|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Seasonal variations of stable isotope in precipitation and moisture transport at Yushu,eastern Tibetan Plateau显示文摘Precipitation δ 18O at Yushu, eastern Tibetan Plateau, shows strong fluctuation and lack of clear seasonality. The seasonal pattern of precipitation stable isotope at Yushu is apparently different from either that of the southwest monsoon region to the south or that of the inland region to the north. This different seasonal pattern probably reflects the shift of different moisture sources. In this paper, we present the spatial comparison of the seasonal patterns of precipitation δ 18O, and calculate the moisture transport flux by using the NCAR/NCEP reanalysis data. This allows us to discuss the relation between moisture transport flux and precipitation δ 18O. This study shows that both the southwest monsoon from south and inland air mass transport from north affected the seasonal precipitation δ 18O at Yushu, eastern Tibetan Plateau. Southwest monsoon brings the main part of the moisture, but southwest transport flux is weaker than in the southern part of the Tibetan Plateau. However, contribution of the inland moisture from north or local evaporation moisture is enhanced. The combined effect is the strong fluctuation of summer precipitation δ 18O at Yushu and comparatively poor seasonality. | TIAN LiDe MA LingLong YU WuSheng LIU ZhongFang YIN ChangLiang ZHAO ZhongPing TANG Wei WANG Yu | 2008 | Science China Earth Sciences2008，51，8： | 9 |
| 2 | Temporal and spatial variations of δ^18O in precipitation of the Yarlung Zangbo River Basin显示文摘这份报纸在 2005 在四个车站(Lhaze, Nugesha, Yangcun 和 Nuxia ) 在降水基于未 1 8O 的变化在 Yarlung Zangbo 河盆的降水揭示稳定的同位素的时间、空间的变化。结果证明降水的未 1 8O 在 Yarlung Zangbo 河盆有不同季节的变化。未 1 8O 的更高的价值在季风降水以前在春天发生,并且更低的价值发生在季风降水期间。从空间变化,沿着 Yarlung Zangbo 河山谷在潮湿运输期间与高度效果和 rainout 处理,降水的 18O 逐渐地被弄空。因此,降水的未 1 8O 逐渐地减少从对下游在上游,并且在降水的未 1 8O 的差错率为二个原因是约 0.34 鈥 ? 100m 和 0.7 鈥 ? 100km。在季风降水期间,在降水的未 1 8O 的空间变化被数量效果在大规模统治摘要的状况。 | LIU Zhongfang TIAN Lide YAO Tandong GONG Tongliang YIN Changliang YU Wusheng | 2007 | Journal of Geographical Sciences2007，17，3： | 7 |
| 3 | An effective strategy to establish a male sterility mutant mini-library by CRISPR/Cas9-mediated knockout of anther-specific genes in rice显示文摘Male sterility(MS),characterized by functional defects in male organs or gametes,is an important agronomic trait for hybrid seed production,especially for self-pollinated crops such as rice(Oryza sativa L)(Chen and Liu,2014).Spontaneous MS mutants are rare and difficult to maintain in nature,thus limiting basicresearch and breeding.Artificial mutants are typically generated by physical,chemical,or biological mutagenesis(Wei et al,2013).Recently developed genome editing systems such as CRISPR/Cas9 allow efficient and timesaving knockout of endogenous genes at specific sites(Smith et al,2000;Moscou and Bogdanove,2009;Gasiunas et al.,2012). | Kun Ma Jingluan Han Yu Hao Zhongfang Yang Junyu Chen Yao-Guang Liu Qinlong Zhu Letian Chen | 2019 | Journal of Genetics and Genomics2019，46，5： | 6 |
| 4 | A study of soil organic carbon distribution and storage in the Northeast Plain of China显示文摘采用联合起来的土壤碳数量(USCA ) 途径,土壤碳存储基于在 20042006 进行的多种用途的地区性的 Geochemical 调查(MRGS ) 越过中国的东北平原被计算。结果显示在表层土(00.2 m ) 的器官的碳(SOC ) 存储,心土(01 m ) 和深土壤(01.8 m ) 是的土壤有 3327.8 t/km2, 12,904.7 t/km2 和 16,157.5 t/km2 的密度的 768.1 山, 2978.4 山和 3729.2 山分别地。而土壤碳密度从东北平原(辽宁)的南部的区域显示出一个清楚的增加趋势,这些价值以表层土特别地与国家一般水准一致,到中间(吉林)和北平原( Heilongjiang )碳密度,从 2284.2 增加了,到 3436.7 和 3861.5 t/km2 ,分别地。与在 19841986 从第二国家土壤调查获得的碳数据(SNSS ) 相比,从 MRGS 的表层土 SOC 存储值被发现由 320.59 山(29.4%) 减少了,与在 20 年的 16.0 山(l.73%) 的平均年度衰落。在平原的南部、中间、北的区域,分别地,土壤碳密度为整个平原与 1389.0 t/km2 的平均价值由 1060.6 t/km2, 1646.4 t/km2 和 1300.2 t/km2 减少了。这些调查结果显示在土壤碳密度的减少根据不同生态系统和陆地使用类型变化了。因此,土壤碳密度的比率被计算以便学习碳,并且进一步探索分发特征在生态系统之间的动态平衡,以及 SOC 的隐遁潜力。 | Xiaohuan Xi Zhongfang Yang Yujun Cui Shumei Sun Chengguang Yu Min Li | 2011 | Geoscience Frontiers2011，2，2： | 5 |
