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| 1 | Neuronal apoptosis in cerebral ischemia/reperfusion area following electrical stimulation of fastigial nucleus显示文摘Previous studies have indicated that electrical stimulation of the cerebellar fastigial nucleus in rats may reduce brain infarct size, increase the expression of Ku70 in cerebral ischemia/ reperfusion area, and decrease the number of apoptotic neurons. However, the anti-apoptotic mechanism of Ku70 remains unclear. In this study, fastigial nucleus stimulation was given to rats 24, 48, and 72 hours before cerebral ischemia/reperfusion injury. Results from the electrical stimulation group revealed that rats exhibited a reduction in brain infarct size, a significant increase in the expression of Ku70 in cerebral ischemia/reperfusion regions, and a decreased number of terminal deoxynucleotidyl transferase dUTP nick end labeling(TUNEL)-positive cells. Double immunofluorescence staining revealed no co-localization of Ku70 with TUNEL-positive cells. However, Ku70 partly co-localized with Bax protein in the cytoplasm of rats with cerebral ischemia/reperfusion injury. These findings suggest an involvement of Ku70 with Bax in the cytoplasm of rats exposed to electrical stimulation of the cerebellar fastigial nucleus, and may thus provide an understanding into the anti-apoptotic activity of Ku70 in cerebral ischemia/reperfusion injury. | Jingli Liu Jinpin Li Yi Yang Xiaoling Wang Zhaoxia Zhang Lei Zhang | 2014 | Neural Regeneration Research2014，9，7： | 26 |
| 2 | Ecological water demand of natural vegetation in the lower Tarim River显示文摘我们在西方的中国在 Tarim 河的更低的活动范围估价了在土壤潮湿,地下水深度,和植物种类差异之间的关系,由分析从 25 的领域数据监视越过八个学习地点和 25 永久植被调查的井阴谋。地下水深度,土壤潮湿和植物种类差异是密切相关的,这被注意。批评的井的水深度是在 Tarim 河的更低的活动范围的五米,这被证明了。我们每个月由用 Qunk 和 Averyanov 公式平均井的蒸发的二结果获得了不同地下水层次的吝啬的井的蒸发。与不同地下水深度基于不同植被类型和面积,在 2005 的自然植被的全部的生态的水需求(EWD ) 是 2. | YE Zhaoxia CHEN Yaning LI Weihong | 2010 | Journal of Geographical Sciences2010，20，2： | 23 |
| 3 | Coordinated Scheduling of Energy Resources for Distributed DHCs in an Integrated Energy Grid显示文摘As more and more distributed renewable energy resources connected to electric power grids,the conventional power system evolves into an integrated energy grid(IEG)in order to satisfy various types of energy demands.This paper proposes a model of the coordinated scheduling of energy resources(CSoERs)for distributed district heating and cooling systems(DHCs)in an IEG.The model takes into consideration both the dispatchable grid-connected generators and distributed renewable energy resources,such as wind energy,solar energy and natural gas.The objective is to minimize the operation costs in the IEG in order to satisfy not only the electrical loads but also the heating loads and cooling loads.Furthermore,an energy storage system for heating loads and cooling loads is also developed in the DHCs to improve the operation reliability in the distributed DHCs.Detailed simulation studies are carried out to verify the effectiveness of the CSoERs under two different operation scenarios:grid-connected scenario and stand-alone scenario.Simulation results demonstrate that the performance of the CSoERs contributes to significant energy saving and reliability operation in both grid-connected scenario and standalone scenario in the IEG. | Qinghua Wu Jiehui Zheng Zhaoxia Jing | 2015 | CSEE Journal of Power and Energy Systems2015，1，1： | 21 |
| 4 | Advances in Cloud Physics and Weather Modification in China显示文摘The capabilities of cloud-resolving numerical models, observational instruments and cloud seeding have improved greatly over recent years in China. The subject of this review focuses on the main progresses made in China in the areas of cloud modeling, field observations, aerosol–cloud interactions, the effects of urbanization on cloud and precipitation, and weather modification.Well-equipped aircraft and ground-based advanced Doppler and polarized radars have been rapidly applied in cloudseeding operations. The combined use of modern techniques such as the Global Positioning System, remote sensing, and Geographical Information Systems has greatly decreased the blindness and uncertainties in weather-modification activities.Weather-modification models based on state-of-the-art cloud-resolving models are operationally run at the National Weather Modification Centre in China for guiding weather-modification