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| 1 | The Tartary Buckwheat Genome Provides Insights into Rutin Biosynthesis and Abiotic Stress Tolerance显示文摘 | Zhang, Lijun Li, Xiuxiu Ma, Bin Gao, Qiang Du, Huilong Han, Yuanhuai Li, Yan Cao, Yinghao Qi, Ming Zhu, Yaxin Lu, Hongwei Ma, Mingchuan Liu, Longlong Zhou, Jianping Nan, Chenghu Qin, Yongjun Wang, Jun Cui, Lin Liu, Huimin Liang, Chengzhi Qiao, Zhijun | 2017 | Molecular Plant2017，10，9： | 53 |
| 2 | Stenting for symptomatic intracranial arterial stenosis in China:1-year outcome of a multicentre registry study显示文摘background and purpose A multicentre prospective registry study of individually tailored stenting for a patient with symptomatic intracranial atherosclerotic stenosis(ICAS)combined with poor collaterals in China showed that the short-term safety and efficacy of stenting was acceptable.However,it remained uncertain whether the low event rate could be of a long term.We reported the 1-year outcome of this registry study to evaluate the long-term efficacy of individually tailored stenting for patients with severe symptomatic ICAS combined with poor collaterals.Methods Patients with symptomatic ICAS caused by 70%-99% stenosis located at the intracranial internal carotid,middle cerebral,intracranial vertebral or basilar arteries combined with poor collaterals were enrolled.Balloon-mounted stent or balloon plus self-expanding stent were selected based on the ease of vascular access and lesion morphology determined by the operators.The primary outcome was the rate of 30-day stroke,transient ischaemic attack and death,and 12-month ischaemic stroke within the same vascular territory,haemorrhagic stroke and vascular death after stenting.results From September 2013 to January 2015,300 patients(ages 58.3±9.78 years)were recruited.Among them,159 patients were treated with balloon-mounted stent and 141 with balloon plus self-expanding stent.During the 1-year follow-up,25 patients had a primary end point event.The probability of primary outcome at 1 year was 8.1%(95% CI 5.3% to 11.7%).In 76 patients with digital subtraction angiography follow-up,27.6%(21/76)had re-stenosis≥50% and 18.4%(14/76)had re-stenosis≥70%.No baseline characteristic was associated with the primary outcome.Conclusion The event rate remains low over 1 year of individually tailored stenting for patients with severe symptomatic ICAS combined with poor collaterals.Further randomised trial of comparing individually tailored stenting with best medical therapy is needed. | Ning Ma Yong Zhang Jie Shuai Changchun Jiang Qiyi Zhu Kangning Chen Li Liu Baomin Li Xiangqun Shi Lianbo Gao Yajie Liu Feng Wang Yongli Li Tieyan Liu Hongbo Zheng Dapeng Mo Feng Gao Yilong Wang Yongjun Wang Lei Feng Zhongrong Miao | 2018 | Stroke & Vascular Neurology2018，3，3： | 29 |
| 3 | Safety and efficacy of ciprofol vs.propofol for sedation in intensive care unit patients with mechanical ventilation:a multi-center,open label,randomized,phase 2 trial显示文摘Background:Ciprofol(HSK3486;Haisco Pharmaceutical Group Co.,Ltd.,Chengdu,China),developed as a novel 2,6-disubstituted phenol derivative showed similar tolerability and efficacy characteristics as propofol when applicated as continuous intravenous infusion for 12 h maintenance sedation in a previous phase 1 trial.The phase 2 trial was designed to investigate the safety,efficacy,and pharmacokinetic characteristics of ciprofol for sedation of patients undergoing mechanical ventilation.Methods:In this multicenter,open label,randomized,propofol positive-controlled,phase 2 trial,39 Chinese intensive care unit patients receiving mechanical ventilation were enrolled and randomly assigned to a ciprofol or propofol group in a 2:1 ratio.The ciprofol infusion was started with a loading infusion of 0.1-0.2 mg/kg for 0.5-5.0 min,followed by an initial maintenance infusion rate of 0.30 mg·kg^(-1)·h^(-1),which could be adjusted to an infusion rate of 0.06 to 0.80 mg·kg^(-1)·h^(-1),whereas for propofol the loading infusion dose was 0.5-1.0 mg/kg for 0.5-5.0 min,followed by an initial maintenance infusion rate of 1.50 mg·kg^(-1)·h^(-1),which could be adjusted to 0.30-4.00 mg·kg^(-1)·h^(-1)to achieve-2 to+1 Richmond Agitation-Sedation Scale sedation within 6-24 h of drug administration.Results:Of the 39 enrolled patients,36 completed the trial.The median(min,max)of the average time to sedation compliance values for ciprofol and propofol were 