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| 1 | Effects of Sini San used alone and in combination with fluoxetine on central and peripheral 5-HT levels in a rat model of depression显示文摘OBJECTIVE: To investigate the effects of Sini San and fluoxetine on the levels of central and peripheral 5-HT in a rat model of depression, and provide new insight into the treatment of depression with integrated Chinese-Western Medicine.METHODS: A rat model of depression was established by chronic mild stress(CMS). Model rats received either Sini San, fluoxetine, a combination of the two drugs, or no drug treatment. Healthy naive rats were used as controls. Open field and sucrose preference tests were used to assess depression-like behavior. ELISA and immunohistochemistry were used to determine central and peripheral levels of 5-HT.RESULTS: In the group with no drug treatment,central 5-HT expression decreased while peripheral5-HT concentrations increased as CMS continued.Four weeks after CMS, Sini San alone was less effective in reducing depression-like behavior than fluoxetine alone or in combination with Sini San,but combined use was more effective than fluoxetine alone. Eight weeks after CMS, Sini San alone or in combination with fluoxetine was more effective in reducing depression-like behavior than fluoxetine alone. Furthermore Sini San and fluoxetine used alone or in combination notably increased central 5-HT expression and decreased peripheral 5-HT levels in the rat model.CONCLUSION:The results of the present study indicate that there is a synergistic action between the two medicines in the treatment of depression. Sini San exhibited a relatively long lag before its effects were observed; however, by eight weeks the Traditional Chinese Medicine appeared at least as effective as fluoxetine. We suggest that Sini San can replace fluoxetine in the later stages of depression treatment to minimize side effects observed with long-term fluoxetine administration. | Yubo Li Yuxiu Sun Xueling Ma Xiaoxing Xue Wenting Zhang Zhiqian Wu Yulin Ouyang Jianxin Chen Weiming Wang Shuzhen Guo Wei Wang | 2013 | Journal of Traditional Chinese Medicine2013,33,5: | 6 |
| 2 | ON (∈,∈ ∨q)-FUZZY FILTERS OF BL-ALGEBRAS显示文摘作者介绍() 的观点模糊布尔(含蓄,积极含蓄,;奇妙) 在 BL 代数学的过滤器,在这些概括模糊过滤器上介绍一些描述,;在这些概括模糊过滤器之中描述关系。它被证明那在 BL 代数学的模糊过滤器是的() 布尔(含蓄) 如果;仅当它两个都是积极的含蓄;奇妙。 | Xueling MA Jianming ZHAN | 2008 | Journal of Systems Science & Complexity2008,21,1: | 5 |
| 3 | Effective and precise adenine base editing n mouse zygotes显示文摘 | Puping Liang Hongwei Sun Xiya Zhang Xiaowei Xie Jinran Zhang Yaofu Bai Xueling Ouyang Shengyao Zhi Yuanyan Xiong Wenbin Ma Dan Liu Junjiu Huang Zhou Songyang | 2018 | Protein & Cell2018,9,9: | 4 |
| 4 | Research progress on properties of pre-gelatinized starch and its application in wheat flour products显示文摘Starch is the most abundant organic compound in nature,second only to cellulose.However,the conserved structure of native starches limits their properties and applications.Therefore,it is often necessary to modify them to obtain specific properties.As a common green and safe physical modification method,pre-gelatinization can improve the cold water solubility and swelling power of starch.The typical preparation methods of pre-gelatinized starch include spray drying,extrusion,and drum drying.Spray-dried pre-gelatinized starch still had good granule shape,but the increase of cold water solubility and cold paste viscosity was relatively small.Extruded and drum-dried pre-gelatinized starch showed serious structure destruction,significant increases in cold water solubility and cold paste viscosity,but relatively low hot paste viscosity.The properties of pre-gelatinized starch obtained by different methods are different,so do their effects on the quality of flour products.Wheat flour products,as one of the leading staple food for the people all