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| 1 | The Role of Fibrocyte in the Pathogenesis of Silicosis显示文摘Exposure to free silica induces silicosis and myofibroblasts are regarded as primary effector cells.Fibrocytes can differentiate into myofibroblast.Therefore,the present study was designed to investigate whether | LI Juan YAO Wu HOU Jian Yong ZHANG Lin BAO Lei CHEN Hui Ting WANG Di YUE Zhong Zheng LI Yi Ping ZHANG Miao YU Xing Hao ZHANG Jian Hui QU Ya Qian HAO Chang Fu | 2018 | Biomedical and Environmental Sciences2018，31，4： | 20 |
| 2 | 5-Methylcytosine RNA Methylation in Arabidopsis Thaliana显示文摘5-Methylcytosine (m 5 C ) 是描绘得好的 DNA 修正,并且主要也在初核质和优核质在丰富的非编码的 RNA 被报导。然而,分发和 m 5 在植物 mRNAs 的 C 仍然保持大部分未知。这里,我们报导 RNA m 5 在由使用 m 5 C RNA immunoprecipitation 由一条深定序的途径列在后面(m 5 C-RIP-seq ) 。LC-MS/MS 和点污点分析揭示 m 5 在各种各样的纸巾并且在不同发展阶段的 C mRNA 修正。m 5 C-RIP-seq 分析识别了 6045 m 5 在 4465 的 C 山峰在年轻幼苗表示了基因。我们发现那 m 5 C 在编码序列,二座山峰在开始 codons 以后并且在站 codons 前立即定位了被充实,并且随低翻译与 mRNAs 被联系活动。我们进一步表明了那 RNA (cytosine-5 )-methyltransferase,tRNA 特定的 methyltransferase 4B (TRM4B ) ,展览 m 5 C RNA methyltransferase 活动。在 TRM4B 的变化在根开发和减少的 m 5 C 山峰。TRM4B 影响涉及根开发的基因的抄本层次,它断然与他们的 mRNA 稳定性和 m 5 C 层次。我们的结果建议那 m 5 在 mRNA 的 C 是新 epitranscriptome 标记 inArabidopsis,并且这修正的那条规定是基因的不可分的部分规章的网络位于 \O 下面植物开发。 | Xuean Cui Zhe Liang Lisha Shen Qian Zhang Shengjie Bao Yuke Geng Bin Zhang Vonny Leo Leah A. Vardy Tiegang Lu Xiaofeng Gu Hao Yu | 2017 | Molecular Plant2017，10，11： | 19 |
| 3 | Clinical and laboratory survey of 65 Chinese patients with Leigh syndrome显示文摘Background Leigh syndrome is an inherited neurodegenerative disease that emerges in infancy and childhood and presents with a clinically heterogeneous variety of neuromuscular and non-neuromuscular disorders. It can result from the inheritance of mutations in either nuclear or mitochondrial DNA. In the current study, we performed a retrospective study in 65 patients in order to investigate the clinical and genetic characteristics of Leigh syndrome in Chinese patients. Methods Sixty-five unrelated cases (35 men and 30 women) who were hospitalized in the past 12 years were reviewed. Diagnosis was based on both the clinical presentation and the characteristic neuropathologic findings of bilateral symmetric necrotizing lesions in the basal ganglia and brain stem as detected using cranial computed tomography (CT) scan or magnetic resonance imaging (MRI). The differential diagnosis of organic acidurias and fatty acid ?-oxidation defects were performed. Specific point mutations and deletions in mitochondrial DNA (T8993G, T8993C, T9176C, A8344G, A3243G) were screened by PCR-restriction analysis and Southern blot. The SURF1 gene was sequenced. Skeletal muscle biopsies were performed in 17 (26.2%) of the patients. The diagnosis was confirmed by autopsy in 6 (9.2%) patients. Results The patients had various forms of metabolic encephalomyopathy. Fifty-nine (90.8%) of the patients had the typical neuroradiological features of Leigh syndrome, including symmetrical necrotizing lesions scattered within the basal ganglia, thalamus and brain stem. Twenty (30.8%) patients were confirmed by genetic, biochemical analysis and autopsy. Specific point mutations in mitochondrial DNA were found in 5 cases (7.7%). Of these, the A8344G mutation was detected in 2 patients. The T8993G, T8993C, and A3243G point mutations were identified in 3 other patients, respectively. SURF1 mutations associated with cytochrome c oxidase deficiency were identified in 8 (12.3%) families by DNA sequencing. A G604C mutation was identified in 6 (9.2%) patients. The genotypes of 52 patients remained unknown. Conclusions Leigh syndrome presents as a diverse array of clinical features and can result from specific mutations in nuclear or mitochondrial DNA. In this study, SURF1 mutations associated with cytochrome c oxidase deficiency were identified in 8 (12.3%) out of 65 patients with Leigh syndrome. It indicates that SURF1 mutations might be a common cause of Leigh syndrome in China. The etiology of Leigh syndrome in Chinese patients represents a persistent challenge to clinicians. | YANG Yan-ling SUN Fang ZHANG Yao QIAN Ning YUAN Yun WANG Zhao-xia QI Yu XIAO Jiang-xi WANG Xiao-ying QI Zhao-yue ZHANG Yue-hua JIANG Yu-wu BAO Xin-hua QIN Jiong WU Xi-ru | 2006 | Chinese Medical Journal2006，，5： | 17 |
