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| 1 | Li intercalation in an MoSe_(2) electrocatalyst:In situ observation and modulation of its precisely controllable phase engineering for a high-performance flexible Li-S battery显示文摘Sophisticated efficient electrocatalysts are essential to rectifying the shuttle effect and realizing the high performance of flexible lithium-sulfur batteries(LSBs).Phase transformation of MoSe_(2) from the 2H phase to the 1T phase has been proven to be a significant method to improve the catalytic activity.However,precisely controllable phase engineering of MoSe_(2) has rarely been reported.Herein,by in situ Li ions intercalation in MoSe_(2),a precisely controllable phase evolution from 2H-MoSe_(2) to 1T-MoSe_(2) was realized.More importantly,the definite functional relationship between cut-off voltage and phase structure was first identified for phase engineering through in situ observation and modulation methods.The sulfur host(CNFs/1T-MoSe_(2))presents high charge density,strong polysulfides adsorption,and catalytic kinetics.Moreover,Li-S cells based on it display capacity retention of 875.3mAh g^(-1) after 500 cycles at 1 C and an areal capacity of 8.71mAh cm^(-2) even at a high sulfur loading of 8.47mg cm^(-2).Furthermore,the flexible pouch cell exhibiting decent performance will endow a promising potential in the wearable energy storage field.This study proposes an effective strategy to precisely control the phase structure of MoSe_(2),which may provide the reference to fabricate the highly efficient electrocatalysts for LSBs and other energy systems. | Yunke Wang Yige Zhao Kangli Liu Shaobin Wang Neng Li Guosheng Shao Feng Wang Peng Zhang | 2023 | Carbon Energy2023，5，2： | 2 |
| 2 | State Feedback Control for a Class of Fractional Order Nonlinear Systems显示文摘Using the Lyapunov function method,this paper investigates the design of state feedback stabilization controllers for fractional order nonlinear systems in triangular form,and presents a number of new results.First,some new properties of Caputo fractional derivative are presented,and a sufficient condition of asymptotical stability for fractional order nonlinear systems is obtained based on the new properties.Then,by introducing appropriate transformations of coordinates,the problem of controller design is converted into the problem of finding some parameters,which can be certainly obtained by solving the Lyapunov equation and relevant matrix inequalities.Finally,based on the Lyapunov function method,state feedback stabilization controllers making the closed-loop system asymptotically stable are explicitly constructed.A simulation example is given to demonstrate the effectiveness of the proposed design procedure. | Yige Zhao Yuzhen Wang Haitao Li | 2016 | IEEE/CAA Journal of Automatica Sinica2016，3，4： | 2 |
| 3 | Positive solutions for boundary value problems of nonlinear fractional differential equations显示文摘 | Yige Zhao Shurong Sun Zhenlai Han Meng Zhang | 2011 | Applied Mathematics and Computation2011，，16： | 1 |
| 4 | Positive solutions for boundary value problems of nonlinear fractional differential equations 显示文摘 | ZHAO Yige SUN Shurong HAN Zhenlai | 2011 | Applied Mathematics and Computation2011，217，16： | 1 |
| 5 | Oscillation for a class of fractional differential equation 显示文摘 | Han Zhenlai Zhao Yige Sun Ying | 2013 | Discrete Dynamics in Nature and Society2013，39，0282： | 1 |
| 6 | Direct-writing Process and in vivo Evaluation of Prevascularized Composite Constructs for Muscle Tissue Engineering Application显示文摘Tissue engineered skeletal muscle is expected to treat muscle defects caused by trauma and disease.However,designing and manufacturing thick and complex tissue engineered skeletal muscle requires vascularization to ensure its internal cell viability and nutrient supply in vitro.In this article,we developed a set of Direct-Writing(DW)bio-printing procedure to manufacture a prevascularized composite construct with Human Umbilical Vein Endothelial Cell(HUVEC)and C2C12 cells for muscle tissue engineering application.We put the cells into the construct during the DW process to obtain the prevascularization and intend to promote its vascularization in vivo later.The constructs with cells or without cells were implanted respectively into nude mice back for 3 weeks,after which the mice healthily live for all the time and all the implants are tightly bonded to the host.From immunohistochemical analysis,CD31-positive blood vessels existed in the implanted samples with cells are more substantial than those without cells,but the implanted samples with HUVEC and C2C12 cells have much more number of small blood vessels distributing evenly.Moreover,the implants with cells,especially that with HUVEC and C2C12 cells,are able to get better fusion with the host skin and subcutaneous tissues.Histological analysis demonstrates that our DW-based constructs have the potential to be getting to vascularize the tissue engineered muscle. | Qin Lian Tingze Zhao Tian Jiao Yige Huyan Heng Gu Lin Gao | 2020 | Journal of Bionic Engineering2020，17，3： | 1 |
