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| 1 | Synthesis,photophysical properties and TD-DFT calculation of four two-photon absorbing triphenylamine derivatives显示文摘In this study,linear absorption,single-photon excited fluorescence,fluorescence quantum yields,fluorescence lifetime and two-photon excited fluorescence of a series of triphenylamine derivatives (L1,L2,L3 and L4) have been measured.L1 and L3 are D--A type dyes,while L2 and L4 are D--D--A type dyes (D=donor,A=acceptor).The investigated compounds consist of triphenylamine-bearing donor-substituted and/or systematically extended-conjugated length,which are designed to gain insight into the effect of the ethoxyl unit and-linkage length on the linear and nonlinear optical properties.The influence of solvent polarity on the photophysical properties was investigated.Employing time-dependent density functional theory (TD-DFT) calculations,the structure-property relationships are discussed. | KONG Lin YANG JiaXiang ZHOU HongPing LI ShengLi HAO FuYing ZHANG Qiong TU YuLong WU JieYing XUE ZhaoMing TIAN YuPeng | 2013 | Science China Chemistry2013，56，1： | 3 |
| 2 | Microstructure evolution,texture and mechanical properties of a Mg-Gd-Y-Zn-Zr alloy fabricated by cyclic expansion extrusion with an asymmetrical extrusion cavity:The influence of passes and processing route显示文摘In the present work,two processing routes(A and B)with 3 CEE-AEC passes are performed on Mg-13 Gd-4 Y-2 Zn-0.4 Zr alloys,and the resultant microstructure evolution,texture analysis and mechanical properties are investigated systematically.The core difference between the two processing routes is the orientation between the expansion and extrusion steps,i.e.,they are parallel to each other for on route A and perpendicular to each other for route B.The results show that a remarkable grain refinement is achieved via both processing routes due to dynamic recrystallization(DRX).Fine equiaxed grains are observed in the samples processed with route B with a final size of 3.6±0.4μm compared to the grain size of 4.5±0.5μm with route A.With an increasing number of CEE-AEC passes,the overall texture intensity decreases,and the basal texture gradually changes to the mixed texture components.The shear deformation introduced by the asymmetrical extrusion cavity promotes a broad angular distribution of the basal planes on routes A and B,leading to an obvious increase in the Schmid factor for the activation of the basal a slip system.The tensile test at ambient temperature reveals that the comprehensive mechanical properties are improved,and the conventional mechanical anisotropy of as-received alloys is alleviated by successive CEE-AEC processing,which is mainly derived from the competitive balance relation between the grain refinement and texture modification. | Zhaoming Yan Xubin Li Jie Zheng Zhimin Zhang Qiang Wang Kaihua Xu Hongzhi Fan Guanshi Zhang Jiaxuan Zhu Yong Xue | 2021 | Journal of Magnesium and Alloys2021，9，3： | 2 |
| 3 | Histones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cells显示文摘Neutrophil extracellular traps(NETs)can capture and kill viruses,such as influenza viruses,human immunodeficiency virus(HIV),and respiratory syncytial virus(RSV),thus contributing to host defense.Contrary to our expectation,we show here that the histones released by NETosis enhance the infectivity of SARS-CoV-2,as found by using live SARS-CoV-2 and two pseudovirus systems as well as a mouse model.The histone H3 or H4 selectively binds to subunit 2 of the spike(S)protein,as shown by a biochemical binding assay,surface plasmon resonance and binding energy calculation as well as the construction of a mutant S protein by replacing four acidic amino acids.Sialic acid on the host cell surface is the key molecule to which histones bridge subunit 2 of the S protein.Moreover,histones enhance cell-cell fusion.Finally,treatment with an inhibitor of NETosis,histone H3 or H4,or sialic acid notably affected the levels of sgRNA copies and the number of apoptotic cells in a mouse model.These findings suggest that SARS-CoV-2 could hijack histones from neutrophil NETosis to promote its host cell attachment and entry process and may be important