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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson's disease显示文摘 | Tang B Xiong H Sun P Zhang Y Wang D Hu Z Zhu Z Ma H Pan Q Xia JH Xia K Zhang Z | 2006 | 中国生物学文摘2006，20，8： | 30 |
| 3 | 慢性阻塞性肺疾病加重期间肠道和肺部微生物的动态变化显示文摘肠道-肺微生态系统紊乱和调节障碍在慢性阻塞性肺疾病(COPD)恶化过程中发挥关键性作用然而,COPD急性加重期肠道-肺菌群的动态变化及其在疾病病因学中的潜在作用仍知之甚少。研究者为了解慢性阻塞性肺疾病急性加重期(AECOPD)肠道和肺部微生物的动态变化,在15例AECOPD患者急性发作第1、7天和第4天纵向收集90份标本(痰液和粪便标本各45份)。 | Sun Z Zhu QL Shen Y 曾雪涛(编译) | 2020 | 中华医学杂志2020，100，40： | 23 |
| 4 | A delivery strategy for rotenone microspheres in an animal model of Parkinson's disease.显示文摘 | Huang J Liu H Gu W Yan Z Xu Z Yang Y Zhu X Li Y | 2006 | 中国生物学文摘2006，20，9： | 16 |
| 5 | Effect of metabolic structures and energy requirements on curdlan production by Alcaligenes faecalis显示文摘 | Zheng, ZY Lee, AW Zhan, XB Shi, Z Wang, L Zhu, L Wu, JR Lin, CC | 2007 | 中国生物学文摘2007，21，10： | 13 |
| 6 | PslG, a self-produced glycosyl hydrolase, triggers biofilm disassembly by disrupting exopolysaccharide matrix显示文摘Biofilms 是在细胞外的矩阵嵌入的微生物的联系表面的社区。Exopolysaccharide 是在维持 biofilm 建筑学并且保护居民 biofilm 细菌免受抗菌剂和主人免疫者攻击的伤害的细胞外的矩阵的一个批评部件。然而,指向矩阵 exopolysaccharides 的自我生产的因素,仍然糟糕被理解。这里,我们显示出那 PslG,在 Pseudomonas aeruginosa 涉及关键 biofilm 矩阵 exopolysaccharide Psl 的合成的蛋白质,阻止 biofilm 形成并且拆卸存在在外长地供应的在 nanomolar 集中的分钟以内的 biofilms。PslG 的水晶结构显示 endoglycosidase 的典型特征。PslG 主要破坏 Psl 矩阵从 biofilms 驱散细菌。PslG 处理显著地提高 biofilm 敏感到抗菌素和巨噬细胞房间,导致在一只老鼠的改进 biofilm 清理植入感染模型。而且, PslG 对大量 Pseudomonas 种类显示出 biofilm 抑制和拆卸活动,显示它在与 biofilm 相关的复杂并发症作斗争的大潜力。 | Shan Yu Tiantian Su Huijun Wu Shiheng Liu Di Wang Tianhu Zhao Zengjun Jin Wenbin Du Mei-Jun Zhu Song Lin Chua Liang Yang Deyu Zhu Lichuan Gu Luyan Z Ma | 2015 | Cell Research2015，25，12： | 13 |
| 7 | MRI阴性药物难治性颞叶癫痫合并抑郁症患者的静息态功能磁共振研究显示文摘背景抑郁症在颞叶癫痫中发生率高达50%~60%,而30%的药物难治性颞叶癫痫患者可表现为头颅核磁共振(MRI)无明显异常,这部分患者相较于伴有海马硬化的药物难治性颞叶癫痫患者出现继发性全面强直阵挛发作的机率更高。因此,MRI阴性药物难治性颞叶癫痫合并抑郁症的患者,生活质量更差、自杀风险更高,更需要癫痫外科手术治疗。 | 朱曦 陈蕾 罗程 Zhu X He Z Luo C | 2018 | 癫痫杂志2018，4，3： | 11 |
| 8 | Cloning and expression of NS3 cDNA fragment of HCV genome of Hebei isolate in E.coli显示文摘CloningandexpressionofNS3cDNAfragmentofHCVgenomeofHebeiisolateinE.coliZHUFenLu,LUHaoYing,LIZhuoandQIZhongTianSubjectheadin... | Zhu, FL Lu, HY Li, Z Qi, ZT | 1998 | World Journal of Gastroenterology1998，4，2： | 7 |
| 9 | 血清netrin-1增加与缺血性脑卒中预后改善相关显示文摘先前的实验研究表明,血清netrin-1与缺血性脑卒中进展相关。进一步了解缺血性脑卒中患者中netrin-1的变化可能为缺血性脑卒中的预后评估提供新的思路。该研究旨在探讨血清netrin-1与缺血性脑卒中预后的关系。研究人员测定3346例中国急性缺血性脑卒中抗高血压试验(China antihypertensive trial in acute ischemic stroke,CATIS)中缺血性脑卒中患者基线血清netrin-1水平,所有患者均在脑卒中发病后3个月进行随访。主要观察指标是脑卒中发病后3个月内死亡和严重残疾(改良Rankin 量表评分≥3)。 | 刘莉 叶鹏 Guo D Zhu Z Zhong C Peng H Wang A Xu T Peng Y Xu T Chen CS Li Q Ju Z Geng D Chen J Zhang Y He J | 2019 | 中华高血压杂志2019，27，5： | 6 |