60.0(52.6,60.0)min and 60.0(55.2,60.0)min,with median difference of 0.00(95%confidence interval:0.00,0.00).In total,29(74.4%)patients comprising 18(69.2%)in the ciprofol and 11(84.6%)in the propofol group experienced 86 treatment emergent adverse events(TEAEs),the majority being of severity grade 1 or 2.Drug-and sedation-related TEAEs were hypotension(7.7%vs.23.1%,P=0.310)and sinus bradycardia(3.8%vs.7.7%,P=1.000)in the ciprofol and propofol groups,respectively.The plasma concentration-time curves for ciprofol and propofol were similar.Conclusions:ciprofol is comparable to propofol with good tolerance and efficacy for sedation of Chinese intensive care unit patients undergoing mechanical ventilation in the present study setting.Trial registration:ClinicalTrials.gov,NCT04147416. | Yongjun Liu Xiangyou Yu Duming Zhu Jun Zeng Qinhan Lin Bin Zang Chuanxi Chen Ning Liu Xiao Liu Wei Gao Xiangdong Guan | 2022 | Chinese Medical Journal2022，，9： | 19 |
| 4 | Accurate energy model for WSN node and its optimal design显示文摘With the development of CMOS and MEMS technologies, the implementation of a large number of wireless distributed micro-sensors that can be easily and rapidly deployed to form highly redundant, self-configuring, and ad hoc sensor networks. To facilitate ease of deployment, these sensors operate on battery for extended periods of time. A particular challenge in maintaining extended battery lifetime lies in achieving communications with low power. For better understanding of the design tradeoffs of wireless sensor network (WSN), a more accurate energy model for wireless sensor node is proposed, and an optimal design method of energy effcient wireless sensor node is described as well. Different from power models ever shown which assume the power cost of each component in WSN node is constant, the new one takes into account the energy dissipation of circuits in practical physical layer. It shows that there are some parameters, such as data rate, carrier frequency, bandwidth, Tsw, etc, which have a significant effect on the WSN node energy consumption per useful bit (EPUB). For a given quality specification, how energy consumption can be reduced by adjusting one or more of these parameters is shown. | Kan Baoqiang Cai Li Zhu Hongsong Xu Yongjun | 2008 | Journal of Systems Engineering and Electronics2008，19，3： | 16 |
| 5 | Research Progress on Heat Stress of Rice at Flowering Stage显示文摘Global warming has caused frequent occurrence of heat stress at the flowering stage of single-season rice in the Yangtze River region of China, which results in declines of spikelet fertility and yield in rice. Rice flowering stage is the most sensitive period to high temperatures, and therefore, the key for heat stress happening is the flowering stage coinciding with high temperature, which causes spikelet fertility decreasing in heat-sensitive varieties, and is the major factor for heat injury differences among various rice planting regions. With the development of rice breeding, temperature indexes for heat stress has been converted from daily maximum temperature of 35 oC to 38 oC with the stress duration of more than 3 d. During the flowering stage, anther dehiscence inhibition and low pollen shedding onto the stigma are two main reasons for spikelet fertility reduction under high temperatures. At panicle initiation stage, high temperatures aggravate spikelet degeneration, and destroy floral organ development. Various types of rice varieties coexist in production, and indica-japonica hybrid rice demonstrates the highest heat resistance in general, followed by indica and japonica rice varieties. In production, avoiding high temperature is the main strategy of preventing heat stress, and planting suitable cultivars and adjustment of sowing date are the most effective measures. Irrigation is an effective real-time cultivation measure to decline the canopy temperature during the rice flowering stage. We suggested that further study should be focused on exploring heat injury differences among different rice variety types, and innovating rice-planting methods according to planting system changes in rice planting regions with extreme heat stress. Meanwhile, high temperature monitor and warning systems should be improved to achieve optimal heat stress management efficiencies. | WANG Yaliang WANG Lei ZHOU Jianxia HU Shengbo CHEN Huizhe XIANG Jing ZHANG Yikai ZENG Yongjun SHI Qinghua ZHU Defeng ZHANG Yuping | 2019 | Rice science2019，26，1： | 13 |
