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| 1 | New insights into eutrophication management:Importance of temperature and water residence time显示文摘Eutrophication and harmful cyanobacterial blooms threaten water resources all over the world.There is a great controversy about controlling only phosphorus or controlling both nitrogen and phosphorus in the management of lake eutrophication.The primary argument against the dual nutrients control of eutrophication is that nitrogen fixation can compensate the nitrogen deficits.Thus,it is of great necessary to study the factors that can significantly affect the nitrogen fixation.Due to the difference of climate and human influence,the water quality of different lakes(such as water temperature,N:P ratio and water residence time)is also quite different.Numerous studies have reported that the low N:P ratio can intensify the nitrogen fixation capacities.However,the effects of temperature and water residence time on the nitrogen fixation remain unclear.Thus,30 shallows freshwater lakes in the eastern plain of China were selected to measure dissolved N_(2) and Ar concentrations through N_(2):Ar method using a membrane inlet mass spectrometer to quantify the nitrogen fixation capacities and investigate whether the temperature and water residence time have a great impact on nitrogen fixation.The results have shown that the short lake water residence time can severely inhibit the nitrogen fixation capacities through inhibiting the growth of nitrogenfixing cyanobacteria,changing the N:P ratio and resuspending the solids from sediments.Similarly,lakes with low water temperature also have a low nitrogen fixation capacity,suggesting that controlling nitrogen in such lakes is feasible if the growth of cyanobacteria is limited by nitrogen. | Feng Zhao Xu Zhan Hai Xu Guangwei Zhu Wei Zou Mengyuan Zhu Lijuan Kang Yulong Guo Xingchen Zhao Zicong Wang Wei Tang | 2022 | Journal of Environmental Sciences2022，34，1： | 2 |
| 2 | The interaction between Ag + and bovine serum albumin: A spectroscopic investigation显示文摘 | Xingchen Zhao Rutao Liu Yue Teng Xiaofang Liu | 2010 | Science of the Total Environment2010，，5： | 1 |
| 3 | Cooperative interactions among CTA^+, Br^-and Ag^+ during seeded growth of gold nanorods显示文摘我们在由第四级的铵卤化物和钠油酸盐(NaOL ) 组成的二进制表面活化剂混合物在 Au nanorods (AuNRs ) 的形成机制上执行了全面研究。我们在指导 AuNRs 的各向异性的生长作为关键成分识别 cetyltrimethyl 铵(CTA )-Br-Ag+ 建筑群。在我们推进的 CTA +, Br -和 Ag +,之中基于合作相互作用的改进理解乐意地表明那 AgBr ,它是由 cetyltrimethyl 铵溴化物( CTAB )或 cetyltrimethyl 铵氯化物( CTAC )的 solubilized 微粒,能为 AuNRs 的准备作为 Ag +和 Br -的联合来源被采用。高质量的 AuNRs 的生长能在极其低的溴化物内容(0.1 公里) 下面在 15 min 以内被完成。 | Yong Xu Lei Chen Xingchen Ye Xuchun Wang Jiaqi Yu Yang Zhao Muhan Cao Zhouhui Xia Baoquan Sun Qiao Zhang | 2017 | Nano Research2017，10，6： | 1 |
| 4 | Enhanced room-temperature Naþionic conductivity in Na_(4.92)Y_(0.92)Zr_(0.08)Si_(4)O_(12)显示文摘Developing cost-effective and reliable solid-state sodium batteries with superior performance is crucial for stationary energy storage.A key component in facilitating their application is a solid-state electrolyte with high conductivity and stability.Herein,we employed aliovalent cation substitution to enhance ionic conductivity while preserving the crystal structure.Optimized substitution of Y^(3+)with Zr^(4+)in Na_(5)YSi_(4)O_(12) introduced Naþion vacancies,resulting in high bulk and total conductivities of up to 6.5 and 3.3 mS cm^(-1),respectively,at room temperature with the composition Na_(4.92)Y_(0.92)Zr_(0.08)Si_(4)O_(12)(NYZS).NYZS shows exceptional electrochemical stability(up to 10 V vs.Naþ/Na),favorable interfacial compatibility with Na,and an excellent critical current density of 2.4 mA cm^(-2).The enhanced conductivity of Naþions in NYZS was elucidated using solid-state nuclear magnetic resonance techniques and theoretical simulations,revealing two migration routes facilitated by the synergistic effect of increased Naþion vacancies and improved chemical environment due to Zr^(4+)substitution.NYZS extends the list of suitable solid-state electrolytes and enables the facile synthesis of stable,low-cost Naþion silicate electrolytes. | Aikai Yang Kai Yao Mareen Schaller Enkhtsetseg Dashjav Hang Li Shuo Zhao Qiu Zhang Martin Etter Xingchen Shen Huimin Song Qiongqiong Lu Ruijie Ye Igor Moudrakovski Quanquan Pang Sylvio Indris Xingchao Wang Qianli Ma Frank Tietz Jun Chen Olivier Guillon | 2023 | eScience2023，3，6： | 0 |
