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| 1 | Suppression of Jasmonic Acid-Mediated Defense by Viral-Inducible MicroRNA319 Facilitates Virus Infection in Rice显示文摘MicroRNAs (miRNAs ) 是植物开发和主人病毒相互作用的枢轴的调节的人。然而,角色和涉及病毒的感染和主人危险性的特定的 miRNAs 的行动模式仍然保持大部分不清楚。在这研究,我们给那瑞斯看引起 miR319 的增加的累积,但是减少的破旧绝技病毒(RRSV ) 感染调整 miR319 的 TCP (TEOSINTE BRANCHED/CYCLOIDEA/PCF ) 的表示基因,特别 TCP21,在米饭植物。转基因的米饭植物 overexpressing miR319 或 downregulating TCP21 展出了像疾病的显型并且与野类型的植物比较显示出显著地更高的危险性到 RRSV。相反,仅仅温和的疾病症状在感染 RRSV 的线 overexpressing TCP21 并且特别在转基因的植物 overexpressing 被观察 miR319 抵抗的 TCP21。miR319 的 RRSV 感染和 overexpression 在米饭与 JA 生合成和信号相关的基因的 downregulated 表示一起引起了减少的内长的 jasmonic 酸(JA ) 层次。然而,有甲基 jasmonate 的米饭植物的治疗减轻了 RRSV 引起并且减少了病毒累积的疾病症状。一起拿,我们的结果建议由在米饭的 RRSV 感染的 miR319 的正式就职压制调停 JA 的防卫便于病毒感染和症状开发。 | Chao Zhang Zuomei Ding Kangcheng Wu Liang Yang Yang Li Zhen Yang Shan Shi Xiaojuan Liu Shanshan Zhao Zhirui Yang Yu Wang Luping Zheng Juan Wei Zhenguo Du Aihong Zhang Hongqin Miao Yi Li Zujian Wu Jianguo Wu | 2016 | Molecular Plant2016，9，9： | 27 |
| 2 | Introgression of qPE9-1 allele,conferring the panicle erectness,leads to the decrease of grain yield per plant in japonica rice(Oryza sativa L.)显示文摘圆锥花序建筑学是仔细与产量有关形成。qPE9-1 基因被证明了广泛地在产量很高的米饭栽培变种开发被过去常,授与在装饰用的梨树米饭的直立的圆锥花序特性。最近, qPE9-1 成功地被克隆;然而,谷物产量上的基因效果还每直立的圆锥花序等位基因 qPE9-1 的植物是争论的。在现在的学习,低垂的圆锥花序父母 Nongken 57,带 qpe9-1 等位基因,被用作周期性父母到连续地回交到从双 haploid (DH ) 的一根典型直立的圆锥花序线人口(Wuyunjing 8/Nongken 57 ) ,它以前被显示带 qPE9-1 等位基因。因此,一双 near-isogenic 线(无) 被开发。在无之间的农学的特点的比较证明当 qpe9-1 被 qPE9-1 代替时,圆锥花序建筑学从低垂树立被改变;而且,圆锥花序长度,植物高度, 1000 谷物重量和 tillers 显著地被减少,因而在 30% 每植物导致谷物产量的戏剧的减少。因此,我们断定 qPE9-1 是控制圆锥花序建筑学的一个主要因素,并且 qPE9-1 有多种的自然,与每植物的谷物产量上的否定效果。这结果强烈建议直立的圆锥花序等位基因 qPE9-1 应该在产量很高的繁殖实践和另外的有利基因被使用。另外,吃并且煮质量上的 qPE9-1 的效果也在现在的学习被讨论。 | Xiuhua Yi Zujian Zhang Shengyuan Zeng Chunyan Tian Juncheng Peng Min Li Yue Lu Qingcai Meng Minghong Gu Changjie Yan | 2011 | Journal of Genetics and Genomics2011，38，5： | 20 |
| 3 | Tolerance to low phosphorus in rice varieties is conferred by regulation of root growth显示文摘Phosphorus use efficiency(PUE)can be improved through cultivation techniques and breeding.However,little is known about rice(Oryza sativa L.)agronomic and physiological traits associated with high PUE.We characterized the agronomic and physiological traits of rice varieties with different tolerances to low phosphorus in nutrient solution.Two varieties with strong tolerance to low phosphorus(STVs)and two with weak tolerance(WTVs)were grown at normal(NP,control)and low phosphorus(LP,1/20 of NP)concentrations.Plants grown at LP produced significantly lower grain yield than those grown at NP.WTVs yields were lower than STVs yields.Compared to NP,LP significantly increased phosphorus translocation efficiency(PTE),internal phosphorus efficiency(IPE)and phosphorus harvest index(PHI).Under the LP condition,PTE and IPE were higher for STVs than for WTVs.LP also reduced tiller number,shoot biomass,leaf area index(LAI),leaf photosynthetic rate,and mean root diameter of both kinds of varieties at the main growth stages,but to a lower extent in STVs.LP significantly increased the number of productive tillers,root biomass,root-shoot ratio,root bleeding rate,and root acid phosphatase(RAP)activity.Total root length,root oxidation activity(ROA),and root total and active absorbing surface areas for STVs were significantly increased under LP,whereas the opposite responses were observed for WTVs.Total root length,ROA,root bleeding rate,root active absorbing surface area,and RAP activity were positively and significantly correlated with grain yield,PTE,and IPE.These results suggest that the tolerance of rice varieties to a low-phosphorus growth condition is closely associated with root growth with higher biomass and activity. | Yaping Deng Chuanbao Men Shengfeng Qiao Wenjie Wang Junfei Gu Lijun Liu Zujian Zhang Hao Zhang Zhiqin Wang Jianchang Yang | 2020 | The Crop Journal2020，8，4： | 8 |
