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| 1 | Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial显示文摘 | Martijn HGM van der Pas Eva Haglind Miguel A Cuesta Alois Fürst Antonio M Lacy Wim CJ Hop Hendrik Jaap Bonjer | 2013 | Lancet Oncology2013，，： | 17 |
| 2 | Minimally invasive versus open oesophagectomy for patients with oesophageal cancer: a multicentre, open-label, randomised controlled trial显示文摘 | Surya SAY Biere Mark I van Berge Henegouwen Kirsten W Maas Luigi Bonavina Camiel Rosman Josep Roig Garcia Suzanne S Gisbertz Jean HG Klinkenbijl Markus W Hollmann Elly SM de Lange H Jaap Bonjer Donald L van der Peet Miguel A Cuesta | 2012 | The Lancet . 2012 (9829)2012，，： | 3 |
| 3 | Hepatocellular carcinoma and multidrug resistance: Past, present and new challenges for therapy improvement显示文摘Hepatocellular carcinoma(HCC) is the most frequent form of liver cancer and the third most common cause of cancer-related death in the world. The main risk factor worldwide for this type of malignancy is chronic hepatitis caused by hepatitis B virus and hepatitis C virus infections. Advances in early detection and treatmenthave improved life expectancy of patients with HCC. However, this disorder remains as a disease with poor prognosis. In fact, epidemiological studies have revealed that there is an 8-mo median survival rate in patients, approximately 20% of whom survive one year while only 5% remain alive after three years. Additionally, HCC is particularly difficult to treat because of its high recurrence rate, and its resistance to conventional chemotherapy is due, among other mechanisms, to several members of the ATP-Binding Cassette protein family involved in drug transport being overexpressed. Fortunately, there is evidence that these patients may benefit from alternative molecular-targeted therapies. This manuscript intends to provide further insight into the etiology and molecular mechanisms related to HCC development and the latest therapeutic approaches to treat this malignancy. The development of effective delivery systems of antitumor drugs able to target the liver parenchyma is also assessed. Finally, the prospects in the development of more efficient drug therapies to overcome multidrug resistance are also examined. | María L Cuestas José R Oubia Verónica L Mathet | 2015 | World Journal of Pharmacology2015，4，1： | 2 |
| 4 | Simplified R-factor relationships for strong ground motions显示文摘 | Cuesta I Aschheim A Fajfar P | 2003 | Earthquake Spectra2003，19，1： | 1 |
| 5 | Microperforated insertion units: An alternative strategy to design microperforated panels显示文摘 | Jaime Pfretzschner Pedro Cobo Francisco Simón María Cuesta Alejandro Fernández | 2005 | Applied Acoustics2005，，1： | 1 |
| 6 | Neonatal diabetes mellitus due to complete glucokinase deficiency 显示文摘 | Njolstad P R Sovik O Cuesta M A | 2001 | N Engl J Med2001，344，： | 1 |
| 7 | Single- incision versus conventional laparoscopic cholecystectomy: a case control study 显示文摘 | van den Boezem P B Kruyt P M Cuesta M A | 2012 | Acta Chir Belg2012，112，5： | 1 |
| 8 | Flow injection method for the rapid determination of chemical oxygen de- mand based on microwave digestion and chromium speci- ation in flame atomic absorption spectrometry 显示文摘 | CUESTA A TODO L J L CANALS A | 1996 | Spec- trochim Acta Part B1996，51，14： | 1 |
| 9 | Use of gene therapy in a subcutaneous murine model of lung cancer 显示文摘 | Rodrigo Garzon M Tirapu Femondez de la Cuesta I Arina Iraeta A | 2006 | Arch Bronconeumol2006，42，10： | 1 |
| 10 | Quantitation and distribution of polar compounds in an ex- tra virgin olive oil and used in fryings with turnover of fresh oil 显示文摘 | ROMERO A CUESTA C SANCHEZ - MUNIZ F J | 1995 | Eur J Lipid Sci Tech1995，97，11： | 1 |
| 11 | Dietary administration of Lactobacill delbrueckii and Bacillus subtilis,single or combined,on gilthead seabream cellular innate immune responses显示文摘 | Salinas I Cuesta A Esteban M A | 2005 | Fish andShellfish Immunology2005，19，1： | 1 |
| 12 | Minimally invasive versus open oesophagectomy for patients with oesophageal cancer: a multicentre, open-label, randomised controlled trial显示文摘 | Surya SAY Biere Mark I van Berge Henegouwen Kirsten W Maas Luigi Bonavina Camiel Rosman Josep Roig Garcia Suzanne S Gisbertz Jean HG Klinkenbijl Markus W Hollmann Elly SM de Lange H Jaap Bonjer Donald L van der Peet Miguel A Cuesta | 2012 | The Lancet2012，，9829： | 1 |
| 13 | Thermal behaviour during the pyrolysis of low rank perhydrous coals显示文摘 | A Arenillas F Rubiera J.J Pis M.J Cuesta M.J Iglesias A Jiménez I Suárez-Ruiz | 2003 | Journal of Analytical and Applied Pyrolysis2003，，： | 1 |
| 14 | Dietary administration of Lactobaeillus del- bmeckii and Bacillus subtilis,single or combined, on gilthead seabream cellular innate immune responses显示文摘 | Salinas I Cuesta A Esteban M | 2005 | Fish Shellfish Immunol2005，19，： | 1 |
| 15 | Level ground and uphill cycling ability in professional road cycling显示文摘 | PADILLA A MUJIKA I CUESTA G et a l | 1999 | Med Sci Sport Exe1999，31，： | 1 |
| 16 | Press archives as temporal records of landslides in the North of Spain: relationships between rainfall and instability slope events显示文摘 | Cuesta M J Sanchez M J Garcia A R | 1999 | Geomorphology1999，30，： | 1 |
| 17 | Organochlorine and heavy metal residues in the water/sediment system of the Southeast Regional Park in Madrid, Spain显示文摘 | Fernandez M Cuesta S Jimenez O Garcia M A Hernandez L M Marina M L Gonzalez M J | 2000 | Chemosphere2000，41，： | 1 |
| 18 | Phase transition in two-dimensional traffic model显示文摘 | Cuesta J A Martinez F C Molerea J M | 1993 | Phys Rev1993，48，6： | 1 |
| 19 | Molecular and functional characterization of the gilthead seabream Ⅱ-defensin demonstrate its chemotactic andantimicrobial activity显示文摘 | CUESTA A MESEGUER J ESTEBAN M A | 2011 | Mol Immunoh2011，48，1213： | 1 |
| 20 | Minimally invasive versus open esophagectomy for cance: a systematic review and meta-analysis显示文摘 | Biere S S Cuesta M A Vander D L | 2009 | Minerva Chirurgica2009，64，2： | 1 |
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