over the world,play a vital role in people's daily life.With the improvement of people's living standards,more and more special flour products with unique features have received attentions of consumers and researchers.However,the sensory characteristics of special flour products are often inferior to traditional flour products,which limits its development.The unique functional characteristics of pre-gelatinized starch make it expected to play an essential role in the quality improvement of featured flour products.In this paper,the granule morphology,crystal structure,hydration and gelatinization properties of pre-gelatinized starch prepared by three common methods and their application in flour products were reviewed,which provides a theoretical basis for the application of pre-gelatinized starch in food industry. | Hao Ma Mei Liu Ying Liang Xueling Zheng Le Sun Wenqian Dang Jie Li Limin Li Chong Liu | 2022 | Grain & Oil Science and Technology2022,5,2: | 3 |
| 5 | GENERALIZED FUZZY FILTERS OF BL-ALGEBRAS显示文摘有珍视的模糊集合被考虑的间隔的模糊间隔价值的伪巧合的概念。事实上,这是有一个模糊集合的一个模糊的点的伪巧合的归纳。由使用这个新想法,间隔的观点珍视(∈,∈∨ q ) 在是 BL 代数学的模糊过滤器的归纳的 BL 代数学的模糊过滤器,被定义,;相关性质被调查。特别地,有阀值的模糊亚群的概念被扩大到间隔的概念有在 BL 代数学的阀值的珍视的模糊过滤器。 | Ma Xueling Zhan Jianming Xu Yang | 2007 | Applied Mathematics(A Journal of Chinese Universities)2007,22,4: | 3 |
| 6 | Combined incisional ropivacaine infiltration and pulmonary recruitment manoeuvre for postoperative pain relief after diagnostic hysteroscopy and laparoscopy显示文摘 | Liu Huili Ma Caihong Zhang Xiaoqing Yu Chen Yang Yan Song Xueling Tang Yi Guo Xiangyang | 2014 | Chinese Medical Journal2014,,5: | 3 |
| 7 | ON FUZZY h-IDEALS OF HEMIRINGS显示文摘在珍视的模糊集合被考虑的间隔的模糊间隔值的伪巧合的概念。事实上,这个概念是在一个模糊集合的一个模糊的点的伪巧合的一个概括概念。由使用这个新概念,作者定义间隔的观点珍视半的模糊 h 理想包围的() ;学习他们的相关性质。另外,作者也与阀值扩大模糊亚群的概念到珍视的间隔的概念模糊与在半戒指的阀值 h 理想。 | Xueling MA and Jianming ZHAN | 2007 | Journal of Systems Science & Complexity2007,20,3: | 2 |
| 8 | Construction thoughts and practice of Traditional Chinese Medicine nursing inheritance work显示文摘Master-apprentice system is a main mode of talent cultivation for Traditional Chinese medicine(TCM). To vigorously push forward inheritance and innovation of TCM nursing, Beijing Administration of Traditional Chinese Medicine carried out TCM nursing inheritance work in 2016, establishing 3 studios and 1 workstation. In this paper, we summarized constructional methods and achievements in TCM nursing inheritance studios and workstation, raised issues during working, and thought about how to work in the next stage, in hoping to lay a good foundation for carrying out in-depth work about TCM nursing inheritance. | TANG Ling MA Xueling ZHANG Xuejian DENG Jianhua ZHANG Jing LIU Yiyuan ZHU Jing | 2019 | 中西医结合护理(中英文)2019,5,12: | 2 |
| 9 | Generalized fuzzy h-bi-ideals and h-quasi-ideals of hemirings 显示文摘 | Ma Xueling Zhan Jianming | 2009 | Information Sciences2009,179,9: | 1 |
| 10 | Biochip as a potential platform of serological interferon a2b antibody assay 显示文摘 | Du Weidong Xu Zhenshan Ma Xueling | 2003 | Journal of Biotechnology2003,106,: | 1 |
| 11 | Biochip as a potential interferon a2b antibody assay 显示文摘 | Weidong Du Zhenshan Xu Xueling Ma | 2003 | J Biotechnol2003,106,1: | 1 |
| 12 | Limiting explosible concentration of hydrogen-oxygen-helium mixtures related to the practical operational case显示文摘 | Liu Xueling Zhang Qi Ma Qiuju | 2014 | Journal of Loss Prevention in the Process Industries2014,29,: | 1 |
| 13 | Intuitionistic fuzzy ideals of incline algebras显示文摘 | Ma Xueling Zhan Jianming | 2005 | Sci Math Jpn2005,62,1: | 1 |
| 14 | Doubt fuzzy subinclines(ideals)of incline algebras显示文摘 | Zhan Jianming Ma Xueling | 2005 | Sci Math2005,61,2: | 1 |
| 15 | A novel voltammetric sensor for ascorbic acid based on molecularly imprinted poly( o -phenylenediamine- co - o -aminophenol)显示文摘 | Yong Kong Xueling Shan Jianfeng Ma Meilan Chen Zhidong Chen | 2013 | Analytica Chimica Acta2013,,: | 1 |