| 4 | Identification of Pns12 as the second silencing suppressor of Rice gall dwarf virus显示文摘RNA silencing is a conserved mechanism found ubiquitously in eukaryotic organisms.It has been used to regulate gene expression and development.In addition,RNA silencing serves as an important mechanism in plants' defense against invasive nucleic acids,such as viruses,transposons,and transgenes.As a counter-defense,most plants,and some animal viruses,encode RNA silencing suppressors to interfere at one or several points of the silencing pathway.In this study,we showed that Pns12 of RGDV (Rice gall dwarf virus) exhibits silencing suppressor activity on the reporter green fluorescent protein in transgenic Nicotiana benthamiana line 16c.Pns12 of RGDV suppressed local silencing induced by sense RNA but had no effect on that induced by dsRNA.Expression of Pns12 also enhanced Potato virus X pathogenicity in N.benthamiana.Collectively,these results suggested that RGDV Pns12 functions as a virus suppressor of RNA silencing,which might target an upstream step of dsRNA formation in the RNA silencing pathway.Furthermore,we showed that Pns12 is localized mainly in the nucleus of N.benthamiana leaf cells. | WU JianGuo WANG ChunZheng DU ZhengGuo CAI LiJun HU MeiQun WU ZuJian LI Yi XIE LianHui | 2011 | Science China(Life Sciences)2011，54，3： | 7 |
| 5 | The effects of orientation control via tension-compression on microstructural evolution and mechanical behavior of AZ31 Mg alloy sheet显示文摘The grain orientation control via twinning activity on deformation features is of great significance to offer a key insight into understanding the deformation mechanism of Mg alloy sheets.The{10–12}twinning were performed by pre-strain paths,i.e.,tension(6%)and compression(5%)perpendicular to the c-axis along extrusion direction(ED),to investigate the microstructural evolution and mechanical properties of AZ31 Mg alloy sheets.The distinction in the texture evolution and strain hardening behavior was illustrated in connection with the pre-strain paths for the activities of twinning and slip.The result shows that the activation of the deformation mode was closely bound up with the grain orientation and the additional applied load direction.The{10–12}twin-texture components with c-axis//ED were generated by precompression,which can provide an appropriate alternative to accommodate the thin sheet thickness strain and enhance the room temperature formability of Mg alloy sheet. | Qingshan Yang Bin Jiang Bo Song Zujian Yu Dewei He Yanfu Chai Jianyue Zhang Fusheng Pan | 2022 | Journal of Magnesium and Alloys2022，10，2： | 4 |
| 6 | Study on the Coincident-Loop Transient Electromagnetic Method in Seafloor Exploration——Taking Jiaodong Polymetallic Mine as a Model显示文摘The transient electromagnetic(TEM)method becomes more urgent than ever for marine ex-ploration due to abundant resource reserves and the increasing undersea engineering construction activities,especially in the offshore exploration of mineral deposits such as Sanshandao gold mine.However,the re-search and application of TEM method in marine environment are still challenged by many problems.Such contradiction motivates our study on the coincident-loop TEM in seafloor exploration.The TEM response of coincident loops is firstly derived in the integral form,based on the potential functions in Helmholtz equ-ations for a magnetic source locating in the whole-space layered model.The frequency-domain vertical magnetic field is described as the Hankel integral with double first-order Bessel functions of first kind.Se-condly,the time-domain induced voltage is obtained by transforming the frequency-domain response through the cosine transform and then taking the derivative of time.To simultaneously solve the Hankel transform and the cosine transform,a novel algorithm is introduced by adapting the fixed-point quadra-ture and extrapolation via the Shanks transformation.Finally,a typical conductivity model for marine po-lymetallic deposit is designed to investigate the characteristic of TEM response under various conditions.Numerical results demonstrate that existence of conductive seawater causes the TEM response to increase significantly and decay slower.The air-sea reflected electromagnetic waves lead to a significantly large fake negative response(NR)in shallower seawater with depth less than 