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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Oleanolic Acid Induces Apoptosis in Human Leukemia Cells through Caspase Activation and Poly(ADP-ribose) Polymerase Cleavage显示文摘它被看了那 Fructus Ligustri Lucidi (FLL ) ,有希望的 traditionalChinesemedicine,能禁止肿瘤的生长。然而,有效部件和 FLL 的分子的机制行动禁止肿瘤增长是不清楚的。在这研究,我们表明了 thatoleanolic 酸(OA ) , FLL 的一个主要化学部件,在文化禁止了人的白血病 HL60 房间的增长。MTT 试金与 FLL 粗略的摘录显示出 HL60 细胞的那个处理或 OA 戏剧性地在 time-dependentmanner 和 dose-dependentmanner 堵住了目标肿瘤房间的生长。原子核和 DNA 破碎的词法变化证明 apoptotic 房间死亡在与 FLL 摘录(20 mg/ml ) 或 OA 对待以后发生在 HL60 房间(3.65xl0 ^(-2) mg/ml ) 。而且,流动 cytometry 试金与 FLL 显示出 HL60 房间的那个处理或 OA 引起了 G1 和 sub-G1 潜水艇人口的增加的累积。蛋白质印迹分析证明 caspase-9and caspase-3 被激活,由劈开伴随了 poly (自动数据处理核糖) 在目标房间的聚合酶(PARP ) 在导致 FLL 或导致 OA 的 apoptosis 期间。这些结果建议 OA 由通过 caspases 的激活和 PARP 的劈开向目标肿瘤房间施加它的 cytotoxicity 充当 FLL 的有效部件。 | Pengxia ZHANG Hongmei LI Dong CHEN Juhua NI Yuming KANG Shuqiu WANG | 2007 | Acta Biochimica et Biophysica Sinica2007，39，10： | 26 |
| 3 | Influence of starch sources and dietary protein levels on intestinal functionality and intestinal mucosal amino acids catabolism in broiler chickens显示文摘Background: There is growing interest in carbohydrate and protein nutrition to enhance the efficiency of animal production.Reduced-crude protein diets depress environmental pollution and feeding cost,but the challenge to their adoption is maintaining digestive function and growth performance of birds.The present study was conducted to evaluate the influence of different dietary starch sources and protein levels on intestinal functionality and mucosal amino acid catabolism.Methods: Six dietary treatments,based on maize and soybean meal,were offered to 360 AA+male chicks from 6 to 35 d post-hatch as a 3 × 2 factorial array.Either waxy rice or amylose was added to a conventional maize-soy diet to provide three sources of starch with different digestion rates and relatively high and low dietary protein levels.Growth performance,parameters of intestinal functionality and concentrations of free amino acid in the portal circulation were determined.Results: In the grower phase,starch source influenced(P < 0.02) weight gain as diets containing amylose supported significantly higher weight gains than waxy rice.Significant increase of ileal ATP concentrations and Na^+/K^+-ATPase activity were found in amylose treatment.Also,amylose decreased BrdU positive cell numbers and down-regulated m RNA expression for CASP-3.GOT activity in the ileum was higher(P < 0.01) in birds offered low protein diets and there was a trend(P = 0.057) for waxy rice as a starch source to increase ileal GOT activities.There was a significant influence on the concentration of seventeen amino acids in the portal circulation with tryptophan the one exception.Waxy rice as a starch source generated 13.6% and 22.4% numerically higher concentrations of non-essential amino acids than maize and amylose,respectively.Conclusions: Amino acid catabolism in the gut mucosa is subject to nutritional regulation.Given that amino acids can be spared from catabolism in the gut mucosa by supplementation of amylose,it follows their post-enteral availability would be improved and intestinal energy would be derived more efficiently from glucose. | Dafei Yin Peter H.Selle Amy F.Moss Youli Wang Xiaoyu Dong Zhibin Xiao Yuming Guo Jianmin Yuan | 2019 | Journal of Animal Science and Biotechnology2019，10，3： | 10 |
| 4 | Three-Dimensional Heat Transfer Analysis for A Thermal Energy Storage Canister显示文摘High temperature latent thermal storage is one of the critical techniques for a solar dynamic power system. This paper presents results from heat transfer analysis of a phase change salt containment canister A three-dimensional analysis program is developed to model heat transfer in a PCM canister. Analysis include effects of asymmetric circumference heat flux, conduction in canister walls, liquid PCM and solid PCM, void volume change and void location, and conduction and radiation across PCM vapor void. The PCM phase change process is modeled using the enthalpy method and the simulation results are compared with those of other two- dimensional investigations. It’s shown that there are large difference with two-dimensional analysis, therefore the three-dimensional model is necessary for system design of high temperature latent thermal storage. | Hou Xinbin, Xin Yuming, Yang Chunxin, Yuan Xiugan (Dept.of Flight Vehicle Design and Applied Mechanics, Beijing University of Aeronautics and Astronautics, Beijing, 100083.) Dong Keyong (Stirling Engine Research and Develop Center, Shanghai Marine Diesel | 2001 | Journal of Thermal Science2001，10，1： | 9 |
