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| 1 | Liver bioengineering:Current status and future perspectives显示文摘The present review aims to illustrate the strategies that are being implemented to regenerate or bioengineer livers for clinical purposes.There are two general pathways to liver bioengineering and regeneration.The first consists of creating a supporting scaffold,either synthetically or by decellularization of human or animal organs,and seeding cells on the scaffold,where they will mature either in bioreactors or in vivo.This strategy seems to offer the quickest route to clinical translation,as demonstrated by the development of liver organoids from rodent livers which were repopulated with organ specific cells of animal and/or human origin.Liver bioengineering has potential for transplantation and for toxicity testing during preclinical drug development.The second possibility is to induce liver regeneration of dead or resected tissue by manipulating cell pathways.In fact,it is well known that the liver has peculiar regenerative potential which allows hepatocyte hyperplasia after amputation of liver volume.Infusion of autologous bone marrow cells,which aids in liver regeneration,into patients was shown to be safe and to improve their clinical condition,but the specific cells responsible for liver regeneration have not yet been determined and the underlying mechanisms remain largely unknown.A complete understanding of the cell pathways and dynamics and of the functioning of liver stem cell niche is necessary for the clinical translation of regenerative medicine strategies.As well,it will be crucial to elucidate the mechanisms through which cells interact with the extracellular matrix,and how this latter supports and drives cell fate. | Christopher Booth Tom Soker Pedro Baptista Christina L Ross Shay Soker Umar Farooq Robert J Stratta Giuseppe Orlando | 2012 | World Journal of Gastroenterology2012，18，47： | 2 |
| 2 | Human plasma carotenoid response to the ingestion of controlled diets high in fruits and vegetables显示文摘 | YEUM K J BOOTH S L SADOWSKI J A | 1996 | Am J Clini Nutr1996，64，4： | 1 |
| 3 | Development of Numerical Estimation in Young Children 显示文摘 | Siegler R S Booth J L | 2004 | Child Development2004，，75： | 1 |
| 4 | Development of numerical estimation in young children 显示文摘 | Siegler R S & Booth J L | 2004 | Child Development2004，75，： | 1 |
| 5 | A comparative study of the characteristics of fibre-flax (Linum usitatissimum)显示文摘 | Booth I Harwood R J Wyatt J L | 2004 | Industrial Crops and Products2004，20，1： | 1 |
| 6 | Continuum percolation and geometry of wireless networks显示文摘 | BOOTH L BRUCK J FRANCESCHETTI M | 2003 | Annals of Applied Probability2003，13，2： | 1 |
| 7 | Graphene-based liquid crystal device 显示文摘 | BLAKE P BRIMICOMBE P D NAIR R R BOOTH T J JIANG D SCHEDIN F PONOMARENKO L A MOROZOV S V GLEESON H F HILL E W GEIM A K NOVOSELOV K S | 2008 | Nano Letters2008，8，6： | 1 |
| 8 | HDAC inhibitors enhance the lethality of low dose salinomycin in parental and stem-like GBM cells显示文摘 | BOOTH L ROBERTS J L CONLEY A | 2014 | Cancer Biol Ther2014，15，3： | 1 |
| 9 | Promoting physical activity participation among children and adolescents显示文摘 | Salmon J Booth M L Phongsavan P | 2007 | Epidem Rev2007，29，1： | 1 |
| 10 | Estimating the economic impact of a short-term tourist event 显示文摘 | Bitta A J Loudon D L Booth G G Weeks R R | 1977 | Journal of Travel Research1977，16，2： | 1 |
| 11 | Ownership Dispersion, Costly Information, and IPO Underpricing显示文摘 | Booth J R Smith R L | 1996 | Journal of Financial Economics1996，，2： | 1 |
| 12 | Production of biologically active hirudin in plant seeds using oleosin partitioning 显示文摘 | Parmenter D L Boothe J G Moloney M M | 1995 | Plant Molecular Biology1995，29，6： | 1 |
| 13 | Estimating the economic impact of a short-term tourist event 显示文摘 | Della B A J Loudon D L Booth G G Weeks R R(1977) | 1977 | Journal of Travel Research1977，16，2： | 1 |
| 14 | Ownership dispersion, costly information, and IPO underpricing显示文摘 | Booth J R Chua L | 1996 | Journal of Financial Economics1996，，41： | 1 |
| 15 | Molecular recognition in cyclodextrin complexes of amino acid derivatives(2) A new perturbation:the room-temperature crystallographic structure determination for the N-Acetyl-p-methoxy-l-phenylalanine methyl ester/b-cyelodextrin complex显示文摘 | Clark J L Booth B R Stezowski J J | 2001 | J Amer Chem Soc2001，123，40： | 1 |
| 16 | Human thrombi contain an abundance of active thrombin显示文摘 | MUTCH N J ROBBIE L A BOOTH N A | 2001 | Thromb Haemost2001，86，： | 1 |
| 17 | Nitric oxide donors: biochemical pharmacology and therapeutics 显示文摘 | BAUER J A BOOTH B P FUNG H L | 1995 | Adv Pharmacol1995，34，： | 1 |
| 18 | Production of biologically active hirudin in plant seeds using oleosin partitioning显示文摘 | PARMENTER D L BOOTHE J G ROOIJEN G J H | 1995 | Plant Molecular Biology1995，29，： | 1 |
| 19 | Capital raising, underwriting and the certification hypothesis显示文摘 | Booth J R Smith R L | 1986 | Journal of Financial Economics1986，15，12： | 1 |
| 20 | Capital raising,underwriting and the certification hypothesis显示文摘 | Booth J R Smith R L | 1986 | Journal of Financial Economics1986，15，12： | 1 |
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