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| 1 | CeO_2 as the Oxygen Carrier for Partial Oxidation of Methane to Synthesis Gas in Molten Salts: Thermodynamic Analysis and Experimental Investigation显示文摘一种新技术 ? 一到用在熔融的盐媒介的格子氧的合成气的甲烷的直接部分氧化被介绍了。把 CeO2 用作载氧体,热力学数据在显示的反应过程,和结果被计算到用铈氧化物的格子氧的合成气的甲烷的那直接部分氧化在理论是可行的。在一个不锈钢反应堆,温度的效果和 | 的变化数量 ?-Al2O3 在 CH4 变换, H2 和公司选择上支持了 CeO2,分别地被调查。结果显示出那 10%CeO2/|?-Al2O3 在 865 的温度举办最大的反应活动 ??6 号元素碳的化学符号并且上面,在被生产了的气体的 H2/CO 比率到达 2 并且 CH4 变换, H2 和公司选择到达了下列百分比:即 61% , 89% ,和 91% 在 870 点 ??6 号元素碳的化学符号分别地。另外,反应温度的增加为甲烷的部分氧化是有利的。给词调音:部分氧化;甲烷;铈氧化物;合成气; | Yonggang Wei Hua Wang Fang He Xianquan Ao Chiyuan Zhang | 2007 | Journal of Natural Gas Chemistry2007，16，1： | 14 |
| 2 | Human umbilical cord blood stem cell transplantation for the treatment of chronic spinal cord injury Electrophysiological changes and long-term efficacy显示文摘Stem cell transplantation can promote functional restoration following acute spinal cord injury (injury time < 3 months), but the safety and long-term efficacy of this treatment need further exploration. In this study, 25 patients with traumatic spinal cord injury (injury time > 6 months) were treated with human umbilical cord blood stem cells via intravenous and intrathecal injection. The follow-up period was 12 months after transplantation. Results found that autonomic nerve functions were restored and the latent period of somatosensory evoked potentials was reduced. There were no severe adverse reactions in patients following stem cell transplantation. These experimental findings suggest that the transplantation of human umbilical cord blood stem cells is a safe and effective treatment for patients with traumatic spinal cord injury. | Liqing Yao Chuan He Ying Zhao Jirong Wang Mei Tang Jun Li Ying Wu Lijuan Ao Xiang Hu | 2013 | Neural Regeneration Research2013，8，5： | 14 |
| 3 | Endoscopic decompression of the optic canal for traumatic optic neuropathy显示文摘 | Zhen-Hua He Zheng-Bo Lan Ao Xiong Guo-Kuo Hou Ya-Wen Pan Qiang Li Xin-Ding Zhang | 2016 | Chinese Journal of Traumatology2016，19，6： | 8 |
| 4 | A review:Synthesis,modification and photocatalytic applications of ZnIn_(2)S_(4)显示文摘Solar energy is an ideal energy source for solving energy shortages and serious environmental problems.In the past few decades,photocatalytic technology which uses solar energy to deal with the above problems has caused great interest.ZnIn_(2)S_(4),as a layered ternary metal chalcogenide compound,has a series of advantages such as the wide light absorption range and adjustable bandgap.It has been applied in the different fields of photocatalysis in recent years.This review introduced the crystal structures and growth mechanism of ZnIn_(2)S_(4)and summarized the preparation methods of ZnIn_(2)S_(4).Also,the promoted strategies of ZnIn_(2)S_(4)based photocatalytic system and their applications in the pollutant removal,hydrogen evolution,reduction of CO_(2),nitrogen fixation,and chemical synthesis was summarized.Furthermore,the challenges and development directions of the current ZnIn_(2)S_(4)based photocatalytic system were proposed.It is hoped that this review will help researchers design a better ZnIn_(2)S_(4)based photocatalytic system. | Jie Wang Sijia Sun Run Zhou Yangzi Li Zetian He Hao Ding Daimei Chen Weihua Ao | 2021 | Journal of Materials Science & Technology2021，，19： | 6 |