| 10 | Short-term Exposure to Fine Particles and Risk of Cause-Specific Mortality--China,2013-2018显示文摘What is already known about this topic?Short-term exposure to PM2.5 has been associated with population excess death.This issue is of critical concern in China given its high level of exposure to PM2.5 compared to that of the rest of the world.What is added by this report?Existing studies were conducted from 2013-2015 and have failed to capture the full effects of China’s actions towards cleaner air in recent years,such as the first Action Plan for Air Pollution Prevention and Control issued in 2013.This study uses the longest time series data to date from 2013-2018,provides the latest evidence on PM2.5 and cause-specific death nationwide,and identifies regional patterns of PM2.5-related effects as well as PM2.5-related susceptible populations.What are the implications for public health practice?This study suggests that the development of standards and the implementation of actions to clean the air and protect public health should be tailored to PM2.5-related sensitive diseases,susceptible populations,and regional patterns. | Chen Chen Tiantian Li Lijun Wang Jinlei Qi Wangying Shi Mike Z He Qinghua Sun Jiaonan Wang Huanhuan Zhu Xiaoming Shi | 2019 | China CDC weekly2019，1，1： | 5 |
| 11 | Age-related changes in glutathione and glutathione-related enzymes in rat brain.显示文摘 | Zhu Y Carvey PM Ling Z | 2006 | 中国生物学文摘2006，20，9： | 4 |
| 12 | cDNA microarray analysis of differential gene expression in Candida albicans biofilm exposed to farnesolides显示文摘 | Cao YY Cao YB Xu Z Ying K IA Y Xie Y Zhu ZY Chen WS Jiang YY | 2006 | 第二军医大学学报2006，27，4： | 3 |
| 13 | Priming of the Cells: Hypoxic Preconditioning for Stem Cell Therapy显示文摘 | Zheng Z Wei Yan-Bing Zhu James Y Zhang Myles R McCrary Song Wang Yong-Bo Zhang Shan-Ping Yu Ling Wei | 2017 | Chinese Medical Journal2017，，19： | 3 |
| 14 | Microstructural Analysis of Ultrasonic Welded AA6061 by Electron Backscattered Diffraction显示文摘Ultrasonic welding can be used to join plastic and metal through high-frequency (more than 20 kHz) acoustic vibrations. Aluminium alloy is widely used in electronics, automotive and aerospace. The mechanical vibrations used during ultrasonic metal welding are introduced horizontally. During ultrasonic metal welding, a complex process is triggered involving static forces, oscillating shearing forces and a moderate temperature increase in the welding area. As the energy is introduced to the weld zone, there are three important phenomena occurring which are surface effect, volume effect and thermal effect. As it is known, microstructure is directly linked to the mechanical properties including fatigue resistance, fatigue life and fracture strength. So the microstructure analysis is important to evaluate the ultrasonically welded aluminium alloy’s properties. Also, mechanical properties of metal sheets, such as plastic anisotropy and formability, can be improved by a proper crystallographic texture control. That means the texture has great influence on the plastic anisotropy of the final recrystallized sheets. Optical microscopy (OM) can be used for showing the grain size and grain shape. However, to