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6篇 您的检索式:作者名="Yingan Liu"
    题名 作者 年代 出处 被引量
1Surface modelling of human population distribution in China显示文摘Yue Tianxiang Wang Yingan Liu Jiyuan 2005Ecological Modelling2005,181,4:1
2MSPD scenarios of spatial distribution of human population in China 显示文摘Yue Tianxiang Wang Yingan Liu Jiyuan 2005Population and Environment2005,26,3:1
3Surface modeling of human population distribution in China 显示文摘Yue Tianxiang Wang Yingan Liu jiyuan 2005Ecological Modelling2005,181,4:1
4Dirichlet process and its developments: a survey显示文摘The core of the nonparametric/semiparametric Bayesian analysis is to relax the particular parametric assumptions on the distributions of interest to be unknown and random,and assign them a prior.Selecting a suitable prior therefore is especially critical in the nonparametric Bayesian fitting.As the distribution of distribution,Dirichlet process(DP)is the most appreciated nonparametric prior due to its nice theoretical proprieties,modeling flexibility and computational feasibility.In this paper,we review and summarize some developments of DP during the past decades.Our focus is mainly concentrated upon its theoretical properties,various extensions,statistical modeling and applications to the latent variable models.Yemao XIA Yingan LIU Jianwei GOU 2022Frontiers of Mathematics in China2022,17,1:0
5IGF2-NR4A2 Signaling Regulates Macrophage Subtypes to Attenuate Liver Cirrhosis显示文摘Background and Aims:Liver cirrhosis can lead to liver failure and eventually death.Macrophages are the main contributors to cirrhosis and have a bidirectional role in regulating matrix deposition and degradation.Macrophage-based cell therapy has been developed as an alternative to liver transplantation.However,there is insufficient evidence regarding its safety and efficacy.In this study,we aimed to explore the effect of combining insulin-like growth factor 2(IGF2)with bone marrow-derived macrophages(BMDMs)to treat mice with liver cirrhosis.Methods:We assessed liver inflammation,fibrosis regression,liver function,and liver regeneration in mice with CCl4-induced cirrhosis and treated with BMDM only or IGF2+BMDM.We performed in vitro experiments in which activated hepatic stellate cells(HSCs)were co-cultured with macrophages in the presence or absence of IGF2.The polarity of macrophages and the degree of inhibition of HSCs were examined.The effect of IGF2 on macrophages was also verified by the overexpression of IGF2.Results:Combining IGF2 with BMDM reduced liver inflammation and fibrosis and increased hepatocyte proliferation.Combining IGF2 with BMDM was more effective than using BMDM alone.In vitro experiments demonstrated that IGF2 inhibited HSCs activation by upregulating NR4A2 to promote the anti-inflammatory macrophages phenotype.IGF2 also increased the synthesis of matrix metalloproteinases(MMPs)by macrophages,which may explain why administering IGF2 combined with BMDM was more effective than administering BMDM only.Conclusions:Our study provides a theoretical basis for the future use of BMDM-based cell therapy to treat liver cirrhosis.Lichao Yao Xue Hu Mengqin Yuan Qiuling Zhang Pingji Liu Lian Yang Kai Dai Yingan Jiang 2023Journal of Clinical and Translational Hepatology2023,11,4:0
6Developing, testing and application of rodent population dynamics and capture models based on an adjusted Leslie matrix-based population approach显示文摘Liyong Fu Shouzheng Tang Yingan Liu Ram P. Sharma Huiru Zhang Yuancai Lei Hong Wang Xinyu Song 2014International Journal of Biomathematics2014,7,3:0
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