| 5 | Pathological changes in the lungs and lymphatic organs of 12 COVID-19 autopsy cases显示文摘Systematic autopsy and comprehensive pathological analyses of COVID-19 decedents should provide insights into the disease characteristics and facilitate the development of novel therapeutics.In this study,we report the autopsy findings from the lungs and lymphatic organs of 12 COVID-19 decedents—findings that evaluated histopathological changes;immune cell signature and inflammatory factor expression in the lungs,spleen and lymph nodes.Here we show that the major pulmonary alterations included diffuse alveolar damage,interstitial fibrosis and exudative inflammation featured with extensive serous and fibrin exudates,macrophage infiltration and abundant production of inflammatory factors(IL-6,IP-10,TNFo?and IL-I f).The spleen and hilar lymph nodes contained lesions with tissue structure disruption and immune cell dysregulation,including lymphopenia and macrophage accumulation.These findings provide pathological evidence that links injuries of the lungs and lymphatic organs with the fatal systematic respiratory and immune malfunction in critically ill COVID-19 patients. | Qian Liu Yu Shi Jun Cai Yaqi Duan Rongshuai Wang Hongyan Zhang Qiurong Ruan Jiansha Li Lei Zhao Yifang Ping Rong Chen Liang Ren Xiaochun Fei Heng Zhang Rui Tang Xi Wang Tao Luo Xindong Liu Xuequan Huang Zhenhua Liu Qilin Ao Yong Ren Jing Xiong Zhicheng He Haibo Wu Wenjuan Fu Pengnan Zhao Xinwei Chen Guoqiang Qu Yunyun Wang Xi Wang Jia Liu Dongfang Xiang Sanpeng Xu Xiaowei Zhou Qingrui Li Jinghong Ma Heng Li Jie Zhang Sizhe Huang Xiaohong Yao Yiwu Zhou Chaofu Wang Dingyu Zhang Guoping Wang Liang Liu Xiu-Wu Bian | 2020 | National Science Review2020，7，12： | 6 |
| 6 | Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia显示文摘好攻击的 NK 房间白血病(ANKL ) 是在从亚洲的人之中是更流行的 NK 房间瘤的一种稀罕形式并且中央并且南美洲。病人们通常在天以内死到月,甚至在收到迅速的治疗学的管理以后。这里,我们由集成整个染色体执行了 ANKL 的第一全面研究, transcriptome 并且定序指向,象功能的试金一样的 cytokine 数组。在 JAK-STAT 小径的变化在 48% 被识别(14/29 ) ANKL 病人,当细胞外的 STAT3 激发器 IL10 被 56 褶层的一般水准提高时(P < 0.0001 ) 在检查的所有病人的血浆。另外的经常变异的基因包括的 TP53 (34%) , TET2 (28%) , CREBBP (21%) 和 MLL2 (21%) 。耐心的 NK 白血病房间在多重新陈代谢的小径显示出 STAT3 phosphorylation, MYC 表示和 transcriptional 活动的突出的激活。机能上地, STAT3 激活和 MYC 表示为 ANKL 房间的增长和幸存是批评的。发信号的 STAT 调整了发信号的 MYC 抄写节目,和两 STAT, MYC 抄写被要求维持核苷酸合成和 glycolysis 的激活。一起, JAK-STAT 小径在 ANKL 为 genomic 改变和 IL10 刺激代表一个主要目标。这最新发现的 JAK/STAT-MYC-biosynthesis 轴可以在对待白血病的这种子类型为新奇治疗学的策略的发展提供机会。 | Liang Huang Dan Liu Na Wang Shaoping Ling Yuting Tang Jun Wu Lingtong Hao Hui Luo Xuelian Hu Lingshuang Sheng Lijun Zhu Di Wang Yi Luo Zhen Shang Min Xiao Xia Mao Kuangguo Zhou Lihua Cao Lili Dong Xinchang Zheng Pinpin Sui Jianlin He Shanlan Mo Jin Yan Qilin Ao Lugui Qiu Hongsheng Zhou Qifa Liu Hongyu Zhang Jianyong Li Jie Jin Li Fu Weili Zhao Jieping Chen Xin Du Guoliang Qing Hudan Liu Xin Liu Gang Huang Ding Ma Jianfeng Zhou Qian-fei Wang | 2018 | Cell Research2018，28，2： | 5 |
| 7 | Decentration and tilt of plate-haptic multifocal intraocular lenses in myopic eyes显示文摘Background:To investigate the decentration and tilt of plate-haptic multifocal intraocular lenses(MfIOLs)in myopic eyes.Methods:Myopic(axial length[AXL]>24.5 mm)and non-myopic(21.0 mm | Jiaqi Meng Wenwen He Xianfang Rong Ao Miao Yi Lu Xiangjia Zhu | 2020 | Eye and Vision2020，7，1： | 5 |