examine the relationship between mechanical behaviour and microstructure of the weldment, optical microscopy(OM) is not sufficient. OM cannot delineate a grain structure in the weld zone. The etched surface exhibited granularity at the micron level, but it was not clear if that reflected the grain structure. Electron backscatter diffraction (EBSD) in an SEM has become the most widely used technique for determination of microtexture. In this research, high-resolution electron backscatter diffraction is used to study the effects of the vibration on the evolution of microstructure in AA6061. The orientation image maps (OIM), polar figures (PF), and orientation distribution functions (ODF) of the samples are obtained. The characteristics of the crystallographic orientation, the grain structure and the grain boundary are analysed to find the effect of ultrasonic vibration on the microstructure and texture of the bond. The ultrasonic vibration will lead to exceptional refinement of grains to a micron level along the bond area and affect the crystallographic orientation. The grain size of upper foil is much smaller than that of the lower foil. And ultrasonic vibration results in a very weak texture with some characteristic intensity of a rotated cube-orientation and the Brass-orientation and S-orientation. In the lower foil, there is no much influence of the ultrasonic vibration. So there is very strong cube orientation in the lower foil. | Zhu Z Wynne B P Ghassemieh E Siddiq A | 2009 | 稀有金属材料与工程2009，38，A03： | 2 |
| 15 | 贝尔麻痹影响大脑默认模式网络的功能连接(英文)显示文摘目的贝尔麻痹是一种常见的特发性面神经病变,导致病变侧的面部肌肉运动功能丧失。作者探讨了贝尔麻痹对大脑默认模式网络(DMN)功能连接的影响。材料与方法使用1.5 T MR成像仪获取静息态f MRI数据,包括健康志愿者35名及不同病理状态下的面瘫患者52例次。使用双重回归独立成分分析方法处理数据。结果发现面瘫不同病理状态下DMN的功能连接发生了不同的变化。在面瘫疾病早期,DMN功能连接在右侧初级感觉皮层、初级运动皮层、背外侧前额叶显著增强;在面瘫后期,DMN功能连接在双侧中扣带回、楔前叶、右侧富内侧前额叶、后扣带回显著增强;在面瘫康复后,DMN功能连接在左侧舌回、小脑显著增强。结论在面瘫不同病理阶段,DMN的功能连接存在着明显的不同,涉及到感觉运动,运动映射,情感以及认知等不同功能脑区。 | Abdalla Z Mohamed Chuanfu Li Jeungchan Lee Seulgi Eun Yifang Zhu Yuanyuan Wu Jun Yang Kyungmo Park | 2014 | 磁共振成像2014，5，6： | 2 |
| 16 | Inhibition of epstein-Barr-virus-transformed human chornic lymphocytic leukaemic B cells with monoclonal antibody-adriamycin ( doxorubicin ) conjugates 显示文摘 | Zhu Z Kralovec J | 1995 | Cancer Immunol Immunother1995，40，4： | 2 |
| 17 | 基于EKF的永磁同步电机定子绕组和转子磁铁温升估计显示文摘选dq坐标下的电机模型,用3阶EKF算法,来估计电机定子绕组的电阻值和转子磁体的磁通量,和静态时20℃室温下测得的定子绕组阻值和转子磁通量作比较,进而计算出对应的电机定子绕组和转子绕组的温度值.电阻值估计和磁通估计分别独立进行,通过对实验电机的实际测量和估计值进行比较具有较好的一致性. | 张忠英 姜晓亮 孙频东 Zhu Z Q | 2011 | 南京师范大学学报(工程技术版)2011，11，1： | 2 |
| 18 | The use of ensemble to identify forecasts with small and large uncertainty显示文摘 | Toth Z Zhu Y J Marchok T | 2001 | Wea Forecasting2001，16，8： | 2 |
| 19 | Renal dysfunction and its relative factors in metabolic syndrome显示文摘 | Jin Y H Zhu Z M Zhao Z G | 2003 | Am J Hypertens2003，16，5： | 2 |
| 20 | Prevention and control of hepatitis B in China显示文摘 | Sun Z Ming L Zhu X | 2002 | J Med Virol2002，67，： | 1 |
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