| 4 | Association of a SLC30A8 Genetic Variant with Monotherapy of Repaglinide and Rosiglitazone Effect in Newly Diagnosed Type 2 Diabetes Patients in China显示文摘Objective To investigate a potential relationship between Solute carrier family 30 (zinc transporter) member 8 (SLC30A8) rs13266634 variant and efficacy of rosiglitazone or repaglinide in treating newly diagnosed Chinese type 2 diabetes patients.Methods A total of 209 diabetic patients without any antihyperglycemic history were recruited and treated with repaglinide or rosiglitazone randomly for 48 weeks (104 and 105 patients,respectively).Anthropometric measurements and clinical laboratory tests were carried out before and after the treatment.An non-synonymous variant rs13266634 was genotyped by matrix-assisted laser desorption ionization-time of flight mass spectroscopy.Results Ninety-one patients in repaglinide group and ninety-three patients in rosiglitazone group completed the study.Δ value of homeostasis model assessment of beta cell function (HOMA-B)and Δ value of fasting proinsulin levels were statistically significant between three genotype groups (P=0.0149 and 0.0246,respectively) after rosiglitazone treatment.However,no genotype association was observed in the repaglinide or rosiglitazone group with other parameters.Conclusion The SLC30A8 variant was associated with the efficacy of insulin sensitizer monotherapy on insulin secretion in patients with newly diagnosed type 2 diabetes mellitus in Shanghai,China. | JIANG Feng LI Qing HU Cheng ZHANG Rong WANG Cong Rong YU Wei Hui LU Jing Yi TANG Shan Shan BAO Yu Qian XIANG Kun San JIA Wei Ping | 2012 | Biomedical and Environmental Sciences2012，25，1： | 8 |
| 5 | Dosage effect of multiple genes accounts for multisystem disorder of myotonic dystrophy type 1显示文摘Multisystem manifestations in myotonic dystrophy type 1(DM1)may be due to dosage reduction in multiple genes induced by aberrant expansion of CTG repeats in DMPK,including DMPK,its neighboring genes(SIX5 or DMWD)and downstream MBNLh However,direct evidence is lacking.Here,we develop a new strategy to generate mice carrying multigene heterozygous mutations to mimic dosage reduction in one step by injection of haploid embryonic stem cells with mutant Dmpk,Six5 and Mbnll into oocytes.The triple heterozygous mutant mice exhibit adult-onset DM1 phenotypes.With the additional mutation in Dmwd,the quadruple heterozygous mutant mice recapitulate many major manifestations in congenital DM1.Moreover,muscle stem cells in both models display reduced sternness,providing a unique model for screening small molecules for treatment of DM1.Our results suggest that the complex symptoms of DM1 result from the reduced dosage of multiple genes. | Qi Yin Hongye Wang Na Li Yifu Ding Zhenfei Xie Lifang Jin Yan Li Qiong Wang Xinyi Liu Liuqing Xu Qing Li Yongjian Ma Yanbo Cheng Kai Wang Cuiqing Zhong Qian Yu Wei Tang Wanjin Chen Wenjun Yang Fan Zhang Chen Ding Lan Bao Bin Zhou Ping Hu Jinsong Li | 2020 | Cell Research2020，30，2： | 7 |
| 6 | Novel synthesis of N-doped graphene as an efficient electrocatalyst towards oxygen reduction显示文摘做氮的 graphene (NG ) 被一个新奇、灵巧、可伸缩的自底向上的方法成功地综合。退火的 NG (NG -- 一) 拥有的高特定的表面区域和一块层次多孔的质地,和在在碱、酸的媒介的氧减小反应的展出显著地改进的 electrocatalytic 活动。分子的动态模拟显示了的 Ab initio 那快速的 H 转移和六成员的 N 结构的热力学的稳定性在 600 敮 x 从 pyrrolic 把包含 N 种类的转变提升了到 | Ruguanq Ma Xiaodong Ren Bao Yu Xia Yao Zhou Chi Sun Qian Liu Jianjun Liu Jiacheng Wang | 2016 | Nano Research2016，9，3： | 6 |