| 8 | The Relationship between Intrahepatic Distribution of Hepatitis B Virus Core Antigen and Serum ALT, HBV DNA Levels and HBeAg Status显示文摘Objective The clinical significance of differential distribution of hepatitis B virus(HBV)nucleocapsid antigen in hepatocytes remains unknown.The goal of this study is to determine the relationship between distinct HBV core antigen distribution pattern and alanine transaminase(ALT),liver histological inflammatory activity grades,serum HBeAg status and HBV DNA level.Methods Total of 958 cases with chronic hepatitis B were recruited into this study.Liver function tests,serum HBV DNA level,serological HBV markers and liver immunohistochemistry were examined according to the conventional instructions.Chi Square tests were performed to analyze the differences among these groups.Results It was found that 552(58%)cases were tested positive for HBV core antigen by immunohistochemical staining.Cytoplasmic hepatitis B core antigen(HBcAg)expression correlated with ALT level and serum HBV DNA and liver inflammatory activity scores,however,nuclear HBcAg expression in hepatocytes was associated with normal ALT level,lower liver inflammatory activity score and higher serum HBV DNA level and rate of HBeAg positivity.Both nuclear and cytoplasmic HBcAg expression in hepatocytes associated with a middle ALT level and liver inflammatory activity score,higher rate of serum detectable HBeAg and a higher HBV DNA level.However,undetectable core antigen was related to a lower ALT level and histological inflammatory activity grade,lower positive HBeAg rate and HBV DNA level.Conclusions Undetectable liver HBcAg is associated with HBV clearance,ALT normalization and hepatitis B e antigen(HBeAg)seroconversion,and cytoplasmic HBcAg expression associated with higher hepatic inflammatory activity.However,nuclear HBcAg expression correlates with immune tolerance characterized with normal ALT and lower liver inflammatory activity,higher HBV replication level and higher rate of HBeAg positivity. | Qing He Qi-yuan Tang Xiao-hua Le De-liang Lv Xiang-mei Zhang Fei-jian Ao Yi-min Tang Shan Huang John Nunnari Gui-lin Yang | 2012 | 国际感染病学(电子版)2012，1，2： | 4 |
| 9 | Genetic architecture and key genes controlling the diversity of oil composition in rice grains显示文摘Rice grain oil is a valuable nutrient source.However,the genetic basis of oil biosynthesis in rice grains remains unclear.In this study,we performed a genome-wide association study on oil composition and oil concentration in a diverse panel of 533 cultivated rice accessions.High variation for 11 oil-related traits was observed,and the oil composition of rice grains showed differentiation among the subpopulations.We identified 46 loci that are significantly associated with grain oil concentration or composition,16 of which were detected in three recombinant inbred line populations.Twenty-six candidate genes encoding enzymes involved in oil metabolism were identified from these 46 loci,four of which(PAL6,LIN6,MYR2,and ARA6)were found to contribute to natural variation in oil composition and to show differentiation among the subpopulations.Interestingly,population genetic analyses revealed that specific haplotypes of PAL6 and LIN6 have been selected in japonica rice.Based on these results,we propose a possible oil biosynthetic pathway in rice grains.Collectively,our results provide new insights into the genetic basis of oil biosynthesis in rice grains and can facilitate marker-based breeding of rice varieties with enhanced oil and grain quality. | Hao Zhou Duo Xia Pingbo Li Yiting Ao Xiaodong Xu Shanshan Wan Yanhua Li Bian Wu Huan Shi Kaiyue Wang Guanjun Gao Qinglu Zhang Gongwei Wang Jinghua Xiao Xianghua Li Sibin Yu Xingming Lian Yuqing He | 2021 | Molecular Plant2021，14，3： | 4 |