in exploring pathogenesis and possible strategies to develop new effective therapies for COVID-19. | Weiqi Hong Jingyun Yang Jun Zou Zhenfei Bi Cai He Hong Lei Xuemei He Xue Li Aqu Alu Wenyan Ren Zeng Wang Xiaohua Jiang Kunhong Zhong Guowen Jia Yun Yang Wenhai Yu Qing Huang Mengli Yang Yanan Zhou Yuan Zhao Dexuan Kuang Junbin Wang Haixuan Wang Siyuan Chen Min Luo Ziqi Zhang Tiangi Lu Li Chen Haiying Que Zhiyao He Qiu Sun Wei Wang Guobo Shen Guangwen Lu Zhiwei Zhao Li Yang Jinliang Yang Zhenling Wang Jiong Li Xiangrong Song Lunzhi Dai Chong Chen Jia Geng Maling Gou Lu Chen Haohao Dong Yong Peng Canhua Huang Zhiyong Qian Wei Cheng Changfa Fan Yuquan Wei Zhaoming Su Aiping Tong Shuaiyao Lu Xiaozhong Peng Xiawei Wei | 2022 | Cellular & Molecular Immunology2022，19，5： | 2 |
| 4 | A joint call for actions to advance taxonomy in China显示文摘Taxonomy plays an important role in understanding the origin, evolution, and ecological functionality of biodiversity. There are large number of unknown species yet to be described by taxonomists, which together with their ecosystem services cannot be effectively protected prior to description. Despite this, taxonomy has been increasingly underrated insufficient funds and permanent positions to retain young talents. Further, the impact factordriven evaluation systems in China exacerbate this downward trend, so alternative evaluation metrics are urgently necessary. When the current generation of outstanding taxonomists retires,there will be too few remaining taxonomists left to train the next generation. In light of these challenges, all co-authors worked together on this paper to analyze the current situation of taxonomy and put out a joint call for immediate actions to advance taxonomy in China. | Chaodong Zhu Arong Luo Ming Bai Michael COrr Zhonge Hou Siqin Ge Jun Chen Yibo Hu Xuming Zhou Gexia Qiao Hongzhi Kong Limin Lu Xiaohua Jin Lei Cai Xinli Wei Ruilin Zhao Wei Miao Qingfeng Wang Zhongli Sha Qiang Lin Meng Qu Jianping Jiang Jiatang Li Jing Che Xuelong Jiang Xiaoyong Chen Lianming Gao Zongxin Ren Chunlei Xiang Shixiao Luo Donghui Wu Dong Liu Yanqiong Peng Tao Su Chenyang Cai Tianqi Zhu Wanzhi Cai Xingyue Liu Hu Li Huaijun Xue Zhen Ye Xuexin Chen Pu Tang Shujun Wei Hong Pang Qiang Xie Feng Zhang Feng Zhang Xianjin Peng Aibing Zhang Taiping Gao Changfa Zhou Chen Shao Libin Ma Zhaoming Wei Yunxia Luan Ziwei Yin Wu Dai Cong Wei Xiaolei Huang Jingxian Liu Xiangsheng Chen Tianci Yi Zhisheng Zhang Zhulidezi Aishan Qin Li Hongying Hu | 2022 | Zoological Systematics2022，47，3： | 1 |
| 5 | Effect of heat treatment on mechanical properties and microstructure evolution of Mg-9.5Gd-4Y-2.2Zn-0.5Zr alloy显示文摘Regarding the as-cast Mg-9.5Gd-4Y-2.2Zn-0.5Zr alloy,the effect of heat treatment on its properties at room temperature(RT),as well as the mechanical properties and microstructure evolution of various peak-aging samples at different tensile temperatures were discussed in this article.The results indicated that the optimal heat treatment process of the alloy was:520℃×24 h+200℃×112 h.Under this condition,the yield strength(YS),ultimate tensile strength(UTS)and elongation(EL)at RT were:238 MPa,327 MPa and 2.5%,respectively.As the tensile temperature increases,the strength increases firstly and then decreases,but the ductility increases monotonously.The microstructures evolution of 200℃ peak-aging(200PA)and 250℃ peak-aging(250PA)samples were different with the increasing tensile tenperature.When tensile test processed at 150℃,the denseβ’phase and rod-shaped basalγ’phase will be formed in the 200PA sample.However,at 300℃,theβ’phases disappeared.Theβ’and LPSO phases in the 250PA sample coarsened gradually as the tensile temperature increased,and 14H-LPSO phases were formed during tensile at 300℃.The 200PA sample reached the highest strength when tensile at 150℃,which was attributed to the hindrance of the basal dislocation and non-basal dislocation slip by the prismaticβ’phases and the newly formed basalγ’precipitates. | Jie Zheng Zhaoming Yan Jinsheng Ji Yusha Shi Heng Zhang Zhimin Zhang Yong Xue | 2022 | Journal of Magnesium and Alloys2022，10，4： | 1 |
