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| 1 | Genome of Wild Mandarin and Domestication History of Mandarin显示文摘官员(柠檬 reticulata ) 是世界范围的最重要的柠檬庄稼之一。它的驯服被相信发生在华南,它是四几千年的官员耕作的中心之一。我们在 Nanling 区域附近收集了官员的自然野人口并且在附近栽培了 landraces。我们发现柠檬性的酸水平戏剧性地在栽培官员被减少。理解 ? 官员驯服的基因基础,我们 de novo 装配了野官员的一个草稿染色体并且分析了一套 104 个柠檬染色体。我们发现 Mangshan 官员是一种原始类型并且二个独立驯服事件发生了,分别地导致在北方和南方 Nanling 山的二组栽培官员(MD1 和 MD2 ) 。二个瓶颈和有效人口尺寸的二扩大为栽培官员的 MD1 组被识别。然而,在 MD2 组织 ? 在人口尺寸有长、连续的减少。MD1 和 MD2 官员从栽培 pummelo 种类显示出种间的基因渗入的不同模式。我们在官员的驯服期间在选择下面可能在基因在柠檬酸盐内容的规定包含了的 aconitate hydratase (ACO ) 识别了高分叉的一个区域,它是。这研究为现存野官员人口的地理起源提供具体基因证据并且使驯服和官员的进化历史清楚些。 | Lun Wang Fa He Yue Huang Jiaxian He Shuizhi Yang Jiwu Zeng Chongling Deng Xiaolin Jiang Yiwen Fang Shaohua Wen Rangwei Xu Huiwen Yu Xiaoming Yang Guangyan Zhong Chuanwu Chen Xiang Yan Changfu Zhou Hongyan Zhang Zongzhou Xie Robert M. Larkin Xiuxin Deng Qiang Xu | 2018 | Molecular Plant2018，11，8： | 14 |
| 2 | Analytic solution to the magnetotelluric response over anisotropic medium and its discussion显示文摘In the present paper,from the second order partial differential equations for solving the magnetotelluric(MT) fields of general anisotropic medium,we first obtained the second order partial differential equations for some anisotropic media with special conductivity(e.g.diagonal anisotropy,transverse anisotropy,azimuthal anisotropy,etc.) by simplifying the electrical conductivity tensor of anisotropic medium.And then we obtained the analytic solutions to MT fields for the case of transverse and azimuthal anisotropy through converting the conductivity parameter based on that of diagonal anisotropy.We further discussed the influence of the selection of integral limit and step length on precision in solving the analytic solutions for MT fields of isotropic medium.Finally,we presented the MT responses of two transverse and azimuthal anisotropic media as well as some applications of the analytic solutions to MT fields of anisotropic medium. | QIN LinJiang YANG ChangFu CHEN Kun | 2013 | Science China Earth Sciences2013，56，9： | 3 |
| 3 | The key procedures and advancement in microbial communities analysis of DGGE显示文摘Recently,denaturing gradient gel electrophoresis(DGGE)is well established molecular tool in microbial ecology that allows the study of diversity and dynamics of microbial communities.The technique has been gained the preference since reliable, facilitative and inexpensive.In order to promote the DGGE further development and make it become a general analysis technique earlier,the key procedures and the advances in microbial communities analysis of DGGE were introduced in this paper. | ZHANG Ying YANG Changfu WANG Aijie | 2007 | Journal of Northeast Agricultural University(English Edition)2007，14，3： | 2 |
| 4 | Quantitative trait locus mapping of yield and plant height in autotetraploid alfalfa(Medicago sativa L.)显示文摘Alfalfa(Medicago sativa L.)is the most widely grown forage legume crop worldwide.Yield and plant height are important agronomic traits influenced by genetic and environmental factors.The objective of this study was to identify quantitative trait loci(QTL)and molecular markers associated with alfalfa yield and plant height.To understand the genetic basis of these traits,a full-sib F1 population composed of 392 individuals was developed by crossing a low-yielding precocious alfalfa genotype(male parent)with a high-yielding latematuring alfalfa cultivar(female parent).The linkage maps were constructed with 3818 single-nucleotide polymorphism(SNP)markers on 64 linkage groups.QTL for yield and plant height were