| 5 | Investigation on the fabrication of lightweight aggregate with acid-leaching tailings of vanadium-bearing stone coal minerals and red mud显示文摘Proper treatment of acidleaching tailings(ALTs)of vanadiumbearing stone coal minerals is of great urgency.One approach is adding it into the raw materials during the preparation of lightweight aggregate(LWA).But clay is always needed.In this paper,another solid waste,red mud,was mixed with ALTs as a source of flux components instead of clay.Evaluation of the physical characteristics,morphological structures,as well as crystal phases during the sintering process were investigated.When their mixtures with a proper ratio were sintered at 1080℃,a glassy phase with certain viscosity was formed,and the gases generated simultaneously were encapsulated by the melt.Finally,LWA with a onehour water absorption as low as 1.46%,a bulk density as low as 728.76 kgm 3 and a compressive strength as high as 10.77 MPa was fabricated. | Chunguang Song Hongling Zhang Yuming Dong Lili Pei Honghui Liu Junsheng Jiang Hongbin Xu | 2021 | Chinese Journal of Chemical Engineering2021，34，4： | 6 |
| 6 | Advancements in the preparation of high-performance liquid chromatographic organic polymer monoliths for the separation of small-molecule drugs显示文摘The various advantages of organic polymer monoliths, including relatively simple preparation processes,abundant monomer availability, and a wide application range of pH, have attracted the attention of chromatographers. Organic polymer monoliths prepared by traditional methods only have macropores and mesopores, and micropores of less than 50 nm are not commonly available. These typical monoliths are suitable for the separation of biological macromolecules such as proteins and nucleic acids, but their ability to separate small molecular compounds is poor. In recent years, researchers have successfully modified polymer monoliths to achieve uniform compact pore structures. In particular, microporous materials with pores of 50 nm or less that can provide a large enough surface area are the key to the separation of small molecules. In this review, preparation methods of polymer monoliths for high-performance liquid chromatography, including ultra-high cross-linking technology, post-surface modification, and the addition of nanomaterials, are discussed. Modified monolithic columns have been used successfully to separate small molecules with obvious improvements in column efficiency. | Xiali Ding Jing Yang Yuming Dong | 2018 | Journal of Pharmaceutical Analysis2018，8，2： | 5 |
| 7 | Extracting and Measuring Uncertain Biomedical Knowledge from Scientific Statements显示文摘Purpose:Given the information overload of scientific literature,there is an increasing need for computable biomedical knowledge buried in free text.This study aimed to develop a novel approach to extracting and measuring uncertain biomedical knowledge from scientific statements.Design/methodology/approach:Taking cardiovascular research publications in China as a sample,we extracted subject-predicate-object triples(SPO triples)as knowledge units and unknown/hedging/conflicting uncertainties as the knowledge context.We introduced information entropy(IE)as potential metric to quantify the uncertainty of epistemic status of scientific knowledge represented at subject-object pairs(SO pairs)levels.Findings:The results indicated an extraordinary growth of cardiovascular publications in China while only a modest growth of the novel SPO triples.After evaluating the uncertainty of biomedical knowledge with IE,we identified the Top 10 SO pairs with highest IE,which implied the epistemic status pluralism.Visual presentation of the SO pairs overlaid with uncertainty provided a comprehensive overview of clusters of biomedical knowledge and contending topics in cardiovascular research.Research limitations:The current methods didn’t distinguish the specificity and probabilities of uncertainty cue words.The number of sentences surrounding a given triple may also influence the value of IE.Practical implications:Our approach identified major uncertain knowledge areas such as diagnostic biomarkers,genetic polymorphism and co-existing risk factors related to cardiovascular diseases in China.These areas are suggested to be prioritized;new hypotheses need to be verified,while disputes,conflicts,and contradictions need to be settled.Originality/value:We provided a novel approach by combining natural language processing and computational linguistics with informetric methods to extract and measure uncertain knowledge from scientific statements. | Xin Guo Yuming Chen Jian Du Erdan Dong | 2022 | Journal of Data and Information Science2022，7，2： | 3 |