| 7 | The existence of multiple positive solutions for boundary-value problems of nonlinear fractional differential equations显示文摘 | Zhao Yige Sun Shurong Han Zhenlai | 2011 | Commun Nonlinear Sci Numer Simulat2011，16，： | 1 |
| 8 | Sulfur Vacancy-Promoted Highly Selective Electrosynthesis of Functionalized Aminoarenes via Transfer Hydrogenation of Nitroarenes with H_(2)O over a Co_(3)S_(4−x) Nanosheet Cathode显示文摘Developing a selective hydrogenation strategy over a low-cost electrocatalyst,especially with an inexpensive and safe hydrogen source for efficient synthesis of aminoareneswith fragile functional groups,is extremely desirable.Herein,using H_(2)O as the hydrogen source,Ti mesh-supported Co_(3)S_(4)ultrathin nanosheets with sulfur vacancies(denoted as Co_(3)S_(4−x)NS)have been demonstrated to be a highly efficient cathode for selective transfer hydrogenation of nitroarenes to corresponding aminoarenes at low potential.D_(2)O-labeling experiments confirmed the hydrogen origin.Without sulfur vacancies,the products were a mixture of aminoarenes and azoxyareneswith lowselectivity.This method can deliver a variety of aminoarenes with outstanding selectivity and excellent functional group compatibility with highly reducible groups(e.g.,C–I,C–Br,C=O,C=C,C=N,C≡N,and C≡C).The experimental and theoretical results have revealed that sulfur vacancies can enhance the selective specific adsorption of the nitro group and promote intrinsic activity to form active hydrogen from water electrolysis,thus resulting in high selectivity and outstanding fragile functional groups tolerance. | Yige Zhao Cuibo Liu Changhong Wang Xiaodan Chong Bin Zhang | 2021 | CCS Chemistry2021，3，1： | 1 |
| 9 | Uniqueness of positive solutions for boundary value problems of singular fractional differential equations显示文摘 | SUN Shurong ZHAO Yige HAN Zhenlai XU Meirong | 2012 | Inverse Problems in Science and Engineering2012，20，3： | 1 |
| 10 | The existence of multiple positive solutions for boundary value problems of nonlinear fractionol differential equations显示文摘 | Yige Zhao Shurong Sun Zhenlai Han | 2011 | Commun Nonlinear Sci Numer Simulat2011，16，： | 1 |
| 11 | Positive solutions for for a coupled system of nonlinear differential equations of mixed fractional orders显示文摘 | ZHAO Yige SUN Shurong HAN Zhenlai | 2011 | Advance in difference Equations2011，2011，1： | 1 |
| 12 | Theexistence of multiple positive solutions for boundary value problems of nonlinear fractional differential equations显示文摘 | Zhao Yige Sun Shurong Han Zhenlai | 2011 | Commun Nonlinear Sci Numer Simulat2011，，16： | 1 |
| 13 | The existence of solutions for boundary value problems of fractional hybrid differential equations显示文摘 | Sun Shurong Zhao Yige Han Zhenlai | 2012 | Communications in Nonlinear Science and Numerical Simulation2012，17，12： | 1 |
| 14 | Positive solutions for for a coupled system of nonlinear differential equations of mixed fractional orders显示文摘 | Zhao Yige Sun Shurong Han Zhenlai | 2011 | Advance in Difference Equa- tions2011，，： | 1 |
| 15 | Positive solutions for boundary value problems of nonlinear fractional differential equations显示文摘 | Zhao Yige Sun Shurong Hart Zhenlai | 2011 | Applied Mathematics and Computation2011，，217： | 1 |
| 16 | The existence of multiple positive solutions for boundary value problems of nonlinear fractional differential equations显示文摘 | Zhao Yige Sun Shurong Han Zhenlai | | 0，，04： | 1 |
| 17 | Positive solutions for boundary value problems of nonlinear fractional differential equations显示文摘 | Zhao Yige Sun Shurong Han Zhenlai | 2011 | Applied Mathematics and Computation2011，，217： | 1 |
| 18 | Will Coal Price Fluctuations Affect Renewable Energy Substitution and Carbon Emission? A Computable General Equilibrium-Based Study of China显示文摘Changes in the energy price system will determine the direction of evolution of the energy industry structure.As a country where coal is the dominant energy source,what is the effect of coal price fluctuations on China’s industry development costs and energy consumption structure?To investigate this problem,this paper utilized an economy–energy–environment computable general equilibrium model.In this study,four aspects were analyzed:Energy supply side,proportion of renewable energy consumption,macroeconomy,and changes in CO_(2) emissions.The results of this study show that an increase of 10%–20%in coal prices contributes to a shift into using renewable energy,which leads to energy saving and emission reduction.Renewable energy and clean energy rose by 0.57%–4.47%in the energy structure,but this has a certain negative impact on the macroeconomy.The gross domestic product(GDP)fell by 0.07%–0.18%.As a result,the decline in coal prices became an obstacle to renewable energy substitution and energy conservation.In addition,we put forward policy suggestions according to the results in energy,economic,and environmental effects. | Wenhui Zhao Yibo Yin Lu Mao Konglu Zhong Guanghui Yuan Hai Huang Yige Yang | 2021 | Energy Engineering2021，118，4： | 0 |
