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| 1 | TRPV1 activation improves exercise endurance and energy metabolism through PGC-1α upregulation in mice显示文摘 | Zhidan Luo Liqun Ma Zhigang Zhao Hongbo He Dachun Yang Xiaoli Feng Shuangtao Ma Xiaoping Chen Tianqi Zhu Tingbing Cao Daoyan Liu Bernd Nilius Yu Huang Zhencheng Yan Zhiming Zhu | 2012 | Cell Research2012,22,3: | 18 |
| 2 | Down-regulation of microRNA-26b modulates non-small cell lung cancer cells chemoresistance and migration through the association of PTEN显示文摘在非小的房间肺癌症(NSCLC ) 探索 microRNA-26b (miR-26b ) 的效果房间,我们由量的反向的 transcriptase 聚合酶链反应与 NSCLC 从人的病人在 4 根 NSCLC 房间线和 10 件临床的样品调查了 miR-26b 的 mRNA 层次。miR-26b 在 NSCLC 房间和人的癌纸巾是显著地下面调整的,这被发现。合成 oligonucleotides 在 NSCLC 房间线 H1299 和 A549 房间习惯于起来调整或下面调整 miR-26b。结果证明下面调整、起来调整的 miR-26b 没在 H1299 或 A549 房间在癌症房间增长上有效果,而 miR-26b 在表示上增加了癌症房间移植并且减少了 cisplatin chemosensitivity。磷酸酶和 tensin 相当或相同的事物(PTEN ) 被证实由由双酶的记者试金的 miR-26b 直接固定,并且在 miR-26b 是下面调整的过去表示的 NSCLC 房间。最后,当 PTEN 在 NSCLC 房间是起来调整的时,它在 NSCLC 移植和 cisplatin chemosensitivity 上颠倒了 miR-2b 在表示上的效果。在结论,我们的数据在调整 NSCLC 显示出 miR-26b 的功能的机制。它显示 miR-26b 可以通过 PTEN 的规定调整 NSCLC 移植和 chemosensitivity。 | Naixin Liang Xiaoyun Zhou Ming Zhao Dachun Zhao Zhaohui Zhu Shanqing Li Huaxia Yang | 2015 | Acta Biochimica et Biophysica Sinica2015,47,7: | 4 |
| 3 | Use of N,O-carboxymethyl chitosan to prevent postsurgical adhesions in a rabbit double uterine horn model: a randomized controlled design显示文摘In previous studies, N,O-carboxymethyl chitosan has been shown to decrease the incidence and intensity of abdominal adhesions. In the present study, adhesions were induced in 220 rabbits using a double uterine horn model. Rabbits were randomized to receive an operation only or an operation+medical chitosan intraperitoneally. Twenty-two rabbits from each group were euthanized at one of five different times(Day 3, 7, 14, 28, or 42), and adhesion formation was given gross and histopathological scores. Reductions were observed in adhesion extent(P=0.0337) and tenacity(P=0.0271) as well as inflammation(P<0.0001) on Day 3 when medical chitosan was applied. Prior to Day 14, fibrosis was less obvious in the medical chitosan group(P<0.0005). The tenacity scores were significantly lower in the medical chitosan group following Day 14(P<0.05), while the type scores were lower in the medical chitosan group following Day 28(P<0.03). Thus, medical chitosan decreased both the gross and the histopathological scores of the induced adhesions. | Chang Ren Dachun Zhao Lan Zhu | 2016 | Science China(Life Sciences)2016,59,5: | 3 |
| 4 | Subwaveleng imaging with anisotropic structure comprising alternately layered metal and dieletric films 显示文摘 | WANG Changtao ZHAO Yanhui GAN Dachun | 2008 | Optics Express(S1094-4087)2008,16,6: | 1 |
| 5 | Large animal models of cardiac ischemia-reperfusion injury:Where are we now?显示文摘Large animal models of cardiac ischemia-reperfusion are critical for evaluation of the efficacy of cardioprotective interventions prior to clinical translation.Nonetheless,current cardioprotective strategies/interventions formulated in preclinical cardiovascular research are often limited to small animal models,which are not transferable or reproducible in large animal models due to different factors such as:(i)complex and varied features of human ischemic cardiac disease(ICD),which are challenging to mimic in animal models,(ii)significant differences in surgical techniques applied,and(iii)differences in cardiovascular anatomy and physiology between small versus large animals.This article highlights the advantages and disadvantages of different large animal models of preclinical cardiac ischemic reperfusion injury(IRI),as well as the different methods used to induce and assess IRI,and the obstacles faced in using large animals for translational research in the settings of cardiac IR. | Attaur Rahman Yuhao Li To-Kiu Chan Hui Zhao Yaozu Xiang Xing Chang Hao Zhou Dachun Xu Sang-Bing Ong | 2023 | Zoological Research2023,44,3: | 0 |
| 6 | 全国两会代表、委员谈标准显示文摘More than 5,000 of China’s political,business and social elite converged in Beijing in early March for the country’s most important annual meeting-the“Two Sessions”,which refers to the back-to-back meetings of two China’s major political bodies-the National People’s Congress(NPC)and Chinese People’s Political Consultative Conference(CPPCC). | Yang Zhen Deng Zhonghan Mai Jiaomeng Wang Yongtian Dong Mingzhu Ding Lei Lei Jun An Ting Zhang Tianren Ji Guifeng Liu Muhua Zhou Yunjie Zhao Yiwu Han Yongjin Guan Peijun Ni Minjing Zhao Dachun Lan Minbo | 2021 | China Standardization2021,,3: | 0 |
| 7 | Retraction:Down-regulation of microRNA-26b modulate non-small cell lung cancer cells chemoresistance and migration through the association of PTEN显示文摘Acta Biochim Biophys Sin,2015,530-538,Advance Access Publication:June 11,2015,http://gffzzd3cc09b8251d45dfsnvu0f0c0ou6960q6.ffgz.tsg.suse.edu.cn/10.1093/abbs/gmv046 Following a recent review of the data underlying this paper,which was conducted in cooperation with the original laboratory,the corresponding author and other colleagues determined the primer design for miR-26b in qPCR was inaccurate. | Naixin Liang Xiaoyun Zhou Ming Zhao Dachun Zhao Zhaohui Zhu Shanqing Li Huaxia Yang | 2021 | Acta Biochimica et Biophysica Sinica2021,53,12: | 0 |