mapped using phenotypic data for three years.Sixteen QTL associated with yield and plant height were identified on chromosomes 1 to 8.Six QTL explained more than 10%of phenotypic variation,representing major loci controlling yield and plant height.One locus on chromosome 1 controlling yield traits had not been identified in previous studies.Three QTL co-located with other QTL(qyield-1 and qheight-7,qheight-5 and qyield-4,qheight-6,and qyield-6).With further validation,the markers closely linked with these QTL may be used for marker-assisted selection in breeding new alfalfa varieties with high yield. | Fei He Ruicai Long Tiejun Zhang Fan Zhang Zhen Wang Xijiang Yang Xueqian Jiang Changfu Yang Xuxin Zhi Mingna Li Longxi Yu Junmei Kang Qingchuan Yang | 2020 | The Crop Journal2020，8，5： | 1 |
| 5 | Upconversion white-light emitting of Tm 3+ and Er 3+ codoped oxyfluoride and its achieving mechanism显示文摘 | Zhizhou Yu Qibin Yang Changfu Xu Yunxin Liu | 2009 | Materials Research Bulletin2009，，7： | 1 |
| 6 | C-Shaped Slot Serves UWB Antenna 显示文摘 | YANG Tang TIAN Xiaoiian CHEN Changfu | 2012 | Microwaves & RF2012，51，2： | 1 |
| 7 | Two-Horn Antenna Aims at UWB Use 显示文摘 | CHEN Changfu TAIN Xiaojian YANG Tang | 2012 | Microwaves & RF2012，51，4： | 1 |
| 8 | Smart nanoprobe based on two-photon sensitized terbium-carbon dots for dual-mode fluorescence thermometer and antibacterial显示文摘Accurate temperature measurement plays an important role in a variety of industrial processes and scientific researches.In our work,the dual-mode temperature response nanoprobe CDs-Tb-TMPDPA containing a two-photon ligand(4-(2,4,6-trimethoxyphenyl)-pyridine-2,6-dicarboxylic acid,TMPDPA)sensitized Tb3+as a temperature-sensitive unit and carbon dots(CDs)as photothermal reagent and a fluorescence reference unit,have been designed and synthesized.In this system,both the fluorescence intensity ratio and the fluorescence lifetime have a good response to temperature.In additio n,due to the excellent photothermal conversion capability of CDs,photothermal antibacterial ability was also tested.Based on the temperature dependence of the fluorescence and the two-photon excitation characteristics of CDs-Tb-TMPDPA,the nanoprobe can also be used in the anti-counterfeiting.Our finding opens a new prospect for the use of two-photon sensitized dual-mode fluorescence thermometers. | Huicheng Yan Hongyuhang Ni Yiwei Yang Changfu Shan Xiaoxi Yang Xiangkai Li Jing Cao Wenyu Wu Weisheng Liu Yu Tang | 2020 | Chinese Chemical Letters2020，31，7： | 1 |
| 9 | In-situ deposition of apatite layer to protect Mg-based composite fabricated via laser additive manufacturing显示文摘Biodegradable magnesium(Mg) and its alloy show huge potential as temporary bone substitute due to the favorable biocompatibility and mechanical compatibility. However, one issue deserves attention is the too fast degradation. In this work, mesoporous bioglass(MBG)with high pore volume(0.59 cc/g) and huge specific surface area(110.78 m^(2)/g) was synthesized using improved sol-gel method, and introduced into Mg-based composite via laser additive manufacturing. Immersion tests showed that the incorporated MBG served as powerful adsorption sites, which promoted the in-situ deposition of apatite by successively adsorbing Ca2+and HPO42-. Such dense apatite film acted as an efficient protection layer and enhanced the corrosion resistance of Mg matrix, which was proved by the electrochemical impedance spectroscopy measurements. Thereby, Mg based composite showed a significantly decreased degradation rate of 0.31 mm/year. Furthermore,MBG also improved the mechanical properties as well as cell behavior. This work highlighted the advantages of MBG in the fabrication of Mg-based implant with enhanced overall performance for orthopedic application. | Youwen Yang Changfu Lu Lida Shen Zhenyu Zhao Shuping Peng Cijun Shuai | 2023 | Journal of Magnesium and Alloys2023，11，2： | 1 |
