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| 1 | Targeting Gut Microbiota Dysbiosis: Potential Intervention Strategies for Neurological Disorders显示文摘It is well known that the gut microbiota plays an extremely important role in modulating host physiological functions such as immunity and metabolic homeostasis.In recent years,accumulated evidence has revealed that the gut microbiota can regulate the functions of the central nervous system(CNS)through the gut-brain axis,which provides a novel insight into the interactions between the gut and brain.This review focuses on the molecular mechanism of the crosstalk between the gut microbiota and the brain via the gut-brain axis,and on the onset and development of neurological disorders triggered by gut microbiota dysbiosis.These topics are followed by a critical analysis of potential intervention strategies targeting gut microbiota dysbiosis,including the use of probiotics,prebiotics,synbiotics,and diets.While research on the microbiota-gut-brain axis is still in its relative infancy,clarifying the molecular mechanism that underlies how the gut microbiota regulates neurological functions not only holds the promise of revealing potentially novel pathogeneses of neurological disorders,but also may lead to the development of potential diagnosis biomarkers and intervention strategies targeting microbiota dysbiosis for neurological disorders. | Wanqiang Wu Qingmin Kong Peijun Tian Qixiao Zhai Gang Wang Xiaoming Liu Jianxin Zhao Hao Zhang Yuan Kun Lee Wei Chen a | 2020 | Engineering2020，6，4： | 7 |
| 2 | Experimental demonstration of ultra-large-scale terahertz all-dielectric metamaterials显示文摘All-dielectric metamaterials have emerged as a promising platform for low-loss and highly efficient terahertz devices. However, existing fabrication methods have difficulty in achieving a good balance between precision and cost. Here, inspired by the nano-template-assisted self-assembly method, we develop a micro-templateassisted self-assembly(MTAS) method to prepare large-scale, high-precision, and flexible ceramic microsphere all-dielectric metamaterials with an area exceeding 900 cm × 900 cm. Free from organic solvents, vacuum, and complex equipment, the MTAS method ensures low-cost and environmentally friendly fabrication. The ceramic microsphere resonators can be readily assembled into nearly arbitrary arrangements and complex aggregates, such as dimers, trimers, quadrumers, and chains. Finally, using the heat-shrinkable substrate and dipole coupling effect, a broadband reflector with a bandwidth of 0.15 THz and a reflection of up to 95% is demonstrated.This work provides a versatile and powerful platform for terahertz all-dielectric metamaterials, with potential to be applied in a wide variety of high-efficiency terahertz devices. | KE BI DAQUAN YANG JIA CHEN QINGMIN WANG HONGYA WU CHUWEN LAN YUPING YANG | 2019 | Photonics Research2019，7，4： | 5 |
| 3 | Compositions of aliphatic des-A-triterpenes in the Hani peat deposit,Northeast China and its biological significance显示文摘Aliphatic des-A-triterpenes,the degradation products of pentacyclic triterpenes have been tentatively assigned in samples taken from a 963-cm-thick peat sequence from the Hani region of Northeast China using gas chromatography-mass spectrometry(GC-MS)in order to understand and identify these des-A-triterpenes response to climate and ecology.The study indicates that aliphatic des-A-triterpenes are abundant in the Hani peat bog.The high relative abundance of the total des-A-triterpenes mainly occurs at the Holocene periods and is corresponding