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| 1 | Role and effect of vein-transplanted human umbilical cord mesenchymal stem cells in the repair of diabetic foot ulcers in rats显示文摘Diabetic foot ulcer(DFU)is one of diabetic complications,which is frequently present and tormented in diabetes mellitus.Most multipotent mesenchymal stromal cells(MSCs)are capable of immune evasion,providing an allogeneic,ready-to-use,cell product option for therapeutic applications.The beneficial effect of MSCs for the treatment of a variety of traumatic injuries,such as open wounds,has been extensively explored.In this study,a rat DFU model was used to simulate the pathophysiology of clinical patients and to investigate the localization of human umbilical cord mesenchymal stem cells(hUC-MSCs)after intravenous transplantation and its role in DFU healing,so as to evaluate the potential of hUC-MSCs in the treatment of DFU.The diabetic rat model was established by streptozotocin injection,which was used to create full-thickness foot dorsal skin wounds to mimic DFU by a 6-mm skin biopsy punch and a Westcott scissor.The hUC-MSCs were transplanted through femoral vein,and the ulcer cicatrization situation and the fate of hUC-MSCs were evaluated.Our data suggest that intravenously transplantated hUC-MSCs have the ability to migrate and locate to the wound tissue and are helpful to wound healing in DFU rats,partly by regulating inflammation,trans-differentiation and providing growth factors that promote angiogenesis,cell proliferation and collagen deposition.Herein,we demonstrate that hUC-MSC transplantation is able to accelerate DFU healing in rats and transplantation of exogenous stem cells may be a potential strategy for clinical application in DFUs. | Rongfeng Shi Weishuai Lian Yinpeng Jin Chuanwu Cao Shilong Han Xiaohu Yang Suming Zhao Maoquan Li Hui Zhao | 2020 | Acta Biochimica et Biophysica Sinica2020，52，6： | 13 |
| 2 | Regulation of phenylpropanoid biosynthesis by MdMYB88 and MdMYB124 contributes to pathogen and drought resistance in apple显示文摘MdMYB88 and MdMYB124 have been demonstrated to be responsible for lignin accumulation in apple under drought stress.In this study,using a metabolomic approach,we identified differentially accumulated phenylpropanoid and flavonoid metabolites in MdMYB88/124 transgenic RNAi plants under control and long-term drought stress conditions in apple roots.We confirmed the regulation of phenylalanine by MdMYB88 and MdMYB124 via UPLC-MS in apple roots under both control and drought conditions.Using Electrophoretic Mobility Shift Assay(EMSA)and ChIPquantitative PCR(qPCR)analyses,we found that MdMYB88 positively regulates the MdCM2 gene,which is responsible for phenylalanine biosynthesis,through binding to its promoter region.Under long-term drought conditions,MdMYB88/124 RNAi plants consistently accumulated increased amounts of H2O2 and MDA,while MdMYB88 and MdMYB124 overexpression plants accumulated decreased amounts of H2O2 and MDA.We also examined the accumulation of metabolites in the phenylpropanoid biosynthesis pathway in the leaves of MdMYB88 and MdMYB124 transgenic apple plants after long-term drought stress.We found that metabolites responsible for plant defense,including phenylpropanoids and flavonoids,accumulated less in the RNAi plants but more in the overexpression plants under both control and drought conditions.We further demonstrated that MdMYB88/124 RNAi plants were more sensitive to Alternaria alternata f.sp.mali and Valsa mali,two pathogens that currently severely threaten apple production.In contrast,MdMYB88 and MdMYB124 overexpression plants were more tolerant to these pathogens.The cumulative results of this study provided evidence for secondary metabolite regulation by MdMYB88 and MdMYB124,further explained the molecular roles of MdMYB88 and MdMYB124 in drought resistance,and provided information concerning molecular aspects of their roles in disease resistance. | Dali Geng Xiaoxia Shen Yinpeng Xie Yusen Yang Ruiling Bian Yuqi Gao Pengmin Li Liying Sun Hao Feng Fengwang Ma Qingmei Guan | 2020 | Horticulture Research2020，7，1： | 5 |