| 5 | The susceptibility of T5-TG12 of theCFTR gene in chronic bronchitis occurrence in a Chinese population in Jiangsu province,China显示文摘Mutations in the cystic fibrosis transmembrane conductance regulator(CFTR) gene have been implicated in the onset of cystic fibrosis and other clinical respiratory disorders.In the present study,we investigated the role of CFTR variations,poly-T,TG-repeats,and M470V in susceptibility to bronchial asthma and chronic bronchitis in a Chinese population in Jiangsu province,China.A total of 72 bronchial asthma patients,68 chronic bronchitis patients,and 117 healthy subjects were included in this study.The Tn-TGm haplotype was sequenced and the CFTR variant M470V was detected using restriction fragment length polymorphism(RFLP).We found that the frequency of T5-TG12-V470 in chronic bronchitis patients was 0.07%,which was notably higher than that in healthy subjects(0.01%) and bronchial asthma patients(0.04%).Thus,the presence of the T5-TG12 haplotype of the CFTR gene is likely to play a role in the development and progression of respiratory conditions,such as chronic bronchitis. | Ping Wang Satoru Naruse Hong Yin Zhongfang Yu Tianqu Zhuang Wei Ding Yanmin Wu Muxin Wei | 2012 | The Journal of Biomedical Research2012，26，6： | 4 |
| 6 | Spatial analysis of land use change effect on soil organic carbon stocks in the eastern regions of China between 1980 and 2000显示文摘Spatial distributions of 0-20 cm soil carbon sources/sinks caused by land use changes from the year 1980 to 2000 in an area of 2.97 × 10~6 km^2 in eastern China were investigated using a land use dataset from a recent soil geochemical survey.A map of soil carbon sources/sinks has been prepared based on a spatial analysis scheme with GIS.Spatial statistics showed that land use changes had caused 30.7 ± 13.64 Tg of surface soil organic carbon loss,which accounts for 0.33%of the total carbon storage of 9.22 Pg.The net effect of the carbon source was estimated to be ~ 71.49 Tg soil carbon decrease and ~40.80 Tg increase.Land use changes in Northeast China(NE) have the largest impact on soil organic carbon storage compared with other regions.Paddy fields,which were mainly transformed into dry farmland in NE,and constructed land in other regions,were the largest carbon sources among the land use types.Swamp land in NE was also another large soil carbon source when it was transformed into dry farmland or paddy fields.Dry farmland in the NE region formed the largest soil organic carbon sink,as some were transformed into paddy fields,forested land,and other land use types with high SOCD. | Xueqi Xia Zhongfang Yang Yuan Xue Xin Shao Tao Yu Qingye Hou | 2017 | Geoscience Frontiers2017，8，3： | 3 |
