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| 1 | Experiments on mechanical properties of salt rocks under cyclic loading显示文摘The primary purpose of underground gas storages is to provide gas for seasonal consumptions or strategic reserve.The periodical operations of gas injection and extraction lead to cyclic loading on the walls and surrounding rocks of gas storages.To investigate the mechanical behaviors of different host rocks in bedded salt deposit,laboratory experiments were conducted on the samples of rock salt,thenardite,glauberite and gypsum.The mechanical properties of rock samples under monotonic and cyclic loadings were studied.Testing results show that,under monotonic loading,the uniaxial compressive stress(UCS) of glauberite is the largest(17.3 MPa),while that of rock salt is the smallest(14.0 MPa).The UCSs of thenardite and gypsum are 16.3 and 14.6 MPa,respectively.The maximum strain at the peak strength of rock salt(halite) is much greater than those of the other three rocks.The elastic moduli of halite,thenardite,glauberite and gypsum are 3.0,4.2,5.1 and 6.8 GPa,respectively.Under cyclic loading,the peak strengths of the rock specimens are deteriorated except for rock salt.The peak strengths of thenardite,glauberite and gypsum decrease by 33.7%,19.1% and 35.5%,respectively;and the strains of the three rocks at the peak strengths are almost the same.However,the strain of rock salt at the peak strength increases by 1.98%,twice more than that under monotonic loading.Under monotonic loading,deformation of the tested rock salt,thenardite and glauberite shows in an elastoplastic style.However,it changes to a ductile style under cyclic loading.Brittle deformation and failure are only observed for gypsum.The results should be helpful for engineering design and operation of gas storage in bedded salt deposit. | Weiguo Liang Chuanda Zhang Hongbo Gao Xiaoqin Yang Suguo Xu Yangsheng Zhao | 2012 | Journal of Rock Mechanics and Geotechnical Engineering2012，4，1： | 8 |
| 2 | Nonlinear Coupled Mathematical Model for Solid Deformation and Gas Seepage in Fractured Media显示文摘 | Yangsheng Zhao Yaoqing Hu Baohu Zhao Dong Yang | 2004 | Transport in Porous Media2004，，2： | 2 |
| 3 | The constitute law of gasseepage in rock fractures undergoing three-dimensional stress显示文摘 | Yang Dong Zhao Yangsheng Hu Yaoqing | 2006 | Transport in Porous Media2006，63，3： | 1 |
| 4 | The constitute law of gas seepage in rock fractures undergoing three-dimensional stress 显示文摘 | Yang Dong Zhao Yangsheng Hu Yaoqing | 2006 | Transport in Porous Media2006，63，3： | 1 |
| 5 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin promotes migration ability of primary cultured rat astrocytes via aryl hydrocarbon receptor显示文摘Emerging evidence showed that 2,3,7,8-Tetrachlorodibenzo-p-dioxin(TCDD) could induce expression of certain reactivation-associated genes in astrocytes, however, the consequent cellular effects and molecular mechanisms are still unclear. During the process of astrocyte reactivation, migration is a critical cellular event. In the present study, we employed woundhealing assay and Transwell? motility assay to explore the effects of TCDD on cell migration in primary cultured rat cortical astrocytes. We found that upon TCDD treatments at relative low concentrations(10^(-10) and/or 10^(-9) mol/L), the ability of primary astrocytes to migrate horizontally and vertically was promoted. In line with this cellular effect, the mR NA expression of two promigratory genes, including cell division cycle 42(CDC42) and matrix metalloproteinase 2(MMP2)was induced by TCDD treatment. Dioxin exerts its toxic effects mainly through aryl hydrocarbon receptor(AhR) pathway. So the role of AhR pathway in the pro-migratory effects of TCDD was examined using an AhR antagonist, CH223191. We found that application of CH223191 significantly reversed the pro-migratory effects of TCDD. Interestingly, the basal ability of horizontal migration as well as basal levels of CDC42 and MMP2 expression were dramatically reduced suggesting a possible physiological role of AhR in maintaining the endogenous migration ability of the primary astrocytes. These findings support the notion that dioxin promotes astrocyte reactivation at molecular and cellular levels. | Yangsheng Chen Rui Sha Li Xu Yingjie Xia Yiyun Liu Xuejun Li Heidi Qunhui Xie Naijun Tang Bin Zhao | 2019 | Journal of Environmental Sciences2019，31，2： | 1 |
