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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | 百乐锌与氧化锌的比较试验:减少猪饲粮中的锌添加量同时维持猪的生长性能显示文摘猪的饲料原料通常含有适量浓度的锌(Zn)似乎可以满足猪对Zn的需要。研究证实,高浓度饲粮锌能刺激保育猪的生长和改善饲料利用率。但是,近年来养殖业日渐意识到饲粮中高浓度的矿物质会引起环境问题。人们也日益关注使用有机微量元素作为一种减少矿物质添加量和排泄量的方法。Wedekind(1990,1992)的试验表明,与硫酸锌(100%)相比,蛋氨酸锌(Zn—Met)的生物学效价在117%~206%。 | Carlson M S Veum T L 汪静霞 | 2007 | 养猪2007，，3： | 2 |
| 3 | Modeling and control of magnetorheological dampers forseismic response reduction 显示文摘 | DYKE S J SPENCER B F SAIN M K CARLSON J D | 1996 | Smart Materials and Structures1996，5，5： | 2 |
| 4 | Evidence that physiLologic levels of circulating estrogens and neonatal sex-imprinting modify postpubertal hepatic microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase acivity显示文摘 | Carlson S E Mitchell A D Carter M L | 1980 | Biochem Biophys Acta1980，633，： | 1 |
| 5 | Construction and initial validation of a multidimensional measure of work - family conflict 显示文摘 | Carlson D S Kacmar K M Williams L J | 2000 | Journal of Vocational Behavior2000，56，2： | 1 |
| 6 | Coping with Multiple Dimensions of Work-family Conflict 显示文摘 | Rotondo D M Carlson D S Kincaid J F | 2003 | Personnel Review2003，32，3： | 1 |
| 7 | Isolation and structure of higher diamondoids,nanometer-sized diamond molecules显示文摘 | Dahl J E Liu S G Carlson R M K | 2003 | Science2003，299，5603： | 1 |
| 8 | PAF antagonist treatment reduces pro- inflammatory cytokine mRNA after spinal cord injury 显示文摘 | Hostettler M E Carlson S L | 2002 | Neuroreport2002，13，1： | 1 |
| 9 | Bisphenol A is released from polycarbonate drinking bottles and mimics the neurotoxic actions of estrogen in developing cerebellar neurons 显示文摘 | Le H H Carlson E M Chua J P Belcher S M | 2008 | Toxicology Letters2008，176，2： | 1 |
| 10 | Radiculopathy and myelopathy at segments adjacent to the site of a previous anteri- or cervical arthrodesis显示文摘 | Hilibrand A S Carlson G D Palumbo M A | 1999 | J Bone Joint Surg Am1999，81，4： | 1 |
| 11 | Early and traditionaUy weaned nursery pigs benefit from phase-feeding pharmacological concentration and mineral concen- trations显示文摘 | Carlson M S Hill G M Link J K | 1999 | J Anim Sci1999，77，： | 1 |
| 12 | Radiculopathy and myelopathy at segments adjacent to the site of a previous anterior cervical arthrodesis显示文摘 | Hilibrand A S Carlson G D Palumbo M A | 1999 | J Bone Joint Surg Am1999，81，4： | 1 |
| 13 | Phenomenological model of a magnetorheological damper 显示文摘 | Spencer B F Dyke S J Sain M K Carlson J D | 1997 | Journal of Engineering Mechanics1997，123，3： | 1 |
| 14 | The Fallout from Abusive Supervision : An Examination of Subordinates and Their Partners 显示文摘 | CARLSON D S FERGUSON M PERREWE P L | 2011 | Personnel Psychology2011，64，4： | 1 |
| 15 | Exposure-response(safety)analysis to identify linifanib dose for a Phase III study in patients with hepatocellular carcinoma显示文摘 | Chiu Y L Carlson D M Pradhan R S | 2013 | Clin Ther2013，35，11： | 1 |
| 16 | Construction and initial validation of a multidimensional measure of work-family conflict显示文摘 | Carlson S D Kaoman K M Willianus Ld | 2000 | dournal of Vacational Behavior2000，，9： | 1 |
| 17 | Regulatory Focus as a Mediator of the Influ- ence of Initiating Structure and Servant Leadership on Employee Behavior显示文摘 | NEUBERT M J KACMAR K M CARLSON D S | 2008 | Journal of Applied Psy- chology2008，93，6： | 1 |
| 18 | Evaluation of various inclusion rates of organic zinc either as polysaccharide or proteinate complex on the growth performance,plasma and excretion of nursery pigs显示文摘 | Carlson M S Borea C A Wu C | 2004 | J Anim Sci2004，82，： | 1 |
| 19 | Predicting human brain activity associated with the meanings of nouns 显示文摘 | MITCHELL T M SHINKAREVA S V CARLSON A | 2008 | Science2008，320，5880： | 1 |
| 20 | Copper proteinate in weanling pig diets for enhancing growth performance and reducing fecal copper excretion compared with copper sulfate显示文摘 | Veum T L Carlson M S Wu C W | 2004 | J Anim Sci2004，82，4： | 1 |
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