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264篇 您的检索式:作者名="DOOLEY M"
    题名 作者 年代 出处 被引量
1Mycophenolate versus azathioprine as maintenance therapy for lupus nephritis显示文摘Dooley M A Jayne D Ginzler E M 2011N Engl J Med2011,365,20:1
2Donepezil:A review of its use in Alzheimer's disease 显示文摘DOOLEY M LAMB ItM 2000Adis International2000,16,3:1
3Newer therapeutic approaches for systemic lupus erythematosus:Immunosuppressive agents显示文摘DOOLEY M A GINZLERE M 2006Rh Dis Clin North Am2006,32,1:1
4Urapidil:A reappraisal of its use in the management of hypertension 显示文摘DOOLEY M GOA K L 1998Drugs1998,56,5:1
5Kinetics of catalyzed acid/acid and acid/aldehyde condensation reactions to non-symmetric ketones显示文摘Travis S H Dooley K M 2003Catalysis Today2003,85,234:1
6Improved fish species identification by use of lab-on-a-chip technology 显示文摘Dooley J J Sage H D Brown H M 2005Food Control2005,16,7:1
7Supply networks and complex adaptive systems:controlversus emergence显示文摘CHOIT Y DOOLEY K J RUNGTUSANATHAM M 2001Journal of Operations Manage-ment2001,19,:1
8A Jet Fuel Surrogate Formulated by Real Fuel Properties 显示文摘Dooley S Won S H Chaos M 2010Combustion and Flame2010,157,12:1
9Supply networks and complex adaptive systems:Control versus emergence显示文摘Choi T Y Dooley K J and Rungtusanatham M 2001Journal of Operations Management2001,19,3:1
10Aire-dependent alterations in medullary thymic epithelium indicate a role for Aire in thymic epithelial differentiation 显示文摘Gillard GO Dooley J Erickson M 2007J Immunol2007,178,5:1
11Transforming growth factor beta (1) induces apoptosis in CD34+CD38(-/low) cells that express bcl-2 at a low level显示文摘Xiao M Oppenlander BK Dooley DC 2001Exp Hematol2001,29,9:1
12Singing by male and female Kloss gibbons (Hylobates klossii)in the Peleonan Forest, Sibemt Island, Indonesia 显示文摘Helen M Dooley Debra S 2013Primates2013,54,:1
13Alterations of the medullary ep-ithelial compartment in the Aire-deficient thymus: Implications for programs of thymic epithelial differentiation显示文摘Dooley J Eriekson M Andrew GF 2008J lmmunol2008,181,8:1
14Imaging dynamic redox changes in mammahan ceils with green fluorescent protein indicators显示文摘DOOLEY C T DORE T M HANSON G T 2004JBiol Chem2004,279,22:1
15Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis显示文摘Ginzler E M Dooley M A Aranow C 2005N Engi J Med2005,353,:1
16Mycophenolate mofetilai induction and maintenance therapy fou lupus nephritis:rationale and protocol for the randomized controlled aspreva lupus management suudy显示文摘Sinclair A Appel G Dooley M A 2007Lupus2007,16,:1
17Expression of Smads during in vitro transdifferentiation of hepatic stellate cells to myofibroblasts显示文摘Dooley S Streckert M Delvoux B 2001Biochemical and Biophysical Research Communications2001,283,3:1
18The currency composition of foreign exchange reserves 显示文摘Dooley M P Lizondo S Mathieson D 1989International Monetary Fund1989,36,2:1
19Supply networks and complex adaptive systems:Control ver- sus emergence 显示文摘Choi T Y Dooley K J Rungtusanatham M 2001Journal of Operations Manage- ment2001,19,3:1
20Smad7 dependent expression signature highlights BMP2 and HK2 signaling in HSC transdifferentiation显示文摘AIM: To analyse the influence of Smad7, antagonist of transforming growth factor (TGF)-β canonical signaling pathways on hepatic stellate cell (HSC) transdifferentia-tion in detail. METHODS: We systematically analysed genes regulated by TGF-β/Smad7 in activated HSCs by microarray analy-sis and validated the results using real time polymerase chain reaction and Western blotting analysis. RESULTS: We identif ied 100 known and unknown tar-gets underlying the regulation of Smad7 expression and delineated 8 gene ontology groups. Hk2, involved in glycolysis, was one of the most downregulated proteins, while BMP2, activator of the Smad1/5/8 pathway, was extremely upregulated by Smad7. However, BMP2 de-pendent Smad1 activation could be inhibited in vitro by Smad7 overexpression in HSCs. CONCLUSION: We conclude (1) the existence of a tight crosstalk of TGF-β and BMP2 pathways in HSCs and (2) a Smad7 dependently decreased sugar metabolism ameliorates HSC activation probably by energy with-drawal.Bernd Denecke Lucia Wickert Loredana Ciuclan Steven Dooley Nadja M Meindl-Beinker Yan Liu 2010World Journal of Gastroenterology2010,16,41:1
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