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| 1 | Detection of cognitive impairment in patients with obstructive sleep apnea hypopnea syndrome using mismatch negativity显示文摘In this experiment,97 patients with obstructive sleep apnea hypopnea syndrome were divided into three groups(mild,moderate,severe) according to minimum oxygen saturation,and 35 healthy subjects were examined as controls.Cognitive function was determined using the mismatch negativity paradigm and the Montreal Cognitive Assessment.The results revealed that as the disease worsened,the mismatch negativity latency was gradually extended,and the amplitude gradually declined in patients with obstructive sleep apnea hypopnea syndrome.Importantly,mismatch negativity latency in severe patients with a persistent time of minimum oxygen saturation < 60 seconds was significantly shorter than that with a persistent time of minimum oxygen saturation > 60 seconds.Correlation analysis revealed a negative correlation between minimum oxygen saturation latency and Montreal Cognitive Assessment scores.These findings indicate that intermittent night-time hypoxemia affects mismatch negativity waveforms and Montreal Cognitive Assessment scores.As indicators for detecting the cognitive functional status of obstructive sleep apnea hypopnea syndrome patients,the sensitivity of mismatch negativity is 82.93%,the specificity is 73.33%,the accuracy rate is 81.52%,the positive predictive value is 85.00%,the negative predictive value is 70.21%,the positive likelihood ratio is 3,and the negative likelihood ratio is 0.23.These results indicate that mismatch negativity can be used as an effective tool for diagnosis of cognitive dysfunction in obstructive sleep apnea hypopnea syndrome patients. | Xiaohui Wen Ningyu Wang Jinfeng Liu Zhanfeng Yan Zhonghai Xin | 2012 | Neural Regeneration Research2012，7，20： | 6 |
| 2 | The interaction between grain boundary and tool geometry in nanocutting of a bi-crystal copper显示文摘Anisotropy is one central influencing factor on achievable ultimate machined surface integrity of metallic materials.Specifically,grain boundary has a strong impact on the deformation behaviour of polycrystalline materials and correlated material removal at the microscale.In the present work,we perform molecular dynamics simulations and experiments to elucidate the underlying grain boundaryassociated mechanisms and their correlations with machining results of a bi-crystal Cu under nanocutting using a Berkovich tool.Specifically,crystallographic orientations of simulated bi-crystal Cu with a misorientation angle of 44.1°are derived from electron backscatter diffraction characterization of utilized polycrystalline copper specimen.Simulation results reveal that blocking of dislocation motion at grain boundaries,absorption of dislocations by grain boundaries and dislocation nucleation from grain boundaries are operating deformation modes in nanocutting of the bi-crystal Cu.Furthermore,heterogeneous grain boundary-associated mechanisms in neighbouring grains lead to strong anisotropic machining behaviour in the vicinity of the grain boundary.Simulated machined surface morphology and machining force evolution in the vicinity of grain boundary qualitatively agree well with experimental results.It is also found that the geometry of Berkovich tool has a strong impact on grain boundary-associated mechanisms and resultant ploughing-induced surface pile-up phenomenon. | Zhanfeng Wang Tao Sun Haijun Zhang Guo Li Zengqiang Li Junjie Zhang Yongda Yan Alexander Hartmaier | 2019 | International Journal of Extreme Manufacturing2019，1，4： | 2 |
| 3 | Anisotropy-Related Machining Characteristics in Ultra-Precision Diamond Cutting of Crystalline Copper显示文摘Deformation behavior at grain levels greatly affects the machining characteristics of crystalline materials.In the present work,we investigate the influence of material anisotropy on ultra-precision diamond cutting of single crystalline and polycrystalline copper by experiments and crystal plasticity finite element simulations.Specifically,diamond turning and in situ SEM orthogonal cutting experiments are carried out to provide direct experimental evidence of the material anisotropy-dependent cutting results in terms of machined surface morphology and chip profile.Corresponding numerical simulations with the analysis of built stress further validate experimental results and reveal the mechanisms governing the material anisotropy influence.The above findings provide insight into the fabrication of ultra-smooth surfaces of polycrystalline metals by ultraprecision diamond turning. | Zhanfeng Wan Junjie Zhang Guo Li Zongwei Xu Haijun Zhang Jianguo Zhang Alexander Hartmaier Fengzhou Fang Yongda Yan Tao Sun | 2020 | Nanomanufacturing and Metrology2020，3，2： | 2 |
