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| 1 | Unsupervised content-preserving transformation for optical microscopy显示文摘The development of deep learning and open access to a substantial collection of imaging data together provide a potential solution for computational image transformation,which is gradually changing the landscape of optical imaging and biomedical research.However,current implementations of deep learning usually operate in a supervised manner,and their reliance on laborious and error-prone data annotation procedures remains a barrier to more general applicability.Here,we propose an unsupervised image transformation to facilitate the utilization of deep learning for optical microscopy,even in some cases in which supervised models cannot be applied.Through the introduction of a saliency constraint,the unsupervised model,named Unsupervised content-preserving Transformation for Optical Microscopy(UTOM);can learn the mapping between two image domains without requiring paired training data while avoiding distortions of the image content.UTOM shows promising performance in a wide range of biomedical image transformation tasks,including in silico histological staining,fluorescence image restoration,and virtual fluorescence labeling.Quantitative evaluations reveal that UTOM achieves stable and high-fidelity image transformations across different imaging conditions and modalities.We anticipate that our framework will encourage a paradigm shift in training neural networks and enable more applications of artificial intelligence in biomedical imaging. | Xinyang Li Guoxun Zhang Hui Qiao Feng Bao Yue Deng Jiamin Wu Yangfan He Jingping Yun Xing Lin Hao Xie Haoqian Wang Qionghai Dai | 2021 | Light(Science & Applications)2021，10，3： | 1 |
| 2 | Graphene/Semiconductor Heterostructure Wireless Energy Harvester through Hot Electron Excitation显示文摘Recharging the batteries by wireless energy facilitates the long-term running of the batteries,which will save numerous works of battery maintenance and replacement.Thus,harvesting energy form radio frequency(RF)waves has become the most promising solution for providing the micropower needed for wireless sensor applications,especially in a widely distributed 4G/5G wireless network.However,the current research on rectenna is mainly focused on the integrated antenna coupled with metal-insulator-metal tunneling diodes.Herein,by adopting the plasmon excitation of graphene and quantum tunneling process between graphene and GaAs or GaN,we demonstrated the feasibility of harvesting energy from the 915MHz wireless source belonging to 5G in the FR1 range(450MHz-6 GHz)which is also known as sub-6G.The generated current and voltage can be observed continuously,with the direction defined by the built-in field between graphene and GaAs and the incident electromagnetic waves treated as the quantum energy source.Under the RF illumination,the generated current increases rapidly and the value can reach in the order of 10^(-8)-10^(-7)A.The harvester can work under the multiple channel mode,harvesting energy simultaneously from different flows of wireless energy in the air.This research will open a new avenue for wireless harvesting by using the ultrafast process of quantum tunneling and unique physical properties of graphene. | Yangfan Xuan Hong Chen Yan Chen Haonan Zheng Yanghua Lu Shisheng Lin | 2020 | Research2020，，1： | 1 |
| 3 | In-situ construction of high-mechanical-strength and fast-ion-conductivity interphase for anode-free Li battery显示文摘The solid electrolyte interphase(SEI)with strong mechanical strength and high ion conductivity is highly desired for Li metal batteries,especially for harsh anode-free batteries.Herein,we report a pragmatic approach to the in-situ construction of high-quality SEI by applying synergistic additives of Li NO_(3)and ethylene sulfite(ES)in the electrolyte.The obtained SEI exhibits a high average Young’s modulus(9.02GPa)and exchanging current density(4.59 mA cm^(-2)),which are 3.0 and 1.2 times as large as those using the sole additive of LiNO_(3),respectively.With this improved SEI,Li-dendrite growth and side reactions are effectively suppressed,leading to an ultra-high Coulombic efficiency(CE)of 99.7%for Li plating and stripping.When applying this improved electrolyte in full cells,it achieves a high capacity retention of 89.7%for over 150 cycles in a LiFePO_(4)||Li battery(~12 mg cm^(-2)cathode,50μm Li)and of 44.5%over 100 cycles in a LiFePO_(4)||Cu anode-free battery. | Yangfan Lin Juner Chen Han Zhang Jianhui Wang | 2023 | Journal of Energy Chemistry2023，，5： | 1 |