| 7 | The Changes in Guilin Paddy Soil Organic Matter and Rice Yield under Long-Term Fertilization显示文摘Rational fertilization is an important measure to increase crop yield and soil fertility. Through analysis,this paper aims to master the change characteristics of soil organic matter and rice yield under different fertilizer treatments,in order to provide an important reference for the sustainable use of soil and effective fertilization. Long-term( 19 years) rice crop rotation experiments in waterloggogenic paddy soil were conducted to investigate the change trend of crop grain yield and soil organic matter with time,reveal the dynamic characteristics and relationship between main fertility factors and crop yields using comparative analysis at three sites with conventional fertilization and non-fertilization in Guilin. The results showed that compared with previous years,the rice yield increased by 53% under the fertilization treatment and degreased by 66% under the control. Over the years,the average soil organic matter( SOM) content under fertilization treatment was 23% higher than under CK treatment. This indicates that chemical fertilizer and organic manure application can increase the rice yield and soil organic matter,and high rice yield can be attributed to the SOM increase. | Qiuliang YU Zheng TANG Zhongfang LI Chunlan CHEN Xiaoxian TANG Yanli LIN | 2016 | Asian Agricultural Research2016，8，3： | 2 |
| 8 | Effects of Coupling Treatment of Acid and Aluminum under Soilless Culture on Water Content of Ginkgo biloba L.显示文摘In this experiment,two-factor 7-level uniform design scheme was applied.Separate treatment of each factor was performed for single effect test.Then,it analyzed the effects of acid and aluminum stress under soilless culture on the water content of plant during the growth of Ginkgo biloba L.seedlings,so as to provide a theoretical basis for studying the connection between plant water and physiological stress.The results showed that the water content of G.biloba plants declined with the decrease of p H,but the water content of G.biloba plants declined with the increase in the concentration of aluminum treatment,indicating that the stronger the acid and aluminum stress,the lower the water content of the plants,affecting the normal absorption of water content of G.biloba plants,accordingly leading to lack of water.According to the analysis of the degree of influence on the water content,p H is the first factor influencing the growth of G.biloba plants.If p H is lower than 3.5,G.biloba plants will not growth,while p H is higher than 5.0,aluminum has no significant effect on the water content of G.biloba plants.In conclusion,the water content of G.biloba plants can be used as an essential indicator for acid and aluminum stress. | Qiuliang YU Huilan SU Chunlan CHEN Zhongfang LI | 2018 | Asian Agricultural Research2018，10，7： | 1 |
| 9 | Effects of Soil Properties on the Transfer of Cadmium from Soil to Wheat in the Yangtze River Delta Region, China—a Typical Industry–Agriculture Transition Area显示文摘 | Cheng Wang Junfeng Ji Zhongfang Yang Lingxiao Chen Patrick Browne Ruilian Yu | 2012 | Biological Trace Element Research2012，，2： | 1 |
| 10 | The origin and geochemical cycle of soil selenium in a Se-rich area of China显示文摘 | Tao Yu Zhongfang Yang Yaoyao Lv Qingye Hou Xueqi Xia Haiyan Feng Meng Zhang Lixin Jin Zezhong Kan | 2013 | Journal of Geochemical Exploration2013，，： | 1 |
| 11 | Annual net input fluxes of heavy metals of the agro-ecosystem in the Yangtze River delta, China显示文摘 | Qingye Hou Zhongfang Yang Junfeng Ji Tao Yu Guoguang Chen Juan Li Xueqi Xia Ming Zhang Xuyin Yuan | 2013 | Journal of Geochemical Exploration2013，，： | 1 |
| 12 | Seasonal deuterium excess in Nagqu precipitation: influence of moisture transport and recycling in the middle of Tibetan Plateau显示文摘 | Zhongfang Liu Lide Tian Tandong Yao Wusheng Yu | 2008 | Environmental Geology2008，，7： | 1 |
| 13 | Development of a novel real-time RT-PCR assay with LUX primer for the detection of swine transmissible gastroenteritis virus显示文摘 | Ru Chen Weiming Huang Zhixiong Lin Zhongfang Zhou Haiqiong Yu Daozhong Zhu | 2004 | Journal of Virological Methods2004，，1： | 1 |
