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| 1 | Loose architecture of multi-level massive geospatial data based on virtual quadtree显示文摘This paper proposed a virtual quadtree (VQT) based loose architecture of multi-level massive geospatial data for integrating massive geospatial data dispersed in the departments of different hierarchies in the same sector into a unified GIS (Geographic Information System) platform. By virtualizing the nodes of the quad-tree,the VQT separates the structure of data organization from data storage,and screens the difference between the data storage in local computer and in the re-mote computers in network environment. And by mounting,VQT easily integrates the data from the remote computers into the local VQT so as to implement seam-less integration of distributed multi-level massive geospatial data. Based on that mode,the paper built an application system with geospatial data over 1200 GB distributed in 12 servers deployed in 12 cities. The experiment showed that all data can be seamlessly rapidly traveled and performed zooming in and zooming out smoothly. | YANG ChongJun,WU Sheng,REN YingChao,FU Li,ZHANG FuQing,WANG Gang,TAN Jian,LIU DongLin,MA ChaoJi & LIANG Li State Key Laboratory of Remote Sensing Science,Jointly Sponsored by the Institute of Remote Sensing Applications of Chinese Academy of Sciences and Beijing Normal University,Beijing 100101,China | 2008 | Science China(Technological Sciences)2008，51，S1： | 4 |
| 2 | Mussel‑Inspired Redox‑Active and Hydrophilic Conductive Polymer Nanoparticles for Adhesive Hydrogel Bioelectronics显示文摘Conductive polymers(CPs)are generally insoluble,and developing hydrophilic CPs is significant to broaden the applications of CPs.In this work,a mussel-inspired strategy was proposed to construct hydrophilic CP nanoparticles(CP NPs),while endowing the CP NPs with redox activity and biocompatibility.This is a universal strategy applicable for a series of CPs,including polyaniline,polypyrrole,and poly(3,4-ethylenedioxythiophene).The catechol/quinone contained sulfonated lignin(LS)was doped into various CPs to form CP/LS NPs with hydrophilicity,conductivity,and redox activity.These CP/LS NPs were used as versatile nanofillers to prepare the conductive hydrogels with long-term adhesiveness.The CP/LS NPs-incorporated hydrogels have a good conductivity because of the uniform distribution of the hydrophilic NPs in the hydrogel network,forming a well-connected electric path.The hydrogel exhibits long-term adhesiveness,which is attributed to the mussel-inspired dynamic redox balance of catechol/quinone groups on the CP/LS NPs.This conductive and adhesive hydrogel shows good electroactivity and biocompatibility and therefore has broad applications in electrostimulation of tissue regeneration and implantable bioelectronics. | Donglin Gan Tao Shuai Xiao Wang Ziqiang Huang Fuzeng Ren Liming Fang Kefeng Wang Chaoming Xie Xiong Lu | 2020 | Nano-Micro Letters2020，12，12： | 4 |
| 3 | A Multi–fluid Constrain for the Forming of Potash Deposits in the Savannakhet Basin: Geochemical Evidence from Halite显示文摘The Khorat Plateau on the Indochina Terrane is known to have formed during the closure of the Tethys Ocean, although the origin of its potash mineral deposits is a topic of current debate. Data from a borehole on Savannakhet Basin is used in this study to re-define the evaporation processes of the study area. Geochemical analyses of halite from various borehole-derived evaporite strata have elucidated the fluid sources from which these ores formed. Measured δ11 B indicated that ore deposits formed primarily due to evaporation of seawater, although non-marine fluids affected the later stages of the evaporation process. Fluctuations in B and Br concentrations in carnallite-and sylvite-rich strata indicate the influence of fresh water. Boron concentration in carnallite unit indicated the influence of hydrothermal fluids. From the relative timings of these various fluid influxes, the evolution of these evaporates can be divided into four stages:(1) an initial marine evaporation at the beginning of the deposit's formation, where seawater(and minor fresh water) trapped on the uplifted Khorat Plateau produced sediments and salts with Br contents lower than those of normal marine-derived evaporites;(2) a transgression stage, where seawater recharged the basin;(3) a hydrothermal infiltration stage, which was coeval with the late Yanshan movement; and(4) a stage of fresh water supply, as recorded by fluctuations in B and Br contents, inferring intermittent fresh water influx into the basin. Thus, although evaporites on the Savannakhet Basin primarily formed via marine evaporation, they were also influenced to a significant degree by the addition of non–marine fresh water and hydrothermal fluids. | REN Qianhui DU Yongsheng GAO Donglin LI Binkai ZHANG Xiying LIU Xiuting YUAN Xiaolong | 2018 | Acta Geologica Sinica(English Edition)2018，92，2： | 3 |