| 3 | Regulatory effect of salicylic acid and methyl jasmonate supplementation on ergosterol production in Hericium erinaceus mycelia显示文摘We evaluated the biomass and ergosterol content of Hericium erinaceus mycelium, and extracellular enzyme activities in H. erinaceus liquid culture following salicylic acid(SA) and methyl jasmonic acid(Me JA)supplementation. The optimal SA concentration was100 lmoláL-1, where the highest ergosterol content of 2.33 mgág-1was obtained following 6-day cultivation with100 lmoláL-1SA supplementation, and which was significantly higher than the unsupplemented control(p \ 0.01). Following 4-day supplementation with50 lmoláL-1Me JA, the highest ergosterol content obtained was 1.988 mgág-1, which was 25.8 % higher than the unsupplemented control. Our data indicate that SA and Me JA supplementation improves ergosterol content in H.erinaceus mycelium. | Xiaodong Dai Yaguang Zhan Jiechi Zhang Piqi Zhang Zenghua Han Qingfang Ma Xianghui Kong Jianing Liu Yinpeng Ma | 2015 | Journal of Forestry Research2015，26，1： | 5 |
| 4 | Apple SERRATE negatively mediates drought resistance by regulating MdMYB88 and MdMYB124 and microRNA biogenesis显示文摘The function of serrate(SE)in miRNA biogenesis in Arabidopsis is well elucidated,whereas its role in plant drought resistance is largely unknown.In this study,we report that MdSE acts as a negative regulator of apple(Malus×domestica)drought resistance by regulating the expression levels of MdMYB88 and MdMYB124 and miRNAs,including mdm-miR156,mdm-miR166,mdm-miR172,mdm-miR319,and mdm-miR399.MdSE interacts with MdMYB88 and MdMYB124,two positive regulators of apple drought resistance.MdSE decreases the transcript and protein levels of MdMYB88 and MdMYB124,which directly regulate the expression of MdNCED3,a key enzyme in abscisic acid(ABA)biosynthesis.Furthermore,MdSE is enriched in the same region of the MdNECD3 promoter where MdMYB88/MdMYB124 binds.Consistently,MdSE RNAi transgenic plants are more sensitive to ABA-induced stomatal closure,whereas MdSE OE plants are less sensitive.In addition,under drought stress,MdSE is responsible for the biogenesis of mdm-miR399,a negative regulator of drought resistance,and negatively regulates miRNAs,including mdm-miR156,mdm-miR166,mdm-miR172,and mdm-miR319,which are positive regulators of drought resistance.Taken together,by revealing the negative role of MdSE,our results broaden our understanding of the apple drought response and provide a candidate gene for apple drought improvement through molecular breeding. | Xuewei Li Pengxiang Chen Yinpeng Xie Yan Yan Liping Wang Huan Dang Jing Zhang Lingfei Xu Fengwang Ma Qingmei Guan | 2020 | Horticulture Research2020，7，1： | 4 |
| 5 | Heat transfer enhancement in the tube fitted with Left–Right helical blade rotors显示文摘 | Zhen Zhang Hua Yan Weimin Yang Yinpeng Zhou Yumei Ding Changfeng Guan | 2013 | Applied Thermal Engineering (-)2013，，1： | 4 |
| 6 | Genome-wide identification of droughtresponsive microRNAs in two sets of Malus from interspecific hybrid progenies显示文摘Drought stress can negatively impact apple fruit quality and yield.Apple microRNAs(miRNAs)participate in apple tree and fruit development,as well as in biotic stress tolerance;however,it is largely unknown whether these molecules are involved in the drought response.To identify drought-responsive miRNAs in Malus,we first examined the drought stress tolerance of ten F1 progenies of R3(M.×domestica)×M.sieversii.We performed Illumina sequencing on pooled total RNA from both drought-tolerant and drought-sensitive plants.The sequencing results identified a total of 206 known miRNAs and 253 candidate novel miRNAs from drought-tolerant plants and drought-sensitive plants under control or drought conditions.We identified 67 miRNAs that were differentially expressed in drought-tolerant plants compared with drought-sensitive plants under drought conditions.Under drought stress,61 and 35 miRNAs were differentially expressed in drought-tolerant and drought-sensitive plants,respectively.We determined the expression levels of seven out of eight miRNAs by stem-loop qPCR analysis.We also predicted the target genes of all differentially expressed miRNAs and identified the expression of some genes.Gene Ontology analyses indicated that the target genes were mainly involved in stimulus response and cellular and metabolic processes.Finally,we confirmed roles of two miRNAs in apple response to mannitol.Our results reveal candidate miRNAs and their associated mRNAs that could be targeted for improving drought tolerance in Malus species,thus providing a foundation for understanding the molecular networks involved in the response of apple trees to drought stress. | Chundong Niu Haiyan Li Lijuan Jiang Mingjia Yan Cuiying Li Dali Geng Yinpeng Xie Yan Yan Xiaoxia Shen Pengxiang Chen Jun Dong Fengwang Ma Qingmei Guan | 2019 | Horticulture Research2019，6，1： | 2 |