to the low sedimentation rate.The mechanism of des-A-triterpenes accumulation is not consistent with the previous studies.It is proposed that the biological community is also one influence factor.The obvious stage variations of the total des-A-triterpenes in the whole sequence reveal the different biological(microbes and plants) processes and responses,possibly revealing the four large replacements of biological community and functional composition in the swamp environment over the 16000 cal a BP.The low total des-A-triterpenes values occur at about 10200,8700,7700,6600,4480-3940 and 3040 cal a BP,reflecting the multiple millennial micro-environment oscillations under the macro-environment of the swamp during the Holocene.The ratios of diene and monoene des-A-triterpenes(DT/MT),des-A-lupane and diene and monoene des-A-triterpenes(DL/(DT+MT)),ratios ofindividual compounds exhibit vertical opposite to the total des-A-triterpenes. Namely,these ratios are high during the last deglaciation and late Holocene whereas they are low at other periods,indicating different compounds have different responses to micro-environment and microbial activities.This study discusses the diversity of biological community and biological functional composition response to micro-environment,which not only provides the complement in Northeast China,but also bears important fundamental information for the implication to ecological environment in the future. | ZHENG YanHong ZHOU WeiJian LIU Zhao CHEN QingMin YU XueFeng LIU XiaoMin | 2010 | Chinese Science Bulletin2010，55，21： | 5 |
| 4 | A novel non-precious metal catalyst synthesized via pyrolysis of polyaniline-coated tungsten carbide particles for oxygen reduction reaction显示文摘 | Kezhu Jiang Qingmin Jia Mingli Xu Daping Wu Lunquan Yang Guotao Yang Linyan Chen Guanghua Wang Xikun Yang | 2012 | Journal of Power Sources2012，，： | 1 |
| 5 | The C_(6)D_(6)detector system on the Back-n beam line of CSNS显示文摘Introduction The neutron capture cross sections are very important in the field of nuclear device design and basic physics research.Hydrogen-free liquid scintillator such as C_(6)D_(6)detectors are widely used in the neutron capture cross-sectional measurements for the low neutron sensitivity and fast time response.The Back-n white neutron source at China Spallation Neutron Source is the first spallation white neutron source in China,and it is suitable for neutron capture cross-sectional measurement.Materials and methods A C_(6)D_(6)detector system was built in the Back-n experimental station.The pulse height weighting technique was used to determine the system’s detection efficiency.The response to gamma rays of the C_(6)D_(6)detector was measured,and the energy resolution function was determined.Monte Carlo simulation with Geant4 code was carried out to get the weighting function of this C_(6)D_(6)detector system.Additionally,the systematic uncertainty of the weighting function was also determined.Conclusion According to the experimental and simulation results,this C_(6)D_(6)detector system can be used to measure neutron capture cross section. | Jie Ren Xichao Ruan Jie Bao Guangyuan Luan Wei Jiang Qi An Huaiyong Bai Ping Cao Qiping Chen Yonghao Chen Pinjing Cheng Zengqi Cui Ruirui Fan Changqing Feng Minhao Gu Fengqin Guo Changcai Han Zijie Han Guozhu He Yongcheng He Yuefeng He Hanxiong Huang Weiling Huang Xiru Huang Xiaolu Ji Xuyang Ji Haoyu Jiang Hantao Jing Ling Kang Mingtao Kang Bo Li Lun Li Qiang Li Xiao Li Yang Li Yang Li Rong Liu Shubin Liu Xingyan Liu Yinglin Ma Changjun Ning Binbin Qi Zhaohui Song Hong Sun Xiaoyang Sun Zhijia Sun Zhixin Tan Hongqing Tang Jingyu Tang Pengcheng Wang Qi Wang Taofeng Wang Yanfeng Wang Zhaohui Wang Zheng Wang Jie Wen Zhongwei Wen Qingbiao Wu Xiaoguang Wu Xuan Wu Likun Xie Yiwei Yang Han Yi Li Yu Tao Yu Yongji Yu Guohui Zhang Jing Zhang Linhao Zhang Liying Zhang Qingmin Zhang Qiwei Zhang Xianpeng Zhang Yuliang Zhang Zhiyong Zhang Yingtan Zhao Liang Zhou Zuying Zhou Danyang Zhu Kejun Zhu Peng Zhu | 2019 | Radiation Detection Technology and Methods2019，3，3： | 1 |