programs.Despite important progress having been made, many critical issues or challenges remain to be solved, or require stronger scientific evidence and support, such as the chain of physical events involved in the effects induced by cloud seeding. Current important progresses in measurements and seeding techniques provide the opportunity and possibility to reduce these deficiencies. Long-term scientific projects aimed at reducing these key uncertainties are extremely urgent and important for weather-modification activities in China. | GUO Xueliang FU Danhong LI Xingyu HU Zhaoxia LEI Henchi XIAO Hui HONG Yanchao | 2015 | Advances in Atmospheric Sciences2015，32，2： | 16 |
| 5 | A study of the mechanism of enhancing oil recovery using supercritical carbon dioxide microemulsions显示文摘Supercritical carbon dioxide (scCO 2) microemulsion was formed by supercritical CO 2 , H 2 O, sodium bis(2-ethylhexyl) sulfosuccinate (AOT, surfactant) and C 2 H 5 OH (co-surfactant) under pressures higher than 8 MPa at 45 oC. The fundamental characteristics of the scCO 2 microemulsion and the minimum miscibility pressure (MMP) with Daqing oil were investigated with a high-pressure falling sphere viscometer, a high-pressure interfacial tension meter, a PVT cell and a slim tube test. The mechanism of the scCO 2 microemulsion for enhancing oil recovery is discussed. The results showed that the viscosity and density of the scCO 2 microemulsion were higher than those of the scCO 2 fluid at the same pressure and temperature. The results of interfacial tension and slim tube tests indicated that the MMP of the scCO 2 microemulsion and crude oil was lower than that of the scCO 2 and crude oil at 45 oC. It is the combined action of viscosity, density and MMP which made the oil recovery efficiency of the scCO 2 microemulsion higher than that of the scCO 2 fluid. | Dong Zhaoxia Li Yi Lin Meiqin Li Mingyuan | 2013 | Petroleum Science2013，10，1： | 12 |
| 6 | Modeling xeroderma pigmentosum associated neurological pathologies with patients-derived iPSCs显示文摘干皮病 pigmentosum (XP ) 是联系 XP 的基因的变化引起的一组基因混乱,导致 DNA 修理的缺陷。XP 病人经常展出神经病学的退化,而是内在的机制是未知的,部分地由于合适的疾病模型的缺乏。这里,我们产生了包括 XPA, XPB, XPC, XPG,和 XPV 在五不同 XP 基因怀有变化的病人特定的导致的 pluripotent 干细胞(iPSCs ) 。这些 iPSCs 进一步被区分到神经房间,并且他们到 DNA 损坏应力的危险性被调查。在神经干细胞(NSC ) 或神经原的 XPA 的变化导致了严重 DNA 损坏修理缺点,并且有变异的 XPA 的这些神经房间对 DNA 导致损坏的 apoptosis 过分敏感。因此, XP 变异的神经房间代表珍贵工具在 XP 病人澄清神经病学的畸形的分子的机制。 | Lina Fu Xiuling Xu Ruotong Ren Jun Wu Weiqi Zhang Jiping Yang Xiaoqing Ren Si Wang Yang Zhao Liang Sun Yang Yu Zhaoxia Wang Ze Yang Yun Yuan Jie Qiao Juan Carlos Izpisua Belmonte Jing Qu Guang-Hui Liu | 2016 | Protein & Cell2016，7，3： | 11 |
| 7 | CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs显示文摘 | Lixia Wang Fei Yi Lina Fu Jiping Yang Si Wang Zhaoxia Wang Keiichiro Suzuki Liang Sun Xiuling Xu Yang Yu Jie Qiao Juan Carlos Izpisua Belmonte Ze Yang Yun Yuan Jing Qu Guang-Hui Liu | 2017 | Protein & Cell2017，8，5： | 10 |
| 8 | Influence of surfactants used in surfactant-polymer flooding on the stability of Gudong crude oil emulsion显示文摘The influences of an anionic-nonionic composite surfactant and petroleum sulfonate, used in surfactant-polymer flooding in Shengli Gudong oilfield, East China, on the interfacial properties of Gudong crude model oil and synthetic formation water was studied by measuring interfacial tension, interfacial viscoelasticity and Zeta potential. The in? uence of the surfactants on the stability of Gudong water-in-oil (W/O) and oil-in-water (O/W) emulsions was evaluated by separating water from the W/O emulsion and residual oil in the aqueous phase of the O/W emulsion respectively. The results showed that the two kinds of surfactants, namely anionic-nonionic composite surfactant and petroleum sulfonate, are both able to decrease the interfacial tension between the oil phase and the aqueous phase and increase the surface potential of the oil droplets dispersed in the O/W emulsion, which can enhance the stability of the W/O and O/W crude oil emulsions. Compared with petroleum sulfonate, the anionic-nonionic composite surfactant is more interfacially active and able to enhance the strength of the interfacial film between oil and water, hence enhance the stability of the W/O and O/W emulsions more effectively. | Dong Zhaoxia Lin Meiqin Wang Hao Li Mingyuan | 2010 | Petroleum Science2010，7，2： | 10 |
