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| 1 | Hepatic expression and cellular distribution of the glucose transporter family显示文摘Glucose and other carbohydrates are transported into cells using members of a family of integral membrane glucose transporter (GLUT) molecules. To date 14 members of this family, also called the solute carrier 2A proteins have been identified which are divided on the basis of transport characteristics and sequence similarities into several families (Classes 1 to 3). The expression of these different receptor subtypes varies between different species, tissues and cellular subtypes and each has differential sensitivities to stimuli such as insulin. The liver is a contributor to metabolic carbohydrate homeostasis and is a major site for synthesis, storage and redistribution of carbohydrates. Situations in which the balance of glucose homeostasis is upset such as diabetes or the metabolic syndrome can lead metabolic disturbances that drive chronic organ damage and failure, confirming the importance of understanding the molecular regulation of hepatic glucose homeostasis. There is a considerable literature describing the expression and function of receptors that regulate glucose uptake and release by hepatocytes, the most import cells in glucose regulation and glycogen storage. However there is less appreciation of the roles of GLUTs expressed by non parenchymal cell types within the liver, all of which require carbohydrate to function. A better understanding of the detailed cellular distribution of GLUTs in human liver tissue may shed light on mechanisms underlying disease pathogenesis. This review summarises the available literature on hepatocellular expression of GLUTs in health and disease and highlights areas where further investigation is required. | Sumera Karim David H Adams Patricia F Lalor | 2012 | World Journal of Gastroenterology2012，18，46： | 5 |
| 2 | The Stroke Outcomes and Neuroimaging of Intracranial Atherosclerosis (SONIA) Trial显示文摘 | E Feldmann J L. Wilterdink A Kosinski M Lynn M I. Chimowitz J Sarafin H H. Smith F Nichols J Rogg H J. Cloft L Wechsler J Saver S R. Levine C Tegeler R Adams M Sloan | 2007 | Neurology2007，，24： | 2 |
| 3 | Bee Parasitic Mite Syndrome(II):The Role of Varroa Mite and Virues 显示文摘 | Hung A C F Adams J R Shimanuki H | 1995 | American Bee Journal1995，12，： | 2 |
| 4 | Surrogate end points in heart failure 显示文摘 | LEC C R ADAMS K F PATTERSON J H | 2002 | Ann Pharmacother2002，36，3： | 1 |
| 5 | Resection of nonresectable liver metastases from colorectal cancer after neoadjuvant chemotherapy显示文摘 | Adam R Levi F | 1996 | Ann Surg1996，224，4： | 1 |
| 6 | Use of High-pressure Processing for Oyster Shucking and Shelf-life Extension 显示文摘 | lie H Adams R M Farkas D F | 2002 | Journal of Food Science2002，67，2： | 1 |
| 7 | Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial显示文摘 | John R Teerlink Gad Cotter Beth A Davison G Michael Felker Gerasimos Filippatos Barry H Greenberg Piotr Ponikowski Elaine Unemori Adriaan A Voors Kirkwood F Adams Maria I Dorobantu Liliana R Grinfeld Guillaume Jondeau Alon Marmor Josep Masip Peter S Pang | 2013 | The Lancet . 2013 (9860)2013，，9860： | 1 |
| 8 | Use of High-pressure Processing for Oyster Shucking and Shelf- life Extension 显示文摘 | H He R M Adams D F Farkas | 2002 | Journal of food science2002，67，2： | 1 |
| 9 | A network architecture for distributed multimedia system显示文摘 | Houh H H | 1994 | IEEE1994，，： | 1 |
| 10 | Resection of nonresectable livermetastases from colorectal cancer after neoadjuvant chemotherapy显示文摘 | Bismuth H Adam R Levi F | 1996 | Ann Surg1996，224，： | 1 |
| 11 | Comparisons of several transport models in their predictions in typical space radiation environments显示文摘 | Lin Z W Adams J H Barghouty A F | 2012 | Advances in Space Research2012，49，4： | 1 |
| 12 | Resection of nonresectable liver metastases from colorectal cancer after neoadjuvant che- motherapy显示文摘 | Bismuth H Adam R L6vi F | 1996 | Ann Surg1996，224，4： | 1 |
| 13 | Surgieal treatment of the ischemic mitrai valve显示文摘 | ADAMS D H FILSOUFI F AKLOG L | 2002 | J Heart Valve Dis2002，，： | 1 |
| 14 | Resection of nonresectable liver metastases from colorectal cancer after neoadjuvant chemotherapy显示文摘 | Bismuth H Adam R Levi F | 1996 | Ann Surg1996，224，4： | 1 |
| 15 | Risk factors for com- plications after pancreatic head resection 显示文摘 | Adam U Makowiec F Riediger H | 2004 | Am J Surg2004，187，2： | 1 |
| 16 | Mixed Metal Complexes of Some Tetradentate Bifunctional Schiff Bases显示文摘 | Bl-Hatw M T Amrallah A H Adam F A | 1990 | J Indian Chem Soc1990，67，： | 1 |
| 17 | A 20-kilodalton protein is required for efficient production of the Bacillus thuringiensis subsp,israelensis 27-kilodalton crystal protein in Escherichia coli显示文摘 | ADAMS L F JONATHAN E V WHITELY H R | 1989 | J Bacteriol1989，171，： | 1 |
| 18 | Characterization and evolution of ovine MHC class Ⅱ DQB sequence polymorphism 显示文摘 | Van Oorschot R A H Maddox J F Adams L J | 1994 | Animal genetics1994，25，6： | 1 |
| 19 | Environmental gradients,plant distribution,and species richness in arctic salt marsh near Prudhce Bay,Alaska显示文摘 | DALE W F LYNN E N ADAM H F | 2004 | Wetlands Ecology and Management2004，12，： | 1 |
| 20 | Resection of nonresectable liver metastases from colorectal cancer after neoadjurant chemotherapy显示文摘 | Bismuth H Adam R Levi F | 1996 | Ann Surg1996，224，4： | 1 |
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