| 6 | Fabrication of an optically transparent super-hydrophobic surface via embedding nano-silica显示文摘 | CHEN QINGMIN SU CHANGHONG LI JUN | 2006 | Applied surface science2006，25，5： | 1 |
| 7 | Synthesis and properties of polyurethane modify with aminoethylaminopropyl poly(dimethyl siloxane)显示文摘 | Fan Quli Fang Jianglin Chen Qingmin | 1999 | Journal of Applied Polymer Science1999，74，25： | 1 |
| 8 | CpG oligodeoxynucleotide induces bone marrow precursor cells into myeloid-derivedsuppressor cells显示文摘 | Jie Chen Chengyu Deng Qingmin Shi Jun Jiang Yongbo Zhang Wei Shan Weimin Sun | 2013 | Molecular Medicine Reports2013，，4： | 1 |
| 9 | 显示文摘 | Chen Qingmin Oe Hanhua | 1994 | 54(9): 1191-11971994，54，9： | 1 |
| 10 | The preparation technology and its application on the super-hydrophobic surface显示文摘 | Wang Qingjun Chen Qingmin | 2005 | Molecular Materials of Science and Engineering2005，21，2： | 1 |
| 11 | A novel non-precious metal catalyst synthesized via pyrolysis of polyaniline-coated tungsten carbide particles for oxygen reduction reaction显示文摘 | Kezhu Jiang Qingmin Jia Mingli Xu Daping Wu Lunquan Yang Guotao Yang Linyan Chen Guanghua Wang Xikun Yang | 2012 | Journal of Power Sources2012，，： | 1 |
| 12 | Stable highly hydrophobic and oleophilic meshes for oil–water separation显示文摘 | Qingjun Wang Zhe Cui Yi Xiao Qingmin Chen | 2007 | Applied Surface Science2007，，23： | 1 |
| 13 | Effects of nitrate on intracel|ular nitrite and growth of mierocystis aeruginosa 显示文摘 | CHEN Weimin ZHANG Qingmin DAI Shugui | 2009 | Journal of Applied Phycology2009，21，6： | 1 |
| 14 | Effect of Loading Rate on Low-cycle Fatigue Properties of Turbine Rotor Steel显示文摘 | Jianjun He Jian Chen Qingmin Sun | 2014 | Procedia Materials Science2014，，： | 1 |
| 15 | Investigation on Damping Behavior and Morphology of Polyurethane/Polymethacrylates and Polyacrylates Interpenetrating Polymer Networks显示文摘 | Qingmin Chen Hanhua Ge | 1994 | Journal of Applied Polymer Science1994，54，9： | 1 |
| 16 | Synthesis and SAR studies of phenanthroindolizidine and phenanthroquinolizidine alkaloids as potent anti-tumor agents显示文摘 | Ziwen Wang Meng Wu Yi Wang Zheng Li Lei Wang Guifang Han Fazhong Chen Yuxiu Liu Kailiang Wang Ao Zhang Linghua Meng Qingmin Wang | 2012 | European Journal of Medicinal Chemistry2012，，： | 1 |
| 17 | Synthesis and properties of polyurethane modified with aminoethyl- aminopropyl poly(dimethyl siloxane) 显示文摘 | FAN Quli FANG Jianglin CHEN Qingmin | 1999 | Journal of Applied Polymer Seience1999，74，10： | 1 |
| 18 | Effect of nitrite on growth and microcystis production of microcystis aeruginosa PCC7806 显示文摘 | CHEN Weimin LIU Hao ZHANG Qingmin | 2011 | Journal of Applied Phycology2011，23，： | 1 |
| 19 | Transfer model and kinetic characteristics of $${\rm NH}_{4}^{+}$$ –K+ ion exchange on K-zeolite显示文摘 | Junsheng Yuan Qingmin Chen Jingkang Wang | 2008 | Transport in Porous Media2008，，1： | 1 |
| 20 | Transfer model and kinetic characteristics of NH4^+-K^+ ion exchange on K-zeolite显示文摘 | Yuan Junsheng Chen Qingmin Wang Jingkang | 2008 | Transport in Porous Media2008，72，1： | 1 |
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