| 10 | Intense ultraviolet and blue upconversion emissions in Yb3+-Tm3+ codoped stoichiometric Y7O6 F9 powder显示文摘 | Ma Mo Xu Changfu Yang Liwen | 2011 | Physica B2011，406，17： | 1 |
| 11 | Pure red upconversion emission from Yb 3 Al 5 O 12 phase doped with high Er 3+ concentration显示文摘 | Changfu Xu Qibin Yang Guozhong Ren Yunxin Liu | 2010 | Journal of Alloys and Compounds2010，，1： | 1 |
| 12 | Upconversion luminescence and magnetic properties of ligand-free monodisperse lanthanide doped BaGdF 5 nanocrystals显示文摘 | Changfu Xu Mo Ma Liwen Yang Songjun Zeng Qibin Yang | 2011 | Journal of Luminescence2011，，12： | 1 |
| 13 | Genome Assembly of Alfalfa Cultivar Zhongmu-4 and Identification of SNPs Associated with Agronomic Traits显示文摘Alfalfa(Medicago sativa L.)is the most important legume forage crop worldwide with high nutritional value and yield.For a long time,the breeding of alfalfa was hampered by lacking reliable information on the autotetraploid genome and molecular markers linked to important agronomic traits.We herein reported the de novo assembly of the allele-aware chromosome-level genome of Zhongmu-4,a cultivar widely cultivated in China,and a comprehensive database of genomic variations based on resequencing of 220 germplasms.Approximate 2.74 Gb contigs(N50 of 2.06 Mb),accounting for 88.39%of the estimated genome,were assembled,and 2.56 Gb contigs were anchored to 32 pseudo-chromosomes.A total of 34,922 allelic genes were identified from the allele-aware genome.We observed the expansion of gene families,especially those related to the nitrogen metabolism,and the increase of repetitive elements including transposable elements,which probably resulted in the increase of Zhongmu-4 genome compared with Medicago truncatula.Population structure analysis revealed that the accessions from Asia and South America had relatively lower genetic diversity than those from Europe,suggesting that geography may influence alfalfa genetic divergence during local adaption.Genome-wide association studies identified 101 single nucleotide polymorphisms(SNPs)associated with 27 agronomic traits.Two candidate genes were predicted to be correlated with fall dormancy and salt response.We believe that the alleleaware chromosome-level genome sequence of Zhongmu-4 combined with the resequencing data of the diverse alfalfa germplasms will facilitate genetic research and genomics-assisted breeding in variety improvement of alfalfa. | Ruicai Long Fan Zhang Zhiwu Zhang Mingna Li Lin Chen Xue Wang Wenwen Liu Tiejun Zhang Long-Xi Yu Fei He Xueqian Jiang Xijiang Yang Changfu Yang Zhen Wang Junmei Kang Qingchuan Yang | 2022 | Genomics, Proteomics & Bioinformatics2022，20，1： | 1 |
| 14 | Driving Intentions Identification and Behaviors Prediction in Car Lane Change 显示文摘 | Zong Changfu Yang Xiao Wang Chang | 2009 | Journal of Jilin University (Engineering and Technology Edition)2009，39，： | 1 |