| 4 | Tailored prolapse surgery for the treatment of haemorrhoids and obstructed defecation syndrome with a new dedicated device: TST STARR Plus显示文摘 | Gabriele Naldini Jacopo Martellucci Roberto Rea Stefano Lucchini Michele Schiano di Visconte Angelo Caviglia Claudia Menconi Donglin Ren Ping He Domenico Mascagni | 2014 | International Journal of Colorectal Disease2014，，5： | 2 |
| 5 | An Objective Identification Technique for Regional Extreme Events显示文摘 | Ren Fumin Cui Donglin Gong Zhiqiang Wang Yanjiao Zou Xukai Li Yiping Wang Shigong Wang Xiaoling | 2012 | EN2012，，20： | 1 |
| 6 | Geochemistry and Zircon U-Pb Geochronology of Early Paleozoic S-type Granites in the Eastern Qilian Block,Northwest China显示文摘The Qilian Block(QB)is a Precambrian micro-continent located in the northeastern Qinghai–Tibet Plateau.Prevalent Lower Paleozoic granitic magmatic rocks crop out in the QB.A new integrated study of zircon U-Pb ages and systematic whole-rock geochemical data for the Xindian,Dongjiazhuang and Xiaogaoling granites in the eastern segment of the QB constrains their emplacement ages,petrogenesis,and regional evolutionary history.U-Pb dating reveals that the Xindian granite was emplaced 454 Ma,and both the Dongjiazhuang and Xiaogaoling granites were emplaced ca.440 Ma.Geochemical study shows that all granites belong to the high-K calc-alkaline to shoshonitic series and are S-type granites formed by partial melting of continental crust,mainly metagraywacke.We infer that these ca.454–445 Ma granites formed in a syn-collisional setting during the continental collisional between the Qaidam and Qilian blocks. | LIU Xiuting LI Binkai HAN Jilong REN Erfeng GAO Donglin DU Yongsheng REN Qianhui ZHANG Yan | 2021 | Acta Geologica Sinica(English Edition)2021，95，2： | 1 |
| 7 | Dose-dense biweekly docetaxel combined with 5-fluorouracil as first-line treatment in advanced gastric cancer: a phase II trial显示文摘 | Jian Xiao Yonghe Chen Wenyun Li Jiaying Gong Zhiyang Zhou Yanhong Deng Lei Wang Donglin Ren Jianping Wang Junsheng Peng Ping Lan | 2015 | Medical Oncology2015，，2： | 1 |
| 8 | An Objective Identification Technique for Regional Extreme Events显示文摘 | Ren Fumin Cui Donglin Gong Zhiqiang Wang Yanjiao Zou Xukai Li Yiping Wang Shigong Wang Xiaoling | 2012 | EN2012，，20： | 1 |
| 9 | Aging Resistance Evaluation of Aged Paper Reinforced with Different Nanocelluloses显示文摘Paper documents experience severe acidification and embrittlement.Nanocellulose is an excellent reinforcement material for paper documents owing to its compatibility and excellent mechanical strength.However,little research has been conducted on the aging resistance of nanocellulose-reinforced paper.In this study,six types of nanocelluloses were used to reinforce aged paper.The reinforcement and anti-aging performances were evaluated,and the anti-aging mechanism was further clarified.Nanocellulose with a high degree of polymerization can better enhance aged paper,and non-chemical nanocellulose also shows better anti-aging performance,such as nanocellulose prepared by mechanical or biological methods.However,nanocellulose prepared using chemical methods exhibits poor reinforcement and anti-aging performance.This is because it has a small particle size that is not beneficial for physical crosslinking with paper fibers.More importantly,the introduction of acidic or oxidizing groups on nanocellulose accelerates the acid hydrolysis and oxidation rate of paper fibers,especially nanocellulose prepared by 2,2,6,6-tetramethylpiperidine-1-oxyl oxidation,which should not be used to protect paper documents. | Xian Cao Bei He Jianlin Wang Chunhui Zhang Donglin Tang Qingyou Liang Chuanfu Liu Huiming Fan Junli Ren | 2023 | Paper And Biomaterials2023，8，3： | 0 |
| 10 | Unveiling mitophagy-mediated molecular heterogeneity and development of a risk signature model for colorectal cancer by integrated scRNA-seq and bulk RNA-seq analysis显示文摘Background:Accumulating researchers have recognized mitophagy as a key player in tumors,but few studies have investigated its role in the tumor microenvironment(TME).Advances in the technology of single-cell RNA sequencing(scRNA-seq)have allowed unveiling the concealed features of the TME at cellular resolution.This study aimed to elucidate the role of mitophagy within the TME of colorectal cancer(CRC)and to establish a mitophagy-mediated risk model.Methods:We assessed mitophagy-related pathway activities at both single-cell and tissue levels.Subsequently,an unsupervised clustering algorithm was employed to identify mitophagy-mediated subtypes.Furthermore,we developed a