| 4 | Structural variation(SV)-based pan-genome and GWAS reveal the impacts of SVs on the speciation and diversification of allotetraploid cottons显示文摘Structural variations(SVs)have long been described as being involved in the origin,adaption,and domes-tication of species.However,the underlying genetic and genomic mechanisms are poorly understood.Here,we report a high-quality genome assembly of Gossypium barbadense acc.Tanguis,a landrace that is closely related to formation of extra-long-staple(ELS)cultivated cotton.An SV-based pan-genome(Pan-SV)was then constructed using a total of 182593 non-redundant SVs,including 2236 inversions,97398 insertions,and 82959 deletions from 11 assembled genomes of allopolyploid cotton.The utility of this Pan-sV was then demonstrated through population structure analysis and genome-wide association studies(GWASs).Using segregation mapping populations produced through crossing ELS cotton and the landrace along with an Sv-based GWAs,certain SVs responsible for speciation,domestication,and improvement in tetraploid cottons were identified.Importantly,some of the SVs presently identified as associated with the yield and fiber quality improvement had not been identified in previous SNP-based GWAS.In particular,a 9-bp insertion or deletion was found to associate with elimination of the interspecific reproductive isolation between Gossypium hirsutum and G.barbadense.Collectively,this study provides new insights into genome-wide,gene-scale SVs linked to important agronomic traits in a major crop spe-cies and highlights the importance of sVs during the speciation,domestication,and improvement of culti-vated crop species. | Shangkun Jin Zegang Han Yan Hu Zhanfeng Si Fan Dai Lu He Yu Cheng Yiqjan Li Ting Zhao Lei Fang Tianzhen Zhang | 2023 | Molecular Plant2023，16，4： | 1 |
| 5 | Influences of sample storage and grinding on the extraction of soil amino sugars显示文摘Soil amino sugars have been widely used to evaluate the potential roles of microbes in mediating soil carbon(C)cycling and various pretreatment methods were used for its extraction.However,few studies assessed their potential influences on the soil amino sugar extraction.In this study,we investigated the effects of sample storage method and grinding on amino sugar extraction across different climatic zones and land uses.Results showed that the concentrations of soil amino sugars varied greatly among sample pretreatments and their impacts were highly dependent on climatic condition and land use.Specifically,higher concentrations of amino sugars were extracted from field-moist samples than dried samples in subtropical grassland,temperate forest and arable land with no significant differences among storage methods for the samples from subtropical forest,arable land,and temperate grassland.Moreover,grinding improved the extraction efficiency of amino sugars for the dried soils.Due to the reduced extraction concentration in dried soils,field-moist samples were recommended in priority.For the dried soils used for the long-term storage,grinding can be an option to improve the extraction efficiency.Such information will be valuable for reducing the uncertainty and improving the accuracy during the determination of soil amino sugars. | Zhijian Mou Luhui Kuang Biyue Yan Xinyu Zhang Yunqiang Wang Zhanfeng Liu | 2020 | Soil Ecology Letters2020，2，2： | 1 |
| 6 | Rare earth elements,the magic industry vitamins——An interview with Dr.Yang Zhanfeng and Dr.Yan Huizhong显示文摘Rare earth arouses frequently international eyes in recent years.Public concern with rare earth and its usage.A TV reporter (hereinafter Reporter) interviewed two experts Prof.Yang Zhanfeng (hereinafter Yang),the deputy chief engineer of Baotou Iron&Steel Corporation (Group) and Prof.Yan Huizhong (hereinafter Yan),chief expert of Baotou Research Institute of Rare Earths.They introduced the current situation of Chinese rare earth industry. | Yang Zhanfeng Yan Huizhong | 2020 | China Rare Earth Information2020，26，2： | 0 |