| 7 | BIX-01294-enhanced chemosensitivity in nasopharyngeal carcinoma depends on autophagy-induced pyroptosis显示文摘Nasopharyngeal carcinoma(NPC)is a common cancer in southern China and Southeast Asia.Nowadays,radiotherapy is the therapy of choice for NPC patients,and chemotherapy has been found as an alternative treatment for advanced NPC patients.However,finding novel drugs and pharmacologically therapeutic targets for NPC patients is still urgent and beneficial.Our study showed that BIX-01294(BIX)can induce autophagic vacuoles formation and conversion of LC3B-I to LC3B-II in NPC cells in both dose-and time-dependent manners.Notably,the combination of BIX and chemotherapeutic drugs significantly decreased the cell viability and increased the lactate dehydrogenase release.Meanwhile,BIX plus cis-platinum(Cis)treatment induced pyroptosis in NPC cells as featured by cell swelling and bubble blowing from the plasma membrane,the increased frequency of annexin V and propidium iodide(PI)double-positive cells,as well as the cleavage of gasdermin E(GSDME)and caspase-3.Moreover,the deficiency of GSDME completely shifted pyroptosis to apoptosis.Furthermore,the inhibition of autophagy by chloroquine and the knockout of ATG5 gene significantly blocked the BIX-induced autophagy as well as pyroptosis in both in vitro and in vivo studies.Our data demonstrated that BIX-combined chemotherapeutic drugs could induce the Bax/caspase-3/GSDME-mediated pyroptosis through the activation of autophagy to enhance the chemosensitivity in NPC. | Qian Li Min Wang Yan Zhang Liuqian Wang Wei Yu Xiaomin Bao Biyun Zhang Yanghong Xiang Anchun Deng | 2020 | Acta Biochimica et Biophysica Sinica2020，52，10： | 5 |
| 8 | A global empirical model for estimating zenith tropospheric delay显示文摘Tropospheric delay acts as a systematic error source in the Global Navigation Satellite Systems(GNSS) positioning. Empirical models UNB3, UNB3 m, UNB4 and EGNOS have been developed for use in Satellite-Based Augmentation Systems(SBAS). Model performance, however, is limited due to the low spatial resolution of the look-up tables for meteorological parameters. A new design has been established in this study for improving performance of the tropospheric delay model by more effectively eliminating the error produced by tropospheric delay. The spatiotemporal characteristics of the Zenith Tropospheric Delay(ZTD) were analyzed with findings that ZTD exhibits different annual variations at different locations and decreases exponentially with height increasing. Spherical harmonics are utilized based on the findings to fit the annual mean and amplitude of the ZTD on a global scale and the exponential function is utilized for height corrections, yielding the ZTrop model. On a global scale, the ZTrop features an average deviation of ?1.0 cm and Root Mean Square(RMS) of 4.7 cm compared with the International GNSS Service(IGS) ZTD products, an average deviation of 0.0 cm and RMS of 4.5 cm compared with the Global Geodetic Observing System(GGOS) ZTD data, and an average deviation of ?1.3 cm and RMS of 5.2 cm compared with the ZTD data from the Constellation Observing System of Meteorology, Ionosphere, and Climate(COSMIC). The RMS of the ZTrop model is 14.5% smaller than that of UNB3, 6.0% smaller than that of UNB3 m, 16% smaller than that of UNB4, 14.5% smaller than that of EGNOS and equivalent to the sophisticated GPT2+Saas model in comparison with the IGS ZTD products. The ZTrop, UNB3 m and GPT2+Saas models are finally evaluated in GPS-based Precise Point Positioning(PPP), as the models act to aid in obtaining PPP position error less than 1.5 cm in north and east components and relative large error(>5 cm) in up component with respect to the random walk approach. | YAO Yi Bin ZHANG Bao XU Chao Qian HE Chang Yong YU Chen YAN Feng | 2016 | Science China Earth Sciences2016，59，1： | 4 |
| 9 | A New Type of Polymer-Supported Metallocene Catalyst for Ethylene Polymerization显示文摘A new polymer-supported metallocene catalyst has been prepared. The polymer- supported metallocene displayed considerably high activity in ethylene polymerization, the highest being 3.62(107gPE/molZr(h, the molecular weight of the polyethylene produced was Mn = 1.29(105, about 3-4 times those of corresponding homogeneous zirconocenes. The polymer- supported metallocene keeps the characteristics of homogeneous metallocene catalysts, and offers some features,such as adaptable to gas phase and slurry processes; easy to prepare in low cost; relatively high activity and lower MAO/Zr ratio; lower inorganic residues in the polyolefins as compared to cases of SiO2, Al2O3 or MgCl2; unitary active structure, no complex surface as with SiO2; good control of morphology of the resulting polymer. | Guang Qian YU*, De Ze ZHANG, Fu SHUN, Li Jun QIAO,Tao TANG, Bao Tong HUANG State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences Polymer Chemistry Laboratory, Chemistry Academy of S | 2001 | Chinese Chemical Letters2001，12，3： | 4 |