| 10 | Flight dynamics characteristics of canard rotor/wing aircraft in helicopter flight mode显示文摘The aerodynamic layout of the Canard Rotor/Wing(CRW) aircraft in helicopter flight mode differs significantly from that of conventional helicopters. In order to study the flight dynamics characteristics of CRW aircraft in helicopter mode, first, the aerodynamic model of the main rotor system is established based on the blade element theory and wind tunnel test results. The aerodynamic forces and moments of the canard wing, horizontal tail, vertical tail and fuselage are obtained via theoretical analysis and empirical formula. The flight dynamics model of the CRW aircraft in helicopter mode is developed and validated by flight test data. Next, a method of model trimming using an optimization algorithm is proposed. The flight dynamics characteristics of the CRW are investigated by the method of linearized small perturbations via Simulink. The trim results are consistent with the conventional helicopter characteristics, and the results show that with increasing forward flight speed, the canard wing and horizontal tail can provide considerable lift,which reflects the unique characteristics of the CRW aircraft. Finally, mode analysis is implemented for the linearized CRW in helicopter mode. The results demonstrate that the stability of majority modes increases with increasing flight speed. However, one mode that diverges monotonously,and the reason is that the CRW helicopter mode has a large vertical tail compared to the conventional helicopter. The results of the dynamic analysis provide optimization guidance and reference for the overall design of the CRW aircraft in helicopter mode, and the model developed can be used for control system design. | Honggang GAO Ao HE Zhenghong GAO Yang NA Yangping DENG | 2019 | Chinese Journal of Aeronautics2019，32，7： | 3 |
| 11 | Cholesterylation of Smoothened is a calcium-accelerated autoreaction involving an intramolecular ester intermediate显示文摘Hedgehog(Hh)is a morphogen that binds to its receptor Patched 1 and activates Smoothened(SMO),thereby governing embryonic development and postnatal tissue homeostasis.Cholesterol can bind and covalently conjugate to the luminal cysteine-rich domain(CRD)of human SMO at the D95 residue(D99 in mouse).The reaction mechanism and biological function of SMO cholesterylation have not been elucidated.Here,we show that the SMO-CRD undergoes auto cholesterylation which is boosted by calcium and involves an intramolecular ester intermediate.In cells,Hh stimulation elevates local calcium concentration in the SMO-localized endosomes through store-operated calcium entry.In addition,we identify the signaling-incompetent SMO D95E mutation,and the D95E mutant SMO can bind cholesterol but cannot be modifed or activated by cholesterol.The homozygous Smo^(O99E/D99E) knockin mice are embryonic lethal with severe developmental delay,demonstrating that cholesterylation of CRD is required for full-length SMO activation.Our work reveals the unique autocatalytic mechanism of SMO cholesterylation and an unprecedented role of calcium in Hh signaling. | Ao Hu Jing-Zan Zhang Jie Wang Chen-Chen Li Meng Yuan Gang Deng Zi-Cun Lin Zhi-Ping Qiu Hu-Yue Liu Xian-Wei Wang Peng-Cheng Wei Xiao He Xiaolu Zhao Wen-Wei Qiu Bao-Liang Song | 2022 | Cell Research2022，32，3： | 3 |