| 6 | Big Data and Data Science:Opportunities and Challenges of iSchools显示文摘Due to the recent explosion of big data, our society has been rapidly going through digital transformation and entering a new world with numerous eye-opening developments. These new trends impact the society and future jobs, and thus student careers. At the heart of this digital transformation is data science, the discipline that makes sense of big data. With many rapidly emerging digital challenges ahead of us, this article discusses perspectives on iSchools' opportunities and suggestions in data science education. We argue that iSchools should empower their students with 'information computing' disciplines, which we define as the ability to solve problems and create values, information, and knowledge using tools in application domains. As specific approaches to enforcing information computing disciplines in data science education, we suggest the three foci of user-based, tool-based, and applicationbased. These three foci will serve to differentiate the data science education of iSchools from that of computer science or business schools. We present a layered Data Science Education Framework (DSEF) with building blocks that include the three pillars of data science (people, technology, and data), computational thinking, data-driven paradigms, and data science lifecycles. Data science courses built on the top of this framework should thus be executed with user-based, tool-based, and application-based approaches. This framework will help our students think about data science problems from the big picture perspective and foster appropriate problem-solving skills in conjunction with broad perspectives of data science lifecycles. We hope the DSEF discussed in this article will help fellow iSchools in their design of new data science curricula. | Il-Yeol Song Yongjun Zhu | 2017 | Journal of Data and Information Science2017，2，3： | 12 |
| 7 | The calcium-dependent kinase OsCPK24 functions in cold stress responses in rice显示文摘Calcium-dependent protein kinases(CPKs)are serine/threonine protein kinases that function in plant stress responses. Although CPKs are recognized as key messengers in signal transduction, the specific roles of CPKs and the molecular mechanisms underlying their activity remain largely unknown. Here, we characterized the function of Os CPK_(24), a cytosol-localized calciumdependent protein kinase in rice. Os CPK_(24) was universally and highly expressed in rice plants and was induced by cold treatment. Whereas Os CPK_(24) knockdown plants exhibited increased sensitivity to cold compared to wild type(WT), Os CPK_(24)-overexpressing plants exhibited increased cold tolerance. Plants overexpressing Os CPK_(24) exhibited increased accumulation of proline(an osmoprotectant) and glutathione(an antioxidant) and maintained a higher GSH/GSSG(reduced glutathione to oxidized glutathione) ratio during cold stress compared to WT. In addition to these effects in response to cold stress, we observed the kinase activity of Os CPK_(24) varied under different calcium concentrations. Further,Os CPK_(24) phosphorylated Os Grx_(10), a glutathionedependent thioltransferase, at rates modulated by changes in calcium concentration. Together, our results support the hypothesis that Os CPK_(24) functions as a positive regulator of cold stress tolerance in rice, a process mediated by calcium signaling and involving phosphorylation and the inhibition of Os Grx_(10) to sustain higher glutathione levels. | Yu Liu Chunjue Xu Yanfen Zhu Lina Zhang Taiyu Chen Fei Zhou Hao Chen Yongjun Lin | 2018 | Journal of Integrative Plant Biology2018，60，2： | 12 |
| 8 | Endovascular therapy for Acute ischemic Stroke Trial (EAST): study protocol for a prospective, multicentre control trial in China显示文摘Background and purpose:5 recent trials have shown the benefit of endovascular treatment for acute ischaemic stroke(AIS)due to large vessel occlusion of the anterior circulation.This study aims to evaluate the safety and efficacy of Solitaire thrombectomy in patients with moderate-to-severe stroke in the Chinese population,which has a high prevalence of intracranial atherosclerosis.Methods and analysis:This multicentre prospective control study will involve 17 stroke centres in China,and plans to recruit 150 patients in the intervention group,and 150 patients in the medical group,in