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| 1 | A 3D Geological Model Constrained by Gravity and Magnetic Inversion and its Exploration Implications for the World-class Zhuxi Tungsten Deposit, South China显示文摘The Zhuxi tungsten deposit in Jiangxi Province,South China,contains a total W reserve of about 2.86 Mt at an average grade of 0.54 wt%WO3,representing the largest W deposit in the world.Numerous studies on the metallogeny of the deposit have included its timing,the ore-controlling structures and sedimentary host rocks and their implications for mineral exploration.However,the deep nappe structural style of Taqian-Fuchun metallogenic belt that hosts the W deposit,and the spatial shape and scale of deeply concealed intrusions and their sedimentary host rocks are still poorly defined,which seriously restricts the discovery of new deposits at depth and in surrounding areas of the W deposit.Modern 3 D geological modeling is an important tool for the exploration of concealed orebodies,especially in brownfield environments.There are obvious density contrast and weak magnetic contrast in the ore-controlling strata and granite at the periphery of the deposit,which lays a physical foundation for solving the 3 D spatial problems of the ore-controlling geological body in the deep part of the study area through gravity and magnetic modeling.Gravity data(1:50000)and aeromagnetic data(1:50000)from the latest geophysical surveys of 2016-2018 have been used,firstly,to carry out a potential field separation to obtain residual anomalies for gravity and magnetic interactive inversion.Then,on the basis of the analysis of the relationship between physical properties and lithology,under the constraints of surface geology and borehole data,human-computer interactive gravity and magnetic inversion for 18 cross-sections were completed.Finally,the 3 D geological model of the Zhuxi tungsten deposit and its periphery have been established through these 18 sections,and the spatial shape of the intrusions and strata with a depth of 5 km underground were obtained,initially realizing―transparency‖for ore-controlling bodies.According the analysis of the geophysical,geochemical,and geological characteristics of the Zhuxi tungsten deposit,we discern three principles for prospecting and prediction in the research area,and propose five new exploration targets in its periphery. | YAN Jiayong LÜ Qingtian QI Guang FU Guangming ZHANG Kun LAN Xueyi GUO Xin WEI Jin LUO Fan WANG Hao WANG Xu | 2020 | Acta Geologica Sinica(English Edition)2020，94，6： | 3 |
| 2 | Efficacy and Safety of Dexamethasone Ointment on Recurrent Aphthous Ulceration显示文摘 | Chuanxia Liu Zengtong Zhou Guanjian Liu Qintao Wang Jiangang Chen Ling Wang Yongmei Zhou Guangying Dong Xueyi Xu Yuechun Wang Yiqing Guo Mei Lin Lan Wu Gefei Du Changlei Wei Xin Zeng Xiaoyi Wang Junzheng Wu Bingqi Li Gang Zhou Hongmei Zhou | 2012 | The American Journal of Medicine2012，，3： | 1 |
| 3 | Deep Mineralization Background and Metallogenic Regularity of the Tongling Ore District显示文摘Based on the geological conditions and characteristics of mineralization present,three-dimensional geological modelling is used in conjunction with previous deep research results,in order to discuss the process of deep mineralization in the Tongling ore district.The structural analysis shows that surface deformation is strong,deep deformation is weak,the surface has mainly experienced brittle deformation,with the possibility of a large number of deep ductile deformations.There is a thrust nappe between the Tongling uplift and the Nanling basin,that is the boundary of the Tongling block,which has resulted in the southwest uplift of the Tongling block.Combined with the deep exploration data,the threedimensional shape of the main rock masses is interpreted,with three-layer structures in the deep magma chamber.The spatial distribution of magmatic rocks is mainly controlled by the structure.The movement of magmatic hydrothermal fluid is dominated by mesoscale seepage in the deep part and'dike'type upwelling in the shallow part.There is a certain coupling relationship between the ore-forming rock mass and the surrounding rock.The ore-forming age is dominated by the Yanshanian period.Based on the distribution,types and metallogenic characteristics of the deposits,the metallogenic model of'layer coupling'in the Tongling ore district is summarized,with the'one body,two belts and a multilayer metallogenic system'is established,which is significant for the future direction of deep prospecting in the Tongling area. | WAN Qiu DU Jianguo YANG Bo LAN Xueyi XIAO Xiao SHI Ke | 2020 | Acta Geologica Sinica(English Edition)2020，94，6： | 0 |
