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	题名	作者	年代	出处	被引量
1	Effect of oral epidermal growth factor on mucosal healing in rats with duodenal ulcer显示文摘AIM: To investigate the effect of epidermal growth factor (EGF) on mucosal healing in rats with duodenal ulcer.METHODS: Male Sprague-Dawley rats were randomly divided into sham operation without EGF, sham operation with EGF, duodenal ulcer without EGF, or duodenal ulcer with EGF groups. Additionally, normal rats without operation served as the control group. Duodenal ulcer was induced in rats by 300 mL/L acetic acid. Rats with EGF were orally administered at a dose of 60 μg/kg/day in drinking water on the next day of operation (day 1). Healing of duodenal ulcer was detected by haematoxylin and eosin staining. Cell growth of damaged mucosa was determined by the contents of nucleic acids and proteins. The level of EGF in duodenal mucosa was measured by ELISA.RESULTS: The pathological results showed that duodenal ulcer rats with EGF improved mucosal healing compared with those without EGF after day 5. Duodenal ulcer rats with EGF significantly increased duodenal DNA content compared with those without EGF on day 15 (6.44±0.54mg/g VS 1.45±0.52 mg/g mucosa, P<0.05). Duodenal RNA and protein contents did not differ between duodenal ulcer rats with and without EGF during the experimental period.Sham operation and duodenal ulcer rats with EGF significantly increased duodenal mucosal EGF content compared with those without EGF on day 5 (76.0±13.7 ng/g VS 35.7±12.9ng/g mucosa in sham operation rats, and 68.3±10.9 ng/gVS 28.3±9.2 ng/g mucosa in duodenal ulcer rats, P<0.05).CONCLUSION: Oral EGF can promote mucosal healing of the rats with duodenal ulcer by stimulating mucosal proliferation accompanied by an increase in mucosal EGF content.	Jane CJ Chao Kuo-Yu Liu Sheng-Hsuan Chen Chia-Lang Fang Chih-Wei Tsan	2003	World Journal of Gastroenterology2003，9，10：	9
2	Aberrant expression of chemokine receptor CCR4 in human gastric cancer contributes to tumor-induced immunosuppression显示文摘	Yeng YM Fang AL Zhou CJ	2011	Cancer Sci2011，102，7：	1
3	Spontaneous spinal epidural haematomas with repeated remission and relapse显示文摘	Chen CJ Fang W Chen CM	1997	Neuroradiology1997，39，：	1
4	Diltiazem suppresses collagen synthesis and IL-1 beta-induced TGF-beta 1 production on human peritoneal mesothelial cells显示文摘	Fang CC Yen CJ Chen YM		0，，05：	1
5	Spontaneous spinal epidural hematomas with repeated remission and relapse显示文摘	Chen CJ Fang W Chen CM	1997	Neuroradiology1997，39，：	1
6	Advances in understanding of pathogenesis of aHUS and HELLP显示文摘	Fang CJ Richards A Liszewski MK		0，，03：	1
7	Advances in the application of image processing fruit grading显示文摘	Fang C J Hua CJ	2014	Computer and Computing Technologies in Agriculture VII2014，419，：	1
8	Heart rate variability and daytime functioning in insomniacs and normal sleepers : prelimina- ry results显示文摘	Fang SC Huang CJ Yang TT	2008	J Psychosom Res2008，65，1：	1
9	The treatment targets of asthma: from laboratory to clinic 显示文摘	Fang C Corrigan CJ Ying S	2008	Inflamm Allergy Drug Targets2008，7，2：	1
10	Design,synthesis,and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents显示文摘	Kuo CJ Shie JJ Fang JM		0，，15：	1
11	Six-month angiographic results of primary angioplasty with adjunctive PercuSurge Guard-Wire device support: evaluation of the restenotic rate of the target lesion and the fate of the distal balloon occlusion site 显示文摘	Wu CJ Yang CH Fang CY	2005	Catheter Cardiovasc Interv2005，64，：	1
12	Manipulation of immune regulation in systemic lupus erythematosus显示文摘	La Cava A Fang CJ Singh RP	2005	Autoimmun Rev2005，4，：	1
13	Heart rate variability and daytime functioning in insomniacs and normal sleepers:Preliminary results 显示文摘	Fang SC Huang CJ Yang TY	2008	Journal of Psychosomatic Research2008，65，1：	1
14	Percutaneous anglo- plasty using a paclitaxel-coated balloon improves tar get lesion restenosis on inflow lesions of autogenous radiocephalic fistulas: a pilot study显示文摘	Lai CC Fang He Tseng CJ	2014	J Vase In- terv Radiol2014，25，41：	1
15	Blood and coagulation support in trauma care of hypertensive disorder complicating pregnancy显示文摘	Fang CJ	2010	Ostetrics Med2010，143，3：	1
16	Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy 显示文摘	Ryan CJ Smith MR Fang L	2010	J Clin Oncol2010，28，9：	1
17	Hepatitis B virus quasispecies susceptibility to entecavir confirms the relationship between genotypic resistance and patient virologic response显示文摘	Baldick CJ Eggers BJ Fang J		0，，06：	1
18	Advances in understanding of pathogenesis of aHUS and HELLP显示文摘	Fang CJ Richarcls A Liszewski MK	2008	Br J Haematol2008，143，3：	1
19	Injectable testosterone undecanoate has more favorable pharmacokinetics and pharmacodynamics than testosterone enanthate显示文摘	Partsch CJ Weinbauer GF Fang RY	1995	Eur J Endocrinol1995，132，4：	1
20	Pentoxifylline inhibits human peritonealmesothelial cell UwiIll and collagen synthesis-effects on TGF-beta显示文摘	Fang CC Yen CJ Chert YM	2000	Kidney Int2000，57，6：	1

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