| 9 | Expression of SoxC Transcription Factors during Zebrafish Retinal and Optic Nerve Regeneration显示文摘The SoxC transcription factors(Sox4,Sox11,and Sox12) play important roles in the development of the vertebrate eye and retina. However,their expression and function during retinal and optic nerve regeneration remain elusive. In this study,we investigated the expression and possible functions of the SoxC genes after retinal and optic nerve injury in adult zebrafish. We found that among the five SoxC members,Sox11b was strongly induced in BrdU-positive cells in the inner nuclear layer(INL) after retinal injury,and morpholino-mediated Sox11b-knockdown significantly reduced the number of proliferating cells in the INL at 4 days post-injury. After optic nerve lesion,both Sox11a and Sox11b were strongly expressed in retinal ganglion cells(RGCs),and knockdown of both Sox11a and Sox11b inhibited RGC axon regrowth in retinal explants. Our study thus uncovered a novel expression pattern of SoxC family genes after retinal and optic nerve injury,and suggests that they have important functions during retinal and optic nerve regeneration. | Zhaoxia Mu Shuqiang Zhang Chunjiao He Haitao Hou Dong Liu Nan Hu Hui Xu | 2017 | Neuroscience Bulletin2017，33，1： | 9 |
| 10 | Dispersion polymerization of anionic polyacrylamide in an aqueous salt medium显示文摘Anionic polyacrylamide dispersions were prepared by dispersion polymerization in an aqueous salt medium, using acrylamide(AM) and acrylic acid(AA) as monomers and anionic polyelectrolytes as stabilizer. Effects of salt concentration, and molecular weight and concentration of stabilizers on the stability of the dispersions were investigated using a HAAKE rheometer and optical microscopy. The results showed that stable anionic polyacrylamide dispersions, consisting of smooth, spherical, polydisperse particles, could be obtained under the conditions of salt concentration ranging from 26 wt% to 30 wt%, concentration of stabilizers from 1.2 wt% to 1.8 wt%, and intrinsic viscosity of stabilizers from 2.98 dL·g-1 to 3.74 dL·g-1 . The apparent viscosity of the stable dispersions changed very little with the shear rate, showing Newton fluid behavior. | Lu Jiao Peng Bo Li Mingyuan Lin Meiqin Dong Zhaoxia | 2010 | Petroleum Science2010，7，3： | 8 |
| 11 | Neural Network Predictive Control of Variable-pitch Wind Turbines Based on Small-world Optimization Algorithm显示文摘通过将混沌映射用于产生初始节点集和进行算子构造,提出一种新的基于实数编码的混沌小世界优化算法。采用4种算法对多例复杂函数的优化问题进行仿真试验,表明所提算法具有能够有效避免陷入局部极小值、快速搜索到最优值的能力。将上述方法应用于变桨距风电机组启动并网时的转速控制,提出一种基于混沌小世界优化算法的神经网络预测控制策略,其预测模型由基于现场数据的神经网络模型建立。仿真与实际测试结果表明,该系统可以根据风速扰动提前预测电机的转速变化,使控制器超前动作,保证系统输出跟踪参考轨迹的方向稳步改变,确保风电机组平稳并网。 | WANG Shuangxin LI Zhaoxia LIU Hairui | 2012 | 中国电机工程学报2012，32，30： | 8 |
| 12 | Actual evapotranspiration of subalpine meadows in the Qilian Mountains, Northwest China显示文摘As a main component in water balance,evapotranspiration(ET)is of great importance for water saving,especially in arid and semi-arid areas.In this study,the FAO(Food and Agriculture Organization)Penman-Monteith model was used to estimate the magnitude and temporal dynamics of reference evapotranspiration(ET0)in 2014 in subalpine meadows of the Qilian Mountains,Northwest China.Meanwhile,actual ET(ETc)was also investigated by the eddy covariance(EC)system.Results indicated that ETc estimated by the EC System was 583 mm,lower than ET0(923 mm)estimated by the FAO Penman-Monteith model in 2014.Moreover,ET0 began to increase in March and reached the peak value in August and then declined in September,however,ETc began to increase from April and reached the peak value in July,and then declined in August.Total ETc and ET0 values during the growing season(from May to September)were 441 and 666 mm,respectively,which accounted for 75.73%of annual cumulative ETc and 72.34%of annual cumulative ET0,respectively.A crop coefficient(kc)was also estimated for calculating the ETc,and average value of kc during the growing season was 0.81(ranging from 0.45 to 1.16).Air temperature(Ta),wind speed(u),net radiation(Rn)and soil temperature(Ts)at the depth of 5 cm and aboveground biomass were critical factors for affecting kc,furthermore,a daily empirical kc equation including these main driving factors was developed.Our result demonstrated that the ETc value estimated by the data of kc and ET0 was validated and consistent with the growing season data in 2015 and 2016. | GAO Yunfei ZHAO Chuanyan Muhammad W ASHIQ WANG Qingtao RONG Zhanlei LIU Junjie MAO Yahua GUO Zhaoxia WANG Wenbin | 2019 | Journal of Arid Land2019，11，3： | 8 |