| 14 | Resonance Rayleigh scattering method for the determination of polyvinylpyrrolidone using eosin Y as the probe显示文摘 | Lihong Yu Zhongfang Liu Xiaoli Hn | 2010 | Mikrochimica Acta2010，169，34： | 1 |
| 15 | Phenolic com- pounds in Chinese purple yam and change during vacuum frying 显示文摘 | FANG Zhongfang WU Dan YU Dong | 2011 | Food Chemistry2011，128，： | 1 |
| 16 | Tungstate ion resonance Rayleigh scattering method for determination of basic triphenylmethane dyes显示文摘In a pH 4.2-6.0 HAc-NaAc buffer medium,the resonance Rayleigh scattering intensities of separate basic triphenylmethane dyes,such as methyl violet (MV),ethyl violet (EV),crystal violet (CV),methyl green (MeG),iodine green (IG),malachite green (MG),light green (LG),and tungstate ion solution,are very weak,but when these cationic dyes react with the tungstate ion (WO 42-) to form ion-association complexes,their RRS are enhanced sharply and new RRS spectra appear.The reaction products of methyl violet,ethyl violet,and crystal violet with WO 42-have similar spectral characteristics and there are two strong RRS peaks at 330 nm and 560 nm.The reaction products of methyl green,iodine green,malachite green,light green with WO 42-have similar spectral characteristics and there are three RRS peaks at about 335 nm,450 nm and 580 nm.The sensitivities of seven kinds of reaction products show a sequence of malachite green>light green>crystal violet>ethyl violet>methyl green>iodine green>methyl violet.The linear ranges and detection limits of the above seven systems are 0.06-2.78 μg mL-1 and 18.1 ng mL-1 (MG),0.08-4.83 μg mL-1 and 22.6 ng mL-1 (BG),0.10-4.90 μg mL-1 and 31.4 ng mL-1 (CV),0.14-2.95 μg mL-1 and 40.5 ng mL-1 (EV),0.17-3.70 μg mL-1 and 50.2 ng mL-1 (MeG),0.22-5.70 μg mL-1 and 67.1 ng mL-1 (IG),and 0.25-7.30 μg mL-1 and 76.3 ng mL-1 (MV).A sensitive,simple and fast RRS method for the determination of basic triphenylmethane dyes using the tungstate ion as the probe has been developed.The method is applicable to the determination of malachite green residues in fish flesh. | YU LiHong,LIU ZhongFang,HU XiaoLi,KONG Ling & LIU ShaoPu School of Chemistry and Chemical Engineering Key Laboratory on Luminescence and Real-Time Analysis,Ministry of Education,Southwest University,Chongqing 400715,China | 2010 | Chinese Science Bulletin2010，55，8： | 0 |
| 17 | Breaking the responsivity-speed dilemma of a-GaO_(x) photodetector by alternating gate modulation显示文摘The gallium oxide(Ga_(2)O_(3))based photodetectors are usually confronted with the typical challenge of the responsivity-speed(RS)dilemma,namely high photocurrent induces a long decay time,as shown in Figure 1(a).The RS dilemma involves a trade-off issue,which is independent of photoelectric materials. | Zhongfang ZHANG Pengju TAN Xiaohu HOU Xiaolan MA Mengfan DING Shunjie YU Guangwei XU Xiaolong ZHAO Shibing LONG | 2023 | Science China(Information Sciences)2023，66，12： | 0 |
| 18 | Standardized neutralization antibody analytical procedure for clinical samples based on the AQbD concept显示文摘Dear Editor,Vaccination is an effective strategy for controlling the COVID-19 pandemic and reducing the number of cases of hospitalization and deaths.1 Neutralizing antibody(Ntab)is one of the key indicators for evaluating the effectiveness of COVID-19 vaccines.2 Over 40 COVID-19 vaccines have been approved for emergency use,marketing,or marketing with conditions,and the available Ntab data from clinical trials have been published. | Jianyang Liu Yu Bai Mingchen Liu Dejiang Tan Jing Li Zhongfang Wang Zhenglun Liang Miao Xu Junzhi Wang Qunying Mao | 2023 | Signal Transduction and Targeted Therapy2023，8，5： | 0 |