| 7 | Survivable Routing Protocol for Green Wireless Mesh Networks Based on Energy Efficiency显示文摘This paper proposes a new Energyefficient Survivable Routing Protocol(ESRP)based on solar energy and wind mixed for power supply in green wireless mesh networks(WMNs).The ESRP combines hop penalty strategy and flooding delaying strategy to improve the performances of traditional routing protocol.This paper uses QualNet to simulate and verify the performances of proposed ESRP.Compared with the traditional routing protocol,the simulation results show that the energy utilization of ESRP is more efficient by 13%.At the same time,ESRP is more load-balanced to postpone the appearance of the first energy depletion node and reduce the number of energy depletion nodes,and thus it effectively improves network survivability. | YU Yinpeng PENG Yuhuai LIU Yejun GUO Lei SONG Meng | 2014 | China Communications2014，11，8： | 1 |
| 8 | A dynam- ic decision network framework for online media adaptation in stroke rehabilitation显示文摘 | Chen Yinpeng Xu Weiwei Sundaram Hari | 2008 | ACM Transactions on Multime- dia Computing Communications and Applications2008，5，1： | 1 |
| 9 | Synthesis and charge/discharge properties of ferrocene-containing polytriphenylamine derivative as the cathode of lithium ion battery显示文摘 | Su Chang Ye Yinpeng Xu Lihuan | 2012 | Journal of Materials Chemistry2012，22，22： | 1 |
| 10 | Connection availability based protection algorithm in wireless-optical broadband access network显示文摘The hybrid Wireless-Optical Broadband Access Network(WOBAN)provides a new and promising architecture for broadband access network by combining the beneficial properties of wireless and optical access technologies.To avoid huge data loss,WOBAN needs to be designed with a high availability guarantee.The purpose of this paper is to protect the Passive Optical Network at the back-end using the backup radios in Wireless Mesh Network at the front-end.The proposed protection scheme is based on a connection availability model.First,we assigned several backup Optical Network Units(ONUs)for each primary ONU not satisfying the availability requirement of primary optical connection.Under the availability requirement of backup optical connection,each backup ONU needed to reserve the residual capacity as the backup capacity to fully protect the traffic demand of its primary ONU.Then,we selectively deployed the additional radio interfaces as the backup radios for the wireless routers in the front-end under the availability requirement of backup wireless connection,in order to establish the wireless-backup-path between each pair of primary and backup ONUs.Each backup radio on the wireless-backup-path will retain the backup radio capacity for rerouting traffic,so as to decrease the possibility of traffic block in case of failure.We aimed to design efficient heuristic algorithms and yield suboptimal solutions for minimizing the consumption of backup ONU capacity and the cost of backup radios.Simulation results demonstrate the advantage of the proposed scheme compared to previous works. | LIU YeJun GUO Lei YU YinPeng LI Bing XIANG Peng DAI CuiQin | 2014 | Science China(Information Sciences)2014，57，4： | 1 |
| 11 | Climate change and drought: a risk assessment of crop-yield impacts显示文摘 | Li Yinpeng Ye Wei Wang Meng | 2009 | Climate Research Clim Res2009，，6： | 1 |
| 12 | 4Zr alloy processed by ECAP 显示文摘 | Yinpeng Zhou Dejiang Li Xiaoqin Zeng The effect ofparticles on microstructure and mechanical behaviour ofMg-10Gd-3Y-0 | 2013 | MaterialsScience Forum2013，2530，44： | 1 |
| 13 | A new dynamic hierarchical reputation evaluation scheme for hybrid wireless mesh networks显示文摘 | Yao Yu Yuhuai Peng Yinpeng Yu Tianyu Rao | 2014 | Computers and Electrical Engineering2014，，2： | 1 |
| 14 | Experimental study on the effect of hydrodynamic conditions on flocculation and settling properties of fine-grain sediment显示文摘The flocculation of cohesive sediment particles is a function of the collision efficiency of sediment particles,which is mainly influenced by local flow hydrodynamics.A detailed study on local hydrodynamic characteristics in a novel stirred tank was done to measure the flow field of a turbulent flow.Instantaneous flow velocity fields were obtained and processed,and the average flow field was computed.Particle image velocimetry(PIV)results measuring the hydrodynamic characteristics(expressed as turbulent kinetic energy(TKE),local dissipation