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| 1 | Automatic Navigation for Rat-Robots with Modeling of the Human Guidance显示文摘 | Chao Sun Nenggan Zheng Xinlu Zhang Weidong Chen Xiaoxiang Zheng | 2013 | Journal of Bionic Engineering2013，10，1： | 5 |
| 2 | Identification of Styryl Sulfonyl Fluoride as a Near-Perfect Michael Acceptor for Diversified Protein Bioconjugations显示文摘Cysteine(Cys)-specific bioconjugation has widespread applications in the synthesis of protein conjugates,particularly for the functionalization of antibodies.Here,we report the discovery of transstyryl sulfonyl fluoride(SSF)as a near-perfect Michael acceptor for Cys-specific protein bioconjugation.Compared to maleimides,which are predominantly used,SSF exhibited better chemoselectivity,selfstability,and conjugate stability while maintaining comparable reactivity.Using SSF-derived probes,proteins can be readily modified on the Cys residue(s)to install functionalities,for example,fluorescent dyes,toxins,and oligonucleotides,without influencing the activity.Further applications of SSF-derived serum-stable antibody-drug conjugates and PD-L1 nanobody-oligo conjugates demonstrate the great translational value of SSF-based bioconjugation in drug development and single-cell sequencing. | Qingsong Wu Qi Xue Ji Li Qinheng Zheng Xinlu Zhao Wannan Li Shiming Sun Wanxing Sha Yang Yang Yi Yang Jie P.Li | 2023 | CCS Chemistry2023，5，10： | 0 |
| 3 | The global mismatch between equitable carbon dioxide removal liability and capacity显示文摘Limiting climate change to 1.5℃and achieving net-zero emissions would entail substantial carbon dioxide removal(CDR)from the atmosphere by the mid-century,but how much CDR is needed at country level over time is unclear.The purpose of this paper is to provide a detailed description of when and how much CDR is required at country level in order to achieve 1.5℃and how much CDR countries can carry out domestically.We allocate global CDR pathways among 170 countries according to 6 equity principles and assess these allocations with respect to countries'biophysical and geophysical capacity to deploy CDR.Allocating global CDR to countries based on these principles suggests that CDR will,on average,represent~4%of nations'total emissions in 2030,rising to~17%in 2040.Moreover,equitable allocations of CDR,in many cases,exceed implied land and carbon storage capacities.We estimate~15%of countries(25)would have insufficient land to contribute an equitable share of global CDR,and~40%of countries(71)would have insufficient geological storage capacity.Unless more diverse CDR technologies are developed,the mismatch between CDR liabilities and land-based CDR capacities will lead to global demand for six GtCO_(2)carbon credits from 2020 to 2050.This demonstrates an imperative demand for international carbon trading of CDR. | Pu Yang Zhifu Mi Yi-Ming Wei Steef V.Hanssen Lan-Cui Liu D’Maris Coffman Xinlu Sun Hua Liao Yun-Fei Yao Jia-Ning Kang Peng-Tao Wang Steven J.Davis | 2023 | National Science Review2023，10，12： | 0 |
| 4 | Sinistral strike slip of the Zhangjiakou-Penglai Fault and its control on hydrocarbon accumulation in the northeast of Shaleitian Bulge,Bohai Bay Basin,East China显示文摘The structural style, fault activity, strike-slip displacement, and the formation mechanism and hydrocarbon migration and accumulation in the center tectonic zone in the northeast Shaleitian Bulge of Zhangjiakou-Penglai Fault Zone were studied by seismic attribute analysis, structural geometric analysis, fault activity analysis, structure evolution history and simulation of hydrocarbon migration, based on 3-D seismic and drilling data. The main results are as follows:(1) The study area is a superimposed tectonic zone, which experienced early(Paleocene and Eocene) extension and late(Oligocene and Pliocene-Quaternary) strike-slip and pull-apart.(2) The sinistral strike slip of the northeast Shaleitian Bulge of Zhangjiakou-Penglai Fault Zone went through two periods, Oligocene and Pliocene-Quaternary, and the Bohai section was active earlier than the inland section.(3) The sinistral strike slip displacement of Zhangjiakou-Penglai Fault is 4 km since Cenozoic, including 1 km in the Oligocene, and 3 km in the Pliocene-Quaternary.(4) The strike-slip movements have resulted in the increase of fault activity and basin-mountain restructure in the fault zone, also contributed to the formation of the central tectonic belt and the conjugate evolution in north-east structural belt.(5) The conjugate strike slip of the Zhangjiakou-Penglai Fault Zone dominated the migration and accumulation of hydrocarbon in shallow formations by controlling the injection points and segments of hydrocarbon from the deep layers to shallow layers. | PENG Jingsong WEI Ajuan SUN Zhe CHEN Xinlu ZHAO Dijiang | 2018 | Petroleum Exploration and Development2018，45，2： | 0 |
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