| 5 | Environmental sustainability opportunity and socio-economic cost analyses of phosphorus recovery from sewage sludge显示文摘Although phosphorus(P)recovery and management from sewage sludge are practiced in North America and Europe,such practices are not yet to be implemented in China.Here,we evaluated the environmental sustainability opportunity and socio-economic costs of recovering P from sewage sludge by replacing the current-day treatments(CT;sludge treatment and landfill)and P chemical fertilizer application(CF)in China using life cycle assessment and life cycle costing methods.Three potential P recovery scenarios(PR1‒PR3:struvite,vivianite,and treated sludge)and corresponding current-day scenarios(CT1‒CT3 and CF)were considered.Results indicated that PR1 and PR2 have smaller environmental impacts than the current-day scenarios,whereas PR3 has larger impacts in most categories.PR3 has the lowest net costs(sum of internal costs and benefits,39.1-54.7 CNY per kg P),whereas PR2 has the lowest external costs(366.8 CNY per kg P).Societal costs for production and land use of 1 kg P by P recovery from sewage sludge(e.g.,∼527 CNY for PR1)are much higher than those of P chemical fertilizers(∼20 CNY for CF).However,considering the costs in the current-day treatments(e.g.,∼524 CNY for CT1),societal costs of P recovery scenarios are close to or slightly lower than those of current-day scenarios.Among the three P recovery scenarios,we found that recovering struvite as P fertilizer has the highest societal feasibility.This study will provide valuable information for improved sewage sludge management and will help promote the sustainable supply of P in China. | Jiawen Xie Xingchen Zhuge Xixi Liu Qian Zhang Yiwen Liu Peizhe Sun Yingxin Zhao Yindong Tong | 2023 | Environmental Science and Ecotechnology2023，，4： | 0 |
| 6 | Imaging through scattering media via spatial-temporal encoded pattern illumination显示文摘Optical imaging through scattering media has long been a challenge.Many approaches have been developed for focusing light or imaging objects through scattering media,but usually,they are either invasive,limited to stationary or slow-moving media,or require high-resolution cameras and complex algorithms to retrieve the images.By utilizing spatial-temporal encoded patterns(STEPs),we introduce a technique for the computation of imaging that overcomes these restrictions.With a single-pixel photodetector,we demonstrate non-invasive imaging through scattering media.This technique is insensitive to the motion of the media.Furthermore,we demonstrate that our image reconstruction algorithm is much more efficient than correlation-based algorithms for single-pixel imaging,which may allow fast imaging for applications with limited computing resources. | XINGCHEN ZHAO XIAOYU NIE ZHENHUAN YI TAO PENG MARLAN O.SCULLY | 2022 | Photonics Research2022，10，7： | 0 |
| 7 | Data-Driven Control of Linear Systems via Quantized Feedback显示文摘Quantized feedback control is fundamental to system synthesis with limited communication capacity.In sharp contrast to the existing literature on quantized control which requires an explicit dynamical model,the authors study the quadratic stabilization and performance control problems with logarithmically quantized feedback in a direct data-driven framework,where the system state matrix is not exactly known and instead,belongs to an ambiguity set that is directly constructed from a finite number of noisy system data.To this end,the authors firstly establish sufficient and necessary conditions via linear matrix inequalities for the existence of a common quantized controller that achieves our control objectives over the ambiguity set.Then,the authors provide necessary conditions on the data for the solvability of the LMIs,and determine the coarsest quantization density via semi-definite programming.The theoretical results are validated through numerical examples. | LI Xingchen ZHAO Feiran YOU Keyou | 2024 | Journal of Systems Science & Complexity2024，37，1： | 0 |
| 8 | RING finger 138 deregulation distorts NF-κB signaling and facilities colitis switch to aggressive malignancy显示文摘Prolonged activation of nuclear factor(NF)-кB signaling significantly contributes to the development of colorectal cancer(CRC).New therapeutic opportunities are emerging from targeting this distorted cell signaling transduction.Here,we discovered the critical role of RING finger 138(RNF138)in CRC tumorigenesis through regulating the NF-кB signaling,which is independent of its Ubiquitin-E3 ligase activity involved in DNA damage response.RNF138^(−/−) mice were hyper-susceptible to the switch from colitis to aggressive malignancy,which coincided with sustained aberrant NF-кB signaling in the colonic cells.Furthermore,RNF138 suppresses the activation of NF-кB signaling pathway through preventing the translocation of NIK and IKK-Beta Binding Protein(NIBP)to the cytoplasm,which requires the ubiquitin interaction motif(UIM)domain.More importantly,we uncovered a significant correlation between poor prognosis and the downregulation of RNF138 associated with reinforced NF-кB signaling in clinical settings,raising the possibility of RNF138 dysregulation as an indicator for the therapeutic intervention targeting NF-кB signaling.Using the xenograft models built upon either RNF138-dificient CRC cells or the cells derived from the RNF138-dysregulated CRC patients,we demonstrated that the inhibition of NF-кB signaling