| 19 | Trogocytosis of CAR molecule regulates CAR-T cell dysfunction and tumor antigen escape显示文摘Chimeric antigen receptor(CAR)T-cell therapy has demonstrated clinical response in treating both hematologic malignancies and solid tumors.Although instances of rapid tumor remissions have been observed in animal models and clinical trials,tumor relapses occur with multiple therapeutic resistance mechanisms.Furthermore,while the mechanisms underlying the long-term therapeutic resistance are well-known,short-term adaptation remains less understood.However,more views shed light on short-term adaptation and hold that it provides an opportunity window for long-term resistance.In this study,we explore a previously unreported mechanism in which tumor cells employ trogocytosis to acquire CAR molecules from CAR-T cells,a reversal of previously documented processes.This mechanism results in the depletion of CAR molecules and subsequent CAR-T cell dysfunction,also leading to short-term antigen loss and antigen masking.Such type of intercellular communication is independent of CAR downstream signaling,CAR-T cell condition,target antigen,and tumor cell type.However,it is mainly dependent on antigen density and CAR sensitivity,and is associated with tumor cell cholesterol metabolism.Partial mitigation of this trogocytosis-induced CAR molecule transfer can be achieved by adaptively administering CAR-T cells with antigen density-individualized CAR sensitivities.Together,our study reveals a dynamic process of CAR molecule transfer and refining the framework of clinical CAR-T therapy for solid tumors. | You Zhai Yicong Du Guanzhang Li Mingchen Yu Huimin Hu Changqing Pan Di Wang Zhongfang Shi Xu Yan Xuesong Li Tao Jiang Wei Zhang | 2024 | Signal Transduction and Targeted Therapy2024，9，1： | 0 |
| 20 | Innate immune imprints in SARS-CoV-2 Omicron variant infection convalescents显示文摘SARS-CoV-2 Omicron variant infection generally gives rise to asymptomatic to moderate COVID-19 in vaccinated people.The immune cells can be reprogrammed or“imprinted”by vaccination and infections to generate protective immunity against subsequent challenges.Considering the immune imprint in Omicron infection is unclear,here we delineate the innate immune landscape of human Omicron infection via single-cell RNA sequencing,surface proteome profiling,and plasma cytokine quantification.We found that monocyte responses predominated in immune imprints of Omicron convalescents,with IL-1β-associated and interferon(IFN)-responsive signatures with mild and moderate symptoms,respectively.Low-density neutrophils increased and exhibited IL-1β-associated and IFN-responsive signatures similarly.Mild convalescents had increased blood IL-1β,CCL4,IL-9 levels and PI3+neutrophils,indicating a bias to IL-1βresponsiveness,while moderate convalescents had increased blood CXCL10 and IFN-responsive monocytes,suggesting durative IFN responses.Therefore,IL-1β-or IFN-responsiveness of myeloid cells may indicate the disease severity of Omicron infection and mediate post-COVID conditions. | Zhiqing Li Xiaosu Chen Junyan Dan Tianju Hu Ye Hu Shuxun Liu Yangyang Chai Yansong Shi Jian Wu Hailai Ni Jiaqi Zhu Yanfeng Wu Nan Li Yizhi Yu Zhongfang Wang Jincun Zhao Nanshan Zhong Xianwen Ren Zhongyang Shen Xuetao Cao | 2022 | Signal Transduction and Targeted Therapy2022，7，12： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员