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1272篇 您的检索式:作者名="YAMAGISHI S"
    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2Advanced glyeation end roductsinduced apoptosis and overerpression of vascular endothelial growth factor in bovine retinal pericytes 显示文摘Yamagishi S Amano S Inagaki Y 2002Biochem Biophys Res Commun2002,290,3:1
3Telmisartan is a promising cardiometabolicsartan due to its unique PPAR-gamma-inducing property显示文摘Yamagishi S Takeuchi M 2005Med Hypotheses2005,64,3:1
4Potential therapeutic implication of nifedipine,a dihydropyridine-based calcium antagonist,in advanced glycation end product (AGE) -related disorders 显示文摘Yamagishi S Nakamura K Takeuchi M 2005Med Hypotheses2005,65,2:1
5Pigment epithelium-derived factor inhibits oxidative stress-induced apoptosis and dysfunction of cultured retinal pericytes显示文摘Amano S Yamagishi S Inagaki Y Nakamura K Takeuchi M Inoue H 2005Microvasc Res2005,69,12:1
6Concomitant laparoscopic splenectomy and cholecystectomy for management of hereditary spherocytosis associated with gallstones显示文摘Yamagishi S Watanabe T 2000Journal of clinical gastroenterology2000,30,4:1
7Comparison of inhib- itory effects of brain-derived neurotropbie factor and insulin-like growth factor on low potassium-induced apoptosis and activation of p38 MAPK and c-Jun in eultured eerebellar granule neurons显示文摘Yamagishi S Matsumoto T Yokomaku D 2003Brain Res Mol Brain Res2003,119,2:1
8Serum levels of pigment epithelium-derived factor(PEDF) are an independent determinant of insulin resistance in patients with essential hypertension显示文摘Nakamura K Yamagishi S Adachi H 2010International Journal of Cardiology2010,143,1:1
9Pigment epithelium-derived factor inhibits leptin-induced angiogenesis by suppressing vascular endothelial growth factor gene expression through anti-oxidative properties显示文摘Yamagishi S Amano S Inagaki Y 2003Microvasc Res2003,65,3:1
10Molecular mechanisms of diabetic nephropathy and its therapeutic intervention 显示文摘Yamagishi S Fukami K Ueda S 2007Curr Drug Targets2007,8,8:1
11AGEs activate mesangial TGF beta Smad signaling via an angiotensin II type I receptor interaction显示文摘Fukami K Ueda S Yamagishi S 2004Kidney Int2004,66,6:1
12查看详情显示文摘Wu C Yamagishi T Nakamoto Y Ishida S Nitta K and Kubota S 0,,:1
13Pigment epithelium-derived factor (PEDF) inhibits diabetes-or advanced glycation end product (AGE)-inducedplatelet CD40 ligand overexpression in rats显示文摘YAMAGISHI S MATSUI T UEDA S 2010Int J Cardiol2010,144,2:1
14Infection and host reaction显示文摘Mikamo H Yamagishi Y Matsubara S 2013Jpn J Antibiot2013,66,6:1
15Myelin-associated gly- coprotein inhibits micretubule assembly by a Rho-kinase-dependent mechanism显示文摘Mimura F Yamagishi S Arimura N 2006J Biol Chem2006,281,15:1
16Sorbitol dehydrogenase over-expression potentiates glucose toxicity to cultured retinal pericytes显示文摘Amano S Yamagishi SI Kato N Inagaku Y Okamoto T Makino M 2002Bio Biophy Res Commun2002,299,2:1
17Elevation of plasma matrix metalloproteinase-9 in the culprit coronary artery in patients with acute myocardial infarction: clinical evidence from distal protection 显示文摘Higo S Uematsu M Yamagishi M 2005Circ J2005,69,:1
18Advanced glycation end products-induced apoptosis of vascular endothelial growth factor and monocyte chemoattractant protein-1 in human cultured messangial cells显示文摘 Inagaki Y Okamoto T 2002J Biol Chem2002,277,20:1
19A possible involvement of crosstalk between advanced glycation end products (AGEs)and asymmetric dimethylarginine(ADMA),an endogenous nitric oxide synthase inhibitor in accelerated atherosclerosis in diabetes显示文摘Yamagishi S Ueda S Okuda S 2007Med Hypotheses2007,69,4:1
20Molecular mechanisms of diabetic nephropathy and its therapeutic intervention显示文摘Yamagishi S Fukami K Ueda S 2007Curt Drug Targets2007,8,8:1
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