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404篇 您的检索式:作者名="Zimmerman R D"
    题名 作者 年代 出处 被引量
1Relationship between HER-2 overexpression and brain metastasis in esophageal cancer patients显示文摘AIM:To study if HER-2 overexpression by locally advanced esophageal cancers increase the chance of brain metastasis following esophagectomy.METHODS:We retrospectively reviewed the medical records of esophageal cancer patients who underwent esophagectomy at University of Iowa Hospitals and Clinics between 2000 and 2010.Data analyzed consisted of demographic and clinical variables.The brain metastasis tissue was assayed for HER-2 overexpression utilizing the FDA approved DAKO Hercept Test.RESULTS:One hundred and forty two patients were reviewed.Median age was 64 years(36-86 years).Eighty eight patients(62%) received neoadjuvant chemoradiotherapy.Pathological complete and partial responses were achieved in 17(19%) and 71(81%) patients.Cancer relapsed in 43/142(30%) patients.The brain was the first site of relapse in 9/43 patients(21%,95% CI:10%-36%).HER-2 immunohistochemistry testing of the brain metastasis tissue showed that 5/9(56%) cases overexpressed HER-2(3+ staining).CONCLUSION:HER-2 overexpression might be associated with increased risk of brain metastasis in esophageal cancer patients following esophagectomy.Further studies will be required to validate this observation.Taher Abu Hejleh Barry R DeYoung Eric Engelman Jeremy M Deutsch Bridget Zimmerman Thorvardur R Halfdanarson Daniel J Berg Kalpaj R Parekh William R Lynch Mark D Iannettoni Sudershan Bhatia Gerald Clamon 2012World Journal of Gastrointestinal Oncology2012,4,5:5
2Impact of carbadox on rate,efficiency,and composition of growth in pigs with a low or high level of immune system activation显示文摘STAHLY T S WILLIAMS N H ZIMMERMAN D R 1994J Anim Sci1994,72,1:1
3Diagnostic marker coop- erative study for the diagnosis of myocardial infarction显示文摘Zimmerman J Fromm R Meyer D 1999Circu- lation1999,99,13:1
4Mat- power: steady- state operations, planning and analysis tools for power systems research and education 显示文摘Zimmerman R D Murillo - Samchez C E Thomas R J 2011IEEE Transac- tions on Power Systems2011,26,1:1
5Effects of chronic immune system activation on the rate,efficiency,and composition of growth and lysine ceeds of pigs fed from 6 to 7 kg显示文摘WILLIAMS N H STAHLY T S ZIMMERMAN D R 1997J Anim Sci1997,75,:1
6Stability- constrained optimal power flow 显示文摘GAN D THOMAS R J ZIMMERMAN R D 2000IEEE Trans on Power Systems2000,15,2:1
7Is growth of eelgrass nitrogen limited? A numerical simulation of the effects of light and nitrogen on the growth dynam- ics of Zostera marina 显示文摘Zimmerman R C Smith R D Alberte R S 1987Marine Ecology Progress Series1987,,41:1
8Colostral milk fat percentage and pig performance are enhanced by feeding the leucine metabolite β-hydroxy-β-methylbutyrate to sows显示文摘Nissen S L Faidley T D Zimmerman D R 1984J Anim Sci1984,72,9:1
9Autolysis of c- galactosidase of defatted soy flakes: Influence on nutritive value forchickens显示文摘Angel C R Sell J L Zimmerman D R 1988JAgrFoodChem1988,36,:1
10Use of plasma urea nitrogen as a rapid response criterion to determine the lysine requirement of pigs 显示文摘Coma J Carrion D Zimmerman D R 1995Journal of Animal Science1995,73,2:1
11The effect of dietary active dry yeast supplement on performance of sows during gestation-lactation and their pigs显示文摘JURGENS M H RIKABI R A ZIMMERMAN D R 1997Journal of Animal Science1997,75,:1
12Use of plasma urea nitro- gen as a rapid response criterion to determine the lysine re- quirements of pigs显示文摘Coma J Carrion D Zimmerman D R 1995J Sci1995,73,2:1
13High-resolution solutionNMR structure of the Z domain of staphylococcal proteinA 显示文摘Tashiro M Tejero R Zimmerman D E 1997Journal of Molecular Biology1997,272,4:1
14Relationship of rate of lean tissue growth and other factors to concentrat; on of urea in plasma of pigs显示文摘Coma J Zimmerman D R Carrion D 1995J Anim Sci1995,73,12:1
15Dietary conjugated linoleic acid modulates phenotype and effect or functions of porcine CD8+ lymphocytes显示文摘Bassaganya R J Hontecillas M R Zimmerman D R 2001Anim Sci2001,4,:1
16Variation in sexual reproduction in orchids and itsevolutionary consequences: a spasmodic journey to diversification 显示文摘TREMBLAY R L ACKERMAN J D ZIMMERMAN J 2005Biol J Linn Soc2005,84,1:1
17The effect of dietary active dry yeast supplement on performance of sows during gestation lactation and their pigs显示文摘Jurgens M H Rikabi R A Zimmerman D R 1997J Anim Sci1997,75,3:1
18Regulation of TIGR/MYOC gene expression in human trabecular meshwork cells显示文摘Polansky J R Fauss D J Zimmerman C C 2000Eye2000,14,3:1
19Stabilityconstrained optimal power flow显示文摘Gan D Thomas R J Zimmerman R D 2000IEEE Trans on PowerSystems2000,15,2:1
20CNS stem cells express a new class of intermediate filament protein 显示文摘 Zimmerman L B McKay R D G 1990Cell1990,60,:1
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