| 6 | Phototriggered Formation of a Supramolecular Polymer Network Based on Orthogonal H-Bonding and Host-Guest Recognition显示文摘Supramolecular polymer networks(SPNs)have gained increasing research attention due to their reversible and tunable nature in the preparation of adaptive materials.The use of hierarchical self-assembly techniques is an emerging strategy for the fabrication of smart supramolecular polymer networks,but corresponding study is still rare.Herein,we have reported a novel supramolecular polymer network through complementary host-guest interactions and phototriggered quadruple H-bonding cross-linking.Specifically,we design and synthesize an H1G1-type monomer consisting of a benzo-21-crown-7(B21C7)host(H1),a dialkylammonium salt guest(G1)and a photolabile o-nitrobenzyl ether protected ureidopyrimidinone(Upy)moiety.B21C7 and ammonium moieties can first form a linear supramolecular polymer through complementary host-guest interactions.Under photoirradiation,the Upy groups on the SP side chains were released,and the obtained linear supramolecular polymer could be further transformed into SPN through a quadruple H-bonding cross-linking.Meanwhile,the in situ transformation in the solid state is also accompanied by pronounced enhancement in mechanical properties,which provides foundation for further application of materials in different scenarios. | BAI Ruixue YANG Xue ZHAO Jun ZHANG Zhaoming YAN Xuzhou | 2023 | Chemical Research in Chinese Universities2023，39，5： | 0 |
| 7 | Enhancement of T cell infiltration via tumor-targeted Th9 cell delivery improves the efficacy of antitumor immunotherapy of solid tumors显示文摘Insufficient infiltration of T cells severely compromises the antitumor efficacy of adoptive cell therapy(ACT)against solid tumors.Here,we present a facile immune cell surface engineering strategy aiming to substantially enhance the anti-tumor efficacy of Th9-mediated ACT by rapidly identifying tumor-specific binding ligands and improving the infiltration of infused cells into solid tumors.Non-genetic decoration of Th9 cells with tumor-targeting peptide screened from phage display not only allowed precise targeted ACT against highly heterogeneous solid tumors but also substantially enhanced infiltration of CD8+T cells,which led to improved antitumor outcomes.Mechanistically,infusion of Th9 cells modified with tumor-specific binding ligands facilitated the enhanced distribution of tumor-killing cells and remodeled the immunosuppressive microenvironment of solid tumors via IL-9 mediated immunomodulation.Overall,we presented a simple,cost-effective,and cell-friendly strategy to enhance the efficacy of ACT against solid tumors with the potential to complement the current ACT. | Tao Chen Yucheng Xue Shengdong Wang Jinwei Lu Hao Zhou Wenkan Zhang Zhiyi Zhou Binghao Li Yong Li Zenan Wang Changwei Li Yinwang Eloy Hangxiang Sun Yihang Shen Mohamed Diaty Diarra Chang Ge Xupeng Chai Haochen Mou Peng Lin Xiaohua Yu Zhaoming Ye | 2023 | Bioactive Materials2023，，5： | 0 |
| 8 | Remote Sensing of Sea Surface Wind of Hurricane Michael by GPS Reflected Signals显示文摘In this paper, the propagating geometry and the w av eform of the GPS reflected signals are expatiated in detail. Furthermore, the pr inciple and the method of retrieving sea surface wind are presented. In order to test the feasibility of retrieval, the experiment data obtained by NASA in Hurr icane Michael are used. The result shows that the retrieval accuracy of wind spe ed is about 2 m/s. | ZHOU Zhaoming FU Yang XUE Zhengang CUI Hongguang | 2006 | Geo-Spatial Information Science2006，9，1： | 0 |
| 9 | Weldable and closed-loop recyclable monolithic dynamic covalent polymer aerogels显示文摘Owing to their low density,high porosity and unique micro-nanostructures,aerogels are attractive for application in various fields;however,they suffer from shrinkage and/or cracking during preparation,mechanical brittleness,low production efficiency and non-degradation.Herein,we introduce the concept of dynamic covalent polymer chemistry to produce a new class of aerogels—referred to as DCPAs.The resulting lightweight DCPAs have the potential to be prepared on a large scale and feature high porosity(90.7%–91.3%),large degrees of compression(80%strain)and bending(diametral