| 4 | Lateral variation in seismic velocities and rheology beneath the Qinling-Dabie orogen显示文摘The Qinling-Dabie orogen is an important tectonic belt that trends east-west and divides continental China into northern and southern parts.Due to its strong deformation,complicated structure,multiphase structural superposition and the massive exposed high and ultrahigh metamorphic rocks,its tectonic formation and geodynamical evolution are hot research topics worldwide.Previous studies mainly focused on the regional geological or geochemical aspects,whereas the geophysical constraints are few and isolated,in particular on the orogenic scale.Here,we integrate the available P- and S-wave seismic and seismicity data,and construct the rheological structures along the Qinling-Dabie orogen.The results demonstrate that:(1)there are strong lateral variations in the crustal velocity between the western and eastern sections of the Qinling-Dabie orogen,indicating the different origin and tectonic evolution between these two parts;(2) the lateral variations are also manifested in the rheological structure.The rigid blocks,such as South China and Ordos basin(North China Craton),resist deformation and show low seismicity.The weak regions,such as the margin of Tibet and western Qinling-Dabie experience strong deformation and accumulated stress,thus show active seismicity;(3) in the lower crust of most of the HP/UHP terranes the values of P-wave velocity are higher than the global average ones;finally(4) low P- and S-wave velocities and low strength in the lower crust and lithospheric mantle beneath Dabie indicate lithospheric delamination,and/or high temperature,and partial melting condition. | DENG YangFan CHEN Lin XU Tao WU Jing Fabio ROMANELLI Giuliano Francesco PANZA | 2017 | Science China Earth Sciences2017，60，3： | 1 |
| 5 | Temperature effect on the electrical, structural and optical properties of N-doped ZnO films by plasma-free metal organic chemical vapor deposition显示文摘 | Ying Zhu Shisheng Lin Yinzhu Zhang Zhizhen Ye Yangfan Lu Jianguo Lu Binghui Zhao | 2009 | Applied Surface Science2009，，12： | 1 |
| 6 | Shear Behavior of Open Steel Tube Connectors in Steel⁃UHPC Composite Decks显示文摘Steel and ultra⁃high performance concrete(UHPC)composite decks are effective at reducing fatigue cracking and asphalt pavement damage.The shear behavior of innovative open steel tube(OST)connectors in steel⁃UHPC composite decks was investigated by conducting push⁃out tests.The test parameter is the presence of reinforcement in the deck.The load⁃slip curves and shear behavior of the push⁃out specimens were obtained and discussed.The test results indicate that as compared with plain concrete specimens,the limit slip of reinforced specimens decreased by 32%and the shear stiffness increased by 10%,but the ultimate shear capacity was almost the same.The use of UHPC influenced the failure process as it was observed that the OST connector was sheared off at its lower semi⁃tube,followed by the pull⁃out failure of the upper semi⁃tube.A finite element model was verified by tests and was then used to analyze the deformation and failure behaviors of the composite deck with open tubes.The model demonstrates that there is a stress concentration zone at the connector root,and the lower semi⁃tube is the main component that is subject to loads. | Lin Ye Wenping Cai Yangfan Zhuang Yang Du Qiu Zhao | 2021 | Journal of Harbin Institute of Technology(New Series)2021，28，5： | 0 |
| 7 | Mechanotransduction pathways in articular chondrocytes and the emerging role of estrogen receptor-α显示文摘In the synovial joint,mechanical force creates an important signal that influences chondrocyte behavior.The conversion of mechanical signals into biochemical cues relies on different elements in mechanotransduction pathways and culminates in changes in chondrocyte phenotype and extracellular matrix composition/structure.Recently,several mechanosensors,the first responders to mechanical force,have been discovered.However,we still have limited knowledge about the downstream molecules that enact alterations in the gene expression profile during mechanotransduction signaling.Recently,estrogen receptorα(ERα)has been shown to modulate the chondrocyte response to mechanical loading through a ligand-independent mechanism,in line with