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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Effects of Soil Conservation Measures on Erosion Rates and Crop Productivity on Subtropical Ultisols in Yunnan Province,China显示文摘 | BARTON A P FULLEN M A MITCHELL D J | 2004 | Agriculture Ecosystems and Environment2004，104，2： | 1 |
| 3 | Monitoring floods with AVHRR 显示文摘 | Barton I J Bathols J M | 1989 | Remote Sensing of Environment (S0034-4257)1989，30，1： | 1 |
| 4 | Transmission line resistance compression networks and applications to wireless power transfer显示文摘 | BARTON T W GORDONSON J M PERREAULT D J | 2015 | IEEE Journal of Emerging and Selected Topics in Power Electronics2015，3，1： | 1 |
| 5 | Expectant management of severe preeclampsia at 27 (0/7) to 33 ( 6/7 ) weeks gestation : maternal and perinatal outcomes according to gestational age by weeks at onset of expectant management 显示文摘 | BOMBRYS A E BARTON J R HABLI M | 2009 | American Journal of Perinatology2009，26，6： | 1 |
| 6 | Evidence that monoclonal antibodies directed against the integrin β subunit plexin/ semaphorin/integrin domain stimulate function by inducing receptor extension显示文摘 | Mould A P Travis M A Barton S J | 2005 | J Biol Chem2005，280，6： | 1 |
| 7 | Expectant management of severe preeclampsia at 27(0/7) to 33(6/7) weeks' gestation:maternal and perinatal outcomes according to gestational age by weeks at onset of expectant management显示文摘 | Bombrys A E Barton J R Habli M | 2009 | Am J Perinatol2009，26，6： | 1 |
| 8 | Distinct Amygdala-autonomic Arousal Profiles in Response to Fear Signals in Healthy Males and Females显示文摘 | WILLIAMS L M BARTON M J KEMP A H | 2005 | Neuroimage2005，，28： | 1 |
| 9 | MicroRNA control of PHABULOSA in leaf development:importance of pairing to the mieroRNA 5' region 显示文摘 | Mallory A C Reinhart B J Jones-Rhoades M W Tang G L Zamore P D Barton M K Barrel D P | 2004 | The EMBO Journal2004，23，： | 1 |
| 10 | Meehanical Properties of Tough, High Temperature Carbon Fibre Composites from Novel Functionalized Aryl Cyanate Ester Polymers显示文摘 | Barton J M Hamerton 1 Jones J R | 1996 | Polymer1996，37，20： | 1 |
| 11 | Monitoring floods with AVHRR显示文摘 | Barton I J Bathols J M | 1989 | Remote Sensing of E nvironment1989，30，1： | 1 |
| 12 | Monitoring floods with AVttRR显示文摘 | BARTON I J BATHOLS J M | 1989 | Remote Sensing of Environment1989，30，1： | 1 |
| 13 | Probing microstructures in double-helical DNA with chiral metal complexes: recognition of changes in base-pair propeller twisting in solution 显示文摘 | Pyle A M Morii T Barton J K | 1990 | J Am Chem Soc1990，112，25： | 1 |
| 14 | Electrochemical DNA sensors显示文摘 | Drummond T G Hill M G Barton J K | 2003 | Nature Biotechnology2003，21，10： | 1 |
| 15 | Probing DNA charge transport with metallointercalators显示文摘 | Nunez M E BARTON J K | 2000 | Current Opinion in Chemical Biology2000，4，2： | 1 |
| 16 | Science显示文摘 | Murphy C J Arkin M R Jenkins Y Ghatlia N D Bossmann SH Turro N J Barton J K | 1993 | 262:10251993，262，： | 1 |
| 17 | Obesity-asso- ciated activation of angiotensin and endothelin in the cardiovascu- lar system显示文摘 | BARTON M CARMONA R ORTMANN J | 2003 | lnt J Biochem Cell Biol2003，35，6： | 1 |
| 18 | The Cu stockwork and massive sulfide ore of the feitais volcanic-hosted massive sulfide deposit,aljustrel,iberian pyrite belt,portugal: A mineralogical,fluid inclusion,and isotopic investigation显示文摘 | Inverno C M C Solomon M Barton M D Foden J | 2008 | Economic Geology2008，103，： | 1 |
| 19 | Hemochromatosis and iron-overload screening in a racially diverse population 显示文摘 | ADAMS P C REBOUSSIN D M BARTON J C | 2005 | New Engl J Med2005，352，： | 1 |
| 20 | Copy-number variation genotyping of GSTY1 and GSTM1 gene deletions by real- time PCR 显示文摘 | Rose-zerilli M J Barton S J Henderson A J | 2009 | Clin Chem2009，55，9： | 1 |
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