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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | Leber's hereditary optic neuropathy is associated with the mitochondrial ND4 G11696A mutation in five Chinese families显示文摘 | Zhou XT Wei QP Yang L Tong Y Zhao FX Lu CJ Qian YP Sun YH Lu F Qu J Guan MX | 2006 | 中国生物学文摘2006，20，4： | 18 |
| 3 | The regulation of rotenone-induced inflammatory factor production by ATP-sensitive potassium channel expressed in BV-2 cells显示文摘 | Liu X Wu JY Zhou F Sun XL Yao HH Yang Y Ding JH Hu G | 2006 | 中国生物学文摘2006，20，10： | 11 |
| 4 | Polymorphisms of MTHFD,plasma homocysteine levels, and risk of gastric cancer in ahigh-risk Chinese population显示文摘Purpose:Accumulative evidence suggests that folate has a protective effect on gastric cancer. The methylenetetrahyd-rofolate dlehydrogenase(MTHFD) plays an important role in folate and homocysteine metabolisms, and polymorphisms of MTHFD may result in disturbance of the folate-mediated homocysteine pathway. The aim of this study is to test the hypothesis that genetic variants of MTHFD and plasma homocysteine levels are associated with risk of gastric cancer and modulated by genotypes of methylenetetrahydrofolate reductase(MTHFR). Experimental Design: We genotyped G1958A and T401C in MTHFD and C677T in MTHFR and detected total plasma homocysteine(tHcy) levels in a case-control study of 589 gastric cancer cases and 635 cancer-free controls in a high-risk Chinese population. Results:The variant genotypes of MTHFD 1958AA and 401CC were associated with a significantly increased risk of gastric canceradjusted odds ratio(OR), 2.05; 95% confidence interval(95% CI),1.34-3.13 for 1958AA; adjusted OR,1.43; 95% CI,1.14-1.80 for 401CC compared with 1958GG/GA and 401TT/TC genotypes, respectively. Both of the effects were more evident in the subjects carrying MTHFR 677CT/TT genotypes. The average tHcy level was significantly higher in gastric cancer cases than in controls(P < 0.01), and the upper quartile of tHcy (> 13.6 mu mol/L) was associated with an 82% significantly increased risk of gastric cancer, compared with the lowest quartile of tHcy(<= 8.0 pmol/L;adjusted OR,1.82; 95% CI,1.20-2.75). Conclusions:The strong associations between MTHFD variants and the plasma tHcy levels and gastric cancer risk suggest, for the first time, a possible gene-environment interaction between genetic variants of folate-metabolizing genes and high tHcy levels in gastric carcinogenesis. | Wang, L. N Ke, Q Chen, W. S Wang, J. M Tan, Y. F Zhou, Y Hua, Z. L Ding, W. L Niu, J. Y Shen, J Zhang, Z. F Wang, X. R Xu, Y. H Shen, H. B Yi Xing | 2007 | 南京医科大学学报(自然科学版)2007，27，7： | 10 |
| 5 | 油炸食品与心血管病风险和全因死亡率的关系:观察性研究的荟萃分析显示文摘研究者进行了一项荟萃分析,包括剂量反应分析,以定量确定油炸食品摄入与普通成年人群心血管病风险和全因死亡率之间的关系。方法:研究者在PubMed、EMBASE和Web of Science上检索2020年4月11日之前的所有文章。应用随机效应模型估计总的相对危险度(relative risks,RR)和95%CI。结果:与最低油炸食品摄入量相比,最高摄入量者主要心血管事件的总RR(95%CI)=1.28(1.15~1.43),n=17,I^(2)=82.0%,其中前瞻性研究:1.24(1.12~1.38),n=13,I^(2)=75.7%. | 刘青(译) 练桂丽(审校) Qin P Zhang M Han M Liu D Luo X Xu L Zeng Y Chen Q Wang T Chen X Zhou Q Li Q Qie R Wu X Li Y Zhang Y Wu Y Hu D Hu F | 2021 | 中华高血压杂志2021，29，2： | 3 |
| 6 | Effects of U50,488H on transient outward and ultra-rapid delayed rectifier K+ currents in young human atrial myocytes显示文摘 | Xiao G S Zhou J J Cheung Y F | 2003 | Eur J Pharmacol2003，473，： | 2 |
| 7 | In vivo generation of dendritic cells by intramuscular codelivery of FLT3 ligand and GM-CSF plasmids 显示文摘 | Peretz Y Zhou ZF Halwani F | 2002 | Mol Ther2002，6，3： | 2 |
| 8 | Design calculations for flexure hings显示文摘 | Wu Y F Zhou Z Y | 2002 | Review of Scientific Instruments2002，73，8： | 2 |
| 9 | Distribution of time between failures of machining center based on type Ⅰ censored data显示文摘 | Dai Y Zhou Y F Jia Y Z | 2003 | Reliability Engineering and System Safety2003，79，3： | 1 |
| 10 | Combinatorial modification of multiple lignin traits in trees through multigene cotransformation 显示文摘 | Li L Zhou Y Cheng X F | 2003 | Plant Biology2003，100，8： | 1 |
| 11 | Preparation and properties of Gd3+ and Y3+ co-doped ceria-based electrolytes for intermediate temperature solid oxide fuel cells 显示文摘 | GUAN X F ZHOU H P WANG Y N | 2008 | J Alloys Compd2008，464，： | 1 |
| 12 | Mechanisms for oil depletion and enrichment on the Shijiutuo uplift, Bohai Bay Basin, China 显示文摘 | HAO F ZHOU X H ZHU Y M | 2009 | AAPG Bulletin2009，93，8： | 1 |
| 13 | Fabrication of poly- crystalline lanthanum manganite ( LaMnO3 ) nanofibers by electrospinning 显示文摘 | Zhou X F Zhao Y Cao X Y | 2008 | Materials Letters2008，62，： | 1 |
| 14 | An XYθ Mechanism actuated by one actuator 显示文摘 | Wu Y F Zhou Z Y | 2004 | Mechanism and Machine Theory2004，39，10： | 1 |
| 15 | Research on environmental-friendly anodizing process for magnesium alloys显示文摘 | LUO S L DAI L ZHOU H H CHAI L Y KUANG Y F | 2005 | Journal of Hunan University (Natural Sciences)2005，32，3： | 1 |
| 16 | Therapeutic interventions for enhancing collateral development by administration of growth factors:basic principles, early results and potential hazards 显示文摘 | EPSTEIN S E FUCHS S ZHOU Y F | 2001 | Cardiovasc Res2001，49，： | 1 |
| 17 | Size effect of AI particles on the oxidation of elecuodeposited Ni-Al composite coatings 显示文摘 | ZHOU Y PENG X WANG F | 2005 | Oxidation of Metal2005，64，： | 1 |
| 18 | Highly pathogenic porcine reproductive and respiratory syndrome, China 显示文摘 | Tong G Z Zhou Y J Hao X F | 2007 | Emerg Infect Dis2007，13，9： | 1 |
| 19 | 显示文摘 | Wang C F Zhou G W Xu Y Q | 2011 | Journal of PhysicalChemistry C2011，115，22： | 1 |
| 20 | A temporal link between the Emeishan large igneous province (SW China) and the end-Guagalupian mass extinction 显示文摘 | Zhou M F Malpas J Song X Y Robinson P T Sun M Kennedy A K Lesher C M Keays R R | 2002 | Earth arut Planetary Science Letters2002，196，： | 1 |
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