previous research showing that ERαexerts important mechanotransduction effects on other cell types,such as osteoblasts.In consideration of these recent discoveries,the goal of this review is to position ERαinto the mechanotransduction pathways known to date.Specifically,we first summarize our most recent understanding of the mechanotransduction pathways in chondrocytes on the basis of three categories of actors,namely mechanosensors,mechanotransducers,and mechanoimpactors.Then,the specific roles played by ERαin mediating the chondrocyte response to mechanical loading are discussed,and the potential interactions of ERαwith other molecules in mechanotransduction pathways are explored.Finally,we propose several future research directions that may advance our understanding of the roles played by ERαin mediating biomechanical cues under physiological and pathological conditions. | Ning Wang Yangfan Lu Benjamin B.Rothrauff Aojie Zheng Alexander Lamb Youzhen Yan Katelyn E.Lipa Guanghua Lei Hang Lin | 2023 | Bone Research2023，11，2： | 0 |
| 8 | Shock Initiation Experiments with Modeling on a DNAN Based MeltCast Insensitive Explosive显示文摘2,4-dinitroanisole(DNAN)is a good replacement for 2,4,6-trinitrotoluene(TNT)in melt-cast explosives due to its superior insensitivity.With the increasing use of DNAN-based melt-cast explosives,the prediction of reaction violence and hazard assessment of the explosives subjected to shock is of great significance.This study investigated the shock initiation characteristics for a DNAN-based melt-cast explosive,DHFA,using the one-dimensional Lagrangian apparatus.The embedded manganin gauges in the apparatus record the pressure histories at four Lagrangian positions and show that shock-todetonation transition in DHFA needs a high input shock pressure.The experimental data are analyzed to calibrate the Ignition and Growth model.The calibration is performed using an objective function based on both pressure history and the arrival time of shock.Good agreement between experimental and calculated pressure histories indicates the high accuracy of the calibrated parameters with the optimization method. | Feichao Miao Dandan Li Yangfan Cheng Junjiong Meng Lin Zhou | 2024 | Defence Technology(防务技术)2024，32，2： | 0 |
| 9 | Understanding the spatiotemporal patterns of nighttime urban vibrancy in central Shanghai inferred from mobile phone data显示文摘In recent years,major cities around the world such as New York in USA,Melbourne in Australia,and Shanghai in China,have planned to boost their nighttime urban vibrancy levels to spur the economy and achieve cultural diversity.The study of nighttime urban vibrancy from the perspective of spatiotemporal characteristics is increasingly being recognized as part of the essential work in the field of urban planning and geography.This research used mobile phone signaling records to measure urban vibrancy in central Shanghai and revealed its spatiotemporal patterns during nighttime.Specifically,this research explored the changes of urban vibrancy within a day,studied the distribution of urban vibrancy during the nighttime,and visually presented the spatiotemporal changes of nighttime urban vibrancy in central Shanghai.Moreover,on the basis of the behavior pattern of each mobile user,we classified nighttime urban vibrancy into three different types:nighttime working vibrancy,nighttime leisure vibrancy,and nighttime floating vibrancy.We then tried to determine how land use affected nighttime leisure vibrancy.The results showed that urban vibrancy in central Shanghai exhibits a periodic pattern over one-day period.A high-level nighttime urban vibrancy belt is present within central Shanghai.Business offices,hotels,entertainment and recreational districts,wholesale markets,and express services contribute most to the vibrancy at nighttime.In addition,the correlation analysis shows that public and commercial facilities generate high levels of nighttime leisure vibrancy than residential facilities.The mixed land use of public and commercial facilities and residential facilities within 500 m is more critical than the mixed use of a single land lot.The research can be a basis for supporting land use planning and providing evidence for policy-making to improve the level of nighttime urban vibrancy in cities. | ZHANG Yangfan ZHONG Weijing WANG De LIN Feng-Tyan | 2021 | Regional Sustainability2021，2，4： | 0 |
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