| 12 | A New Steel Teeming Technology by Using Electromagnetic Induction Heating System in Ladle显示文摘In order to overcome the pollution of the tratitional nozzle sand into the molten steel in tundish,a new method is proposed in this paper.In this method,the nozzle sand is substituted with iron-carbon alloy particles which have the same or similar compositions as the liquid steel.During casting processes,iron-carbon alloy forms solidification shell and the sintered layer in the upper nozzle to block the molten steel.When the slide gate is opened,the eletromagnetic induction heating is used to melt them so as to achieve 100%smoothly steel teeming.The electromagnetic induction heating effects were analyzed theoretically in the new slide gate system.Then the new method has been experimentally tested by using self-designed experimental device.The results show that the electromagnetic induction heating can complete the steel teeming within the required time.Furthermore,this steel-teeming technology can further improve the cleanliness of liquid steel. | LI De-jun WANG Qiang LIU Xing-an Gao Ao WANG Xue-bin DONG Jie KATSUKIYO Marukawa HE Ji-cheng | 2012 | Journal of Iron and Steel Research(International)2012，19，S2： | 3 |
| 13 | Derivation of Haploid Neurons from Mouse Androgenetic Haploid Embryonic Stem Cells显示文摘Dear Editor,Haploid embryonic stem cells(ha ESCs)hold great potential for genetic screening and the analysis of recessive phenotypes.Several studies have recently reported the generation of mammalian ha ESCs through gamete manipulation,and evaluated the benefits of using them for studying functional genomics in different mammals[1–4].These ha ESCs have been shown to give rise to three | He Xu Chunmei Yue Ting Zhang Yuanyuan Li Ao Guo Jiaoyang Liao Gang Pei Jinsong Li Naihe Jing | 2017 | Neuroscience Bulletin2017，33，3： | 3 |
| 14 | Environment surveillance of filamentous fungi in two tertiary care hospitals in China显示文摘背景侵略真菌的感染在 immunocompromised 病人组成了病态和死亡的一个日益重要的原因。在这研究,一个监视工程在 China.Methods 以二所大第三级的医院的三个不同特别护理单位被进行一个一个年监视工程在分别地在北中国和西南中国定位了的二所第三级的医院里被进行。空气,表面和自来水一个月在一个中央特别护理单位被取样两次,骨头髓移植联合起来,一个神经外科特别护理单位并且一现场移植部门。环境条件象湿度,发生的温度和事件那样,例如,礼品也在 sampling.Results 的时候来宾,保健职员和清洗全体乘务员被记录真菌的负担是的空气西南中国医院和北中国医院里的 91.94 cfu/m3 和 71.02 cfu/m3 分别地。从空气和表面收集的五很流行的真菌是毛丛 spp, Cladospcrium spp, Altemaria spp,曲霉属菌 spp。并且 Saccharomyces spp。在西南中国医院里,同时毛丛 spp,镰刀霉 spp,曲霉属菌 spp, Altemaria spp。并且 Cladospcrium spp。在北中国医院里。最少的污染部门是特别护理单位,并且最重的污染部门是神经外科特别护理联合起来。百分之 73 所有表面在北中国医院里检验了,百分之 86 在西南中国医院里产出真菌。来自北中国医院的百分之 54 件水样品和百分之 49 从西南中国医院产出 fungi.Conclusions 这些调查结果建议真菌包括空气在医院的环境存在,出现并且流水。空气和表面真菌的负担在一年波动。空气真菌的负担在夏天和秋天在冬季并且更高是更低的,但是很少超过了可接受的水平。更高的价值在北中国医院和 5 月里在 5 月期间被创造到 8 月到 6 月和 9 月到 10 月在西南中国医院里。在空气之间的关联真菌的负担和湿度,以及人员被观察。 | HAO Zhen-feng AO Jun-hong HAO Fei YANG Rong-ya ZHU He ZHANG Jie | 2011 | Chinese Medical Journal2011，，13： | 3 |
| 15 | An Outbreak of SARS in a Diabetes Room of a General Hospital without Infected Medical Staff显示文摘Objective To investigate the epidemiologic features of an outbreak of SARS that occurred in a single diabetes room of a general hospital in Beijing in late March 2003.Methods Field investigation was carried out in the ward,the nursing log and the hospitalization medical record of correlative patients were consulted.SARS-CoV in serum specimen from SARS patient was detected by PCR.Results The room where SARS outbreak occurred was on the 13th floor of the 16-story main ward building.There were 6 beds in the room,living with 6 female patients(aged 45-67)who were all hospitalized due to type2 diabetes.On March 24,2003,Patient 1 began to have a fever and cough,chest X-ray showed pneumonia.Five and six days later,Patient 2 and Patient 3 began to have a fever,respectively.Finally,all of these 3 patients died.Their beds were all at the same side of the room,and the other 3 patients at the opposite side were not infected.Serum SARS CoV-RNA of the Patient 3 was positive by nest-PCR.The daughter-in-law of Patient 1who accompanied Patient 1 by the bedside several days,mainly near the window,upwind of