300 m.Increase in the height of loops will weaken and delay the anomaly response and shorten the observation time-window.The height of configu-ration should be no more than 100 m for shallower targets and 50 m for deeper targets,respectively.The observation time-window should cover 10-1000 ms.Increase in the radius of loops only enhances the TEM response proportionally but hardly improves the relative anomaly.The vertical resolution on the low-resistivity target approximates 20 m for the configuration considered in the study.Decreases in D.C.resistivity and chargeability cause the positive response(PR)to increase significantly and decay more ra-pidly.Meanwhile,the NR is advanced and enlarged significantly and decays slower compared with the PR.The influence of time constant is not monotony and there exists an optimal value for producing the maxi-mum NR.As the frequency parameter increases,the PR is caused to decay more rapidly without magni-tude change and the NR is advanced and decays more rapidly with significant increase in magnitude.The influence of frequency parameter is more pronounced than that of time constant. | Yixing Ma Junhua Hu Yanjun Chang Zujian Liu | 2021 | Journal of Earth Science2021，32，1： | 3 |
| 7 | Cleavage of the Babuvirus Movement Protein B4 into Functional Peptides Capable of Host Factor Conjugation is Required for Virulence显示文摘Banana bunchy top virus(BBTV)poses a serious danger to banana crops worldwide.BBTV-encoded protein B4 is a determinant of pathogenicity.However,the relevant molecular mechanisms underlying its effects remain unknown.In this study,we found that a functional peptide could be liberated from protein B4,likely via proteolytic processing.Site-directed mutagenesis indicated that the functional processing of protein B4 is required for its pathogenic effects,including dwarfism and sterility,in plants.The released protein fragment targets host proteins,such as the large subunit of RuBisCO(RbcL)and elongation factor 2(EF2),involved in protein synthesis.Therefore,the peptide released from B4(also a precursor)may act as a non-canonical modifier to influence host-pathogen interactions involving BBTV and plants. | Jun Zhuang Wenwu Lin Christopher J.Coates Pengxiang Shang Taiyun Wei Zujian Wu Lianhui Xie | 2019 | Virologica Sinica2019，34，3： | 1 |
| 8 | Lead toxicity, uptake, and translocation in different rice cultivars显示文摘 | Jianguo Liu Kunquan Li Jiakuan Xu Zujian Zhang Tanbin Ma Xiaolong Lu Jianchang Yang Qingsen Zhu | 2003 | Plant Science2003，，4： | 1 |
| 9 | Speciation analysis of lead in marine animals by using capillary electrophoresis couple online with inductively coupled plasma mass spectrometry显示文摘 | Yiquan Chen Limei Huang Weihua Wu Yajuan Ruan Zujian Wu Zhimin Xue FengFu Fu | 2014 | ELECTROPHORESIS2014，，9： | 1 |
| 10 | Steadystate simulation of screw liquid chillers 显示文摘 | Fu Long Ding Guoliang Su Zujian | 2002 | Applied Thermal Engineering2002，22，15： | 1 |
| 11 | Ribozyme-mediated resistance to rice dwarf virus and the transgene silencing in the progeny of transgenic rice plants显示文摘 | Shengcheng Han Zujian Wu Huaiyi Yang Rong Wang Yin Yie Lianhui Xie Po Tien | 2000 | Transgenic Research2000，，3： | 1 |
| 12 | Polycomb group protein EZH2‐mediated E‐cadherin repression promotes metastasis of oral tongue squamous cell carcinoma显示文摘 | Cheng Wang Xiqiang Liu Zujian Chen Hongzhang Huang Yi Jin Antonia Kolokythas Anxun Wang Yang Dai David T.W. Wong Xiaofeng Zhou | 2011 | Mol Carcinog2011，，3： | 1 |
| 13 | Research on key in uence factors of laser overlap welding of automobilebody galvanized steel 显示文摘 | Genyu Chen Lifang Mei Minun Zhang Yi Zhang Zujian Wang | 2013 | Optics & Laser Technology2013，，45： | 1 |