| 10 | Arsenic trioxide downregulates the expression of annexin II in bone marrow cells from patients with acute myelogenous leukemia显示文摘 | ZHANG Xiao-hui HU Yu BAO Li JIANG Qian YANG Ling-hua LU Xi-jing HONG Mei XIA Ling-hui GUO Tao SHEN Guan-xin ZHU Hong-hu ZHAO Ting SONG Shan-jun | 2009 | Chinese Medical Journal2009，，17： | 3 |
| 11 | Effect of pulsatile perfusion during cardiopulmonary bypass in terms of radial artery sphygmogram显示文摘OBJECTIVE: To investigate a quantitative method for using radial artery pulse waveforms to assess the effect of pulsatile flow during cardiopulmonary bypass(CPB).METHODS: A total of 34 adults with heart disease who underwent open-heart surgery between April2010 and January 2011 were randomized into a pulsatile perfusion group(n=17) and a non-pulsatile perfusion group(n=17). Radial arterial pulse waveforms of pulsatile and non-pulsatile perfusion patients were observed and compared before and during CPB.RESULTS: No pulse waveform could be detected at patients' radial artery in both groups when the aorta was cross-clamped. Pulse waveforms could be detected at pulsatile perfusion patients' radial artery, but could not be detected at non-pulsatile perfusion patients' radial artery during CPB. Additionally, patients' pulse waveforms during pulsatile perfusion were lower than those before the operation.CONCLUSION: Our findings indicate that radial artery sphygmogram can be used as a valid indicator to evaluate the effectiveness of pulsatile perfusion during CPB. | Zhifeng Zhang Jiatuo Xu Enyuan Zhu Qi Zhang Lu Yu Yongbing Qiu Jianguo Tang Zhaofu Fei Xin Li Liping Tu Chouping Han Ying Liu Zhen Guo Changle Zhou Meiyu Shi Yingxin Qian Yimin Bao Xinming Ji | 2014 | Journal of Traditional Chinese Medicine2014，34，6： | 2 |
| 12 | Ultrastructural observation of liver tissue ablation induced by high-intensity focused ultrasound显示文摘UltrastructuralobservationoflivertissueablationinducedbyhighintensityfocusedultrasoundCHENGShuQun1,ZHOUXinDa1,TANGZhaoYo... | CHENG Shu Qun 1, ZHOU Xin Da 1, TANG Zhao You 1, YU Yao 1, BAO Su Su 2 and QIAN De Chu 2 | 1997 | World Journal of Gastroenterology1997，3，3： | 2 |
| 13 | Detection of infectious dengue virus by selective real-time quantitative polymerase chain reaction显示文摘Dear Editor,The dengue virus(DENV)is a single-stranded positivesense RNA virus that belongs to the family Flaviviridae(Gubler,2002),and has four serotypes,DENV1–DENV4,which are transmitted via Aedes aegypti and Aedes albopictus(Rodriguez-Roche and Gould,2013).It has been reported that more than 50 million dengue infections occur each year(Guzman et al.,2010),and a serious outbreak occurred in the Southern Provinces | Xin Huang Xuan Zhou Xiaoyan He Pei Wang Shuai Yue Lixin Wu Yu Zhang Qian Xie Bao Zhang Wei Zhao | 2016 | Virologica Sinica2016，31，4： | 2 |
| 14 | Influence of the biological carbon pump effect on the sources and deposition of organic matter in Fuxian Lake, a deep oligotrophic lake in southwest China显示文摘Biological carbon pumping(BCP)is a key process in which dissolved inorganic carbon in terrestrial aquatic ecosystems is utilized by aquatic autotrophs for photosynthesis and transformed into autochthonous organic matter(AOC).However,the mechanisms underlying BCP and the amount of generated AOC deposited effectively,are still poorly understood.Therefore,we conducted a systematic study combining modern hydrochemical monitoring and a sediment trap experiment in Fuxian Lake(Yunnan,SW China),the second-deepest plateau,oligotrophic freshwater lake in China.Temperature,pH,EC(electrical conductivity),DO(dissolved