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| 1 | Predictive factors for anastomotic leakage after laparoscopic colorectal surgery显示文摘Every colorectal surgeon during his or her career is faced with anastomotic leakage(AL); one of the most dreaded complications following any type of gastrointestinal anastomosis due to increased risk of morbidity, mortality, overall impact on functional and oncologic outcome and drainage on hospital resources. In order to understand and give an overview of the AL risk factors in laparoscopic colorectal surgery, we carried out a careful review of the existing literature on this topic and found several different definitions of AL which leads us to believe that the lack of a consensual, standard definition can partly explain the considerable variations in reported rates of AL in clinical studies. Colorectal leak rates have been found to vary depending on the anatomic location of the anastomosis with reported incidence rates ranging from 0 to 20%, while the laparoscopic approach to colorectal resections has not yet been associated with a significant reduction in AL incidence. As well, numerous risk factors, though identified, lack unanimous recognition amongst researchers. For example, the majority of papers describe the risk factors for left-sided anastomosis, the principal risk being male sex and lower anastomosis, while little data exists defining AL risk factors in a right colectomy. Also, gut microbioma is gaining an emerging role as potential risk factor for leakage. | Antonio Sciuto Giovanni Merola Giovanni D De Palma Maurizio Sodo Felice Pirozzi Umberto M Bracale Umberto Bracale | 2018 | World Journal of Gastroenterology2018，24，21： | 48 |
| 2 | Abeta oligo- mers induce neuronal oxidative stress through an N-methyl-D-aspar- tate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine 显示文摘 | DE FELICE F G VELASCO P T LAMBERT M P | 2007 | J Biol Chem2007，282，11： | 1 |
| 3 | Alzheimer's disease- type neuronal tau hyperphosphorylation induced by A beta oli- gomers 显示文摘 | De Felice F G Wu D l ambert M P | 2008 | Neurobiol Aging2008，29，9： | 1 |
| 4 | The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain显示文摘 | Lazzaro D Price M de Felice M | 1991 | Development1991，113，： | 1 |
| 5 | Thyroid development and its disorders:genetics and molecular mechanisms显示文摘 | DE FELICE M DI LAURO R | 2004 | Endocr Rev2004，25，： | 1 |
| 6 | Engagement ofdescending inhibition from the rostral ventromedial medulla protects against chronic neuropathic pain显示文摘 | De Felice M Sanoja R Wang R.Z Vera-Portocarrero L Oyarzo J King T | | 0，，： | 1 |
| 7 | Triptan-induced latent sensitization: A possible basis for medication overuse headache显示文摘 | De Felice M Ossipov MH Wang R | 2010 | Ann Nenrol2010，67，3： | 1 |
| 8 | Thyroid nuclear factor 1 (TTF-1)contains a homeodomain and displays a novel DNA binding specificity显示文摘 | Guazzi S Price M De Felice M | 1990 | EMBO J R1990，，9： | 1 |
| 9 | A New Version of the Price's Algorithm for Global Optimization显示文摘 | Brachetti P De Felice C M Dipillo G | 1997 | Journal of global optimization (S0925-5001)1997，10，： | 1 |
| 10 | Germline-specific ex- pression of the Oct-4/green fluorescent protein (GFP) transgene in mice 显示文摘 | Yoshimizu T Sugiyama N De Felice M | 1999 | Dev Growth Differ1999，41，： | 1 |
| 11 | Physical and functional interaction between the minichromosome maintenance - like DNA helicase and the single - stranded DNA binding protein from the erenarchaeen Sulfolobus solfatarieus 显示文摘 | Carpentieri F De - Felice M De - Falco M | 2002 | J Biol Chem2002，277，12： | 1 |
| 12 | A mouse model for hereditary thyroid dysgenesis and cleft palate显示文摘 | de FELICE M OVITT C BIFFALI E | 1998 | Nat Genet1998，19，： | 1 |
| 13 | Thyroid nuclear factor 1(TTF-1)contains a homeodomain and displays a novel DNA binding specificity显示文摘 | Guazzi S Price M De Felice M | 1990 | EMBO J1990，9，11： | 1 |
| 14 | Thyroid development and its disorders : Genetics and molecular mechanisms 显示文摘 | de Felice M di Lauro R | 2004 | Endocr Rev2004，25，5： | 1 |
| 15 | Thyroid development and its disorders: genetics and molecular mechanisms显示文摘 | De Felice M Di Lauro R | 2004 | Endocr Rev2004，25，5： | 1 |
| 16 | Serum inhibin A, inhibin B, and pro-αC levels are altered after surgically or pharmacologically induced menopause显示文摘 | Luigi Cobellis Stefano Luisi Ilaria Pezzani Fernando M Reis Vincenzo De Leo Felice Petraglia | 2002 | Fertility and Sterility2002，，4： | 1 |
| 17 | Update on medication-overuse headache 显示文摘 | De Felice M Ossipev MH Porreca F | 2011 | Curr Pain Headache Rep2011，15，1： | 1 |
| 18 | Cosmology of generalized modified gravity models 显示文摘 | CARROLL S M DE FELICE A DUVVURI V | 2005 | Phys Rev D2005，71，06： | 1 |
| 19 | Soluble protein oli-gomers as emerging toxins in Alzheimers and other amyloid disea-ses显示文摘 | Ferreira S T Vieira M N De Felice F G | 2007 | IUBMB Life2007，59，45： | 1 |
| 20 | A mouse model for hereditary thyroid dysgenesis and cleft palate 显示文摘 | De Felice M OVitt C Biffali E | 1998 | Nat Genet1998，19，4： | 1 |
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