| 4 | A 3D Investigation of Geological Structure and Its Relationship to Mineralization in the Nanling-Xuancheng Ore District,Middle-Lower Yangtze River Metallogenic Belt,China显示文摘The Nanling-Xuancheng ore region of Anhui Province is located in the Middle-Lower Yangtze River metallogenic belt.Insufficient exploration and research have been carried out in this newly defined ore district,although the Chating large porphyry Cu-Au deposit and a few middle-sized skarntype Cu polymetallic deposits have been discovered.In this study,we carried out high-resolution seismic reflection,magnetotelluric,gravity,and magnetic investigations,and constructed the 3 D geological structure of the uppermost crust in a depth range of 0-5 km using a comprehensive inversion of the new data constrained by previous deep-drilling data.We hence proposed some new insights to understand the mineralization processes of this district.A system of alternating ridges and valleys is suggested as the major structure pattern,composed of“two-layer structure”of the basins and“three-layer structure”of anticlines.Moreover,a conjugated fault system and its distribution features are revealed in our models,including the Jiangnan fault,Zhouwang fault,and Kunshan thrust nappe.The Jiangnan and Kunshan faults are suggested to have controlled the diagenesis and metallogenesis.Two deep concealed plutons located in Chating and Magushan are found,forming the Mesozoic diorite-felsic intrusions.These intrusions are believed to be the causes of hydrothermal deposits such as the Chating deposit and the Magushan deposit. | Sanming Lu Xueyi Lan Lili Zhao Zanzan Zhang Xiaoyong Yang Zhuang Zhao Dong Guo Xiaochun Xu Yongsheng Wang Jianshe Li Huasheng Qi | 2022 | Journal of Earth Science2022，33，3： | 0 |
| 5 | Systematic review on the adverse reactions of oral administration of Indigo Naturalis and its preparations显示文摘Objective:This article systematically analyses the effects of adverse drug events/adverse drug reactions(ADEs/ADRs)of oral Indigo Naturalis(Qingdai)preparations in order to provide references for its rational clinical application.Methods:All clinical studies reporting ADE/ADR related to the oral administration of Qingdai preparations were searched through electronic databases,including PubMed,the Cochrane Library,Embase,China National Knowledge Infrastructure(CNKI),China Biology Medicine disc(CBM),VIP Information Chinese Journal Service Platform(VIP),and Wanfang database,from inception to September 27,2020.Information were extracted from these literatures,including primary disease,type of adverse reactions,dose,treatment,outcomes and so on.Incidence of ADE/ADR was estimated,as well as distribution of primary diseases and victim organs and systems were analyzed.Results:A total of 682 articles were included,with 651 clinical population studies and 31 case reports.Among them,604 detailed ADR/AE involving 33459 patients using oral Qingdai preparations,and a total of 5061 cases were found to present adverse events,including 2827 cases of digestive system(abdominal pain,diarrhea,etc.),469 cases of blood system damage(thrombocytopenia,leukopenia,anemia,etc.),313 cases of liver damage(abnormal liver function,liver toxicity,elevated liver enzymes,etc.),327 cases of nervous system reactions(headache,dizziness,poor sleep,etc.)and 1186 cases of other systems and organs.Severe adverse events(SAEs)mainly were liver damage,and could be relived after symptomatic treatment.Conclusion:From the systematic information retrieval and analysis,it is found that oral Qingdai preparations application may clinically cause ADEs/ADRs in terms of gastrointestinal tract and liver damage.Therefore,when using oral Qingdai preparations,liver and stomach protection should be done.At the same time,pay close attention to various biochemical indicators and the patient's drug response during the treatment process,and,if necessary,deal with it in time so as not to deteriorate the condition.Moreover,active surveillance system should be conducted to monitor ADE/ADR,so as to establish a clearer causal relationship between the drug and the adverse event. | Xueyi Deng Rui Lan Qianwen Xie Jingmin Xiao Jiaqi Lai Jing Chen Yihan He Shaonan Liu Lihong Yang Xinfeng Guo | 2021 | TMR Modern Herbal Medicine2021，4，1： | 0 |
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