Patient 1,was not infected.Medical staff,family members and visitors of the 6 patients were not infected.Conclusions This outbreak was not transmitted by aerosol.The distance droplets travels could be up to 3.43 meters.Droplet spread has direction,and the droplets direction of propagation is closely related with the wind direction and speed.Those at the downwind position of SARS patients were susceptible to be infected.Medical staff wore face masks and good natural ventilation of this ward building may be important reasons for the prevention of infection. | Chun-ling Liu Jun Cheng He Gao Bo Zhang Qun Yuan Ao Tong Yi-an Liang Hong Tang Xiao-hong Guan | 2013 | 国际感染病学(电子版)2013，2，4： | 3 |
| 16 | Maternal intake restriction programs the energy metabolism, clock circadian regulator and m TOR signals in the skeletal muscles of goat offspring probably via the protein kinase A-cAMP-responsive element-binding proteins pathway显示文摘The biological mechanism by which maternal undernutrition increases the metabolic disorder risk of skeletal muscles in offspring is not fully understood.We hypothesize that maternal intake restriction influences metabolic signals in the skeletal muscles of offspring via a glucagon-mediated pathway.Twentyfour pregnant goats were assigned to the control group(100%of the nutrients requirement,n=12)and restricted group(60%of the control feed allowance from pregnant days 45 to 100,n=12).Blood and Longissimus thoracis muscle were sampled from dams(100 d of gestation),fetuses(100 d of gestation),and kids(90 d after birth)in each group.The data were analyzed using the linear MIXED model,with the multiple comparison method of SIDAK applied.Intake restriction reduced(P<0.05)the total blood protein of dams and fetuses.Maternal restriction decreased(P<0.05)the cAMP-responsive element-binding protein 1(CREB1),CREB-binding protein(CREBBP),protein kinase A(PKA),aryl hydrocarbon receptor nuclear translocator-like protein 1(BMAL1),protein kinase B(AKT1),mammalian target of rapamycin(mTOR),and regulatory-associated protein of mTOR(RPTOR)mRNA expression in the fetuses,and reduced(P<0.05)the CREBBP,nuclear receptor subfamily 1 group H member 3(NR1 H3),D-box binding PAR bZIP transcription factor(DBP)and PKA mRNA levels in the kids,but increased(P<0.05)the peroxisome proliferator-activated receptor gamma coactivator 1 alpha(PGC1 A)and tuberous sclerosis 2(TSC2)mRNA levels in the fetuses.The mRNA expression of clock circadian regulator(CLOCK)and TSC2 genes was increased(P<0.05)in the restricted kids.The protein expression of total PKA and phosphorylated PKA in the restricted fetuses and kids were downregulated(P<0.05),and the protein expression of total mTOR and phosphorylated mTOR were reduced(P<0.05)in the restricted fetuses and kids.Maternal intake restriction regulated fat oxidation,protein synthesis,and circadian clock expression in the muscles of the offspring probably via the glucagon-mediated PKA-CREB pathway,which reveals a noteworthy molecular pathway that maternal undernutrition leads to metabolic adaptation of skeletal muscle in offspring. | Xiaoling Zhou Qiongxian Yan Hong Yang Ao Ren Zhixiong He Zhiliang Tan | 2021 | Animal Nutrition2021，，4： | 2 |
