic Studies on the Interaction Between a New Bismuth(Ⅲ) Schiff Base Complex and Bovine Serum Albumin显示文摘In this work, the binding interaction between a new bismuth(HI) Schiff base complex{ [Bi(valen)]C1.2H2O} [H2valen=N,N′bis(2-hydroxy-3-methoxyphenylmethylidene)-2,6-pyridinediamine, C2 IH19N3O4]and bovine serum albumin(BSA) was studied via fluorescence quenching method. The static quenching constant KLBand some thermodynamic parameters(e.g.,△G^θ, △H^θ and △S^θ) of the interaction were estimated. In particular, thebinding site between the complex and BSA was explored by molecular docking. On the basis of the mechanism ofFOrster energy transfer, the binding distance between the bismuth(Ⅲ) Schiff base complex and BSA(Trp.213) as wellas the transfer efficiency was obtained. Furthermore, the effect of the bismuth(Ⅲ) Schiff base complex on the con-formation of BSA was investigated using synchronous fluorescence spectroscopy. | LI Xu LI Chuanhua JIANG Jianhong GU Huiwen WEI Deliang YE Lijuan HU Jilin XIAO Shengxiong ZHANG Hui LI Xia LI Qiangguo | 2017 | Chemical Research in Chinese Universities2017，33，2： | 0 |
| 5 | Synthesis and Bioactivity of a Novel Bismuthoxide Schiff-base Complex Derived from Salen-like Ligand and Bismuth(III) Nitrate显示文摘 | LI Chuanhua JIANG Jianhong LI Xu XIAO Shengxiong WEI Deliang JIANG Chao XIE Jinqi PENG Mengna GU Huiwen LI Qiangguo | 2016 | Chemical Research in Chinese Universities2016，32，2： | 0 |
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