| 13 | Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells显示文摘Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy(CADASIL)is a rare hereditary cerebrovascular disease caused by a NOTCH3 mutation.However,the underlying cellular and molecular mechanisms remain unidentified.Here,we generated non-integrative induced pluripotent stem cells(iPSCs)from fibroblasts of a CADASIL patient harboring a heterozygous NOTCH3 mutation(c.3226C>T,p.R1076C).Vascular smooth muscle cells(VSMCs)differentiated from CADASIL-specific iPSCs showed gene expression changes associated with disease phenotypes,including activation of the NOTCH and NF-kB signaling pathway,cytoskeleton disorganization,and excessive cell proliferation.In comparison,these abnormalities were not observed in vascular endothelial cells(VECs)derived from the patients iPSCs.Importantly,the abnormal upregulation of NF-kB target genes in CADASIL VSMCs was diminished by a NOTCH pathway inhibitor,providing a potential therapeutic strategy for CADASIL.Overall,using this iPSCbased disease model,our study identified clues for studying the pathogenic mechanisms of CADASIL and developing treatment strategies for this disease. | Chen Ling Zunpeng Liu Moshi Song Weiqi Zhang Si Wang Xiaoqian Liu Shuai Ma Shuhui Sun Lina Fu Qun Chu Juan Carlos Izpisua Belmonte Zhaoxia Wang Jing Qu Yun Yuan Guang-Hui Liu | 2019 | Protein & Cell2019，10，4： | 7 |
| 14 | Molecular Framework for Auxin-Controlled Hlomeostasis-of Shoot Stem Cells in Arabidopsis显示文摘 | Linjie Luo Jian Zengg Haijun Wu Zhaoxia Tian Zhong Zhao | 2018 | Molecular Plant2018，11，7： | 7 |
| 15 | Optimal Operation of Integrated Energy Systems Subject to Coupled Demand Constraints of Electricity and Natural Gas显示文摘This paper proposes a hybrid multi-objective optimization and game-theoretic approach(HMOGTA)to achieve the optimal operation of integrated energy systems(IESs)consisting of electricity and natural gas(E&G)utility networks,multiple distributed energy stations(DESs),and multiple energy users(EUs).The HMOGTA aims to solve the coordinated operation strategy of the electricity and natural gas networks considering the demand characteristics of DESs and EUs.In the HMOGTA,a hierarchical Stackelberg game model is developed for generating equilibrium strategies of DESs and EUs in each district energy network(DEN).Based on the game results,we obtain the coupling demand constraints of electricity and natural gas(CDCENs)which reflect the relationship between the amounts and prices of electricity and cooling(E&C)that DESs purchase from utility networks.Furthermore,the minimization of conflicting costs of E&G networks considering the CDCENs are solved by a multi-objective optimization method.A case study is conducted on a test IES composed of a 20-node natural gas network,a modified IEEE 30-bus system,and 3 DENs,which verifies the effectiveness of the proposed HMOGTA to realize fair treatment for all participants in the IES. | Yingjie Qin Lilan Wu Jiehui Zheng Mengshi Li Zhaoxia Jing Q.H.Wu Xiaoxin Zhou Feng Wei | 2020 | CSEE Journal of Power and Energy Systems2020，6，2： | 7 |
| 16 | Decentralized Event-Triggered Average Consensus for Multi-Agent Systems in CPSs with Communication Constraints显示文摘The paper investigates decentralized event-triggered average consensus problem for multi-agent systems in cyberphysical systems(CPSs) with communication constraints.To reduce communication burden and improve the communication efficiency of multi-agent systems in CPSs,event-trigger is distributed at subsystem/agent level.A multi-agent system is then modeled as a reduced dimension hybrid system by taking into account decentralized event-triggered mechanism,communication delays and data dropouts within one framework.Some sufflcient conditions for average consensus of each agent and an upper bound of communication delay and maximal allowable number of successive data dropouts(MANSD) are obtained,which can conveniently provide the relationship between the triggering parameters,communication constraints and the system stability.Specially,the quantitative relationship between the triggering parameters,MANSD and the system stability is derived.Finally,simulation results are given to illustrate the effectiveness of the proposed method. | Zhaoxia Wang Minrui Fei Dajun Du Min Zheng | 2015 | IEEE/CAA Journal of Automatica Sinica2015，2，3： | 6 |