rate of TKE,velocity gradient or shear rate,turbulent shear stress,etc.)were analyzed and discussed.Particle tracking and automated image processing techniques were utilized to analyze the impact of the hydrodynamic conditions on the floc and settling properties.The differences in floc properties under the two turbulent shear states(i.e.,steady-state(SS)and unsteady-state(US))hydrodynamic conditions were examined.The results show that floc size and floc size distribution(FSD)of pure kaolin clay flocs are significantly influenced by the local dissipation rate of TKE and the turbulent intensity states.The floc size,df,84,at local dissipation rate of TKE of 11×10^(-4),29×10^(-4),44×10^(-4),83×10^(-4),and 142×10^(-4)m^(2)/s^(3)is 97,108,107,124,and 150 mm,respectively.It was found that by increasing the local dissipation rate of TKE,the FSD was skewed left.The US shear condition generated larger flocs(and in higher proportions)relative to the SS condition.The settling velocity and flux settling velocities of flocs formed under SS conditions are higher than those formed under US conditions.The fractal dimension of SS flocs also is higher than the fractal dimension of US flocs.These results highlight a significant impact of the states of hydrodynamics on floc properties such as floc size and FSD as well as the settling and morphological properties of flocs. | Bismark Odum Chunyang Xu Yongping Chen Yinpeng Yao Yan Zhou | 2023 | International Journal of Sediment Research2023，38，6： | 0 |
| 15 | Optimal Configuration of an Off-Grid Hybrid Wind-Hydrogen Energy System: Comparison of Two Systems显示文摘Due to the uncertainty of renewable energy power generation and the non-linearity of load demand,it becomes complicated to determine the capacity of each device in hybrid renewable energy power generation systems.This work aims to optimize the capacity of two types of the off-grid hybrid wind-hydrogen energy system.We considered the maximum profit of the system and the minimum loss of power supply probability as optimization goals.Firstly,we established steady-state models of the wind turbine,alkaline electrolyzer,lead-acid battery,and proton exchange membrane fuel cell in matrix laboratory software to optimize the capacity.Secondly,we analyzed the operating mode of the system and determined two system structures(system contains batteries whether or not).Finally,according to the wind speed and load in the sample area,we compared the economics of the two systems and selected the optimal configuration for the area.In the same calculation example data,the non-dominated sorting genetic algorithm-II(NSGA-II)is used to optimize the capacity of each device in the two systems.The results showed that the profit of the without battery-equipped system is 32.38%higher than another system.But the power supply reliability is the opposite.To avoid the contingency of the calculation results,we used the traditional genetic algorithm(GA)and ant colony optimization(ACO)to calculate the same example.The results showed that NSGA-II is significantly better than GA and ACO in terms of iteration steps and calculation results.The required architecture for the System-I composes of 3 numbers of 10 kW wind turbines,61 sets of 12 V·240 Ah leadacid batteries,8 kW electrolytic cell,and 6 kW PEMFC.The net profit and LPSP are ¥44,315 and 0.01254 respectively.The required architecture for the System-II composes of 2 numbers of 10 kW wind turbines,24 kW electrolytic cells,and 18 kW PEMFC.Net profit and LPSP are ¥58,663 and 0.03244,respectively.This paper provided two schemes for the optimal configuration of the hybrid wind-hydrogen energy system in islanding mode,which provided a theoretical basis for practical engineering applications. | Zekun Wang Yan Jia Yingjian Yang Chang Cai Yinpeng Chen | 2021 | Energy Engineering2021，118，6： | 0 |