| 19 | Performance Comparison of Computational Methods for the Prediction of the Function and Pathogenicity of Non-coding Variants显示文摘Non-coding variants in the human genome significantly influence human traits and complex diseases via their regulation and modification effects.Hence,an increasing number of computational methods are developed to predict the effects of variants in human non-coding sequences.However,it is difficult for inexperienced users to select appropriate computational methods from dozens of available methods.To solve this issue,we assessed 12 performance metrics of 24 methods on four independent non-coding variant benchmark datasets:(1)rare germline variants from clinical relevant sequence variants(ClinVar),(2)rare somatic variants from Catalogue Of Somatic Mutations In Cancer(COSMIC),(3)common regulatory variants from curated expression quantitative trait locus(eQTL)data,and(4)disease-associated common variants from curated genomewide association studies(GWAS).All 24 tested methods performed differently under various conditions,indicating varying strengths and weaknesses under different scenarios.Importantly,the performance of existing methods was acceptable for rare germline variants from ClinVar with the area under the receiver operating characteristic curve(AUROC)of 0.4481–0.8033 and poor for rare somatic variants from COSMIC(AUROC=0.4984–0.7131),common regulatory variants from curated eQTL data(AUROC=0.4837–0.6472),and disease-associated common variants from curated GWAS(AUROC=0.4766–0.5188).We also compared the prediction performance of 24 methods for non-coding de novo mutations in autism spectrum disorder,and found that the combined annotation-dependent depletion(CADD)and context-dependent tolerance score(CDTS)methods showed better performance.Summarily,we assessed the performance of 24 computational methods under diverse scenarios,providing preliminary advice for proper tool selection and guiding the development of new techniques in interpreting non-coding variants. | Zheng Wang Guihu Zhao Bin Li Zhenghuan Fang Qian Chen Xiaomeng Wang Tengfei Luo Yijing Wang Qiao Zhou Kuokuo Li Lu Xia Yi Zhang Xun Zhou Hongxu Pan Yuwen Zhao Yige Wang Lin Wang Jifeng Guo Beisha Tang Kun Xia Jinchen Li | 2023 | Genomics, Proteomics & Bioinformatics2023，21，3： | 0 |
| 20 | GCH1 variants contribute to the risk and earlier age-at-onset of Parkinson's disease:a two-cohort case-control study显示文摘Background:Common and rare variants of guanosine triphosphate cyclohydrolase 1(GCH1)gene may play important roles in Parkinson's disease(PD).However,there is a lack of comprehensive analysis of GCH1 genotypes,especially in non-coding regions.The aim of this study was to explore the genetic characteristics of GCH1,including rare and common variants in coding and non-coding regions,in a large population of PD patients in Chinese mainland,as well as the phenotypic characteristics of GCH1 variant carriers.Methods:In the first cohort of this case-control study,we performed whole-exome sequencing in 1555 patients with early-onset or familial PD and 2234 healthy controls;then in the second cohort,whole-genome sequencing was performed in sporadic late-onset PD samples(1962 patients),as well as 1279 controls.Variants at target GCH1 regions were extracted,and then genetic and detailed phenotypic data were analyzed using regression models and the sequence kernel association test.We also performed a meta-analysis to correlate deleterious GCH1 variants with age at onset(AAO)in PD patients.Results:For coding variants,we identified a significant burden of GCH1 deleterious variants in early-onset or familial PD cases compared to controls(1.2%VS 0.1%,P<0.0001).In the analysis of possible regulatory variants in GCH1 non-coding regions,rs12323905(P=0.001,odds ratio=1.19,95%CI 1.07-1.32)was significantly associated with PD,and variant sets in untranslated regions and intron regions,GCH1 brain-specific expression quantitative trait loci,and two possible promoter/enhancer(GH14J054857 and GH14J054880)were suggestively associated with PD.Genotype phenotype correlation analysis revealed that the carriers of GCH1 deleterious variants manifested younger AAO(P<0.0001),and had milder motor symptoms,milder fatigue symptoms and more autonomic nervous dysfunctions.Meta-analysis of six studies demonstrated 6.4-year earlier onset in GCH1 deleterious variant carriers(P=0.0009).Conclusions:The results highlight the importance of deleterious variants and non-coding variants of GCH1 in PD in Chinese mainland and suggest that GCH1 mutation can influence the PD phenotype,which may help design experimental studies to elucidate the mechanisms of GCH1 in the pathogenesis of PD. | Hong-xu Pan Yu-wen Zhao Jun-pu Mei Zheng-huan Fang Yige Wang Xun Zhou Yang-jie Zhou Rui Zhang Kai-lin Zhang Li Jiang Qian Zeng Yan He Zheng Wang Zhen-hua Liu Qian Xu Qi-ying Sun Yang Yang Ya-cen Hu Ya-se Chen Juan Du Li-fang Lei Hai-nan Zhang Chun-yu Wang Xin-xiang Yan Lu Shen Hong Jiang Jie-qiong Tan Jin-chen Li Bei-sha Tang Ji-feng Guo | 2020 | Translational Neurodegeneration2020，9，3： | 0 |
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