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您的检索式：作者名="Yuqing Zong"
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| 1 | Bistratal Au@Bi2S3 nanobones for excellent NIR-triggered/multimodal imaging-guided synergistic therapy for liver cancer显示文摘To fabricate a highly biocompatible nanoplatform enabling synergistic therapy and real-time imaging,novel Au@Bi2S3 core shell nanobones(NBs)(Au@Bi2S3 NBs)with Au nanorods as cores were synthesized.The combination of Au nanorods with Bi2S3 film made the Au@Bi2S3 NBs exhibit ultrahigh photothermal(PT)conversion efficiency,remarkable photoacoustic(PA)imaging and high computed tomography(CT)performance;these Au@Bi2S3 NBs thus are a promising nanotheranostic agent for PT/PA/CT imaging.Subsequently,poly(N-vinylpyrrolidone)-modified Au@Bi2S3 NBs(Au@Bi2S3-PVP NBs)were successfully loaded with the anticancer drug doxorubicin(DOX),and a satisfactory pH sensitive release profile was achieved,thus revealing the great potential of Au@Bi2S3-PVP NBs in chemotherapy as a drug carrier to deliver DOX into cancer cells.Both in vitro and in vivo investigations demonstrated that the Au@Bi2S3-PVP NBs possessed multiple desired features for cancer therapy,including extremely low toxicity,good biocompatibility,high drug loading ability,precise tumor targeting and effective accumulation.Highly efficient ablation of the human liver cancer cell HepG2 was achieved through Au@Bi2S3-PVP NB-mediated photothermal therapy(PTT).As both a contrast enhancement probe and therapeutic agent,Au@Bi2S3-PVP NBs provided outstanding NIR-triggered multi-modal PT/PA/CT imaging-guided PTT and effectively inhibited the growth of HepG2 liver cancer cells via synergistic chemo/PT therapy. | Ruizhuo Ouyang Penghui Cao Pengpeng Jia Hui Wang Tianyu Zong Chenyu Dai Jie Yuan Yuhao Li Dong Sun Ning Guo Yuqing Miao Shuang Zhou | 2021 | Bioactive Materials2021，6，2： | 5 |
| 2 | Epidermal growth factor receptor is overexpressed in neuroblastoma tissues and cells显示文摘Neuroblastoma 是在童年的最普通的腹的恶意的肿瘤。指向肿瘤房间表面受体的 Immunotoxin (信息技术) 是一条新增补治疗学的处理途径。如果信息技术治疗能被用来对待倔强的 neuroblastoma,这研究的目的是在 neuroblastoma 房间线和纸巾检测表皮的生长因素受体(EGFR ) 的表示,并且探索。在人的 neuroblastoma 织物样品的 EGFR 表示被 immunohistochemistry 检测 ? 染色。EGFR 表示的积极的率在 neuroblastoma 织物是 81.0% 并且 50.0% 在 gangliocytoma,分别地,但是没有在他们之间的统计意义(P ?>? 0.05 ) 。分别地,在有利类型和相反的类型的 EGFR 表示的积极的率是 62.5% 和 92.3% ,但是他们不是统计上不同的(P ?>? 0.05 ) 。从化疗前和化疗以后的样品的结果证明没有重要统计差别(P ?>? 0.05 ) 在他们之间在 EGFR 表示。而且,在五根 neuroblastoma 房间线的 EGFR 表示层次用基于房间的 ELISA 试金和西方的污点分析被测量。结果证明 EGFR 的表示在 KP-N-NS 是更高的并且是(2 )-C 在另外的房间比那些排队。我们的结果表明有在 neuroblastoma 纸巾以及在 neuroblastoma 房间线的 EGFR 的一致、普遍的表情,建议开发由在 EGFR 指向的 neuroblastoma 的未来处理策略是可能的。 | Chao Zheng Ruling Shen Kai Li Na Zheng Yuqing Zong Danrong Ye Qingcheng Wang Zuopeng Wang Lian Chen Yangyang Ma | 2016 | Acta Biochimica et Biophysica Sinica2016，48，8： | 0 |
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