deflection of 30 mm)without any cracks,as well as considerable tensile properties(an elongation with a break at 32.7%).In addition,the DCPAs showcase the emergent characteristics of weldability,repairability,degradability and closed-loop recyclability that are highly desirable for providing versatile material platforms,though hardly achieved by traditional aerogels.Taking advantage of their robust porous structures,we demonstrate the potential of DCPAs for applications in thermal insulation and emulsion separation.These findings reveal that the dynamic covalent bond strategy would be generalized for the production of a new generation of aerogels with customized features for functioning in the field of intelligent and sustainable materials. | Xinhai Zhang Jun Zhao Kai Liu Guangfeng Li Dong Zhao Zhaoming Zhang Junjun Wan Xue Yang Ruixue Bai Yongming Wang Wei Zhang Xuzhou Yan | 2022 | National Science Review2022，9，9： | 0 |
| 10 | A soybean NAC homolog contributes to resistance to Phytophthora sojae mediated by dirigent proteins显示文摘Phytophthora sojae infection severely impairs soybean production. We previously identified a dirigent protein, Gm DRR1(Glycine max Disease Resistant Response 1), that increases soybean resistance to P.sojae. However, the molecular basis of Gm DRR1 function remained largely uncharacterized. In the present study, analysis of Gm DRR1-RNAi, Gm DRR1-overexpressing, and CRISPR/Cas9-derived Gmdrr1 mutant lines revealed that Gm DRR1 expression significantly restricted P. sojae growth. Combining coimmunoprecipitation with liquid chromatography–tandem mass spectrometry revealed a Gm DRR1-interacting protein, Gm DRR2, which is homologous to Gm DRR1. An E-coniferyl alcohol coupling assay indicated that Gm DRR1 promotes the synthesis of(+)-pinoresinol, which helps to protect plants from P. sojae. The Gm NAC1(Glyma.05 G025500) transcription factor bound to the Gm DRR1 promoter both in vitro and in vivo to upregulate Gm DRR1 expression. Soybean resistance to P. sojae was increased by overexpression of Gm NAC1. Our findings suggest a novel signaling pathway involving a NAC transcription factor that mediates soybean resistance to P. sojae. Specifically, Gm NAC1 directly induces Gm DRR1 expression to increase resistance of soybean plants to P. sojae. | Guolong Yu Jianan Zou Jinhui Wang Rongsheng Zhu Zhaoming Qi Hongwei Jiang Zhenbang Hu Mingliang Yang Ying Zhao Xiaoxia Wu Chunyan Liu Candong Li Xue Yang Zhendong Zhu Qingshan Chen Yongfu Fu Dawei Xin | 2022 | The Crop Journal2022，10，2： | 0 |
| 11 | Transcriptome-wide N6-methyladenosine(m^(6)A)methylation in soybean under Meloidogyne incognita infection显示文摘N^(6)-methyladenosine(m^(6)A)is a reversible epigenetic modification of mRNA and other RNAs that plays a significant role in regulating gene expression and biological processes.However,m^(6)A abundance,dynamics,and transcriptional regulatory mechanisms remain unexplored in the context of soybean resistance to Meloidogyne incognita.In this study,we performed a comparative analysis of transcriptome-wide m^(6)A and metabolome profiles of soybean root tissues with and without M.incognita infection.Global m^(6)A hypermethylation was widely induced in response to M.incognita infection and was enriched around the 3′end of coding sequences and in 3′UTR regions.There were 2069 significantly modified m^(6)A sites,594 differentially expressed genes,and 103 differentially accumulated metabolites between infected and uninfected roots,including coumestrol,psoralidin,and 2-hydroxyethylphosphonate.Among 101 m^(6)A-modified DEGs,34 genes were hypomethylated and upregulated,and 39 genes were hypermethylated and downregulated,indicating a highly negative correlation between m^(6)A methylation and gene transcript abundance.A number of these m^(6)A-modified DEGs,including WRKY70,ERF60,POD47 and LRR receptor-like serine/threonine-protein kinases,were involved in plant defense responses.Our study provides new insights into the critical role of m^(6)A modification in early soybean responses to M.incognita. | Xue Han Qianqian Shi Ziyi He Wenwen Song Qingshan Chen Zhaoming Qi | 2022 | aBIOTECH2022，3，3： | 0 |
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