O2),[HCO3^-],[Ca^2+],SIc,partial CO2(pCO2)pressure,and carbon isotopic compositions of HCO3^-(δ^13CDIc)in water from Fuxian Lake all displayed distinct seasonal and vertical variations.This was especially apparent in an inverse correlation between pCO2 and DO,indicating that variations of hydrochemistry in the lake water were mainly controlled by the metabolism of the aquatic phototrophs.Furthermore,the lowest C/N ratios and highestδ^13Corg were recorded in the trap sediments.Analyses of the C/N ratio demonstrated that the proportions of AOC ranged from 30%to 100%of all OC,indicating that AOC was an important contributor to sedimentary organic matter(OC).It was calculated that the AOC flux in Fuxian Lake was 20.43 t C km^-2 in 2017.Therefore,AOC produced by carbonate weathering and aquatic photosynthesis could potentially be a significant carbon sink and may have an important contribution to solving the lack of carbon sinks in the global carbon cycle. | Haibo He Zaihua Liu Chongying Chen Yu Wei Qian Bao Hailong Sun Yundi Hu Hao Yan | 2019 | Acta Geochimica2019，38，5： | 2 |
| 15 | Taking the pulse of COVID-19:a spatiotemporal perspective显示文摘The sudden outbreak of the Coronavirus disease(COVID-19)swept across the world in early 2020,triggering the lockdowns of several billion people across many countries,including China,Spain,India,the U.K.,Italy,France,Germany,Brazil,Russia,and the U.S.The transmission of the virus accelerated rapidly with the most confirmed cases in the U.S.,India,Russia,and Brazil.In response to this national and global emergency,the NSF Spatiotemporal Innovation Center brought together a taskforce of international researchers and assembled implementation strategies to rapidly respond to this crisis,for supporting research,saving lives,and protecting the health of global citizens.This perspective paper presents our collective view on the global health emergency and our effort in collecting,analyzing,and sharing relevant data on global policy and government responses,human mobility,environmental impact,socioeconomical impact;in developing research capabilities and mitigation measures with global scientists,promoting collaborative research on outbreak dynamics,and reflecting on the dynamic responses from human societies. | Chaowei Yang Dexuan Sha Qian Liu Yun Li Hai Lan Weihe Wendy Guan Tao Hu Zhenlong Li Zhiran Zhang John Hoot Thompson Zifu Wang David Wong Shiyang Ruan Manzhu Yu Douglas Richardson Luyao Zhang Ruizhi Hou You Zhoua Cheng Zhong Yifei Tian Fayez Beaini Kyla Carte Colin Flynn Wei Liu Dieter Pfoser Shuming Bao Mei Li Haoyuan Zhang Chunbo Liu Jie Jiang Shihong Du Liang Zhao Mingyue Lu Lin Li Huan Zhou Andrew Ding | 2020 | International Journal of Digital Earth2020，13，10： | 2 |
| 16 | The development from hyperuricemia to gout:key mechanisms and natural products for treatment显示文摘Gout is a common of inflammatory arthritis and is caused by the deposition of monosodium urate(MSU)crystals as a result of hyperuricemia(HUA).Although HUA is considered to be the main risk factor for gout,only approximately 10%of the individuals with HUA will eventually experience a gout attack.In this review,we first briefly introduce the development of gout and then summarize several possible reasons for its development.Genetic factors play a more prominent role in gout than in other diseases;functional mutations related to urate control and innate immunity components have been found to be associated with gout.Here,we list some of the most prominent genes involved in the pathogenesis of gout.In joints with MSU deposition,mature macrophages may uptake MSU crystals without causing inflammation,and this helps to maintain joints in an asymptomatic state.As an auxiliary inflammation pathway,the ATP-P2X7R-NLRP3 axis may contribute to the amplification of MSU-induced inflammation to affect the development of gout.Finally,this review summarizes the research progress on natural products that can be used in the treatment of HUA and gout. | Lin Liu Dan Wang Mengyang Liu Haiyang Yu Qian Chen Yuzheng Wu Ruixia Bao Yi Zhang Tao Wang | 2022 | Acupuncture and Herbal Medicine2022，2，1： | 2 |
