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2922篇 您的检索式:作者名="XUE X"
    题名 作者 年代 出处 被引量
1An ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants显示文摘Abscisic 酸(骆驼毛的织物) 是最重要的荷尔蒙让植物抵抗干旱和另外的不能生活的压力。骆驼毛的织物直接绑在骆驼毛的织物受体的 PYR/PYL 家庭,导致类型 2C 磷酸酶(PP2C ) 和下游的骆驼毛的织物发信号的激活的抑制。骆驼毛的织物由小分子发信号的干预能帮助植物克服象干旱,寒冷和土壤咸度那样的不能生活的压力,这被想象。然而,由植物酶的化学不稳定性和快速的分解代谢限制骆驼毛的织物本身的实际申请。这里,我们报导一件小分子骆驼毛的织物的鉴定模仿(AM1 ) 那充当骆驼毛的织物受体的家庭的多重成员的有势力使活跃之物。在 Arabidopsis, AM1 激活高度类似于由骆驼毛的织物导致了那的一个基因网络。有 AM1 的处理禁止种子萌芽,阻止叶水损失,并且支持干旱抵抗。我们与 PYL2 骆驼毛的织物受体和 HAB1 PP2C 在建筑群解决了 AM1 的水晶结构,它表明 AM1 调停交往的 gate-latch-lock 网络,在骆驼毛的织物界限 receptor/PP2C 建筑群被保存的一个结构的特征。一起,这些结果证明一件单个小分子骆驼毛的织物模仿能激活多重骆驼毛的织物受体并且保护植物免受水损失和干旱应力的伤害。而且, AM1 复杂水晶结构为设计 ABA-mimicking 小分子的下一代提供一个结构的基础。Minjie Cao Xue Liu Yan Zhang Xiaoqian Xue X EdwardZhou Karsten Melcher Pan Gao Fuxing Wang Liang Zeng Yang Zhao Pan Deng Dafang Zhong Jian-Kang Zhu H Eric Xu Yong Xu 2013Cell Research2013,23,8:17
2曹雪涛院士科研团队论文荣膺中国百篇最具影响国际学术论文--长链非编码RNA1nc-DC通过STAT3调控人DC的分化和功能显示文摘树突状细胞(DC)是免疫系统中重要的抗原提呈细胞,其成熟和功能状态决定着免疫应答的走向和强度。哺乳动物基因组能够转录产生大量的长链非编码RNA(long noncoding RNA,IncRNA),其在免疫系统中的功能还知之甚少。 曹雪涛院十科研团队王品副教授课题组采用了转录组芯片二代测序高通量筛选方法、RNA-pulldown、ChIP-seq等技术展开了对IncRNA在DC分化和功能中作用的研究,发现并鉴定了特异性高表达于DC的1ncRNA,命名为1nc-DC,其可通过抑制STAT3去磷酸化,从而促进DC分化和功能。该研究成果发表于Science杂志[2014,344(6181):310-313],并于2015年12月被评为“中国百篇最具影响国际学术论文”。wang p xue y han y lin l wu c xu s jiang z xu j liu q cao x 2016中国肿瘤生物治疗杂志2016,23,1:10
3Transfer hydrogenation of activatied C=C bonds catalyzed by ruthenium amido complexes: Reaction scope, limitation, and enantioselectivity 显示文摘Xue D Chen Y C Cui X 2005Journal of Organic Chemistry2005,70,9:1
4Tribological behavior of microarc oxidation coatings on aluminum alloy显示文摘Xue W Du J Wu X 2006ISIJ Int2006,46,:1
5Bolus dose remifentanil and sufentanil blunting cardiovascular intubation responses in children:a randomized,double-blind comparison显示文摘Liao X Yang QY Xue FS 2009Ear J Anaesthesiol2009,26,1:1
6The preventive effect of adjuvant-free administration of TNF-PADRE autovaccine on collagen-Ⅱ-induced rheumatoid arthritis in mice显示文摘Wan Y Yuan S Xue X 2009Cell Immunol2009,258,1:1
7Empirical Likelihood for a Varying Coefficient Model with Longitudinal Data显示文摘Xue L G Zhu L X 2007J Am Statist Ass2007,102,:1
8Theoretical prediction of the springback of metal sheets after a double-curvature forming operation显示文摘Xue P Yu T X 1999Journal of Material Processing Technology1999,8990,:1
9Enhanced 1,3-propanediol production by supply of organic acids and repeated fed-batch culture显示文摘Xue X D Li W Li Z M 2010J Ind Microbiol Biotechnol2010,37,7:1
10System Level Lumped-parameter Dynamic Modeling of PEM Fuel Cell显示文摘Xue X Tang J Simirnova A 2004J Power Sources2004,133,:1
11A clinical and experimental study on all-trans retinoic acid- treated acute promyelocytic leukemia patients显示文摘CHEN Z X XUE Y Q ZHANG R 1991Blood1991,78,6:1
12Nonlocal nonlinear differential equations with a measure of noncompactness in Banach spaces显示文摘Xue X M 2009Nonlinear Anal2009,70,7:1
13Folate deficiency induces aneuploidy in human lymphocytes in vitro--evidence using cytokinesis-blocked cells and probes specific for chromosome 17 and 21显示文摘Wang X Thomas P Xue JL 2004Mutat Res2004,551,12:1
14A pair of new BAC and BIBAC vectors that facilitate BAC/BIBAC library construction and intact large genomic DNA in- sert exchange显示文摘Shi X Zeng H Y Xue Y I3 2011Plant Methods2011,7,:1
15Molecular cloning and characterization of the myostatin gene in croceine croaker,Pseudosciaena crocea显示文摘Xue L Y Qian K X Qian Hong Q 2006Molecular Biology Reports2006,33,2:1
16Differences of immunophenotypic markers and signaling molecules between adenocarcinomas of gastric cardia and distal stomach显示文摘XUE L ZHANG X LI Y 2011Hum Pathol2011,42,4:1
17The influence of hemocoagulation disorders on the development of posttranmatic cerebral infarction and outcome in patients with moderate or severe head trauma 显示文摘Chen H Xue L X Guo Y 2013Biomed Res Int2013,2013,68:1
18The estimation of duodenal utilizable true protein in sheep fedmixed rations using the nitrogenous fractions of the Cornell Net Carbohy-drate and Protein System显示文摘G.Y Zhao Yao Xue Y X Li 0,,:1
19Gene - modified mesenchymal stem cells protect against radiation -induced lung injury显示文摘Xue J Li X Lu Y 2013Mol Ther2013,21,2:1
20Reductive dechlorination of organochlorine pesticides in soils from an abandoned manufacturing facility by zero-valent iron显示文摘Xue N Cong X Wang S 2010Science of the Total Environment2010,408,16:1
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