| 15 | Relationship between Microstructure Evolution and the Luminescent Properties of Eu^(3+)-doped Yttrium Aluminum Garnet and Y_2O_3 Nano-powders显示文摘Eu3+-doped yttrium aluminum garnet(YAG) and Y2O3 composite phase nanoparticles were synthesized using a modified hydrothermal method.Sintering was performed at 800℃,which is considerably lower than the sintering temperature used in the conventional method.Y3+ in YAG and Y2O3 was partially substituted with Na+ by adding NaNO3 into the solution during sample synthesis.The microstructures and phase transformation process were characterized through X-ray diffraction,scanning electron microscopy,and transmission electron microscopy.The obtained results verified that the addition of Na+ promoted crystallinity and grain growth of the three phases,namely,Y2O3,Y4AI2O9,and Y3AI5O12.Highly efficient luminescence properties excited by 254 and 365 nm ultraviolet were achieved.In conclusion,the remarkable enhancement of the luminescence intensity with the addition of Na+ should be attributed to grain growth and improvement of crystallinity. | Jie Zhang Yongyi Gao Junjie Xiao Changfu Xu Yunxin Liu Qibin Yang | 2013 | Journal of Materials Science & Technology2013，29，3： | 0 |
| 16 | Function of XAGE-1b gene in metastasis process of adenoid cystic carcinoma显示文摘 | Xing Jun Qin Yang Jielin Zhang Chenping Guan Xiaofeng Sun Changfu | 2008 | 中国口腔颌面外科杂志2008，6，B05： | 0 |
| 17 | The acceleration degradation processes of different aged refuses with the forced aeration for landfill reclamation显示文摘Forced aeration is one of the promising ways to accelerate landfill reclamation,and understanding the relation between aeration rates and waste properties is the prerequisite to implementing forced aeration under the target of energy saving and carbon reduction.In this work,landfill reclamation processes with forced aeration were simulated using aged refuses(ARs)of 1,4,7,10,and 13 disposal years,and the potential of field application was also investigated based on a field project,to identify the degradation rate of organic components,the O_(2)consumption efficiency and their correlations to microbes.It was found that the removal rate of organic matter declined from 20.3%(AR_(1))to 12.6%(AR_(13)),and that biodegradable matter(BDM)decreased from 5.2%to 2.4%at the set aeration rate of 0.12 L O_(2)/kg waste(Dry Matter,DM)/day.A linear relationship between the degradation rate constant(K)of BDM and disposal age(x)was established:K=−0.0002193x+0.0091(R^(2)=0.854),suggesting that BDM might be a suitable indicator to reflect the stabilization of ARs.The cellulose/lignin ratio decrease rate for AR1(18.3%)was much higher than that for AR13(3.1%),while the corresponding humic-acid/fulvic-acid ratio increased from 1.44 to 2.16.The dominant bacteria shifted from Corynebacterium(9.2%),Acinetobacter(6.6%),and Fermentimonas(6.5%),genes related to the decompose of biodegradable organics,to Stenotrophomonas(10.2%)and Clostridiales(3.7%),which were associated with humification.The aeration efficiencies of lab-scale tests were in the range of 5.4–11.8 g BDM/L O_(2)for ARs with disposal ages of 1–13 years,and in situ landfill reclamation,ARs with disposal ages of 10–18 years were around 1.9–8.8 g BDM/L O_(2),as the disposal age decreased.The increased discrepancy was observed in ARs at the lab-scale and field scale,indicating that the forced aeration rate should be adjusted based on ARs and the unit compartment combined,to reduce the operation cost. | Yihang Liu Chengqi Ning Qiujie Huang Zhaowen Cheng Weihua Cao Xianghui Wang Changfu Yang Hui Liu Jia Song Luochun Wang Ziyang Lou | 2023 | Waste Disposal and Sustainable Energy2023，5，3： | 0 |