which patients meet enrolment criteria but refuse intervention.Patients with AIS due to large vessel occlusion indicated for treatment with Solitaire stent retriever within 12 hours of symptom onset,and who meet the inclusion and exclusion criteria,will be enrolled in this study.The primary efficacy endpoint is functional independence as defined by a modified Rankin Scale(mRS)score≤2 at 90 days or by functional improvement as defined by mRS,using shift analysis.The procedural efficacy endpoint is arterial recanalisation of the occluded target vessel measured by a modified Thrombolysis in Cerebral Infarction(mTICI)score equal or superior to 2b right following the use of the study device.The primary safety endpoint is symptomatic intracranial haemorrhage(sICH)within 24±3 hours postprocedure.Ethics and dissemination:The protocol was approved by the Ethics Committee at the coordinating centre and by the local Institutional Review Board of each participating centre.Trial registration number:NCT02350283. | Zhongrong Miao Xiaochuan Huo Feng Gao Xiaoling Liao Chunjuan Wang Ya Peng Yibin Cao Shengli Chen Meng Zhang Changchun Jiang Xiaoxiang Peng Cunfeng Song Liping Wei Qiyi Zhu Zaiyu Guo Li Liu Hang Lin Hua Yang Wei Wu Hui Liang Anding Xu Kangning Chen Xingquan Zhao Yuesong Pan Hao Li Liping Liu Yilong Wang Yongjun Wang EAST investigators | 2016 | Stroke & Vascular Neurology2016，1，2： | 8 |
| 9 | Stochastic Dynamic Economic Dispatch of Wind-integrated Electricity and Natural Gas Systems Considering Security Risk Constraints显示文摘As the proportion of wind power generation increases in power systems,it is necessary to develop new ways for wind power accommodation and improve the existing power dispatch model.The power-to-gas technology,which offers a new approach to accommodate surplus wind power,is an excellent way to solve the former.Hence,this paper proposes to involve power-to-gas technology in the integrated electricity and natural gas systems(IEGSs).To solve the latter,on one hand,a new indicator,the scale factor of wind power integration,is introduced into the wind power stochastic model to better describe the uncertainty of grid-connected wind power;on the other hand,for quantizing and minimizing the impact of the uncertainties of wind power and system loads on system security,security risk constraints are established for the IEGS by the conditional value-at-risk method.By considering these two aspects,an MILP formulation of a security-risk based stochastic dynamic economic dispatch model for an IEGS is established,and GUROBI obtained from GAMS is used for the solution.Case studies are conducted on an IEGS consisting of a modified IEEE 39-bus system and the Belgium 20-node natural gas system to examine the effectiveness of the proposed dispatch model. | Zexing Chen Gelan Zhu Yongjun Zhang Tianyao Ji Ziwen Liu Xiaoming Lin Zexiang Cai | 2019 | CSEE Journal of Power and Energy Systems2019，5，3： | 8 |
| 10 | Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction显示文摘 | Xiao-E Jia Ke Ma Tao Xu Lei Gao Shuang Wu Cong Fu Wenjuan Zhang Zhizhang Wang Kaiyu Liu Mei Dong Changbin Jing Chunguang Ren Zhiwei Dong Yi Chen Yi Jin Qiuhua Huang Xing Chang Min Deng Li Li Lingfei Luo Jun Zhu Yongjun Dang Hung-Chun Chang Leonard I Zon Yi Zhou Saijuan Chen Weijun Pan | 2015 | Cell Research2015，25，8： | 8 |
| 11 | Regulation of transcriptionally active genes via the catalytically inactive Cas9 in C. elegans and D. rerio显示文摘 | Lijiang Long Hong Guo Di Yao Kai Xiong Yongjun Li Pengpeng Liu Zuoyan Zhu Dong Liu | 2015 | Cell Research2015，25，5： | 7 |
| 12 | Comparative Study of ROCK1 and ROCK2 in Hippocampal Spine Formation and Synaptic Function显示文摘Rho-associated kinases(ROCKs)are serinethreonine protein kinases that act downstream of small Rho GTPases to regulate the dynamics of the actin cytoskeleton.Two ROCK isoforms(ROCK1 and ROCK2)are expressed in the mammalian central nervous system.Although ROCK activity has been implicated in synapse formation,whether the distinct ROCK isoforms have different roles in synapse formation and function in vivo is not clear.Here,we used a genetic approach to address this long-standing question.Both Rock1^+/- and Rock2^+/- mice had impaired glutamatergic transmission,reduced spine density,and fewer excitatory synapses in hippocampal CA1 pyramidal neurons.In addition,both Rockl^+/- and Rock2^+/- mice showed deficits in long-term potentiation at hippocampal CA1 synapses and were impaired in spatial learning and memory based on the water maze and contextual fear conditioning tests.However,the spine morphology of CA1 pyramidal neurons was altered only in Rock2^+/- but not Rock1^+/- mice.In this study we compared the roles of ROCK1 and ROCK2 in synapse formation and function in vivo for the first time.Our results provide a better understanding of the functions of distinct ROCK isoforms in synapse formation and function. | Jinglan Yan Youcan Pan Xiaoyan Zheng Chuanan Zhu Yu Zhang Guoqi Shi Lin Yao Yongjun Chen Nenggui Xu | 2019 | Neuroscience Bulletin2019，35，4： | 7 |