mitophagy-mediated risk signature(MMRS)using least absolute shrinkage and selection operator(LASSO)Cox analysis and constructed a MMRS model incorporating the risk score and clinical variables.Subsequently,we used quantitative reverse transcription polymerase chain reaction analysis to verify the expression of the screened genes.Results:We retrieved and annotated a total of 14,719 cells from eight samples in the scRNA-seq GSE132465 data set.The activities of mitophagy-related pathways were uniformly upregulated in cancer cells.Integrating with bulk RNA-seq data,we identified two mitophagy-mediated clusters(C1 and C2)with distinct characteristics and prognoses.C2 was identified as a mitophagy-high cluster.Then,we developed a five-gene MMRS via LASSO Cox analysis in The Cancer Genome Atlas(TCGA)cohort.We utilized the GSE39582 cohort to validate the efficacy of our model.The expression of CX3CL1 and INHBB was upregulated in CRC tissues.Conclusions:The present study identified two mitophagy-mediated CRC subtypes with distinct features.Our MMRS may provide potential therapeutic strategies for CRC.The findings of our work offer novel insights into the involvement of mitophagy in CRC. | Han Gao Qi Zou Linyun Ma Keyu Cai Yi Sun Li Lu Donglin Ren Bang Hu | 2023 | Gastroenterology Report2023，11，1： | 0 |
| 11 | On the Features, Status and Role of Adult Education显示文摘 | YU Donglin REN Qunying | 2014 | Journal of Zhouyi Research2014，，1： | 0 |
| 12 | Systemic delivery of microRNA for treatment of brain ischemia显示文摘Brain ischemia is the second leading cause of death and the third leading cause of disability in the world.Systemic delivery of microRNA,a class of molecules that regulate the expression of cellular proteins associated with angiogenesis,cell growth,proliferation and differentiation,holds great promise for the treatment of brain ischemia.However,their therapeutic efficacy has been hampered by poor delivery efficiency of microRNA.We report herein a platform technology based on microRNA nanocapsules,which enables their effective delivery to the disease sites in the brain.Exemplified by microRNA-21,intravenous injection of the nanocapsules into a rat model of cerebral ischemia could effectively ameliorate the infarct volume,neurological deficit and histopathological severity. | Chaoyong Liu Jing Wen Dai Li Hongzhao Qi Lina Nih Jialin Zhu Duo Xu Yu Ren Shanshan Zhang Donglin Han Huanhuan Jia Junhu Zhou Meng Qin Jialing Wu Xubo Yuan Ji Liu Jin Zhao Chunsheng Kang Yunfeng Lu | 2021 | Nano Research2021，14，9： | 0 |
| 13 | External rectal prolapse:abdominal or perineal repair for men?A retrospective cohort study显示文摘Background:External rectal prolapse is a relatively rare disease,in which male patients account for a minority.The selection of abdominal repair or perineal repair for male patients has rarely been investigated.Methods:Fifty-one male patients receiving abdominal repair(laparoscopic ventral rectopexy)or perineal repair(Delorme or Altemeier procedures)at the Sixth Affiliated Hospital of Sun Yat-sen University(Guangzhou,China)between March 2013 and September 2019 were retrospectively analysed.We compared the recurrence,complication rate,post-operative defecation disorder,length of stay,and quality of life between the abdominal and perineal groups.Results:Of the 51 patients,45 had a complete follow-up,with a median of 48.5 months(range,22.8–101.8 months).A total of 35 patients were under age 40 years.The complication rate associated with abdominal repair was less than that associated with perineal repair(0%vs 20.7%,P=0.031)and the recurrence rate was also lower(9.5%vs 41.7%,P=0.018).Multivariate analysis showed that perineal repair(odds ratio,9.827;95%confidence interval,1.296–74.50;P=0.027)might be a risk factor for recurrence.Moreover,only perineal repair significantly improved post-operative constipation status(preoperative vs post-operative,72.4%vs 25.0%,P=0.001).There was no reported mortality in either of the groups.No patient’s sexual function was affected by the surgery.Conclusions:Both surgical approaches were safe in men.Compared with perineal repair,the complication rate and recurrence rate for abdominal repair were lower.However,perineal repair was better able to correct constipation. | Bang Hu Qi Zou Zhenyu Xian Dan Su Chao Liu Li Lu Minyi Luo Zixu Chen Keyu Cai Han Gao Hui Peng Wuteng Cao Donglin Ren | 2022 | Gastroenterology Report2022，10，1： | 0 |