| 14 | Polarization of tumor-associated macrophages by TLR7/8 conjugated radiosensitive peptide hydrogel for overcoming tumor radioresistance显示文摘Radioresistance reduces the antitumor efficiency of radiotherapy and further restricts its clinical application,which is mainly caused by the aggravation of immunosuppressive tumor microenvironment(ITM).Especially tumor-associated macrophages(TAMs)usually display the tumor-promoting M2 phenotype during high-dose fractional radiotherapy mediating radiotherapy resistance.Herein,the toll like receptor agonist TLR7/8a was conjugated with radiosensitive peptide hydrogel(Smac-TLR7/8 hydrogel)to regulate TAMs repolarization from M2 type into M1 type,thus modulating the ITM and overcoming the radioresistance.The Smac-TLR7/8 hydrogel was fabricated through self-assembly with nanofibrous morphology,porous structure and excellent biocompatibility.Uponγ-ray radiation,Smac-TLR7/8 hydrogel effectively polarized the macrophages into M1 type.Notably,combined with radiotherapy,TAMs repolarization regulated by Smac-TLR7/8 hydrogel could increase tumor necrosis factor secretion,activate antitumor immune response and effectively inhibit tumor growth.Moreover,TAMs repolarization rebuilt the ITM and elicited the immunogenic phenotypes in solid tumors,thus enhanced the PD1-blockade efficacy through increasing tumor infiltrating lymphocytes(TILs)and decreasing Treg cells in two different immune activity tumor mice models.Overall,this study substantiated that recruiting and repolarization of TAMs were critical in eliciting antitumor immune response and overcoming radioresistance,thus improving the efficacy of radiotherapy and immunotherapy. | Yumin Zhang Zujian Feng Jinjian Liu Hui Li Qi Su Jiamin Zhang Pingsheng Huang Weiwei Wang Jianfeng Liu | 2022 | Bioactive Materials2022，7，10： | 1 |
| 15 | Steady-state simulation of screw liquid chillers 显示文摘 | FU Long DING Guoliang SU Zujian | 2002 | Applied Thermal Engineering2002，22，15： | 1 |
| 16 | Elimination of upper bracket resonance in extremely high head Francis hydro-generators显示文摘 | Yongyao Luo Zhengwei Wang Guodong Chen Zujian Lin | 2008 | Engineering Failure Analysis2008，，1： | 1 |
| 17 | Steady-state simulation of screw liquid chillers显示文摘 | Fu Long Ding Guoliang Su Zujian | 2002 | Applied Thermal Engineering2002，22，： | 1 |
| 18 | Steadystate simulation of screw liquid chillers 显示文摘 | Fu Long Ding Guoliang Su Zujian | 2002 | Applied Thermal Engineering2002，22，15： | 1 |
| 19 | Steadystate simulation of screw liquid chillers显示文摘 | Long Fu Guoliang Ding Zujian Su | 2002 | Applied Termal Engineering2002，22，15： | 1 |
| 20 | Titanium alloy composited with dual-cytokine releasing polysaccharide hydrogel to enhance osseointegration via osteogenic and macrophage polarization signaling pathways显示文摘Titanium alloy has been widely used in orthopedic surgeries as bone defect filling.However,the regeneration of high-quality new bones is limited due to the pro-inflammatory microenvironment around implants,resulting in a high occurrence rate of implant loosening or failure in osteological therapy.In this study,extracellular matrix-mimetic polysaccharide hydrogel co-delivering BMP-2 and interleukin(IL)-4 was composited with 3D printed titanium alloy to promote the osseointegration and regulate macrophage response to create a pro-healing microenvironment in bone defect.Notably,it is discovered from the bioinformatics data that IL-4 and BMP-2 could affect each other through multiple signal pathways to achieve a synergistic effect toward osteogenesis.The composite scaffold significantly promoted the osteoblast differentiation and proliferation of human bone marrow mesenchyme stem cells(hBMSCs).The repair of large-scale femur defect in rat indicated that the dual-cytokinedelivered composite scaffold could manipulate a lower inflammatory level in situ by polarizing macrophages to M2 phenotype,resulting in superior efficacy of mature new bone regeneration over the treatment of native titanium alloy or that with an individual cytokine.Collectively,this work highlights the importance of M2-type macrophages-enriched immune-environment in bone healing.The biomimetic hydrogel–metal implant composite is a versatile and advanced scaffold for accelerating in vivo bone regeneration,holding great promise in treating orthopedic diseases. | Yaping Wang Zujian Feng Xiang Liu Chunfang Yang Rui Gao Wenshuai Liu Wenbin Ou-Yang Anjie Dong Chuangnian Zhang Pingsheng Huang Weiwei Wang | 2022 | Regenerative Biomaterials2022，9，1： | 0 |
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