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| 1 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 2 | In-plane bistatic backward scattering from seabottom with randomly inhomogeneous sediment and rough interface显示文摘The in-plane bistatic backward scattering caused by seabottom with random inhomogeneities and rough interface is studied. This work combines the ray tube integral method of Ivakin et al. and the complex-ray/steepest descent method of Hines. For a given incident grazing angle, the theoretical expression can easily be used to calculate scattering strength for different backward scattering angles. (This is essential for modeling shallow water reverberation by the normal mode approach.) The model is tested against published scattering measurements. The frequency/angle dependence of backward scattering and effects of volume inhomogeneity parameters on backward scattering are also discussed. | PENG Zhaohui1,,ZHOU Jixun1,& ZHANG Renhe1 2 2 1.Institute of Acoustics,Chinese Academy of Sciences,Beijing 100080,China 2.School of Mechanical Engineering,Georgia Institute of Technology,Atlanta,GA 30332,USA | 2004 | Science China(Physics,Mechanics & Astronomy)2004，47，6： | 8 |
| 3 | Honokiol:a promising small molecular weight natural agent for the growth inhibition of oral squamous cell carcinoma cells显示文摘Honokiol (HNK) is a small organic molecule purified from magnolia species and has demonstrated anticancer activities in a variety of cancer cell lines; however, its effect on oral squamous cell carcinoma (OSCC) cells is unknown. We investigated the antitumor activities of HNK on OSCC cells in vitro for the first time. The inhibitory effects of HNK on the growth and proliferation of OSCC cells were demonstrated via in vitro 3-(4,5-dimethyl thiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and propidium iodide (PI) assays, and the apoptotic cells were investigated by the observation of morphological changes and detection of DNA fragmentation via PI, TdT-mediated dUTP-biotin nick end labeling (TUNEL), and DNA ladder assays, as well as flow cytometry assay. The results showed that HNK inhibited the growth and proliferation of OSCC cells in vitro in a time and dose-dependent manner. The inhibitory effect was associated with the cell apoptosis induced by HNK, evidenced by the morphological features of apoptotic cells, TUNEL-positive cells and a degradation of chromosomal DNA into small internucleosomal fragments. The study also demonstrated here that the inhibition or apoptosis mediated by 15 μg·mL-1 or 20 μg·mL-1 of HNK were more stronger compared with those of 20 μg·mL-1 5-fluorouracil (5-Fu, the control) applied to OSCC cells, when the ratio of OSCC cell numbers were measured between the treatment of different concentrations of HNK to the 5-Fu treatment for 48 h. HNK is a promising compound that can be potentially used as a novel treatment agent for human OSCC. | Xi-rui Chen Rui Lu Hong-xia Dan Ga Liao Min Zhou Xiao-yu Li Ning Ji | 2011 | International Journal of Oral Science2011，3，1： | 8 |
| 4 | The Oral Microbiome Bank of China显示文摘The human microbiome project(HMP) promoted further understanding of human oral microbes. However, research on the human oral microbiota has not made as much progress as research on the gut microbiota. Currently, the causal relationship between the oral microbiota and oral diseases remains unclear, and little is known about the link between the oral microbiota and human systemic diseases. To further understand the contribution of the oral microbiota in oral diseases and systemic diseases, a Human Oral Microbiome Database(HOMD) was established in the US. The HOMD includes 619 taxa in 13 phyla, and most of the microorganisms are from American populations. Due to individual