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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | Experimental behavior of a steel structure under natural fire 显示文摘 | Wald F Sim?es da Silva L Moore D B | 2006 | Fire Safety Journal2006，41，7： | 1 |
| 3 | Slurry sampling for the determination of mercury in rice using cold vapor atomic absorption spectrometry显示文摘 | Silva L O B da Silva D G Leao D J | 2012 | Food Analytical Methods2012，5，6： | 1 |
| 4 | Parametric Study of Adhesive Joints with Composites 显示文摘 | NETO J A B P CAMPILHO R D S G DA SILVA L F M | 2012 | International Journal of Adhesion and Adhesives2012，，： | 1 |
| 5 | Analytical models of adhesively bonded joints-Part I:literature survey显示文摘 | da Silva L F M das Neves P J C Adams R D | 2009 | International Journal of Adhesion and Adhesives2009，29，3： | 1 |
| 6 | Comprehensive two-dimensional gas chromatography/mass spectrometric analysis of pepper voatiles显示文摘 | Cardeal Z L Gomes da Silva M D Marriott P J | 2006 | Rapid Commun Mass Spectrom2006，20，： | 1 |
| 7 | Inhibitory action of aqueous coffee ground extracts on the corrosion of carbon steel in HC1 solution 显示文摘 | TORRESS V V AMADO R S de sAC F FERNANDEZ T L da SILVA RIEHI C A TORRES A G D'ELIA E | 2011 | Corrosion Science2011，53，： | 1 |
| 8 | Experimental behavior of a steel structure under natural fire显示文摘 | Wald F Sim?es da Silva L Moore D B | 2006 | Fire Safety Journal2006，41，7： | 1 |
| 9 | The endocannabinoid system in renal cells: regulation of Na+ transport by CB1 receptors through distinct cell signaling pathways显示文摘 | Sampaio L S Taveira Da Silva R Lima D | 2015 | Br J Pharmacol2015，172，19： | 1 |
| 10 | Small strain viscoelastic behaviour of wheat gluten-pentosan mixtures 显示文摘 | Santos D M J Monteiro S R Da Silva J A L | 2005 | Eur Food Res Technol2005，，221： | 1 |
| 11 | Storage temperature effect on histamine formation in big eye tuna and skipjack显示文摘 | SILVA C C G da PONTE D J B DAPKEVICIUS M L N | 1998 | Journal of Food Science1998，63，4： | 1 |
| 12 | Parameterized fast deeoupled power flow methods for obtaining the maximum loading point of power systems Part Ⅰ and Part Ⅱ显示文摘 | Alves D A Da Silva L C P Castro C A | 2004 | Electric Power Systems Research2004，69，： | 1 |
| 13 | Adhesively bonded joints in composite materials:an overview显示文摘 | Banea M D Da Silva L F M | | 0，，： | 1 |
| 14 | Genome-wide comparative diversity uncovers multiple targets of selection for improvement in hexaploid wheat landraces and cultivars 显示文摘 | Cavanagh CS Chao S Wang BE Huang BE Stephen S Kiani S Forrest K Saintenac C Brown-Guedira GL Akhunova A See D Bai G Pumphrey M Tomar L Wong D Kong S Reynolds M da Silva ML Bockelman H Talbert L Anderson JA Dreisigacker S Baenziger S Carter A Korzun V Morrell PL Dubcovsky J Morell MK Sorrells ME Hayden MJ Akhunov E | 2013 | PNAS2013，110，： | 1 |
| 15 | Meta-datasnapshotting : A simple mechanism for file systemconsistency显示文摘 | Soares L Krieger 0 Da Silva D | 2003 | SNAPI2003，3，： | 1 |
| 16 | Low tem- perature properties of winterized methyl babassu biodiesel 显示文摘 | Silva M C D da Silva L M Brandgo K S | 2013 | J Therm Anal Calorim2013，115，1： | 1 |
| 17 | Integration in new product development : Case study in a large Brazilian high-technolo- gy company 显示文摘 | Jugend D da Silva S L | 2012 | Journal of Technology Management & Innovation2012，7，1： | 1 |
| 18 | Identification of pumpkin populations as resistance sources against the Zucchini yellow virus (ZYMV)显示文摘 | Moura M da C C L Zerbini E M da Silva D J H de Queiroz M A | 2005 | Horticultura Brasileira2005，23，： | 1 |
| 19 | A short review of their antimicrobial activities显示文摘 | Da Silva C M Da Silva D L Modolo L V | | 0，，01： | 1 |
| 20 | Study of ethylic Babassu biodiesel properties at low temperatures显示文摘 | Silva M C D Da Silva L M Santos N A | 2011 | J Therm Anal Calorim2011，106，2： | 1 |
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