| 17 | Sizing optimization for island microgrid with pumped storage system considering demand response显示文摘Currently, small islands are facing an energy supply shortage, which has led to considerable concern.Establishing an island microgrid is a relatively good solution to the problem. However, high investment costs restrict its application. In this paper, micro pumped storage(MPS) is used as an energy storage system(ESS) for islands with good geographical conditions, and deferrable appliance is treated as the virtual power source which can be used in the planning and operational processes.Household acceptance of demand response(DR) is indicated by the demand response participation degree(DRPD), and a sizing optimization model for considering the demand response of household appliances in an island microgrid is proposed. The particle swarm optimization(PSO) is used to obtain the optimal sizing of all major devices. In addition, the battery storage(BS) scheme is used as the control group. The results of case studies demonstrate that the proposed method is effective, and the DR of deferrable appliances and the application of MPS can significantly reduce island microgrid investment.Sensitivity analysis on the total load of the island and the water head of the MPS are conducted. | Zhaoxia JING Jisong ZHU Rongxing HU | 2018 | Journal of Modern Power Systems and Clean Energy2018，6，4： | 6 |
| 18 | Mechanical assisted electroless barrel-plating Ni-P coatings on magnesium alloy显示文摘A mechanically assisted electroless barrel-plating Ni-P was carried out in a rolling drum containing Mg alloy specimens and ceramic balls, which was submerged in a bath containing electroless plating solution. It is demonstrated that the Ni-P coatings deposited by this novel technique have a crystallized Ni-P solid solution structure, showing fine-grains, higher hardness, and higher corrosion resistance compared with the conventional electroless plated amorphous Ni-P coatings. After heat treatment at 400 ℃ for 1 h, the structure of such Ni-P coatings were transformed to a structure with Ni-Ni3P double phases, and cracks in these coatings could not be observed, whereas cracks appeared seriously in the conventional electroless plated Ni-P coating after same heat treatment. Therefore, both hardness and corrosion resistance of these Ni-P coatings can be improved further by heat treatment. All of these beneficial effects can be attributed to the role of mechanical attrition during the mechanically assisted electroless barrel-plating process. | Zhaoxia PING Juntao YUAN Yedong HE Xiaogang LI | 2009 | Acta Metallurgica Sinica(English Letters)2009，22，3： | 6 |
| 19 | Progress on the application of electrochemiluminescence biosensor based on nanomaterials显示文摘Electrogenerated chemiluminescence, also known as electrochemiluminescence, abbreviated ECL, is a new technology combining electrochemistry and chemiluminescence. It is generated by high-energy electrons generated on the surface of the electrode in the emission process of excited state photons formed in the transfer process, and is a perfect combination of electrochemistry and spectroscopy. It not only has the advantages of good environment, high luminosity and wide dynamic range, but also has the characteristics of simple, stable and practical electrochemical methods, and nearly zero background signals. With the rapid development of nanomaterials, due to their unique electrical properties, large specific surface area, good biocompatibility and other characteristics, various nanomaterials have been widely used in the field of biosensors and sensitive detection. This review presented a general description of the research status of four different types of biosensors from the last decade years, summarized the application forms of nanomaterials in ECL biosensor, and outlines the building patterns and application example of the four main types of biosensors. | Zhaoxia Shi Gongke Li Yufei Hu | 2019 | Chinese Chemical Letters2019，30，9： | 6 |
| 20 | Audiological evaluation in Chinese patients with mitochondrial encephalomyopathies显示文摘 | Liu Yuhe Xue Junfang Zhao Danhua Chen Li Yuan Yun Wang Zhaoxia | 2014 | Chinese Medical Journal2014，，12： | 6 |
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