differences in the microbiome, the HOMD does not reflect the Chinese oral microbial status. Herein, we established a new oral microbiome database—the Oral Microbiome Bank of China(OMBC,http://gffzz1f92d53390b34408hpx6k6c5bkbk96xuv.ffgz.tsg.suse.edu.cn/ombc). Currently, the OMBC includes information on 289 bacterial strains and 720 clinical samples from the Chinese population, along with lab and clinical information. The OMBC is the first curated description of a Chinese-associated microbiome; it provides tools for use in investigating the role of the oral microbiome in health and diseases, and will give the community abundant data and strain information for future oral microbial studies. | Xian Peng Xuedong Zhou Xin Xu Yuqing Li Yan Li Jiyao Li Xiaoquan Su Shi Huang Jian Xu Ga Liao | 2018 | International Journal of Oral Science2018，10，2： | 8 |
| 5 | Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells:implications in the antiproliferative response to rapamycin显示文摘 | Visner GA Lu F Zhou H | 2003 | Circulation2003，107，6： | 1 |
| 6 | Mechanisms of G1 checkpoint loss in resected early stage non-small cell lung cancer显示文摘 | Zhou JX Niehans GA Shar A | 2001 | Lung Canc- er2001，32，1： | 1 |
| 7 | Centrosome abnormal- ities and chromosome instability occur together in pre-in- vasive carcinomas 显示文摘 | Pihan GA Wallace J Zhou Y | 2003 | Cancer Res2003，63，6： | 1 |
| 8 | Analyzing antibody specificity with whole proteome microarrays 显示文摘 | Miehaud GA Salcius M Zhou F | 2003 | Nat Biotechnol2003，21，12： | 1 |
| 9 | Centrosome abnormalities and chromosome instability occur together in pre-invasive car- cinomas显示文摘 | Pihan GA Wallace J Zhou Y | 2003 | Cancer Res2003，63，6： | 1 |
| 10 | Bone marrow stem cells as a vehicle for delivery of heme oxygenase-1 gene显示文摘 | Zhou H Ramiya VK Visner GA | 2006 | Stem Cells Dev2006，15，1： | 1 |
| 11 | Mechanisms of G1checkponit loss in resected early stage non-small cell lung cancer 显示文摘 | Zhou JX Niehans GA Alexander S | 2001 | Lung Cancer2001，32，： | 1 |
| 12 | 'Plus-C' odorant-binding protein genes in two Drosophila species and the malaria mosquito Anopheles gambiae显示文摘 | Zhou JJ Huang W Zhang GA | 2004 | Gene2004，27，1： | 1 |
| 13 | Postural sway in idiopathic rapid eye movement sleep behavior disorder:a potential marker of prodromal Par- kinson's disease 显示文摘 | Chen TZ Xu GJ Zhou GA | 2014 | Brain Res2014，1559，： | 1 |
| 14 | Overexpression of soybean ubiquitin-conjugating enzyme gene GmUBC2 confers enhanced drought and salt tolerance through modulating abiotic stress-responsive gene expression in Arabidopsis显示文摘 | Zhou GA Chang RZ Qiu LJ | 2010 | Plant Mol Biol2010，72，45： | 1 |
| 15 | Centrosome abnormalities and chromosome instability occur together in preinvasive carcinomas 显示文摘 | Pihan GA Wallace J Zhou Y | 2003 | Cancer Res2003，63，6： | 1 |
| 16 | Prolonged insula activation during perception of aftertaste显示文摘 | James GA Li XB DuBois GE Zhou L Hu XP | | 0，，： | 1 |
| 17 | Mechanism s of G1 checkpo mtloss in resected early stage non-sman cell lung cancer显示文摘 | Zhou JX Niehans GA Shar A | 2001 | Lung Cancer2001，1，： | 1 |
| 18 | Breast feeding and risk for childhood obesity:doesdiabetes or obesity status matter显示文摘 | Mayer-Davis EJ Rifas-Shiman SL Zhou L Hu FB Colditz GA Gilman MW | 2006 | Diabetes Care2006，29，10： | 1 |
| 19 | Endothelial progenitor cell therapy in atherosele- rosis: a double-edged sword显示文摘 | Liu P Zhou B Ga D | 2009 | Ageing Res Rev2009，8，2： | 1 |
| 20 | THE STRUCTURE OF ASTERBATANOSIDE J FROM ASTER BATANGENSIS显示文摘THE STRUCTURE OF ASTERBATANOSIDE J FROMASTER BATANGENSIS￥YUSHAO1;BINGNANZHOU1;LONGZELIN2andGEOFFREYACORDELL2(1ShanghaiInstitu... | Shao, Y Zhou, BN Lin, LZ Cordell, GA | 1995 | Chinese Chemical Letters1995，6，3： | 1 |
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