| 17 | Relationship between Waist Circumference and Elevation of Carotid Intima-media Thickness in Newly-diagnosed Diabetic Patients显示文摘Objective Waist circumference, as a brief indicator of visceral obesity, is associated with multi-metabolic disorders and cardiovascular diseases. The present study was aimed to find out the relationship between waist circumference and carotid intima media thickness(C-IMT), as well as the best waist circumference cutoff for identifying C-IMT elevation in Chinese male patients with newly-diagnosed diabetes. Methods Five hundred and seventy-eight patients from Department of Endocrinology and Metabolism in Shanghai Sixth People's Hospital affiliated to Shanghai Jiao Tong University were enrolled. Both physical examination(for measurement of waist circumference) and carotid ultrasonography(for measurement of C-IMT) were performed. Results After grouping according to the quartiles of C-IMT, the waist circumference increased across all its quartiles. The waist circumference in 3rd and 4th quartiles(90.7±9.8 cm and 90.8±9.6 cm) was significant higher than in 1st and 2nd quartiles(P<0.05). When subjects were divided into 4 groups according to waist circumference, the C-IMT of subjects with waist circumference 90-95 cm was significant higher than that of subjects with waist circumference 85-90 cm and less than 85 cm respectively(P<0.05). Both spearman and partial correlation analysis showed that C-IMT was positively correlated with waist circumference(P<0.01). C-IMT was found significantly elevated with the increase of waist circumference. Multiple stepwise regression analysis showed that waist circumference was one of the independent risk factors of C-IMT. After an average of 2.23±0.85 years follow up, there was a significant elevation of C-IMT in the group with baseline waist circumference over 90 cm P<0.05), while no significant difference was detected in the group with baseline waist circumference less than 90 cm(P=0.27). Logistic regression showed that baseline waist circumference over 90 cm was associated with a relative risk to C-IMT elevation of 1.132(95% CI 1.043-1.431, P<0.05). Conclusion Among newly-diagnosed diabetic male patients, waist circumference over 90 cm not only reflects sub-clinical atherosclerosis in early stage, but also predicts the progression of atherosclerosis. | ZHANG Lei SHEN Yun ZHOU Jian PAN Jie Min YU Hao Yong CHEN Hai Bing LI Qing LI Ming BAO Yu Qian JIA Wei Ping | 2014 | Biomedical and Environmental Sciences2014，27，5： | 2 |
| 18 | Improved Cd determination in glasses by laser ablation inductively coupled plasma mass spectrometry using nitrogen as a matrix modifier显示文摘5 – 的增加;到在激光脱离的血浆的中央隧道的 10 mL min −1氮诱导地联合了血浆集体 Spectrometry ( LA-ICP-MS )由一个数量级由 3 的一个因素和减少氧化物干扰增加 Cd 的敏感,它在玻璃样品允许 Cd 的踪迹层次的直接分析。这个简单方法在样品的各种各样的类型为 Cd 的直接决心显示出一个大潜力。 | Qian Ni Zhao Chu Hu Zheng Yu Bao Ya Feng Zhang | 2009 | Chinese Chemical Letters2009，20，1： | 1 |
| 19 | Chemical compounds and pharmacological effects of Rabdosia excisa显示文摘Many kinds of diterpenoids have been isolated from Rabdosia spp.Some of them have anti-microbial effects,counteract inflammation,and inhibit tumor progression activities.We conducted the present study in order to look for bioactive compounds in the medicinal plant Rabdosia excisa.In this study,five compounds were isolated from R.excisa;they were oridonin,isokamebakaurin,oleano-lic acid,ursolic acid,and b-sitosterol.In order to identify the function of the extracts,the activity of antibiotics,anti-oxidation,and immunity test were carried out against these functions.Prospective results were observed in all of the tested items. | PANG Jinsong YU Qian LIU Bao | 2007 | Frontiers in Biology2007，2，1： | 1 |
| 20 | Association of C3 Gene Polymorphisms with Neovascular Age-Related Macular Degeneration in a Chinese Population显示文摘 | Xue-Ting Pei Xiao-Xin Li Yong-Zhen Bao Wen-Zhen Yu Zheng Yan Hui-Jun Qi Tong Qian Hong-Xiang Xiao | 2009 | Current Eye Research2009，，8： | 1 |
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