| 14 | Analytical Models of on-Chip Hardware Trojan Detection Based on Radiated Emission Characteristics显示文摘Since many third parties involved in integrated circuit(IC)manufacturing,hardware Trojans malicious implantation have become a threat to the IC industry.Therefore,varieties of reliable hardware Trojan detection methods are needed.Since electromagnetic radiation is an inherent phenomenon of electronic devices,there are significant differences in the electromagnetic radiated characteristics for circuits with different structures and operating states.In this paper,a novel hardware Trojan detection method is proposed,which considers the electromagnetic radiation differences caused by hardware Trojan implantation.Experiments of detecting hardware Trojan in field programmable gate arrays show that the proposed method can effectively distinguish the ICs with Trojan from the ones without Trojan by the radiated emission. | Fan ZHANG Dongrong ZHANG Qiang REN Aixin CHEN Donglin SU | 2024 | Chinese Journal of Electronics2024，33，2： | 0 |
| 15 | Evaluation of boron isotopes in halite as an indicator of the salinity of Qarhan paleolake water in the eastern Qaidam Basin, western China显示文摘In this study, nineteen brine samples from the Qarhan Salt Lake(QSL) in western China were collected and analyzed for boron(B) and chlorine(Cl) concentrations, total dissolved solids(TDS), pH values and stable B isotopic compositions. The B concentrations and δ^(11) B values of brines in the QSL range from 51.6 mg/L to138.4 mg/L, and from +9.32& to +13.08&, respectively. By comparison of B concentrations and TDS of brines in QSL with evaporation paths of brackish water, we found that B enrichment of brines primarily results from strong evaporation and concentration of Qarhan lake water. Combining with comparisons of B concentrations, TDS, p H values and δ^(11) B values of brines, previously elemental ratios(K/Cl, Mg/Cl, Ca/Cl, B/Cl) and δ^(11) B values of halite from a sediment core(ISL1 A), we observe good correlations between B concentrations and TDS, TDS and pH values, pH and δ^(11) B values of brines, which demonstrate that higher B concentrations and more positive δ^(11) B values of halite indicate higher salinity of the Qarhan paleolake water as well as drier paleoclimatic conditions. Based on this interpretation of the δ^(11) B values of halite in core ISL1 A, higher salinity of the Qarhan paleolake occurred during two intervals, around 46-34 ka and26-9 ka, which are almost coincident with the upper and lower halite-dominated salt layers in core ISL1 A,drier climate phases documented from the δ^(18) O record of carbonate in core ISL1 A and the paleomoisture record in monsoonal central Asia, and a higher solar insolation at 30°N. These results demonstrate that the δ^(11) B values of halite in the arid Qaidam Basin could be regarded as a new proxy for reconstructing the salinity record of paleolake water as well as paleoclimate conditions. | Yongsheng Du Qishun Fan Donglin Gao Haicheng Wei Fashou Shan Binkai Li Xiangru Zhang Qin Yuan Zhanjie Qin Qianhui Ren Xueming Teng | 2019 | Geoscience Frontiers2019，10，1： | 0 |
| 16 | A sampling method based on forecasting and combinatorial optimization for high performance A/B testing显示文摘1 Introduction A/B testing[1]is a popular statistical method for many applications,especially,widely used by Internet companies for user experience research.The sampling algorithm is an important part of A/B testing and has a critical impact on the performance of A/B testing.There are two challenges to achieving high performance in A/B testing.(1)The features of individuals being sampled change over time and the sampling results used for evaluation are valid only for a period of time.(2)The sampling methods in A/B testing require determining whether the two groups of samples have an identical distribution while Simple Random Sampling(SRS)has a different purpose,which only concerns whether the sample distribution is identical to the population. | Fan LI Tiancheng ZHANG Shengjia CUI Hengyu LIU Zhibin REN Donglin DI Xiao WANG Po ZHANG Ge YU | 2023 | Frontiers of Computer Science2023，17，6： | 0 |
| 17 | Diverse Regulations of Viral and Host Genes in Tomato Germplasms Responding to Tomato Yellow Leaf Curl Virus Inoculation显示文摘Tomato yellow leaf curl virus(TYLCV)is the dominating pathogen of tomato yellow leaf curl disease that caused severe loss to tomato production in China.In this study,we found that a TYLCV-resistant tomato line drastically reduced the accumulation of viral complementary-sense strand mRNAs but just moderately inhibited that of viral DNA and virion-sense strand mRNAs.However,two other resistant lines did not have such virus inhibition pattern.Analysis of differential expressed genes showed that the potential host defense-relevant processes varied in different resistant tomatoes,as compared to the susceptible line,suggesting a diversity of tomato TYLCV-resistance mechanisms. | Wanyu XIAO Jianghua HUANG Xianyu ZHOU Hailong REN Jing ZHANG Donglin XU | 2023 | Agricultural Biotechnology2023，12，3： | 0 |
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