| 8 | Determination of pKa values of alendronate sodium in aqueous solution by piecewise linear regression based on acid-base potentiometric titration显示文摘As a mono-sodium salt form of alendronic acid,alendronate sodium presents multi-level ionization for the dissociation of its four hydroxyl groups.The dissociation constants of alendronate sodium were determined in this work by studying the piecewise linear relationship between volume of titrant and p H value based on acidbase potentiometric titration reaction.The distribution curves of alendronate sodium were drawn according to the determined p Ka values.There were 4 dissociation constants(pKa_1=2.43,pKa_2=7.55,pKa_3=10.80,pKa_4=11.99,respectively) of alendronate sodium,and 12 existing forms,of which 4 could be ignored,existing in different p H environments. | Jing Ke Hanfei Dou Ximin Zhang Dushimabararezi Serge Uhagaze Xiali Ding Yuming Dong | 2016 | Journal of Pharmaceutical Analysis2016，6，6： | 2 |
| 9 | Efficacy and safety of entecavir compared to lamivudine in nucleoside-na?ve patients with chronic hepatitis B: a randomized double-blind trial in China显示文摘 | Guangbi Yao Chengwei Chen Weilun Lu Hong Ren Deming Tan Yuming Wang Daozheng Xu Zhengrong Jiang Jessica Liu Dong Xu Laurie MacDonald | 2007 | Hepatology International2007，，3： | 1 |
| 10 | Enhanced Glass Giber-reinforced Phenolphthalein Poly (ether ketone) Composites by Blending Poly (phenylene sulfide)显示文摘 | Yang Yuming Binyao U Dong Lishong | 1996 | Journal of Applied Polymer Science1996，59，3： | 1 |
| 11 | Synthesis and crosslinking of hydroxyl-functionalized sulfonated poly(ether ether ketone) copolymer as candidates for proton exchange membranes显示文摘 | Shaoguang Feng Yuming Shang Yaowu Wang Guoshun Liu Xiaofeng Xie Wenqi Dong Jingming Xu V.K. Mathur | 2010 | Journal of Membrane Science2010，，1： | 1 |
| 12 | Regulatory Polymorphisms in the Promoter of CXCL10 Gene and Disease Progression in Male Hepatitis B Virus Carriers显示文摘 | Guohong Deng Gangqiao Zhou Rong Zhang Yun Zhai Wenli Zhao Zehui Yan Chunqing Deng Xiaoyan Yuan Baoyan Xu Xiaojia Dong Xiumei Zhang Xuqing Zhang Zhijian Yao Yan Shen Boqing Qiang Yuming Wang Fuchu He | 2008 | Gastroenterology2008，，3： | 1 |
| 13 | Zinc glycerolate with lanthanum stearate to inhibit the thermal degradation of poly(vinyl chloride)显示文摘 | Jiang Pingping Song Yinyin Dong Yuming | 2013 | Appl Polym Sci2013，127，36： | 1 |
| 14 | Catalytic ozonation of azo dye active brilliant red X-3B in water with natural mineral brucite 显示文摘 | Dong Yuming He Kun Zhao Bo | 2007 | Catalysis Communication2007，8，11： | 1 |
| 15 | Low Cost Multi-channels Gallium Arsenide Absorption-based Fiber Optic Temperature Sensing System 显示文摘 | DONG Yuming JIAO Guohua LU Yuanfu | 2013 | Proceedings of SPIE(S0277-786X)2013，9044，90： | 1 |
| 16 | Catalytic ozonation of phenol in water with natural brucite and magnesia显示文摘 | He Kun Dong Yuming Li Zhen at al | 2008 | Journal of Hazardous Materials2008，159，23： | 1 |
| 17 | β-MnO 2 nanowires: A novel ozonation catalyst for water treatment显示文摘 | Yuming Dong Hongxiao Yang Kun He Shaoqing Song Aimin Zhang | 2008 | Applied Catalysis B Environmental2008，，3： | 1 |
| 18 | Novel Two- Phase Catalysis with Organometallic Compounds for Epoxidation of Vegetable Oils by Hydrogen Peroxide显示文摘 | Jiang Pingping Chen Min Dong Yuming | 2010 | J Am Oil Soc2010，87，： | 1 |
| 19 | Regulatory Polymorphisms in the Promoter of CXCL10 Gene and Disease Progression in Male Hepatitis B Virus Carriers显示文摘 | Guohong Deng Gangqiao Zhou Rong Zhang Yun Zhai Wenli Zhao Zehui Yan Chunqing Deng Xiaoyan Yuan Baoyan Xu Xiaojia Dong Xiumei Zhang Xuqing Zhang Zhijian Yao Yan Shen Boqing Qiang Yuming Wang Fuchu He | 2008 | Gastroenterology2008，，3： | 1 |
| 20 | Catalytic activity and stability of Y zeolite for phenol degradation in the presence of ozone显示文摘 | Yuming Dong Hongxiao Yang Kun He | | 0，，： | 1 |
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