| 13 | RIGID-PLASTIC MECHANICAL MODEL FOR THE FORGING METHOD WITH HORIZONTAL V-SHAPED ANVIL显示文摘以便减少机械性质的 anisotropy,为有水平塑造 V 的铁砧的前进方法的 therigid 塑料的机械模型被介绍。通过铁砧形状的变化,前进方法能控制含纤维的织物方向,到改进轴的 forgings 的机械性质的 anisotropy,认识到一致前进。因此,前进方法能克服常规前进方法生产的缺点。有水平塑造 V 的铁砧和金属变丑的过程的前进方法的 Themechanism 被分析。有试验性的学习的理论分析的协议验证有水平塑造 V 的铁砧罐头的前进方法有效地控制轴的 forgings 的机械性质的事实。 | LIU Zhubai NI Liyong LIU Guohui ZHANG Yongjun ZHU Wenbo | 2006 | Chinese Journal of Mechanical Engineering2006，19，2： | 6 |
| 14 | Umbilical cord-derived mesenchymal stem cells regulate thymic epithelial cell development and function in Foxn 1^-/- mice显示文摘 | Guangyang Liu Lihua Wang Tianxiang Pang Delin Zhu Yi Xu Hanyu Wang Xiuli Cong Yongjun Liu | 2014 | Cellular & Molecular Immunology2014，11，3： | 6 |
| 15 | Ni-P-Nanodiamond composite electroless plating显示文摘The effect of nanodiamond content in electrolyte and rotational speed of the stirrer on the deposition rate of coatings,the nanodiamond content in coatings,the microstructure and the micro-hardness of coatings were studied.A self-made pin-on-disk tribo-meter was employed to evaluate the wear resistance of prepared coatings.Results show that the thickness of composite coating decreases with the rotational speed,while the micro hardness of coating and the content of nanodiamond in coating increase with increasing its content in electrolyte.The wear resistance of the composite coating deposited in an electrolyte with 6 g/L nanodiamond increases by 50% in contrast with the pure Ni-P coating. | Yongwei ZHU Yongjun CHEN Changhong ZHU Xiangqian SHEN | 2010 | Acta Metallurgica Sinica(English Letters)2010，23，6： | 4 |
| 16 | Early–Middle Triassic Intrusions in Western Inner Mongolia, China: Implications for the Final Orogenic Evolution in Southwestern Xing-Meng Orogenic Belt显示文摘The end-Permian to Early–Middle Triassic magmatic rocks in Inner Mongolia can provide valuable insights into the relationships between the collisional processes and the magmatic responses during the final orogenic evolution of Xing-Meng orogenic belt(XMOB). This paper presents zircon U-Pb ages and Hf isotopes, whole rock geochemical and Sr-Nd-Pb isotopic data for the Early–Middle Triassic diabases and monzogranites from the Langshan area, southwestern XMOB. Our results suggest that the studied diabases and monzogranites were respectively formed during Early Triassic and Middle Triassic. The Early Triassic diabases are characterized by 'arc-like' geochemical signatures, including enrichment in Rb, U and K, and depletion in Nb, Ta, P and Ti. They have negative to weak positive εNd(t) values(-3.1 to +1.5) and relatively high initial ratios of 208 Pb/204 Pb(35.968–37.346), 207 Pb/204 Pb(15.448–15.508) and 206 Pb/204 Pb(16.280–17.492), indicating a subduction-metasomatized enriched lithospheric mantle source. Their low Ba/Rb(2.72–6.56), Ce/Y(0.97–1.39) and(Tb/Yb)N ratios(1.31–1.45) suggest that the parental magma was likely originated from low degree partial melting of the phlogopite-bearing lherzolite in a spinel-stability field. The Middle Triassic monzogranites show high Sr/Y ratios, low Mg O, Cr and Ni contents, high Zr/Sm ratios(40–64), negative zircon εHf(t) values(-25.8 to-8.8), as well as relatively flat heavy rare earth element patterns. They were likely derived from low degree partial melting of a moderately thickened ancient lower crust. The diabases and the slightly postdated high Sr/Y granites in this study represent the magmatic responses to the final orogenic evolution in the southwestern XMOB. Together with regional works, we propose that the slab break-off of the Paleo-Asian oceanic lithosphere following the terminal collision between the North China Craton and the South Mongolia terranes triggered asthenospheric upwelling, and the ongoing convergence further initiated moderately crustal thickening and uplift in the XMOB. | Min Liu Shaocong Lai Da Zhang Renzhi Zhu Jiangfeng Qin Yongjun Di | 2019 | Journal of Earth Science2019，30，5： | 4 |