| 7 | Genomic insights into the genetic basis of cotton breeding in China显示文摘The excellent Upland cotton(Gossypium hirsutum)cultivars developed since 1949 have made a huge contribution to cotton production in China,the world's largest producer and consumer of cotton.However,the genetic and genomic basis for the improvements of these cotton cultivars remains largely unclear.In this study,we selected 16 Upland cotton cultivars with important historical status in Chinese cotton breeding and constructed a multiparent,advanced generation,intercross(MAGiC)population comprising 920 recombinant inbred lines.A genome-wide association study using the MAGIC population identified 54 genomic loci associated with lint yield and fiber quality.Of them,25(46.30%)pleiotropic genomic loci cause simultaneous changes of lint yield and/or fiber quality traits,revealing complex trade-offs and linkage drags in Upland cotton agronomic traits.Deep sequencing data of 11 introduced ancestor cultivars and publicly available resequencing datasets of 839 cultivars developed in China during the past 70 years were integrated to explore the historical distribution and origin of the elite or selected alleles.Interestingly,85%oftheseelitealleles were selectedandfixed fromdifferent Americanancestors,consistentwithcotton breeding practices in China.However,seven elite alleles of native origin that are responsible for Fusarium wilt resistance,early maturing,good-quality fiber,and other characteristics were not found in American an-cestors but have greatly contributed to Chinese cotton breeding and wide cultivation.Taken together,these results provide a genetic basis for further improving cotton cultivars and reveal that the genetic composition of Chinese cotton cultivars is narrow and mainly derived from early introduced American varieties. | Yiqian Li Zhanfeng Si Guoping Wang Zhuolin Shi Jinwen Chen Guoan Qi Shangkun Jin Zegang Han Wenhao Gao Yue Tian Yun Mao Lei Fang Yan Hu Hong Chen Xiefei Zhu Tianzhen Zhang | 2023 | Molecular Plant2023，16，4： | 0 |
| 8 | A new model system for cotton indoor genetic and genomic research显示文摘Dear Editor,As an important fiber and oil crop,cotton has gradually developed into a model plant for studying fiber or seed trichome and polyploid evolution.Thus,strengthening cotton research is essential.Significant progress has been made in the research of cotton genomics(Hu et al.,2019;Huang and Zhu,2021;Wen et al.,2022).However,further research has been hindered due to its long growth period(usually 4–6 months per generation)and large plant size(usually 0.8–1.5 m in height). | Jun Zhang Zhanfeng Si Rui Chen Wangshu Liu Yue Shi Zhuolin Shi Huan Mei Yan Hu Lei Fang Tianzhen Zhang | 2023 | Science China(Life Sciences)2023，66，6： | 0 |
| 9 | Thermally activated flux flow,vortex-glass phase transition and the mixed-state Hall effect in 112-type iron pnictide superconductors显示文摘The transport properties in the mixed state of high-quality Ca_(0.8)La_(0.2)Fe_(0.98)Co_(0.02)As_2single crystal,a newly discovered 112-type iron pnictide superconductor,are comprehensively studied by magneto-resistivity measurement.The field-dependent activation energy,U_0,is derived in the framework of thermally activated flux flow(TAFF)theory,yielding a power law dependence U_0~H~αwith a crossover at a magnetic field around 2 T in both H⊥ab and H//ab,which is ascribed to the different pinning mechanisms.Moreover,we have clearly observed the vortex phase transition from vortex-glass to vortex-liquid according to the vortex-glass model,and vortex phase diagrams are constructed for both H⊥ab and H//ab.Finally,the results of mixed-state Hall effect show that no sign reversal of transverse resistivityρ_(xy)(H)is detected,indicating that the Hall component arising from the vortex flow is in theories or experiments previously reported on some high-T_ccuprates. | XiangZhuo Xing ZhanFeng Li XiaoLei Yi JiaJia Feng ChunQiang Xu Nan Zhou Yan Meng YuFeng Zhang YongQiang Pan LingYao Qin Wei Zhou HaiJun Zhao ZhiXiang Shi | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，12： | 0 |
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