| 16 | Community Characteristics and Species Diversity of Wetland Plants in the Yangguan Nature Reserve of Dunhuang显示文摘As a typical inland wetland, Yangguan nature reserve wetland in Dunhuang is one of the important stops of migratory route for birds, which is vulnerable and particular. Study on the community characteristics and species diversity of wetland has great signifi cance for biodiversity protection. Based on the fi eld investigation, the fl oristic composition, geographical elements and species diversity of wetland plants were studied in Yangguan reserve of Dunhuang. The results showed that 26 families, 56 genera and 74 species were recorded in the study area. The largest families were the Gramineae and Chenopodiaceae, accounting for 29.73% of the total. Herbs were the most abundant life-form, accounting for 77.03% of the total. The fl oral geographical elements of the plants were mainly composed of temperate zone distribution type. By using two way indicator species analysis(TWINSPAN), the vegetation in 36 sampling plots could be classifi ed into 8 communities. The species diversity indexes of communities were relatively low, but had large differences among each other. According to the importance value, the Margalef richness index(Rm) ranged from 0 to 4.200. Simpson diversity index(D) was between 0 and 0.512; Shannon diversity index(H) ranged from 0 to 1.400, and Pielou evenness index(J) was within the range of 0.538 to 1.000. The results indicated that the plant species were relatively rare and simple in general, the species diversity of communities was low, and the ecological environment was fragile in Yangguan nature reserve of Dunhuang. | DAI Xueling ZHAO Tingwei MA Shoushi LIU Xingwen YANG Jinwu MA Haitao HE Wenli YANG Jing DUAN Hongling XIE Jianping | 2016 | Journal of Landscape Research2016,8,2: | 1 |
| 17 | Fuzzy deductive sys- tems of HS-algebras显示文摘 | ZHAN Jianming MA Xueling | 2005 | Sci Math Jpn2005,61,2: | 1 |
| 18 | Stability of loess high-fill slope based on monitored soil moisture changes显示文摘This paper aims to assess the influence of moisture content changes during rainfall on the stability of loess high-fill slopes by taking a loess high-fill slope in Lanzhou City as an example.First,according to the moisture content monitoring data collected from a slope online monitoring system,direct shear tests were performed on soil samples of different moisture content to determine the relationship between the shear strength parameters and moisture content.Next,a coupled hydro-mechanical model with soil shear strength related to moisture content was established and used to analyze 16 working conditions with various rainfall intensities and durations for two cases:shear strength parameters from the site exploration report and those from this study.Finally,the results from the two cases were compared regarding the changes in stresses and displacements after rainfall infiltration to analyze the influence of moisture content on the stability of loess high-fill slopes.The conclusions are as follows:(1)Segmental relationship equations of cohesion and angle of internal friction were established for loess with various moisture content.(2)Under the conditions of different rainfall intensities,significant differences were observed in the trends of slope stress and displacement changes.(3)The slope displacement occurred in the shallow soil layer within about 12.5 m from the slope top,and the plastic strain concentrated in the soil layer within about 6 m from the slope top.(4)The results of slope stability analyses based on moisture content monitoring data are more in line with the observed. | XueLing Yong Yu Zhang YunLong Hou BingBing Han Ning An Hui Zhang Ying Ma | 2023 | Research in Cold and Arid Regions2023,15,4: | 0 |