| 16 | A New Species of Cyrtodactylus(Squamata:Gekkonidae)from the Karst Forests of Daweishan National Nature Reserve,Yunnan,China显示文摘Cyrtodactylus geckos are one of the most speciose and diverse groups of extant lizards known,distributed throughout the Asian and Pacific realms.Using molecular phylogenetic methods and supporting morphological data,we describe a new species of Cyrtodactylus in Daweishan National Nature Reserve,Yunnan Province,China.Cyrtodactylus hekouensis sp.nov.can be morphologically distinguished from its nearby congeners by the following characters:maximum SVL 92.3 mm and TL 98.5 mm;11-12 supralabials;11-12 infralabials;36-57 scale rows between the fifth supralabials;10-13 dorsal tubercles rows;3 postnasals on blunt and smooth front snout;precloacalfemoral pores in a continuous series of 33-39(females with pitted scales)located under vent/cloaca and thighs in both sexes;precloacal groove absent;3/3 postcloacal tubercles;subdigital lamellae under the fourth finger 21 or 22,under the fourth toe 20-23;smooth midbody with smooth venter and tuberculate dorsal scale rows,tubercles from head to tail base;dorsal transverse patterns are generally large,bilaterally symmetrical.The results of the phylogenetic analysis recover specimens of this new species as sister to a clade containing C.wayakonei and C.martini.Uncorrected pairwise intraspecific distances were<1%,and distances between our new species and other Cyrtodactylus species from nearby countries ranged from 14.2%to 26.8%. | YINPENG ZHANG XIAOLONG LIU JUSTIN BERNSTEIN Jian WANG Zhiyong YUAN | 2021 | Asian Herpetological Research2021，12，3： | 0 |
| 17 | Adipose-derived stem cells show hepatic differentiation potential and therapeutic effect in rats with acute liver failure显示文摘Hepatocyte transplantation contributes to the repair of liver damage,but hepatocyte resources are limited,making it difficult for this to become a routine treatment.Previous studies have confirmed that mesenchymal stem cells(MSCs)can be induced to differentiate into hepatocyte-like cells(HLCs)by adding different cytokine combinations in vitro,and they then play some roles of hepatocytes.Our previous studies found that the differentiation ability of stem cells is closely related to the origin of the tissue.To identify the mesenchymal stem cells that are most suitable for hepatic differentiation and the treatment of liver failure,we use a three-phase induction process in which human adipose-derived stem cells(hADSCs)and umbilical cord mesenchymal stem cells(hUCMSCs)are induced to differentiate towards HLCs in vitro,and rats with acute liver failure(ALF)induced by D-gal are cured by MSCs and MSC-derived HLCs(MSCs-HLC),respectively.We find that hADSCs are stronger than hUCMSCs in hepatic differentiation ability,and they have a better curative effect when using hADSCs-HLC or jointly using hADSCs and hADSCs-HLC,which has positive significance for hepatocyte regeneration,recovery of liver function and reduction of systemic inflammatory reaction,finally improving the survival rate of rats with acute liver failure. | Yinpeng Jin Rongfeng Shi Tangkai Qi Qiang Li Cong Chen Shane Gao Fengjuan Gao Danjing Yang Guangxi Sun Jianqing Xu Qingchun Fu Jun Xu Xiaoyan Zhang | 2023 | Acta Biochimica et Biophysica Sinica2023，55，4： | 0 |
| 18 | Analysis of Drill Pipe's Effect on Casing显示文摘 | Wang Changjin Li Lei Li Yinpeng Ha Mingda | 2015 | International English Education Research2015，，1： | 0 |
| 19 | A New Cyrtodactylus Species(Reptila:Gekkonidae)from Nan Province,Northern Thailand显示文摘Here,a new species of bent-toed gecko,Cyrtodactylus phukhaensis sp.nov.,is described from Doi Phu Kha,Nan province,Thailand based on molecular and morphological evidence.A phylogeny based on NADH dehydrogenase subunit 2(ND2)and its flanking tRNAs places the new species in the chauquangensis group as a sister taxon to Cyrtodact ylus wayakonei.The new species can be differentiated from other members of the chauquangensis group by having a unique combina tion of 7 or 8 suprala bials,23-28 longitudinal rows of dorsal tubercles,8-10 infrala bials,9 femoral pores,7 precloacal pores,40-47 ventral scales,and a lack of bands crossingthe temporal area.In addition,results from a chromosome study of C.phukhaensis sp.nov.showed that the new species has a diploid chromosome number of 40 with a fundamental number of 46.The formula of the karyotype was as follows:2n(40)=2m+4sm+34t.Our findings suggest that further studies of Cyrtodactylus biodiversity in northern Thailand are needed. | Siriwadee CHOMDEJ Waranee PRADIT Parinya PAWANGKHANANT Chakkrapong KUENSAEN Apichaya PHUPANBAI Mali NAIDUANGCHAN Promporn PIBOON Korakot NGANVONGPANIT Zhiyong YUAN Yinpeng ZHANG Jing CHE Phuping SUCHARITAKUL Chatmongkon SUWANNAPOOM | 2022 | Asian Herpetological Research2022，13，2： | 0 |
| 20 | Traditional Sports of Minority Nationalities Bloom显示文摘The Sixth National Games for Traditional Sports of Minority Nationalities opened at Beijing Workers' Stadium in September 1999. | ZHANG PING, CHENG WEIDONG and HUANG YINPENG | 2000 | Women of China2000，，1： | 0 |
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