| 17 | Combining 53BP1 with BRCA1 as a biomarker to predict the sensitivity of poly(ADP-ribose) polymerase (PARP) inhibitors显示文摘别对治疗在有 BRCA1 缺乏的癌症的病人的一半上作出回应与 poly (自动数据处理核糖) 聚合酶(PARP ) 禁止者。在这研究,我们报导 53BP1 和 BRCA1 的联合可以用作 PARP 禁止者敏感的 biomarker。基于四个相应再结合修理(HR ) 的 mRNA 层次基因和 PARP 禁止者敏感,我们选择了 BRCA1 缺乏的 MDA-MB-436 房间进行 RNA 干扰。减少 53BP1,然而并非另外的三 HR 基因的表示,被发现降低 simmiparib 敏感。另外,我们产生了 53BP1 //BRCA1/ 由抄写的同种细胞的变体像使活跃之物的受动器核酸酶(TALEN ) 技术并且发现那弄空的 53BP1 随他们的 IC 50 价值的 36.7 褶层增加损害了 PARP 禁止者敏感。与它 PARP 禁止者敏感上的效果一致, 53BP1 损失减轻了房间周期拘捕和 apoptosis 并且部分恢复了 HR 功能。重要地, 53BP1 弄空戏剧性地减少了 PARP 禁止者的能力在 vivo 压制肿瘤生长。simmiparib 的抑制率为 BRCA1 缺乏的 MDA-MB-436 异种皮移植是 74.16% ,但是仅仅 7.79% 为 53BP1/BRCA1-deficient 异种皮移植。在双缺乏的房间的重新表示的 53BP1 恢复了 PARP 禁止者敏感和 HR 管理者的层次。认为至少 10%BRCA1 缺乏的胸和卵巢的癌症减少了 53BP1 的表示,用有象为耐心的选择的 biomarker 的 BRCA1 的 53BP1 的联合应该减少与 PARP 禁止者经历无益的治疗的病人的数字。 | Zhong-min YANG Xue-mei LIAO Yi CHEN Yan-yan SHEN Xin-ying YANG Yi SU Yi-ming SUN Ying-lei GAO Jian DING Ao ZHANG Jin-xue HE Ze-hong MIAO | 2017 | Acta Pharmacologica Sinica2017，38，7： | 2 |
| 18 | A time domain correction method for Doppler-distortion signal from acoustic moving source显示文摘Doppler effect widely exists in the signal from the moving acoustic source.In order to solve such problems as frequency shift and frequency band expansion,a time domain correction method is presented in this paper.First,the discrete time vector for interpolation and the amplitude restoration formula is derived based on the moving relationship and the Morse acoustic theory,then the amplitude weights are corrected and the distortion signal is interpolated.Every point of the discrete signal is operated separately in time domain.Compared with the existing frequency domain methods,this method does not need to know the characteristic frequency beforehand and would not be influenced by the blending of the frequency band.Hence,this method can be employed to correct multiple frequency signals and it is also a simple and effective Doppler effect reduction method. | LIU Fang HE Qingbo SHEN Changqing HU Fei ZHANG Ao KONG Fanrang | 2014 | Chinese Journal of Acoustics2014，33，1： | 2 |
| 19 | Current research progress of photopolymerized hydrogels in tissue engineering显示文摘Owing to the special fo rmation of photopolymerized hydrogels,they can effectively control the formation of hydrogels in space and time.Moreover,the photopolymerized hydrogels have mild formation conditions and biocompatibility;therefore,they can be widely used in tissue engineering.With the development and application of manufacturing technology,photopolymerized hydrogels can be widely used in cell encapsulation,scaffold materials,and other tissue engineering fields through more elaborate manufacturing methods.This review covers the types of photoinitiators,manu facturing technologies for photopolymerized hydrogels as well as the materials used,and a summary of the applications of photopolymerized hydrogels in tissue engineering. | Ao Sun Xinye He Xiao Ji Danrong Hu Meng Pan Linghong Zhang Zhiyong Qian | 2021 | Chinese Chemical Letters2021，32，7： | 2 |
| 20 | A Kinetic Study of Selective Hydrogenation of Carbon Monoxide to C_2 Oxygenates on Rh-Mn-Li-Fe/SiO_2 Catalyst显示文摘The kinetics of CO hydrogenation for the synthesis of C2 oxygenates over Rh-Mn-Li-Fe/SiO2was investigated. Kinetic parameters for the formation of ethanol, acetaldehyde, C2 oxygenates, methanol and methane were obtained. The activation energy, H2 and CO dependence orders for ethanol and acetaldehyde formation differed greatly, the large difference seemed to imply that they were formed through different intermediates. | Hongmei Yin, Yunjie Ding, Hongyuan Luo, Daiping He, Weimiao Chen, Zhiyong Ao, Liwu LinNatural Gas Utilization and Applied Catalysis Laboratory, Dalian Institute of Chemical Physics, The Chinese Academy of Sciences, Dalian 116023, China | 2003 | Journal of Natural Gas Chemistry2003，12，4： | 2 |
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