| 19 | The effect of different cancer therapies on clinical outcomes of assisted reproductive technology in breast cancer patients显示文摘Objective To evaluate the clinical outcomes of assisted reproductive technology(ART)on fertility preservation and infertility treatment in breast cancer patients who had undergone different cancer therapies.Methods 20 infertile females who had undergone breast cancer treatments during 2011–2018 were studied retrospectively.The patients were divided into two groups based on their cancer treatment methods and their needs of fertility preservation:the combined treatment group,who had both breast cancer surgery combining with any of the three treatments(adjuvant endocrine therapy,radiotherapy or chemotherapy),and the surgery only group.A group of infertile females without breast cancer history were used as a control group.An aromatase inhibitor Letrozole-based ovarian micro-stimulation protocol was used in females from the three groups for in vitro fertilization and embryo transfer.The ART clinical outcomes were evaluated by using the parameters of antral follicle count(AFC),the ratio of FSH/LH,oocyte retrieval number,2 pronucleus(2 PN)fertilization rate,high-quality embryo rate,clinical pregnancy rate,and delivery outcome.Results The surgery only group had significantly lower ratio of FSH/LH than the combined treatment group and the control group.No significant difference on the ART clinical outcomes,evaluated by the aforementioned criteria,were found between the three groups.Conclusions Breast cancer surgery with adjuvant therapies,but not surgery alone,may damage ovarian function.The best time-limited window to preserve fertility for breast cancer patients is after surgery but before the initiation of adjuvant therapies.Importantly,the clinical outcomes of aromatase inhibitor-based ovary micro-stimulation in breast cancer patients are similar to that in non-breast cancer controls. | Mengmeng Zhang Xueling Song Caihong Ma Xiumei Zhen Hongbin Chi Xiaowei Zhang Rong Li Jie Yan Jie Qiao | 2021 | Gynecology and Obstetrics Clinical Medicine2021,1,1: | 0 |
| 20 | The effect of continuous Jue tone intervention on blood pressure and vasoactive substances in hypertensive rats with a liver-fire hyperactivity pattern显示文摘Objective:Jue tone is a kind of sound,using 3-mi as the main tone,and is melodious,profound,makes people feel comfortable and pleasant.This study aimed to explore the probable mechanism of Jue tone to reduce blood pressure(BP)in hypertensive rats with a liver-fire hyperactivity pattern by observing changes in BP as well as physiochemical indexes in plasma.Methods:Sixteen male spontaneous hypertensive rats(SHR)with a liver-fire hyperactivity pattern were randomly divided into a control group and a Jue tone group.The rats in the Jue tone group were treated with Jue tone(55e65 dB,played by the five elements of music rhythm instrument,a kind of physiotherapy regimen music played by Shen Wu)once a day for 4 weeks.The BP levels in each group were measured twice a week,on Monday and Friday.The levels of angiotensin II(Ang-II),thromboxane B2(TXB2),endothelin-1(ET-1),calcitonin gene-related peptide(cGRP),norepinephrine(NE),cortisol(CORT),and 5-hydroxytryptamine(5-HT).in plasma were detected by enzyme-linked immunosorbent assay after 4 weeks of intervention.Results:BP and the levels of TXB2 and ET-1 in the plasma of the treatment group were significantly lower than those of the control group,while the level of cGRP was significantly higher.Conclusion:Jue tone can reduce the BP of hypertensive rats with a liver-fire hyperactivity pattern.The mechanism may correlate with a reduction in TXB2 and ET-1 and an increase in cGRP with the reduction of reactive oxygen species(ROS). | Qian Zhou Yufeng Chen Sitong Zhang Pei Yang Tian Wang Jianxin Chen Huihui Zhao Wei Wang Xueling Ma | 2022 | Journal of Traditional Chinese Medical Sciences2022,9,1: | 0 |