| 6 | The constitute law of gas seepage in rock fractures undergoing three-dimensional stress显示文摘 | Yang Dong Zhao Yangsheng Hu Yaoqing | 2006 | Transport in Porous Media2006，63，3： | 1 |
| 7 | The experiment of gas adsorption and desorption under the action of high tempertature and high pressure water显示文摘 | Xie Jianlin Zhao Yangsheng Li Xiangchun | 2011 | Procedia Engineering2011，26，： | 1 |
| 8 | Numerical simulalion of the top coal caving process using the discrete element method 显示文摘 | Xie Yaoshe Zhao Yangsheng | 2009 | International Journal of Rock Mechanics and Mining Sciences2009，46，6： | 1 |
| 9 | Forecast and evaluation of hot dry roe geothermal resource in China 显示文摘 | ZHIJUN WAN YANGSHENG ZHAO JIANRONG KANG | 2005 | Renewable Energy2005，30，12： | 1 |
| 10 | Adaptive load observer-based feed-forward control in PMSM drive system显示文摘 | Zhao Shouhua Chen Yangsheng Mao Yongle | 2015 | Transactions of the Institute of Measure- ment and Control2015，37，3： | 1 |
| 11 | Experiments on methane displacement by carbon dioxide in large coal specimens 显示文摘 | Liang Weiguo Zhao Yangsheng Wu Di | 2011 | Rock Mechanics and Rock Engineering2011，44，5： | 1 |
| 12 | Experiments on methane displacement by carbon dioxide in large coal specimens显示文摘 | Liang Weiguo Zhao Yangsheng Wu Di | 2011 | RockMechanics and Rock Engineering2011，44，5： | 1 |
| 13 | The consti- tute law of gas seepage in rock fractures undergoing three-dimensional stress 显示文摘 | Yang Dong Zhao Yangsheng Hu Yaoqing | 2006 | Transport in Porous Media2006，63，3： | 1 |
| 14 | The constitute law of gas seepage in rock fractures undergoing three-dimensional stress 显示文摘 | Dong Yang Yangsheng Zhao Yaoqing Hu | 2006 | Transport in Porous Media2006，63，3： | 1 |
| 15 | Nonlinear coupled mathematical model for solid deformation and gas seepage in fractured media显示文摘 | Yangsheng Zhao Yaoqing Hu Baohu Zhao | 2004 | Transport in Porous Media2004，55，2： | 1 |
| 16 | The experiment of gas adsorption and desorption under the action of high temperature and high pressure water显示文摘 | Xie Jianlin Zhao Yangsheng Li Xiangchun | 2011 | Procedia Engineering2011，26，： | 1 |
| 17 | Laboratory experiment on coalbed methane desorption influenced by water injection and temperature显示文摘 | Zhao Dong Feng Zengchao Zhao Yangsheng | 2011 | Journal of Canadian Petroleum Technology2011，50，78： | 1 |
| 18 | Experi-mental investigation of the temperature and pore pressureeffect on permeability of lignite under the in situ condi-tion 显示文摘 | NIU Shiwei ZHAO Yangsheng HU Yaoqing | 2012 | Transport in Porous Media2012，101，1： | 1 |
| 19 | The experimental approach to effective stress law of coal mass by effect of methane显示文摘 | Zhao Yangsheng Hu Yaoqing Wei Jingping | 2003 | Transport in Porous Media2003，53，： | 1 |
| 20 | Identification of differentially expressed genes response to TCDD in rat brain after long-term low-dose exposure显示文摘Several cohort studies have reported that dioxin and dioxin-like polychlorinated biphenyls might impair the nervous system and lead to neurological or neurodegenerative diseases in the elder people, but there is limited research on the involved mechanism. By using microarray analysis, we figured out the differentially expressed genes between brain samples from SD rats after low-dose(0.1 μg/(kg?bw)) dioxin exposure for six months and controls. To investigate the function changes in the course of dioxin exposure, Gene Ontology(GO) annotation and Kyoto Encyclopedia of Genes and Genomes(KEGG) pathway analysis were performed on the differentially expressed genes. And the changes of several picked genes have been verified by real-time PCR. A total of 145 up-regulated and 64 down-regulated genes were identified. The metabolic processes, interleukin-1 secretion and production were significantly associated with the differentially expressed genes. And the genes regulated by dioxin also clustered to cholinergic synapse and long-term potentiation. Candidate biomarker genes such as egr1, gad2, gabrb3, abca1, ccr5 and pycard may be toxicological targets for dioxin. Furthermore, synaptic plasticity and neuro-immune system may be two principal affected areas by dioxin. | Yangsheng Chen Li Xu Heidi Q.H.Xie Tuan Xu Hualing Fu Songyan Zhang Rui Sha Yingjie Xia Bin Zhao | 2017 | Journal of Environmental Sciences2017，29，12： | 1 |
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