| 17 | Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition)显示文摘Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. | Hui-Chuan Sun Jian Zhou Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan Yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 无 | 2022 | Hepatobiliary Surgery and Nutrition2022，11，2： | 4 |
| 18 | Inner Attitude Integration Algorithm Based on Fault Detection for Strapdown Inertial Attitude and Heading Reference System显示文摘This article proposes a new inner attitude integration algorithm to improve attitude accuracy of the strapdown inertial attitude and heading reference system(SIAHRS),which,by means of a Kalman filter,integrates the calculated attitude from the accelerometers in inertial measuring unit(IMU),called damping attitudes,with those from the conventional IMU.As vehicle's acceleration could produce damping attitude errors,the horizontal outputs from accelerometers are firstly used to judge the vehicle's motion so as to determine whether the damping attitudes could be reasonably applied.This article also analyzes the limitation of this approach.Furthermore,it suggests a residual chi-square test to judge the validity of damping attitude measurement in real time,and accordingly puts forward proper information fusion strategy.Finally,the effectiveness of the proposed algorithm is proved through the experiments on a real system in dynamic and static states. | Liu Jianye,Zhu Yanhua,Lai Jizhou,Yu Yongjun Navigation Research Center,Nanjing University of Aeronautics and Astronautics,Nanjing 210016,China | 2010 | Chinese Journal of Aeronautics2010，23，1： | 4 |
| 19 | RECOVERING RE FROM LEACHING LIQUOR OF RARE EARTH ORE BY EXTRACTION显示文摘RECOVERINGREFROMLEACHINGLIQUOROFRAREEARTHOREBYEXTRACTIONChiRu'an;XuJingming;HePeijiong;ZhuYongjun(InstituteofNuclearEnergyTec... | Chi Ru’an Xu Jingming He Peijiong Zhu Yongjun(Institute of Nuclear Energy Technolegy,Tsinghua University,Beijing 100084) | 1995 | 中国有色金属学会会刊:英文版1995，5，4： | 4 |
| 20 | Tranexamic acid for acute intracerebral haemorrhage growth based on imaging assessment (TRAIGE): a multicentre, randomised, placebo- controlled trial显示文摘Background Studies show tranexamic acid can reduce the risk of death and early neurological deterioration after intracranial haemorrhage.We aimed to assess whether tranexamic acid reduces haematoma expansion and improves outcome in intracerebral haemorrhage patients susceptible to haemorrhage expansion.Methods We did a prospective,double-blind,randomised,placebo-controlled trial at 10 stroke centres in China.Acute supratentorial intracerebral haemorrhage patients were eligible if they had indication of haemorrhage expansion on admission imaging(eg,spot sign,black hole sign or blend sign),and were treatable within 8 hours of symptom onset.Patients were randomly assigned(1:1)to receive either tranexamic acid or a matching placebo.The primary outcome was intracerebral haematoma growth(>33% relative or>6 mL absolute)at 24 hours.Clinical outcomes were assessed at 90 days.Results Of the 171 included patients,124(72.5%)were male,and the mean age was 55.9±11.6 years.89 patients received tranexamic acid and 82 received placebo.The primary outcome did not differ significantly between the groups:36(40.4%)patients in the tranexamic acid group and 34(41.5%)patients in the placebo group had intracranial haemorrhage growth(OR 0.96,95% CI 0.52 to 1.77,p=0.89).The proportion of death was lower in the tranexamic acid treatment group than placebo group(8.1%vs 10.0%),but there were no significant differences in secondary outcomes including absolute intracranial haemorrhage growth,death and dependency.Conclusions Among patients susceptible to haemorrhage expansion treated within 8 hours of stroke onset,tranexamic acid did not significantly prevent intracerebral haemorrhage growth.Larger studies are needed to assess safety and efficacy of tranexamic acid in intracerebral haemorrhage patients. | Jingyi Liu Ximing Nie Hongqiu Gu Qi Zhou Haixin Sun Ying Tan Dacheng Liu Lina Zheng Jiahui Zhao Yan Wang Yibin Cao Haomeng Zhu Yunpeng Zhang Lijin Yi Yuehua Pu Miao Wen Zhonghua Yang Shengjun Sun Wenzhi Wang Xingquan Zhao Liping Liu Yongjun Wang | 2021 | Stroke & Vascular Neurology2021，6，2： | 3 |
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