| 18 | H3‑T6SS of Pseudomonas aeruginosa PA14 contributes to environmental adaptation via secretion of a biofilm‑promoting effector显示文摘Microbial species often occur in complex communities and exhibit intricate synergistic and antagonistic interactions.To avoid predation and compete for favorable niches,bacteria have evolved specialized protein secretion systems.The type VI secretion system(T6SS)is a versatile secretion system widely distributed among Gram-negative bacteria that translocates effectors into target cells or the extracellular milieu via various physiological processes.Pseudomonas aeruginosa is an opportunistic pathogen responsible for many diseases,and it has three independent T6SSs(H1-,H2-,and H3-T6SS).In this study,we found that the H3-T6SS of highly virulent P.aeruginosa PA14 is negatively regulated by OxyR and OmpR,which are global regulatory proteins of bacterial oxidative and acid stress.In addition,we identified a H3-T6SS effector PA14_33970,which is located upstream of VgrG3.PA14_33970 interacted directly with VgrG3 and translocated into host cells.Moreover,we found that H3-T6SS and PA14_33970 play crucial roles in oxidative,acid,and osmotic stress resistance,as well as in motility and biofilm formation.PA14_33970 was identified as a new T6SS effec-tor promoting biofilm formation and thus named TepB.Furthermore,we found that TepB contributes to the virulence of P.aeruginosa PA14 toward Caenorhabditis elegans.Overall,our study indicates that H3-T6SS and its biofilm-promot-ing effector TepB are regulated by OxyR and OmpR,both of which are important for adaptation of P.aeruginosa PA14 to multiple stressors,providing insights into the regulatory mechanisms and roles of T6SSs in P.aeruginosa. | Yantao Yang Damin Pan Yanan Tang Jiali Li Kaixiang Zhu Zonglan Yu Lingfang Zhu Yao Wang Peng Chen Changfu Li | 2022 | Stress Biology2022，2，1： | 0 |
| 19 | Analytic Solution to the MT Responses of a Two-Segment Model with Axially Anisotropic Conductivity Structures Overlying a Perfect Insulator显示文摘The analytic solution of the magnetotelluric fields for an idealized 2-D model which is composed of two segments with diagonal anisotropy underlain by aperfect insulator basement is considered using aquasi-static analytic approach.The analytic magnetotelluric responses for a particular model are presented.The resulting analytic solution could be used to check the numerical solutions given by numerical algorithms before more complex situations are investigated. | Qin Linjiang Yang Changfu | 2016 | 吉林大学学报(地球科学版)2016，46，4： | 0 |
| 20 | IGF2BP3-induced activation of EIF5B contributes to progression of hepatocellular carcinoma cells显示文摘In this study,we investigated the functional role of eukaryotic initiation factor 5B(EIF5B)in hepatocellular carcinoma(HCC)and the underlying mechanisms.Bioinformatics analysis demonstrated that the EIF5B transcript and protein levels as well as the EIF5Bcopy number were significantly higher in the HCC tissues compared with the non-cancerous liver tissues.Down-regulation of EIF5B significantly decreased proliferation and invasiveness of the HCC cells.Furthermore,EIF5B knockdown suppressed epithelial-mesenchymal transition(EMT)and the cancer stem cell(CSC)phenotype.Down-regulation of EIF5B also increased the sensitivity of HCC cells to 5-fluorouracil(5-FU).In the HCC cells,activation of the NF-kappa B signaling pathway and IkB phosphorylation was significantly reduced by EIF5B silencing.IGF2BP3 increased the stability of the EIF5B mRNA in an m6A-dependent manner.Our data suggested that EIF5B is a promising prognostic biomarker and therapeutic target in HCC. | XIAOYIN LI QIAN WANG HONGFENG LIANG SHISHENG CHEN HAIWEN CHEN YAOYONG LU CHANGFU YANG | 2022 | Oncology Research2022，30，2： | 0 |
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