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3篇 您的检索式:作者名="Beiping Miao"
    题名 作者 年代 出处 被引量
1Transcription factor TFE3 enhances cell cycle and cancer progression by binding to the hTERT promoter显示文摘Dear Editor,Telomeres are located at the ends of chromosomes and are essential for chromosome stability and replication.They progressively get shorter with cell division,eventually resulting in cell proliferation arrest.The process is considered a barrier to tumor occurrence[1,2].Abnormally activated telomerase with constitutive telomerase reverse transcriptase(TERT)expression is a hallmark of almost all human tumors[3].Some genomic alterations in the human TERT(hTERT)promoter are associated with activation of hTERT transcription in various cancer types[4].Beiping Miao Chaoyang Zhang Nadine Stroh Lukas Brenner Katrin Hufnagel Jörg DHoheisel Obul Reddy Bandapalli 2021Cancer Communications2021,41,12:1
2Black phosphorus quantum dots as multifunctional nanozymes for tumor photothermal/catalytic synergistic therapy显示文摘Nanozymes are nanomaterials with enzyme-like properties that have attracted significant interest owing to their high stability,easy preparation,and tunable catalytic properties,especially in the field of cancer therapy.However,the unfavorable catalytic effects of nanozymes in the acidic tumor microenvironment have limited their applications.Herein,we developed a biomimetic erythrocyte membrane-camouflaged ultrasmall black phosphorus quantum dots(BPQDs)nanozymes that simultaneously exhibited an exceptional near-infrared(NIR)photothermal property and dramatically photothermal-enhanced glucose oxidase(GOx)-like activity in the acidic tumor microenvironment.We demonstrated the engineered BPQDs gave a photothermal conversion efficiency of 28.9%that could rapidly heat the tumor up to 50℃ while effectively localized into tumors via homing peptide iRGD leading after intravenously injection.Meanwhile,the significantly enhanced GOx-like activity of BPQDs under NIR irradiation was capable of catalytical generating massive toxic reactive oxygen species via using cellular glucose.By combining the intrinsic photothermal property and the unique photothermal-enhanced GOx-like catalytic activity,the developed BPQDs were demonstrated to be an effective therapeutic strategy for inhibiting tumor growth in vivo.We believe that this work will provide a novel perspective for the development of nanozymes in tumor catalytic therapy.Hui Ding Daji Wang Haibing Huang Xiaozhu Chen Jie Wang Jinjie Sun Jianlin Zhang Lu Lu Beiping Miao Yanjuan Cai Kelong Fan Yongtian Lu Hongsong Dong Xiyun Yan Guohui Nie Minmin Liang 2022Nano Research2022,15,2:1
3Erratum to:Black phosphorus quantum dots as multifunctional nanozymes for tumor photothermal/catalytic synergistic therapy显示文摘Erratum to Nano Research 2022,15(2):1554–1563 http://gffzzd3cc09b8251d45dfsowx5popoqxfk65fp.ffgz.tsg.suse.edu.cn/10.1007/s12274-021-3701-8 Figure 3(d)in the original paper contained duplicated micrographs(BPQDs+NIR)for different xenografts(B16 vs.CNE-2).This error did not affect any of the conclusions from the published paper.Hui Ding Daji Wang Haibing Huang Xiaozhu Chen Jie Wang Jinjie Sun Jianlin Zhang Lu Lu Beiping Miao Yanjuan Cai Kelong Fan Yongtian Lu Hongsong Dong Xiyun Yan Guohui Nie Minmin Liang 2023Nano Research2023,16,1:0
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