effectively hampered tumor growth.Overall,our work defined the pathogenic role of aberrant NF-кB signaling due to RNF138 downregulation in the cascade events from the colitis switch to colonic neoplastic transformation and progression,and also highlights the possibility of targeting the NF-кB signaling in treating specific subtypes of CRC indicated by RNF138-ablation. | Yalan Lu Rong Huang Jianming Ying Xingchen Li Tao Jiao Lei Guo Haitao Zhou Han Wang Amannisa Tuersuntuoheti Jianmei Liu Qichen Chen Yanhong Wang Luying Su Changyuan Guo Fu Xu Ziyi Wang Yan Lu Kai Li Junbo Liang Zhen Huang Xiao Chen Jinjie Yao Hanjie Hu Xiaowen Cheng Yufeng Wan Xinyan Chen Ning Zhang Shiying Miao Jianqiang Cai Linfang Wang Changzheng Liu Wei Song Hong Zhao | 2022 | Signal Transduction and Targeted Therapy2022，7，7： | 0 |
| 9 | Dual‑Atom Nanozyme Eye Drops Attenuate Inflammation and Break the Vicious Cycle in Dry Eye Disease显示文摘Dry eye disease(DED)is a major ocular pathology worldwide,causing serious ocular discomfort and even visual impairment.The incidence of DED is gradually increasing with the highfrequency use of electronic products.Although inflammation is core cause of the DED vicious cycle,reactive oxygen species(ROS)play a pivotal role in the vicious cycle by regulating inflammation from upstream.Therefore,current therapies merely targeting inflammation show the failure of DED treatment.Here,a novel dual-atom nanozymes(DAN)-based eye drops are developed.The antioxidative DAN is successfully prepared by embedding Fe and Mn bimetallic single-atoms in N-doped carbon material and modifying it with a hydrophilic polymer.The in vitro and in vivo results demonstrate the DAN is endowed with superior biological activity in scavenging excessive ROS,inhibiting NLRP3 inflammasome activation,decreasing proinflammatory cytokines expression,and suppressing cell apoptosis.Consequently,the DAN effectively alleviate ocular inflammation,promote corneal epithelial repair,recover goblet cell density and tear secretion,thus breaking the DED vicious cycle.Our findings open an avenue to make the DAN as an intervention form to DED and ROSmediated inflammatory diseases. | Dandan Chu Mengyang Zhao Shisong Rong Wonho Jhe Xiaolu Cai Yi Xiao Wei Zhang Xingchen Geng Zhanrong Li Xingcai Zhang Jingguo Li | 2024 | Nano-Micro Letters2024，16，6： | 0 |
| 10 | Possible role of extracellular vesicles in exogenous chemical exposure-associated health concern显示文摘Extracellular vesicles(EVs) are mediators of intercellular message communication by transferring lipids, proteins, genetic materials, and are therefore involved in a wide spectrum of physiological or pathological processes. Exogenous chemicals exposure may affect the function of EVs at the biogenesis, secretion, transport or reception stage, which could further result in abnormal information communication between cells, and thus induce toxicity and diseases. This review briefly explores the role of EVs in chemical exposure-associated health concern and progressive diseases. | Guangbo Qu Xingchen Zhao Yanna Liu Fang Hao Jie Gao Lili Yang Qunfang Zhou Guibin Jiang | 2019 | Journal of Environmental Sciences2019，31，6： | 0 |
| 11 | Molecular-level effects of acupuncture on depression: a genome-wide transcriptome analysis of pituitary gland in rats exposed to chronic restraint stress显示文摘OBJECTIVE: To investigate the antidepressant mechanism of acupuncture at the molecular level in the pituitary gland of rats exposed to chronic restraint stress(CRS).METHODS: Forty-eight rats were randomly divided into a control group(C), model group(M), fluoxetine group(F), and acupuncture group(A). CRS was induced in the model group by restraining rats for 28 days. Groups F and A were given fluoxetine administration and acupuncture intervention, respectively, 1 h before the CRS procedures were implemented. On the 29 th day, rat pituitary glands were harvested for RNA extraction and RNA-sequencing analysis.RESULTS: Differentially expressed gene analysis identified 148, 87, and 179 response genes differen-tially expressed in group C vs group M, group F vs group M, and group A vs group M, respectively. Using Gene Ontology term enrichment analysis and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis, we identified the up-regulation of gene sets involved in extracellular space,receptor binding, and monoamine neurotransmitter metabolism, and the down-regulation of gene sets involved in immune response and inflammatory response as the prevailing transcriptomic signatures in the pituitary gland of rats treated with CRS,fluoxetine, or acupuncture.CONCLUSION: Our findings suggest that acupuncture has a multitarget antidepressant effect at the molecular and behavioral levels. | Wang Yu Jiang Huili Meng Hong Li Jing Yang Xinjing Zhao Bingcong Yu Qiuyun Liang Xingchen Bao Tuya | 2017 | Journal of Traditional Chinese Medicine2017，37，4： | 0 |
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